Transdermal delivery of topical medications is commonly used for managing osteoarthritis (OA). Osteoarthritis of the knee joint impairs lower limb functions which contributes to poor gait patterns. There is insufficient empirical data to support the efficacy of glucosamine sulphate and methyl salicilate cream in the management of knee OA. The aims of this study were to compare the immediate effects of glucosamine sulphate and methyl salicylate cream on pain, flexibility and knee flexion. Forty one subjects with grade ll knee OA were recruited for the study. They were randomly assigned to 2 groups. One gram of each topical formulation was administered to the knee joint using massage. Pre and post-intervention pain intensities, hamstring flexibilities and active knee flexion were measured. Descriptive, paired and independent t-tests statistics were used to analyze the data. There were significant reduction in pain intensities within the groups (t = 9.08, p<0.001; t =6.29, p<0.001). However, there was no significant difference in the post treatments pain intensities across the two groups. There were significant increase in the flexibilities of groups 1 and 2 post treatment (t= 9.14, p<0.001) and (t= -5.67, p<0.001) respectively but there was insignificant difference in the flexibilities of the groups. Similarly, there was insignificant difference in the range of motion when the active knee flexions of the two groups were compared. We concluded that transdermal massage of glucosamine was as effective as methyl salicilate in alleviating pains, improving hamstring flexibility and increasing knee flexion range of motion in a single treatment session among knee OA participants in this study.
| DOI | 10.11648/j.ajhr.s.2014020501.18 |
| Published in |
American Journal of Health Research (Volume 2, Issue 5-1, October 2014)
This article belongs to the Special Issue Supplementary Prescribing in Nigeria: A Needy Concept to Promote Clinical Physiotherapy Practice |
| Page(s) | 40-44 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Glucosamine Sulphate, Methyl Salicilate, Pain, Hamstring Flexibility, Knee Osteoarthritis
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APA Style
Onigbinde Ayodele Teslim, Adesina Olawale Daniel, Tarimo Nesto, Ojoawo Adesola. (2014). Comparative Effects of a Single Treatment Session Using Glucosamine Sulphate and Methyl Salicylate on Pain and Hamstring Flexibility of Patients with Knee Osteoarthritis. American Journal of Health Research, 2(5-1), 40-44. https://doi.org/10.11648/j.ajhr.s.2014020501.18
ACS Style
Onigbinde Ayodele Teslim; Adesina Olawale Daniel; Tarimo Nesto; Ojoawo Adesola. Comparative Effects of a Single Treatment Session Using Glucosamine Sulphate and Methyl Salicylate on Pain and Hamstring Flexibility of Patients with Knee Osteoarthritis. Am. J. Health Res. 2014, 2(5-1), 40-44. doi: 10.11648/j.ajhr.s.2014020501.18
AMA Style
Onigbinde Ayodele Teslim, Adesina Olawale Daniel, Tarimo Nesto, Ojoawo Adesola. Comparative Effects of a Single Treatment Session Using Glucosamine Sulphate and Methyl Salicylate on Pain and Hamstring Flexibility of Patients with Knee Osteoarthritis. Am J Health Res. 2014;2(5-1):40-44. doi: 10.11648/j.ajhr.s.2014020501.18
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Download@article{10.11648/j.ajhr.s.2014020501.18,
author = {Onigbinde Ayodele Teslim and Adesina Olawale Daniel and Tarimo Nesto and Ojoawo Adesola},
title = {Comparative Effects of a Single Treatment Session Using Glucosamine Sulphate and Methyl Salicylate on Pain and Hamstring Flexibility of Patients with Knee Osteoarthritis},
journal = {American Journal of Health Research},
volume = {2},
number = {5-1},
pages = {40-44},
doi = {10.11648/j.ajhr.s.2014020501.18},
url = {https://doi.org/10.11648/j.ajhr.s.2014020501.18},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajhr.s.2014020501.18},
abstract = {Transdermal delivery of topical medications is commonly used for managing osteoarthritis (OA). Osteoarthritis of the knee joint impairs lower limb functions which contributes to poor gait patterns. There is insufficient empirical data to support the efficacy of glucosamine sulphate and methyl salicilate cream in the management of knee OA. The aims of this study were to compare the immediate effects of glucosamine sulphate and methyl salicylate cream on pain, flexibility and knee flexion. Forty one subjects with grade ll knee OA were recruited for the study. They were randomly assigned to 2 groups. One gram of each topical formulation was administered to the knee joint using massage. Pre and post-intervention pain intensities, hamstring flexibilities and active knee flexion were measured. Descriptive, paired and independent t-tests statistics were used to analyze the data. There were significant reduction in pain intensities within the groups (t = 9.08, p<0.001; t =6.29, p<0.001). However, there was no significant difference in the post treatments pain intensities across the two groups. There were significant increase in the flexibilities of groups 1 and 2 post treatment (t= 9.14, p<0.001) and (t= -5.67, p<0.001) respectively but there was insignificant difference in the flexibilities of the groups. Similarly, there was insignificant difference in the range of motion when the active knee flexions of the two groups were compared. We concluded that transdermal massage of glucosamine was as effective as methyl salicilate in alleviating pains, improving hamstring flexibility and increasing knee flexion range of motion in a single treatment session among knee OA participants in this study.},
year = {2014}
}
TY - JOUR T1 - Comparative Effects of a Single Treatment Session Using Glucosamine Sulphate and Methyl Salicylate on Pain and Hamstring Flexibility of Patients with Knee Osteoarthritis AU - Onigbinde Ayodele Teslim AU - Adesina Olawale Daniel AU - Tarimo Nesto AU - Ojoawo Adesola Y1 - 2014/09/27 PY - 2014 N1 - https://doi.org/10.11648/j.ajhr.s.2014020501.18 DO - 10.11648/j.ajhr.s.2014020501.18 T2 - American Journal of Health Research JF - American Journal of Health Research JO - American Journal of Health Research SP - 40 EP - 44 PB - Science Publishing Group SN - 2330-8796 UR - https://doi.org/10.11648/j.ajhr.s.2014020501.18 AB - Transdermal delivery of topical medications is commonly used for managing osteoarthritis (OA). Osteoarthritis of the knee joint impairs lower limb functions which contributes to poor gait patterns. There is insufficient empirical data to support the efficacy of glucosamine sulphate and methyl salicilate cream in the management of knee OA. The aims of this study were to compare the immediate effects of glucosamine sulphate and methyl salicylate cream on pain, flexibility and knee flexion. Forty one subjects with grade ll knee OA were recruited for the study. They were randomly assigned to 2 groups. One gram of each topical formulation was administered to the knee joint using massage. Pre and post-intervention pain intensities, hamstring flexibilities and active knee flexion were measured. Descriptive, paired and independent t-tests statistics were used to analyze the data. There were significant reduction in pain intensities within the groups (t = 9.08, p<0.001; t =6.29, p<0.001). However, there was no significant difference in the post treatments pain intensities across the two groups. There were significant increase in the flexibilities of groups 1 and 2 post treatment (t= 9.14, p<0.001) and (t= -5.67, p<0.001) respectively but there was insignificant difference in the flexibilities of the groups. Similarly, there was insignificant difference in the range of motion when the active knee flexions of the two groups were compared. We concluded that transdermal massage of glucosamine was as effective as methyl salicilate in alleviating pains, improving hamstring flexibility and increasing knee flexion range of motion in a single treatment session among knee OA participants in this study. VL - 2 IS - 5-1 ER -
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