Sero-Prevalence of HIV and Syphilis Infection Among Pregnant Mothers Attended Labor Ward at Wolaita Sodo University Teaching Referral Hospital: A Five-Year Retrospective Study (2012-2016)
American Journal of Health Research
Volume 6, Issue 3, May 2018, Pages: 67-73
Received: Mar. 29, 2018; Accepted: May 31, 2018; Published: Aug. 14, 2018
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Temesgen Anjulo Ageru, Department of Medical Laboratory, Wolaita Sodo University Teaching and Referral Hospital, Wolaita Sodo, Ethiopia
Temesgen Lera Abiso, School of Public Health, College of Health Sciences and Medicine, Wolaita Sodo University, Wolaita Sodo, Ethiopia
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Sexually transmitted infections (STIs) such as HIV and Syphilis infections are the major public health problem in the developing countries. The prevalence of syphilis and HIV infections among pregnant women has been shown to vary by geographic areas, study population and time-period. Objective: The aim of study was to assess sero prevalence of HIV and syphilis and associated factors among pregnant women attended labor ward at Wolaita Sodo University Teaching and Referral Hospital. Method: Retrospective study was conducted using standard extraction format to assess the sero-prevalence of HIV and syphilis among pregnant women attending labor ward of WSTRH. Data were analyzed by using SPSS version 20.0 software and result was summarized using means and percentages and presented by using figure and tables. Descriptive statistics were used. Result: Overall prevalence of sexually transmitted infection among pregnant women in labor was 7.4% from these HIV sero-prevalence accounts for 3.8% and VDRL positivity enumerates to be 3.7%. HIV-syphilis co-infection was found to be 0.9%. Higher sero-prevalence of HIV, syphilis and co-infection rate was reported in 2016, among age category of 35-44 years. Conclusion and recommendation: Significant percentage of HIV, syphilis sero-prevalence and co-infection rate was found in this study with increased proportion in 2016. Strong antenatal screening and appropriate strategies should be devised for prevention and control of HIV, syphilis, in women of reproductive age.
HIV, Syphilis, Co-Infection, Sero-Prevalence, Pregnant Women
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Temesgen Anjulo Ageru, Temesgen Lera Abiso, Sero-Prevalence of HIV and Syphilis Infection Among Pregnant Mothers Attended Labor Ward at Wolaita Sodo University Teaching Referral Hospital: A Five-Year Retrospective Study (2012-2016), American Journal of Health Research. Vol. 6, No. 3, 2018, pp. 67-73. doi: 10.11648/j.ajhr.20180603.11
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Aron G, Laura B, Kelly C, Stephen K. Epidemiology of Sexually Transmitted Infections. Sex Trans Infectand Sex Transm Dis.2011; 13-23.
Frank N, Okonko I, Okerentugba P, Jaja N. Detection of HIV1/2 Antibodies among Pregnant Women in Port Harcourt, Rivers State, Nigeria. World Appl. Sci. J.2012; 16 (4): 589-598.
Khayota Grace N. Prevalence of HSV-2, syphilis and HBV in HIV-1 individuals in selected health facilities in Nairobi, Kenya [MSc Thesis]. Kenyatta University, Kenya. 2012; 1-67.
Okonko I, Anugweje K, Adeniji F, Abdulyekeen R. Syphilis, HIV, HCV and HBsAg co-infections among Sexually Active Adults. Nature and Science. 2012; 10(1):66-74.
Pennap G, Akpu P, Adoga M. Treponema pallidum Infection among a Cohort of Pregnant Women in North Central Nigeria. Ame J of Trop Med & Pub Health.2011; 1(2): 31-36.
World Health Organization (2003): Guideline for the Management of Sexually Transmitted Infections. Revised version. World Health Organization, Geneva, Switzerland.
Nicola M, Joseph E, Trevor P, Jeffrey D. Syphilis in the United States: An Update for Clinicians with an Emphasis on HIV Co-infection. Mayo Clin Proc. 2007; 82(9):1091-1102.
Sia E, Jacqueline U, Akhtar H, Elizabeth M, Stig J, Noel E et al. Prevalence of sexually transmitted infections among pregnant women with known HIV status in northern Tanzania. Reproductive Health.2009; 6(4):1-8.
Mulu A, Kassu A, Tessema B, Yismaw G, Tiruneh M, Moges F, et al. Sero-prevalence of syphilis and HIV-1 during pregnancy in a teaching hospital in northwest Ethiopia. Jpn J Infect Dis. 2007; 60:193–5.
Eticha BT, Sisay Z, Alemayehu A, Shimelis T. Seroprevalence of syphilis among HIV-infected individuals in Addis Ababa, Ethiopia: a hospital-based cross-sectional study. BMJ Open. 2013; 3:e002293. Doi: 10.1136/bmjopen-2013-002566.
