School of Psychology, Aristotle University of Thessaloniki,
The complicated link between the brain and the heart can be mapped out from the complex of higher nervous system influences descending down to the heart. This complex innervates key autonomic structures from the brain's cortex to the heart along the neurocardiac axis. The heart is both the source of life and a source of cardiac arrhythmias and complications. The information originates in the brain's cortex and descends down to the hypothalamus. The neural signals are then transferred to the brainstem, followed by the spinal cord, which is the location where the heart receives all its signals from. In further detail, the heart receives its neural input through parasympathetic and sympathetic ganglia and lateral grey column of the spinal cord. The cardiovascular system is regulated by the autonomic nervous system, which includes the sympathetic and parasympathetic nervous systems. A distinct balance between these systems is crucial for the pathophysiology of cardiovascular disease. An imbalance can be caused by hormone levels, lifestyle, environmental stressors, and injuries. The effects of stress on the heart are studied in terms of the heart's interactions with both the peripheral nervous system and the central nervous system. Keeping in mind the above, we consider that heart and brain have a dynamic relationship that includes a lot of diseases and having a strong connection with each other. This special issue would include topics that are referred to this dynamic relationship.