Case Report: Asymptomatic Mediastinal Tumor: Role of Preventive Screening in Early Detection and Survival Forecast

Zeynapur Aida Ali-Agaevna; Drapkina Oxana Mikhailovna; Shutov Sergei Alexandrovich; Kovrigina Alla Mikhailovna

doi:doi:10.11648/j.ajhr.20200805.11

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Case Report: Asymptomatic Mediastinal Tumor: Role of Preventive Screening in Early Detection and Survival Forecast

Zeynapur Aida Ali-Agaevna, Drapkina Oxana Mikhailovna, Shutov Sergei Alexandrovich, Kovrigina Alla Mikhailovna

Published in American Journal of Health Research (Volume 8, Issue 5)

Received: 9 September 2020 Accepted: 9 October 2020 Published: 23 October 2020

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Abstract

The main presentation is to use the opportunities and advantages of the annual dispensary examination. Screening of the population allows early detection of the disease associated with reduced working capacity, disability and high mortality among the adult population. Later diagnosis at the stage of advanced manifestations or complications worsens the prognosis and survival. Currently, according to the World Health Organization (WHO), diseases of the cardiovascular system, cancer and diabetes mellitus, along with infectious diseases, contribute to the main morbidity and mortality worldwide. The preventive medicine strategy allows, on the one hand, to have a positive effect on the health of the population and overall life expectancy, on the other hand, to significantly reduce the financial burden on the entire health care system. At the same time, tumor lesions of mediastinum are mostly asymptomatic until they spread beyond the capsule and grow into neighboring vital organs - the heart, aorta, pulmonary arteries, lungs and esophagus. In this clinical case report, the use of the method of regular annual preventive examinations (complete blood count, urine, electrocardiography, chest X-ray, etc.) in this clinical case made it possible to identify tumor lesions of the anterior mediastinum at the stage of preclinical or early clinical manifestations leading to disability and mortality. As a result of the timely provision of medical care based on the latest recommendations of the national specialized communities, the total removal of the tumor formation made it possible not only to improve the prognosis, but also to achieve complete recovery.

Published in	American Journal of Health Research (Volume 8, Issue 5)
DOI	10.11648/j.ajhr.20200805.11
Page(s)	78-83
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Thymoma, Ophthalmoplegic Myasthenia Gravis, Horner's Syndrome, Thoracoscopic Resection of Mediastinal Tumors

References

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[3]	Howlader N, Noone AM, Krapcho M, Miller D, Brest A, Yu M, Ruhl J, Tatalovich Z, Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2017, National Cancer Institute. Bethesda, MD, https://seer.cancer.gov/csr/1975_2017/, based on November 2019 SEER data submission, posted to the SEER web site, April 2020.
[4]	J. F. Horner: Über eine Form von Ptosis. In: Klinische Monatsblätter für Augenheilkunde, Stuttgart, 1869, Band 7, S: 193-198.
[5]	Filosso, P. L., Venuta, F., Oliaro, A., Ruffini, E., Rendina, E. A., Margaritora, S., Casadio, C., Terzi, A., Rena, O., Lococo, F., & Guerrera, F. Thymoma and inter-relationshis between clinical variables: A multicentre study in 537 patients. Eur J Cardiothorac Surg. 2014 Jun; 45 (6): 1020-7. doi: 10.1093/ejcts/ezt567.
[6]	Matthew Meriggioli, Donald B Sanders. Muscle Autoantibodies In Myasthenia Gravis: beyond diagnosis? Expert Rev Clin Immunol. 2012 Jul; 8 (5): 427-38. doi: 10.1586/eci.12.34.
[7]	Iwaya Y, Tekenaka K, Akamatsu T., et al. Primary gastric diffuse large B-cell lymphoma with orbital involvement: diagnostic usefulness of 18F-fluorodeoxyglucose positron emission tomography. Intern Med. 2011; 50 (18): 1953-6. doi: 10.2169/internalmedicine.50.5524.
[8]	Cheson BD, Fisher RI, Barrington SF, et al. Recommendations for initial evaluation, staging, and response assessment of Hodgkin and non-Hodgkin Lymphoma: the Lugano classification. J Clin Oncol. 2014; 32 (27): 3059–67. doi: 10.1200/JCO.2013.54.8800.
[9]	Marta Scorsetti, Francesco Leo, Annalisa Trama, et al. Thymoma and thymic carcinomas. Crit Rev Oncol Hematol. 2016 Mar; 99: 332-50. doi: 10.1016/j.critrevonc.2016.01.012.
[10]	A Masaoka, Y Monden, K Nakahara, T Tanioka. Follow-up study of thymomas with special reference to their clinical stages. Cancer. 1981 Dec 1; 48 (11): 2485-92. doi: 10.1002/1097-0142(19811201)48:11<2485::aid-cncr2820481123>3.0.co;2-r.
[11]	Alexander Marx, John K. C. Chan, Jean-Michel Coindre, Frank Detterbeck, Nicolas Girard, Nancy L. Harris, Elaine S. Jaffe, Michael O. Kurrer, Edith M. Marom, Andre L. Moreira, Kiyoshi Mukai, Attilio Orazi, Philipp Ströbel. The 2015 World Health Organization Classification of Tumors of the Thymus: Continuity and Changes. Journal of Thoracic Oncology Volume 10, Issue 10, October 2015, Pages 1383-1395. https://doi.org/10.1097/JTO.0000000000000654.
[12]	Gu Z, Fu J, Shen Y, Wei Y, Tan L, Zhang P, Han Y, Chen C, Zhang R, Li Y, Chen K, Chen H, Liu Y, Cui Y, Wang Y, Pang L, Yu Z, Zhou X, Liu Y, Liu Y, Fang W; Members of the Chinese Alliance for Research in Thymomas. Thymectomy versus tumor resection for early-stage thymic malignancies: a Chinese Alliance for Research in Thymomas retrospective database analysis. J Thorac Dis. 2016 Apr; 8 (4): 680-6. doi: 10.21037/jtd.2016.03.16.
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APA Style

