Purpose: Severe visual sequelae can be frequently observed in patients with diabetic tractional retinal detachment (TRD) involving the macula. We analyzed the postoperative structural spectral-domain (SD)-OCT and optical coherent tomography angiography (OCT angiography) findings in four selected eyes that were enrolled after successful anatomical diabetic macular detachment repair. These diabetic macular tractional detachments were evolved within 16 weeks. We also correlated the postoperative mean best-corrected visual acuity with the postoperative SD-OCT and OCT angiographic findings. Methods: This case series included 4 selected eyes of 4 patients with a mean diabetes evolution period of 18.4±4.8 years SD. Vitrectomy techniques were successfully used for TRD involving the macula. Postoperative SD-OCT, and final postoperative functional evaluations, including BCVA and OCT angiographic evaluation were performed at the final postoperative follow-up visit. Results: The mean difference between the preoperative (0.87±0.15) and final postoperative (0.35±0.21) BCVA was significant (p<0.05). The mean duration of vision loss before surgery was 11.6±2.3 weeks. The mean time for postoperative macular detachment resolution was 3.6±1.7 weeks SD. A mean follow-up evaluation of 13.1±2.7 SD months. Final postoperative imaging tests demonstrated multiple abnormalities of the foveal avascular zone and different areas of non-perfused macula on OCT angiography. The presence of disorganization of the retinal inner layers (DRIL) and chronic ischemic macular edema changes in 3 eyes (75.0%) as well as the OCT angiography abnormal findings in 3 (75.0%) were analized and correlated. Conclusion: In successfully reattached macula, postoperative microcirculatory abnormalities consistent with superficial and deep plexuses deficiencies and vessel densities alterations were detected as well as persistent DRIL, EZ and ELM line abnormalities.
| Published in | International Journal of Ophthalmology & Visual Science (Volume 6, Issue 4) |
| DOI | 10.11648/j.ijovs.20210604.12 |
| Page(s) | 187-198 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Disorganization of the Retinal Inner Layers, Ellipsoid Zone, External Limiting Membrane, Optical Coherent Tomography Angiography, Proliferative Diabetic Retinopathy, Tractional Retinal Detachment
| [1] | Cruz-Iñigo YJ, Acabá LA, Berrocal MH. Surgical management of retinal diseases: proliferative diabetic retinopathy and traction retinal detachment. Dev Ophthalmol. 2014; 54: 196–203. |
| [2] | Sharma S, Hariprasad SM, Mahmoud TH. Surgical management of proliferative diabetic retinopathy. Ophthal Surg Lasers Imaging Retina. 2014; 45: 188–93. |
| [3] | Centers for Disease Control and Prevention (CDC). Blindness caused by diabetes--Massachusetts, 1987–1994. MMWR Morb Mortal Wkly Rep. 1996; 45: 937–41. |
| [4] | Barzideh N, Johnson TM. Subfoveal fluid resolves slowly after pars plana vitrectomy for tractional retinal detachment secondary to proliferative diabetic retinopathy. Retina. 2007; 27: 740–3. |
| [5] | Writing Committee for the Diabetic Retinopathy Clinical Research Network, Gross JG, Glassman AR, Jampol LM, Inusah S, Aiello LP et al. JAMA. 2015; 314: 2137–46. |
| [6] | Sivaprasad S, Prevost AT, Vasconcelos JC, Riddell A, Murphy C, Kelly J, et al. Clinical efficacy of intravitreal aflibercept versus panretinal photocoagulation for best corrected visual acuity in patients with proliferative diabetic retinopathy at 52 weeks (CLARITY): a multicentre, single-blinded, randomised, controlled, phase 2b, non-inferiority trial. Lancet. 2017; 389: 2193–203. |
| [7] | Mikhail M, Ali-Ridha A, Chorfi S, Kapusta MA. Long-term outcomes of sutureless 25-G+ pars-plana vitrectomy for the management of diabetic tractional retinal detachment. Graefes Arch Clin Exp Ophthalmol. 2017; 255: 255–61. |
