Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Assiut University
Alyaa Hatem Mohamed Salim
Pharmcogonsy Department, Sohag University
Ahmed Ibrahim Hassan
Pharmaceutical Chemistry, El Azhar University
In recent years, spectroscopic techniques have come to be regarded as attractive and promising analytical tools for analyses conducted in research, control or industrial laboratories. These techniques are increasingly considered by analysts as an obvious solution. This trend stems from instrumental developments, the extensive use of computers and the development of appropriate chemometric procedures. Daily, new applications of spectroscopic techniques in the fields of chemistry, drugs, the agro-food sector, life sciences and environmental analysis are being demonstrated and published. The objective should be not only to extend the field of application of spectroscopic techniques, but also to use them as a matter of course in control and industrial laboratories and to develop (according to internationally accepted guidelines) fully validated spectroscopic methods. Spectroscopy is considered very important in drug analysis as most of the spectroscopic techniques are simple rapid, cheap and available in most laboratories. These advantages make spectroscopic techniques superior in quality control laboratories. Spectroflourimetry gains high sensitivity which enables the determination of drugs in several biological fluids either by utilizing the native fluorescence of the fluorescent drugs or using flourogenic devitalizing reagent. FT-NIR measurements extremely accurate and reproducible. Thus, it is a very reliable technique for the positive identification and quantitation of any sample.