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Diagnosis of E.ewingii is usually based on observation of its morula in the granulocytes. A.phagocytophilum inclusions are observed in neutrophils. Different species of hemotropic Mycoplasma are observed as dot, rod and rarely chain on reticulocyte surface. Some serological and molecular tests are also available.
In this research, E.ewingii/A.phagocytophilum and hemotropic Mycoplasma spp. were observed in different previously taken blood films of dogs which had been referred to different veterinary hospitals of Tehran. There were also some abnormalities in leukocyte count of infected dogs.
In those cases, the sera and whole blood samples were not available. Therefore, the accurate infective pathogen which was observed in neutrophils was recorded as E.ewingii/A.phagocytophilum.
All of these three reported pathogens can be treated by tetracycline and tetracycline derivatives.
All of them also have zoonotic importance.
*Maryam Rassouli, Pathobiology department of 1- Shahmirzad School of Veterinary Medicine, 2- Faculty of Veterinary Medicine, Semnan University, Semnan, Iran.
**Ghazale Aghazamani, Shahmirzad School of Veterinary Medicine, Semnan University, Semnan, Iran.
An article will be published by Animal and Veterinary Sciences, Science Publishing Group, 2015.