| [8] | Sun JK, Lin MM, Lammer J, Prager S, Sarangi R, Silva PS, et al. Disorganization of the retinal inner layers as a predictor of visual acuity in eyes with center-involved diabetic macular edema. JAMA Ophthalmol. 2014; 132: 1309–16. |
| [9] | Sun JK, Radwan SH, Soliman AZ, Lammer J, Lin MM, Prager SG, et al. Neural retinal disorganization as a robust marker of visual acuity in current and resolved diabetic macular edema. Diabetes. 2015; 64: 2560–70. |
| [10] | Gorczynska I, Migacz JV, Zawadzki RJ, Capps AG, Werner JS. Comparison of amplitude-decorrelation, speckle-variance and phase-variance OCT angiography methods for imaging the human retina and choroid. Biomed Opt Express. 2016; 7: 911–42. |
| [11] | Dugel PU. Retina care is ready for OCT angiography. Retinal Physician eUpdate. [cited 26 Mar 2019] Retrieved from: https://www.retinalphysician.com/newsletter/oct-angiography-eupdate/april-2015 |
| [12] | Baumal CR. Practical Pearls for octa image interpretation. Become familiar with common challenges to overcome pitfalls. Retin Phys. 2018; 15: 32–4. |
| [13] | Gill A, Cole ED, Novais EA, Louzada RN, de Carlo T, Duker JS, et al. Visualization of changes in the foveal avascular zone in both observed and treated diabetic macular edema using optical coherence tomography angiography. Int J Retina Vitr. 2017; 3: 19. |
| [14] | Yannuzzi LA, Rohrer KT, Tindel LJ, Sobel RS, Costanza MA, Shields W, et al. Fluorescein angiography complication survey. Ophthalmology. 1986; 93: 611–7. |
| [15] | Ho AC, Yannuzzi LA, Guyer DR, Slakter JS, Sorenson JA, Orlock DA. Intraretinal leakage of indocyanine green dye. Ophthalmology. 1994; 101: 534–41. |
| [16] | Hwang TS, Zhang M, Bhavsar K, Zhang X, Campbell JP, Lin P, et al. Visualization of 3 distinct retinal plexuses by projection-resolved optical coherence tomography angiography in diabetic retinopathy. JAMA Ophthalmol. 2016; 134: 1411–9. |
| [17] | Spaide RF, Klancnik JM, Cooney MJ, Yannuzzi LA, Balaratnasingam C, Dansingani KK, et al. Volume-rendering optical coherence tomography angiography of macular telangiectasia type 2. Ophthalmology. 2015; 122: 2261–9. |
| [18] | Spaide RF, Klancnik JM, Cooney MJ. Retinal vascular layers imaged by fluorescein angiography and optical coherence tomography angiography. JAMA Ophthalmol. 2015; 133: 45–50. |
| [19] | Matsunaga D, Yi J, Puliafito CA, Kashani AH. OCT angiography in healthy human subjects. Ophthal Surg Lasers Imaging Retina. 2014; 45: 510–5. |
| [20] | Tan PEZ, Balaratnasingam C, Xu J, Mammo Z, Han SX, Mackenzie P, et al. Quantitative comparison of retinal capillary images derived by speckle variance optical coherence tomography with histology. Investig Ophthalmol Vis Sci. 2015; 56: 3989–96. |
| [21] | OHSU. Study shows new technology may improve management of leading causes of blindness. Portland, OR: Oregon Health & Science University; 2015. |
| [22] | Kwiterovich KA, Maguire MG, Murphy RP, Schachat AP, Bressler NM, Bressler SB, et al. Frequency of adverse systemic reactions after fluorescein angiography. Results of a prospective study. Ophthalmology. 1991; 98: 1139–42. |
| [23] | Diabetic Retinopathy Clinical Research Network. Randomized clinical trial evaluating intravitreal ranibizumab or saline for vitreous hemorrhage from proliferative diabetic retinopathy. JAMA Ophthalmol. 2013; 131: 283–93. |
| [24] | Bhavsar AR, Torres K, Glassman AR, Jampol LM, Kinyoun JL, Diabetic Retinopathy Clinical Research Network. Evaluation of results 1 year following short-term use of ranibizumab for vitreous hemorrhage due to proliferative diabetic retinopathy. JAMA Ophthalmol. 2014; 132: 889–90. |
| [25] | de Carlo TE, Bonini Filho MAB, Baumal CR, Reichel E, Rogers A, Witkin AJ, et al. Evaluation of preretinal neovascularization in proliferative diabetic retinopathy using optical coherence tomography angiography. Ophthal Surg Lasers Imaging Retina. 2016; 47: 115–9. |