Zeynapur Aida Ali-Agaevna, Drapkina Oxana Mikhailovna, Shutov Sergei Alexandrovich, Kovrigina Alla Mikhailovna. (2020). Case Report: Asymptomatic Mediastinal Tumor: Role of Preventive Screening in Early Detection and Survival Forecast. American Journal of Health Research, 8(5), 78-83. https://doi.org/10.11648/j.ajhr.20200805.11

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ACS Style

Zeynapur Aida Ali-Agaevna; Drapkina Oxana Mikhailovna; Shutov Sergei Alexandrovich; Kovrigina Alla Mikhailovna. Case Report: Asymptomatic Mediastinal Tumor: Role of Preventive Screening in Early Detection and Survival Forecast. Am. J. Health Res. 2020, 8(5), 78-83. doi: 10.11648/j.ajhr.20200805.11

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AMA Style

Zeynapur Aida Ali-Agaevna, Drapkina Oxana Mikhailovna, Shutov Sergei Alexandrovich, Kovrigina Alla Mikhailovna. Case Report: Asymptomatic Mediastinal Tumor: Role of Preventive Screening in Early Detection and Survival Forecast. Am J Health Res. 2020;8(5):78-83. doi: 10.11648/j.ajhr.20200805.11

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@article{10.11648/j.ajhr.20200805.11,
  author = {Zeynapur Aida Ali-Agaevna and Drapkina Oxana Mikhailovna and Shutov Sergei Alexandrovich and Kovrigina Alla Mikhailovna},
  title = {Case Report: Asymptomatic Mediastinal Tumor: Role of Preventive Screening in Early Detection and Survival Forecast},
  journal = {American Journal of Health Research},
  volume = {8},
  number = {5},
  pages = {78-83},
  doi = {10.11648/j.ajhr.20200805.11},
  url = {https://doi.org/10.11648/j.ajhr.20200805.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajhr.20200805.11},
  abstract = {The main presentation is to use the opportunities and advantages of the annual dispensary examination. Screening of the population allows early detection of the disease associated with reduced working capacity, disability and high mortality among the adult population. Later diagnosis at the stage of advanced manifestations or complications worsens the prognosis and survival. Currently, according to the World Health Organization (WHO), diseases of the cardiovascular system, cancer and diabetes mellitus, along with infectious diseases, contribute to the main morbidity and mortality worldwide. The preventive medicine strategy allows, on the one hand, to have a positive effect on the health of the population and overall life expectancy, on the other hand, to significantly reduce the financial burden on the entire health care system. At the same time, tumor lesions of mediastinum are mostly asymptomatic until they spread beyond the capsule and grow into neighboring vital organs - the heart, aorta, pulmonary arteries, lungs and esophagus. In this clinical case report, the use of the method of regular annual preventive examinations (complete blood count, urine, electrocardiography, chest X-ray, etc.) in this clinical case made it possible to identify tumor lesions of the anterior mediastinum at the stage of preclinical or early clinical manifestations leading to disability and mortality. As a result of the timely provision of medical care based on the latest recommendations of the national specialized communities, the total removal of the tumor formation made it possible not only to improve the prognosis, but also to achieve complete recovery.},
 year = {2020}
}

