International Journal of Pharmacy and Chemistry

Special Issue

Analysis and Removal of Genotoxic Impurities in Pharmaceutical Compounds

  • Submission Deadline: 30 May 2017
  • Status: Submission Closed
  • Lead Guest Editor: Göksel Arli
About This Special Issue
The presence of chemicals also called impurities in pharmaceutical compounds may effect the efficiency and reliability of the final product. Especially, trace amount of genotoxic impurities in the pharmaceutical compounds play a crucial role in human mutagenicity and carcinogenicity. Considering this matter, either pharma industry or regulatory authorities have carefully focused on this issue. In 2007, a genotoxic compound ethyl mesylate was determined in some batches of Viracept which is an antiviral drug used for the treatment of AIDS produced by Roche. Thereupon, EU has suspended the licence of the drug and drug has been recalled. After this incident, research on the determination and removal of genotoxic impurities has rapidly increased.
This special issue aims to provide a comprehensive collection of original research articles on the analysis and removal of genotoxic impurities in pharmaceutical compounds.

Aims and Scope:
Development of analytical methods for the analysis of genotoxic impurities
Design and preparation of new materials for the removal of genotoxic impurities
Purification of pharmaceutical compounds
Application of polymers in genotoxic impurity removal
Application of reactive scavengers in genotoxic impurity removal
Lead Guest Editor
  • Göksel Arli

    Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey

Guest Editors
  • Rüstem Keçili

    Department of Medical Services and Techniques/Yunus Emre Vocational School, Anadolu University, Eskişehir, Turkey

  • Murat Soyseven

    Department of Medical Services and Techniques/Yunus Emre Vocational School, Anadolu University, Eskişehir, Turkey