Type 2 diabetes is a metabolic disorder characterized by hyperglycemia, developing insulin resistance, β-cell dysfunction and impaired insulin secretion. Several multiple metabolic disorders including impaired lipid and lipoprotein metabolism, oxidative stress, sub-clinical inflammation, vascular endothelial dysfunction and hypertension have commonly been accompanied with type 2 diabetes; these metabolic disorders lead to long-term pathogenic conditions such as micro- and macro-vascular complications including neuropathy, retinopathy, nephropathy, and a decreased quality of life and an increased mortality rate.
Despite availability of multiple pharmacological interventions including oral hypoglycemic agents and insulin therapy for diabetes management, current evidence shows an alarming trend in the occurrence of undesirable complications in the patients.
During the past two decades, the concept of functional food has been developed; functional foods beyond the basic nutritional functions have potential benefits to promote health and reduce the risk of chronic diseases and therefore they have greatly been considered. In recent years, researchers have focused on properties of functional foods bioactive compounds in control of various aspects of diabetes mellitus. Considering the multiple biological properties of functional foods and its bioactive compounds, application of these foods as a supplement in type 2 diabetic patients, is one of the interests of researchers.
The proposed special issue "Functional Foods and Nutraceuticals for Management of Type 2 Diabetes" could be contain research articles as well as review articles.