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TY  - JOUR
T1  - Case Report: Asymptomatic Mediastinal Tumor: Role of Preventive Screening in Early Detection and Survival Forecast
AU  - Zeynapur Aida Ali-Agaevna
AU  - Drapkina Oxana Mikhailovna
AU  - Shutov Sergei Alexandrovich
AU  - Kovrigina Alla Mikhailovna
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DO  - 10.11648/j.ajhr.20200805.11
T2  - American Journal of Health Research
JF  - American Journal of Health Research
JO  - American Journal of Health Research
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EP  - 83
PB  - Science Publishing Group
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UR  - https://doi.org/10.11648/j.ajhr.20200805.11
AB  - The main presentation is to use the opportunities and advantages of the annual dispensary examination. Screening of the population allows early detection of the disease associated with reduced working capacity, disability and high mortality among the adult population. Later diagnosis at the stage of advanced manifestations or complications worsens the prognosis and survival. Currently, according to the World Health Organization (WHO), diseases of the cardiovascular system, cancer and diabetes mellitus, along with infectious diseases, contribute to the main morbidity and mortality worldwide. The preventive medicine strategy allows, on the one hand, to have a positive effect on the health of the population and overall life expectancy, on the other hand, to significantly reduce the financial burden on the entire health care system. At the same time, tumor lesions of mediastinum are mostly asymptomatic until they spread beyond the capsule and grow into neighboring vital organs - the heart, aorta, pulmonary arteries, lungs and esophagus. In this clinical case report, the use of the method of regular annual preventive examinations (complete blood count, urine, electrocardiography, chest X-ray, etc.) in this clinical case made it possible to identify tumor lesions of the anterior mediastinum at the stage of preclinical or early clinical manifestations leading to disability and mortality. As a result of the timely provision of medical care based on the latest recommendations of the national specialized communities, the total removal of the tumor formation made it possible not only to improve the prognosis, but also to achieve complete recovery.
VL  - 8
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Author Information

Zeynapur Aida Ali-Agaevna

Federal Medical Establishment “National Medical Scientific and Research Center of Therapy and Preventive Medicine” of the Ministry of Health of the Russian Federation, Moscow, Russia
Drapkina Oxana Mikhailovna

The Federal Medical Establishment “National Medical Scientific and Research Center of Therapy and Preventive Medicine” of the Ministry of Health of the Russian Federation, Moscow, Russia
Shutov Sergei Alexandrovich

Federal Medical Establishment “National Medical Research Center for Hematology” of the Ministry of Health of the Russian Federation, Moscow, Russia
Kovrigina Alla Mikhailovna

Federal Medical Establishment “National Medical Research Center for Hematology” of the Ministry of Health of the Russian Federation, Moscow, Russia

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APA Style

Zeynapur Aida Ali-Agaevna, Drapkina Oxana Mikhailovna, Shutov Sergei Alexandrovich, Kovrigina Alla Mikhailovna. (2020). Case Report: Asymptomatic Mediastinal Tumor: Role of Preventive Screening in Early Detection and Survival Forecast. American Journal of Health Research, 8(5), 78-83. https://doi.org/10.11648/j.ajhr.20200805.11

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ACS Style

Zeynapur Aida Ali-Agaevna; Drapkina Oxana Mikhailovna; Shutov Sergei Alexandrovich; Kovrigina Alla Mikhailovna. Case Report: Asymptomatic Mediastinal Tumor: Role of Preventive Screening in Early Detection and Survival Forecast. Am. J. Health Res. 2020, 8(5), 78-83. doi: 10.11648/j.ajhr.20200805.11