| [26] | Matsunaga DR, Yi JJ, De Koo LO, Ameri H, Puliafito CA, Kashani AH. Optical coherence tomography angiography of diabetic retinopathy in human subjects. Ophthal Surg Lasers Imaging Retina. 2015; 46: 796–805. |
| [27] | Ishibazawa A, Nagaoka T, Takahashi A, Omae T, Tani T, Sogawa K, et al. Optical coherence tomography angiography in diabetic retinopathy: a prospective pilot study. Am J Ophthalmol. 2015; 160: 35–44. e1. |
| [28] | Moein HR, Novais EA, Rebhun CB, Cole ED, Louzada RN, Witkin AJ, et al. Optical coherence tomography angiography to detect macular capillary ischemia in patients withs inner retinal changes after resolved diabetic macular edema. Retina. 2017; 38: 2277–84. |
| [29] | Mendis KR, Balaratnasingam C, Yu P, Barry CJ, McAllister IL, Cringle SJ, et al. Correlation of histologic and clinical images to determine the diagnostic value of fluorescein angiography for studying retinal capillary detail. Investig Ophthalmol Vis Sci. 2010; 51: 5864–69. |
| [30] | Samara WA, Shahlaee A, Adam MK, Khan MA, Chiang A, Maguire JI, et al. Quantification of diabetic macular ischemia using optical coherence tomography angiography and its relationship with visual acuity. Ophthalmology. 2017; 124: 235–44. |
| [31] | Hsieh YT, Alam MN, Le D, Hsiao CC, Yang CH, Chao DL, et al. OCT angiography biomarkers for predicting visual outcomes after ranibizumab treatment for diabetic macular edema. Ophthalmol Retina. 2019; 3: 826–34. |
| [32] | Freiberg FJ, Pfau M, Wons J, Wirth MA, Becker MD, Michels S. Optical coherence tomography angiography of the foveal avascular zone in diabetic retinopathy. Graefes Arch Clin Exp Ophthalmol. 2016; 254: 1051–8. |
| [33] | Hwang TS, Gao SS, Liu L, Lauer AK, Bailey ST, Flaxel CJ, et al. Automated quantification of capillary nonperfusion using optical coherence tomography angiography in diabetic retinopathy. JAMA Ophthalmol. 2016; 134: 367–73. |
| [34] | Ishibashi T, Sakimoto S, Shiraki N, Nishida K, Sakaguchi H, Nishida K. Association between disorganization of retinal inner layers and visual acuity after proliferative diabetic retinopathy surgery [sci. rep.: 12230]. Sci Rep. 2019; 9: 12230. |
| [35] | Shin HJ, Lee SH, Chung H, Kim HC. Association between photoreceptor integrity and visual outcome in diabetic macular edema. Graefes Arch Clin Exp Ophthalmol. 2012; 250: 61–70. |
| [36] | Durbin MK, An L, Shemonski ND, Soares M, Santos T, Lopes M, et al. Quantification of retinal microvascular density in optical coherence tomographic angiography images in diabetic retinopathy. JAMA Ophthalmol. 2017; 135: 370–6. |
APA Style
Miguel Angel Quiroz-Reyes, Erick Andres Quiroz-Gonzalez, Felipe Esparza-Correa, Jennifer Hyuna Kim-Lee, Alejandra Nieto-Jordan, et al. (2021). Structural and Perfusional Study of Successfully Repaired Diabetic Tractional Retinal Detachment Involving the Macula. International Journal of Ophthalmology & Visual Science, 6(4), 187-198. https://doi.org/10.11648/j.ijovs.20210604.12
ACS Style
Miguel Angel Quiroz-Reyes; Erick Andres Quiroz-Gonzalez; Felipe Esparza-Correa; Jennifer Hyuna Kim-Lee; Alejandra Nieto-Jordan, et al. Structural and Perfusional Study of Successfully Repaired Diabetic Tractional Retinal Detachment Involving the Macula. Int. J. Ophthalmol. Vis. Sci. 2021, 6(4), 187-198. doi: 10.11648/j.ijovs.20210604.12
AMA Style
Miguel Angel Quiroz-Reyes, Erick Andres Quiroz-Gonzalez, Felipe Esparza-Correa, Jennifer Hyuna Kim-Lee, Alejandra Nieto-Jordan, et al. Structural and Perfusional Study of Successfully Repaired Diabetic Tractional Retinal Detachment Involving the Macula. Int J Ophthalmol Vis Sci. 2021;6(4):187-198. doi: 10.11648/j.ijovs.20210604.12
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Download@article{10.11648/j.ijovs.20210604.12,
author = {Miguel Angel Quiroz-Reyes and Erick Andres Quiroz-Gonzalez and Felipe Esparza-Correa and Jennifer Hyuna Kim-Lee and Alejandra Nieto-Jordan and Boris Moreno-Andrade and Jorge Morales-Navarro and Federico Graue-Wiechers},