Tessema B, Yismaw G, Kassu A, Amsalu A, Mulu A, Emmrich F, et al. Sero prevalence of HIV, HBV, HCV and syphilis infections among blood donors at Gondar University teaching hospital, northwest Ethiopia: declining trends over a period of five years. BMC Infect Dis. 2010; 10:111.9.
Zenebe Y, Mulu W, Yimer M, Abera B. Sero-prevalence and risk factors of hepatitis B virus and human immunodeficiency virus infection among pregnant women in Bahir Dar city, northwest Ethiopia: a cross sectional study. BMC Infect Dis. 2014; 14:118.
Buseri F, Seiyaboh E, Jeremiah Z. Surveying Infections among Pregnant Women in Niger Delta, Nigeria. J Glob Infect Dis.2010; 2(3):203-211.
Mulu A, Kassu A, Tessema B, et al. Seroprevalence of syphilis and HIV-1 during pregnancy in a teaching hospital in northwest Ethiopia. Jpn J Infect Dis. 2007 Jul; 60(4):193-5.
Global HIV/AIDS response. Epidemic update and health sector progress towards universal access. Geneva: World Health Organization; 2011. Available at: ( acquired-immune-deficiency syndrome/features/3439-global-hivaidsresponse-progress-report-2011.html.).
Gomez G, Kamb M, Newman L, Mark J, Broutet N, Hawkes S. Untreated maternal syphilis and adverse outcomes of pregnancy: a systematic review and meta-analysis. Bull World Health Organ. 2013; 91:217–26. doi:10.2471/BLT.12.107623.
World Health Organization. Global Elimination of Syphilis: rationale and strategy for action. Geneva, Switzerland; 2007.
Hawkes SJ, Gomez GB, Broutet N. Early antenatal care: does it make a difference to outcomes of pregnancy associated with syphilis? A systematic review and meta-analysis. PLoS-One. 2013; 8(2):e56713. Doi: 10.1371/journal. pone.0056713.
World Health Organization: regional office for Africa. Analytical summary, 2010. Available at: php/ Ethiopia.
Health Sector Development Programme IV. Annual performance report. Addis Ababa, Government of Ethiopia: Ministry of Health; 2010.
Ethiopian Health and Nutrition Research Institute. Report on the 2009 round antenatal care sentinel HIV surveillance in Ethiopia: Addis Ababa; 2011.
Qin J, Yang T, Xiao S, Tan H, Feng T, Fu H. Reported estimates of adverse pregnancy outcomes among women with and without syphilis: a systematic review and meta-analysis. PLoS One. 2014; 9(7):e102203.
Mwapasa V, Rogerson SJ, Kwiek JJ, et al. Maternal syphilis infection is associated with increased risk of mother-to-child transmission of HIV in Malawi. AIDS. 2006; 20(14):1869–1877.
World Health Organization. Women and Health: Today’s Evidence Tomorrow’s Agenda. Geneva: Gender: World Health Organization; 2009. Available from: MHI_STM.09.1_eng.pdf.
UNAIDS. Regional Fact Sheet 2012. Sub-Saharan Africa. Geneva: UNAIDS; 2012. Available from: files/en/media/unaids/contentassets/documents/epidemiology/2012/gr2012/2012_FS_regional_ssa_en.pdf
Kendall T, Danel I. Research and Evaluation Agenda for HIV and Maternal Health in sub-Saharan Africa: Women and Health Initiative Working Paper No 1. Boston, MA: Women and Health Initiative, Harvard School of Public Health; 2014.
Kebede B, Andargie A, Gebeyehu A. Birth outcome and correlates of low birth weight and preterm delivery among infants born to HIV-infected women in public hospitals of Northwest Ethiopia. Health. 2013; 5(7A4):25–34.
Zeleke BM, Zelalem M, Mohammed N. Incidence and correlates of low birth weight at a referral hospital in Northwest Ethiopia. Pan Afr Med J. 2012; 12:4.
Tricco AC, Antony J, Angeliki VA, et al. Safety and effectiveness of antiretroviral therapies for HIV-infected women and their infants and children: protocol for a systematic review and network meta-analysis. Syst Rev. 2014; 3:51.
World Health Organization. Baseline Report on Global Sexually Transmitted Infection Surveillance 2012. Geneva; World Health Organization; 2013.
Angelica M, Marta CA, Regina LN, Kelly RA, Anto N. Seroprevalence of HIV, HBV and Syphilis in Women at Their First Visit to Public Antenatal Clinics, Brazil. Sex Transm Dis. 2001; 28(12):710-713.
Tiruneh M. Seroprevalence of multiple sexually transmitted infections among antenatal clinic attendees in Gonder Health Center, Northwest Ethiopia. Ethiop Med J. 2008; 32(4):359-366.
C. J. Uneke, D. D, Duhlinska and E. B. Igbinedion. Prevalence and Public-health Significance of HIV Infection and Anaemia among Pregnant Women Attending Antenatal Clinics in South-eastern Nigeria J HEALTH POPUL NUTR, 25(3), 2008, 328-335.