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AMA Style

Zeynapur Aida Ali-Agaevna, Drapkina Oxana Mikhailovna, Shutov Sergei Alexandrovich, Kovrigina Alla Mikhailovna. Case Report: Asymptomatic Mediastinal Tumor: Role of Preventive Screening in Early Detection and Survival Forecast. Am J Health Res. 2020;8(5):78-83. doi: 10.11648/j.ajhr.20200805.11

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@article{10.11648/j.ajhr.20200805.11,
  author = {Zeynapur Aida Ali-Agaevna and Drapkina Oxana Mikhailovna and Shutov Sergei Alexandrovich and Kovrigina Alla Mikhailovna},
  title = {Case Report: Asymptomatic Mediastinal Tumor: Role of Preventive Screening in Early Detection and Survival Forecast},
  journal = {American Journal of Health Research},
  volume = {8},
  number = {5},
  pages = {78-83},
  doi = {10.11648/j.ajhr.20200805.11},
  url = {https://doi.org/10.11648/j.ajhr.20200805.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajhr.20200805.11},
  abstract = {The main presentation is to use the opportunities and advantages of the annual dispensary examination. Screening of the population allows early detection of the disease associated with reduced working capacity, disability and high mortality among the adult population. Later diagnosis at the stage of advanced manifestations or complications worsens the prognosis and survival. Currently, according to the World Health Organization (WHO), diseases of the cardiovascular system, cancer and diabetes mellitus, along with infectious diseases, contribute to the main morbidity and mortality worldwide. The preventive medicine strategy allows, on the one hand, to have a positive effect on the health of the population and overall life expectancy, on the other hand, to significantly reduce the financial burden on the entire health care system. At the same time, tumor lesions of mediastinum are mostly asymptomatic until they spread beyond the capsule and grow into neighboring vital organs - the heart, aorta, pulmonary arteries, lungs and esophagus. In this clinical case report, the use of the method of regular annual preventive examinations (complete blood count, urine, electrocardiography, chest X-ray, etc.) in this clinical case made it possible to identify tumor lesions of the anterior mediastinum at the stage of preclinical or early clinical manifestations leading to disability and mortality. As a result of the timely provision of medical care based on the latest recommendations of the national specialized communities, the total removal of the tumor formation made it possible not only to improve the prognosis, but also to achieve complete recovery.},
 year = {2020}
}

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TY  - JOUR
T1  - Case Report: Asymptomatic Mediastinal Tumor: Role of Preventive Screening in Early Detection and Survival Forecast
AU  - Zeynapur Aida Ali-Agaevna
AU  - Drapkina Oxana Mikhailovna
AU  - Shutov Sergei Alexandrovich
AU  - Kovrigina Alla Mikhailovna
Y1  - 2020/10/23
PY  - 2020
N1  - https://doi.org/10.11648/j.ajhr.20200805.11
DO  - 10.11648/j.ajhr.20200805.11
T2  - American Journal of Health Research
JF  - American Journal of Health Research
JO  - American Journal of Health Research
SP  - 78
EP  - 83
PB  - Science Publishing Group
SN  - 2330-8796
UR  - https://doi.org/10.11648/j.ajhr.20200805.11
AB  - The main presentation is to use the opportunities and advantages of the annual dispensary examination. Screening of the population allows early detection of the disease associated with reduced working capacity, disability and high mortality among the adult population. Later diagnosis at the stage of advanced manifestations or complications worsens the prognosis and survival. Currently, according to the World Health Organization (WHO), diseases of the cardiovascular system, cancer and diabetes mellitus, along with infectious diseases, contribute to the main morbidity and mortality worldwide. The preventive medicine strategy allows, on the one hand, to have a positive effect on the health of the population and overall life expectancy, on the other hand, to significantly reduce the financial burden on the entire health care system. At the same time, tumor lesions of mediastinum are mostly asymptomatic until they spread beyond the capsule and grow into neighboring vital organs - the heart, aorta, pulmonary arteries, lungs and esophagus. In this clinical case report, the use of the method of regular annual preventive examinations (complete blood count, urine, electrocardiography, chest X-ray, etc.) in this clinical case made it possible to identify tumor lesions of the anterior mediastinum at the stage of preclinical or early clinical manifestations leading to disability and mortality. As a result of the timely provision of medical care based on the latest recommendations of the national specialized communities, the total removal of the tumor formation made it possible not only to improve the prognosis, but also to achieve complete recovery.
VL  - 8
IS  - 5
ER  -

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