title = {Structural and Perfusional Study of Successfully Repaired Diabetic Tractional Retinal Detachment Involving the Macula},
journal = {International Journal of Ophthalmology & Visual Science},
volume = {6},
number = {4},
pages = {187-198},
doi = {10.11648/j.ijovs.20210604.12},
url = {https://doi.org/10.11648/j.ijovs.20210604.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijovs.20210604.12},
abstract = {Purpose: Severe visual sequelae can be frequently observed in patients with diabetic tractional retinal detachment (TRD) involving the macula. We analyzed the postoperative structural spectral-domain (SD)-OCT and optical coherent tomography angiography (OCT angiography) findings in four selected eyes that were enrolled after successful anatomical diabetic macular detachment repair. These diabetic macular tractional detachments were evolved within 16 weeks. We also correlated the postoperative mean best-corrected visual acuity with the postoperative SD-OCT and OCT angiographic findings. Methods: This case series included 4 selected eyes of 4 patients with a mean diabetes evolution period of 18.4±4.8 years SD. Vitrectomy techniques were successfully used for TRD involving the macula. Postoperative SD-OCT, and final postoperative functional evaluations, including BCVA and OCT angiographic evaluation were performed at the final postoperative follow-up visit. Results: The mean difference between the preoperative (0.87±0.15) and final postoperative (0.35±0.21) BCVA was significant (pConclusion: In successfully reattached macula, postoperative microcirculatory abnormalities consistent with superficial and deep plexuses deficiencies and vessel densities alterations were detected as well as persistent DRIL, EZ and ELM line abnormalities.},
year = {2021}
}
TY - JOUR T1 - Structural and Perfusional Study of Successfully Repaired Diabetic Tractional Retinal Detachment Involving the Macula AU - Miguel Angel Quiroz-Reyes AU - Erick Andres Quiroz-Gonzalez AU - Felipe Esparza-Correa AU - Jennifer Hyuna Kim-Lee AU - Alejandra Nieto-Jordan AU - Boris Moreno-Andrade AU - Jorge Morales-Navarro AU - Federico Graue-Wiechers Y1 - 2021/10/15 PY - 2021 N1 - https://doi.org/10.11648/j.ijovs.20210604.12 DO - 10.11648/j.ijovs.20210604.12 T2 - International Journal of Ophthalmology & Visual Science JF - International Journal of Ophthalmology & Visual Science JO - International Journal of Ophthalmology & Visual Science SP - 187 EP - 198 PB - Science Publishing Group SN - 2637-3858 UR - https://doi.org/10.11648/j.ijovs.20210604.12 AB - Purpose: Severe visual sequelae can be frequently observed in patients with diabetic tractional retinal detachment (TRD) involving the macula. We analyzed the postoperative structural spectral-domain (SD)-OCT and optical coherent tomography angiography (OCT angiography) findings in four selected eyes that were enrolled after successful anatomical diabetic macular detachment repair. These diabetic macular tractional detachments were evolved within 16 weeks. We also correlated the postoperative mean best-corrected visual acuity with the postoperative SD-OCT and OCT angiographic findings. Methods: This case series included 4 selected eyes of 4 patients with a mean diabetes evolution period of 18.4±4.8 years SD. Vitrectomy techniques were successfully used for TRD involving the macula. Postoperative SD-OCT, and final postoperative functional evaluations, including BCVA and OCT angiographic evaluation were performed at the final postoperative follow-up visit. Results: The mean difference between the preoperative (0.87±0.15) and final postoperative (0.35±0.21) BCVA was significant (pConclusion: In successfully reattached macula, postoperative microcirculatory abnormalities consistent with superficial and deep plexuses deficiencies and vessel densities alterations were detected as well as persistent DRIL, EZ and ELM line abnormalities. VL - 6 IS - 4 ER -
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