Mbopi Kéou FX, Mbu R, Mauclère P, Andela A, Tetanye E, Léké R et al. Antenatal HIV prevalence in Yaounde, Cameroon. Int J STD AIDS. 1998; 9(7):400-4002.
L. E Abongwa, A. M Clara, NA. Edouard and N. H. Ngum. Sero-Prevalence of Human Immunodeficiency Virus (HIV) and Hepatitis B Virus (HBV) Co-Infection among Pregnant Women Residing in Bamenda Health District, Cameroon. Int. J. Curr. Microbiol. App. Sci (2015) 4(12): 473-483.
Yusuf K, Julius M, Raphael I, Julius M, Raphael I, John C et al. Trends in HIV & syphilis prevalence and correlates of HIV infection: results from cross-sectional surveys.
Robert L, Silvia M, Lee H, Renaldo I, Roberta B, Sonia B et al. Prevalence of Sexually Transmitted Diseases in Young Women Seeking HIV Testing in Rio de Janeiro, Brazil. Sex Transm Dis. 2004; 31(1): 67–72.
Thu-Ha D, Mary L, Veerle M. Integration of Preventing Mother-To-Child Transmission of HIV and Syphilis Testing and Treatment in Antenatal Care Services in the Northern Cape and Gauteng Provinces, South Africa. Sex Transm Dis. 2013; 40(11):846-850.
Federal Ministry of Heath/Ethiopian Health and Nutrition Research Institute. Report on the 2009 Round Antenatal Care Sentinel HIV Surveillance in Ethiopia. Addis Ababa, Ethiopia; 2011.
Henok S. Prevalence of HIV among antenatal care attendants at Kazanchis Health center in the last five years (2006-2010), Addis Ababa, Ethiopia. [MSc Thesis]. Addis Ababa University, Ethiopia. 2011; 1-38.
Tiruneh M. Seroprevalence of multiple sexually transmitted infections among antenatal clinic attendees in Gonder Health Center, Northwest Ethiopia. Ethiop Med J. 2008; 46(4):359-366.
Endris M, Deressa D, Belyhun Y and Moges F. Seroprevalence of syphilis and human immunodeficiency virus infections among pregnant women who attend the University of Gondar teaching hospital, Northwest Ethiopia: a cross sectional study. BMC Infectious Diseases (2015) 15:111.
Melku M. Kebede A, Addis Z. Magnitude of HIV and syphilis Seroprevalence among pregnant women in Gondar, northwest Ethiopia: a cross-sectional study. HIV/AIDS – Research and Palliative Care 2015:7: 175–182
Krunal D. Mehta, Sejul Antala, Madhulika Mistry, Yogesh Goswami. Seropositivity of hepatitis B, hepatitis C, syphilis, and HIV in antenatal women in India. J Infect Dev Ctries 2013; 7(11):832-837.
José M, Sofia B, Francisco R, Juan C, Gloria R, Félix G. Seroprevalence of HIV-1, HBV, HTLV-1 and T. pallidum infections among pregnant women in a rural hospital in Southern Ethiopia. Journal of clinical virology.2011; 51(1):83-85.
Kuznik A, Lamorde M, Nyabigambo A, Manabe YC. Antenatal syphilis screening using point-of-care testing in sub-Saharan African countries: a cost-effectiveness analysis. PLoS Med. 2013; 10(11):e1001545. doi:10.1371/journal.pmed.1001545.
Frickmann H, Schwarz NG, Girmann M, et al. Serological survey of HIV and syphilis in pregnant women in Madagascar. Trop Med Int Health. 2013; 18(1):35–39.
Nessa A, Islam MN, Ashraf F, et al. Seroprevalence of Treponema Pallidum antibody among pregnant population of Bangladesh. J Obstet Gynaecol Res. 2011; 37(11):1625–1630.
Kebede E and Chamiso B. Prevalence of syphilis in pregnancy in Addis Ababa. East African Medical Journal. 2000; 77(4):212-215.
Yahya-Malima KI, Evjen-Olsen B, Matee MI, Fylkesnes K, Haarr L. HIV-1, HSV-2 and syphilis among pregnant women in a rural area of Tanzania: prevalence and risk factors. BMC Infect Dis. 2008; 8:75.
Azeze B, Fantahun M, Kidan KG, Haile T. Seroprevalence of syphilis amongst pregnant women attending antenatal clinics in a rural hospital in north west Ethiopia. Genitourin Med. 1995; 71(6):347–350.
Ojo DA, Oyetunji IAO. Sero-prevalence of syphilis among pregnant women In Osogbo in Southwestern Nigeria. ASSET Series B. 2007; 6(1): 61–65.
Omisakin CT, Esan AJ, Fasskin KA Syphilis and HIV co-infection among pregnant women in Nigeria: Prevalence and trend. ISRR 2014(2):95-100.
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