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The Effect of BCAA Supplementation in Aiding Muscle Soreness to Prevent Lateral Ligament Ankle Injuries in Basketball

Ankle injuries are very common in basketball, with 45% of basketball players experiencing at least one sprain at any point in their career and 53.7% of missed playtime is caused by ankle injuries. These injuries can be caused by overworking muscles and causing them to reach maximum tension and soreness. When this happens, the surrounding ligaments and tendons are more susceptible to injury since the muscles that they hold together are weaker and don't function at full strength. The purpose of the study is to understand if athletes will benefit from taking supplements of Branched Chain Amino Acid (BCAA), to prevent ankle injuries from high a vertical mobility sport like basketball, which includes vertical jumps, layups and re-bounds. Using a combination data collected from control group vs placebo group we proved that BCAA reduces muscle soreness. This is proved by lower soreness scores, and lower values of Creatine kinase (CK) in the blood by the control group that took BCAA. We then proved there is a direct linkage between soreness and muscle fatigue by referring to a study conducted on lateral muscle of Rabbits, which show muscle fatigue, cause soreness and resulting in lower energy production and instability in function, leading to Injury. Based on the study, we comprehensively conclude that BCAA can help reduce risk of ankle injury by reducing muscle soreness and fatigue in basketball players, thereby promoting stable lateral and ankle dorsiflexor muscles.

Sports Medicine, Basketball Injury, Ankle Sprain, Athletic Injuries

Rakshith Srinivasan. (2023). The Effect of BCAA Supplementation in Aiding Muscle Soreness to Prevent Lateral Ligament Ankle Injuries in Basketball. American Journal of Sports Science, 11(1), 20-25.

Copyright © 2023 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License ( which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

1. Trisha A. Van Dusseldorp, Kurt A. Escobar, Kelly E. Johnson, Matthew T. Stratton, Terence Moriarty, Nathan Cole, James J. McCormick, Chad M. Kerksick, Roger A. Vaughan, Karol Dokladny, Len Kravitz, and Christine M. Mermier, Effect of Branched-Chain Amino Acid Supplementation on Recovery Following Acute Eccentric Exercise, National Library of Medicine, University of New Mexico Research Allocations Committee, 2018 Oct 1. doi: 10.3390/nu10101389, Online.
2. Michael V Fedewa, Steven O Spencer, Tyler D Williams, Zachery E Becker, Collin A Fuqua, Effect of branched-Chain Amino Acid Supplementation on Muscle Soreness following Exercise: A Meta-Analysis, National Library of Medicine, University of Alabama, Samford University, 2019 Apr 2, DOI: 10.1024/0300-9831/a000543, Online.
3. Martim Gomes Weber, Silas Seolin Dias, Tarlyson Regioli de Angelis, Eduardo Vignoto Fernandes, Andrea Gomes Bernardes, Vinicius Flavio Milanez, Eduardo Inocente Jussiani, Solange de Paula Ramos, The use of BCAA to decrease delayed-onset muscle soreness after a single bout of exercise: a systematic review and meta-analysis, PubMed, Grant Support Conselho Nacional de Pesquisa e Desenvolvimento tecnológico, 2021 Oct 20, DOI: 10.1007/s00726-021-03089-2.
4. Yoshiharu Shimomura, Asami Inaguma, Satoko Watanabe, Yuko Yamamoto, Yuji Muramatsu, Gustavo Bajotto, Juichi Sato, Noriko Shimomura, Hisamine Kobayashi and Kazunori Mawatari, Branched-Chain Amino Acid Supplementation Before Squat Exercise and Delayed-Onset Muscle Soreness, Human Kinetics Journal, Nagoya University Hospital, DOI:
5. Westerblad, H., Bruton, J., Allen, D. et al. “Functional significance of Ca2+ in long-lasting fatigue of skeletal muscle”. Eur J Appl Physiol 83, 166–174 (2000).
6. Song-Gyu Ra, Keisuke Ishikura, Hisashi Nagayama, Shoichi Komine, Yoshio Nakata, Seiji Maeda, Yasushi Matsuzaki, Hajime Ohmori, Combined effect of branched-chain amino acids and taurine supplementation on delayed onset muscle soreness and muscle damage in high-intensity eccentric exercise, Journal of the International Society of Sports Nutritio, Apl 1, 2022, DOI:
7. S D Mair, A V Seaber, R R Glisson, W E Garrett Jr, “The role of fatigue in susceptibility to acute muscle strain injury”, National Library of Medicine,, Department of Surgery, Duke University Medical Center, Apl 24 1996, DOI: 10.1177/036354659602400203.
8. Katy McLaughlin, Ph.D, Anaerobic Respiration, Editors. "Anaerobic Respiration." Biology Dictionary,, 27 Oct. 2016,
9. Osr physical therapy, “What Is Muscle Imbalance?”, OSR Physical Therapy, July 06, 2018, Online,
10. K Matsumoto, K Matsumoto, T Koba, K Hamada, M Sakurai, T Higuchi, Hirofumi Miyata, Branched-chain amino acid supplementation attenuates muscle soreness, muscle damage and inflammation during an intensive training program, The Journal of sports medicine and physical fitness, December 2009, 49 (4): 424-31, Research Gate, Online.
11. Gregory Minnis, Jessica Caporuscio, What to know about muscle fatigue, Medical News Today.
12. Pfizer, “Science Fact or Science Fiction? Lactic Acid Buildup Causes Muscle Fatigue and Soreness”, Https://, Jan 20022, Pfizer.
13. Claudia R da Luz, Humberto Nicastro, Nelo E Zanchi, Daniela FS Chaves, “Potential therapeutic effects of branched-chain amino acids supplementation on resistance exercise-based muscle damage in humans”, NIS, Aug 2022, NIS, Online.
14. Prosups, “How Much BCAA Do You Need In A Day?”, Online,
15. BMC, “Exercise-induced muscle damage is reduced in resistance-trained males by branched chain amino acids: a randomized, double-blind, placebo controlled study”, / May 212. Journal of the International Society of Sports Nutrition.