International Journal of Infectious Diseases and Therapy

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Serodiagnosis of Hepatitis B Virus Infection among Jessu Community of Gombe State, Nigeria

Received: 08 August 2018    Accepted: 24 August 2018    Published: 17 September 2018
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Abstract

Hepatitis B virus causes disease of the liver and is a global health problem that leads to liver cirrhosis and hepatocellular carcinoma. Despite the dangers posed by this silent and deadly disease, there is little or no documented work on Hepatitis B infections in Jessu community, Gombe State, North East Nigeria. This study was undertaken to determine the sero-prevalence of Hepatitis B Virus infection and possible risk factors associated with the transmission of HBV. Blood samples (3ml) were collected from 196 eligible consented subjects and the serum samples were tested for the presence of HBsAg using On Site HBsAg Rapid Test Kit manufactured by CTK Biotech, USA. The OnSite HBV 5-Parameter Rapid Test also manufactured by CTK Biotech, USA was used to confirm those that were positive. Of the 196 eligible subjects examined, 5.6% were confirmed positive for HBsAg, 8.6% were males and 2.9% were females. Age distribution of HBsAg among the population shows the highest seroprevalence of 8.9% HBsAg in ages 16-30 years, followed by 4.5% in ages 31-45 years while ages 0-15 years had 3.5% seroprevalence. Participants who share sharp objects recorded the highest prevalence of 6.3% HCV infection followed by blood transfusion with 5.9% prevalence and those with multiple sex partners had the least prevalence of 1.8% HCV infection. The seroprevalence of 5.6% HBV in this study indicated the presence of HBV in Jessu Community in Gombe State, North East Nigeria.

DOI 10.11648/j.ijidt.20180302.14
Published in International Journal of Infectious Diseases and Therapy (Volume 3, Issue 2, June 2018)
Page(s) 40-44
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Hepatitis, HBV, Hepatocytes, Hepatocellular Carcinoma, HBsAg, OnSite HBV 5-Parameter Rapid Test

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Author Information
  • Department of Medical Laboratory Science, University of Jos, Jos, Nigeria; School of Medicine and Allied Health Sciences, University of the Gambia, Banjul, Gambia

  • Department of Medical Laboratory Science, University of Jos, Jos, Nigeria

  • Department of Medical Laboratory Science, University of Jos, Jos, Nigeria

  • Department of Medical Laboratory Science, University of Jos, Jos, Nigeria

  • Department of Medical Laboratory Science, University of Jos, Jos, Nigeria

Cite This Article
  • APA Style

    Sheyin Zakka, Frama Ishaku, Essien Unyime Cosmas, Shindang John, Bigwan Emmanuel Isa. (2018). Serodiagnosis of Hepatitis B Virus Infection among Jessu Community of Gombe State, Nigeria. International Journal of Infectious Diseases and Therapy, 3(2), 40-44. https://doi.org/10.11648/j.ijidt.20180302.14

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    ACS Style

    Sheyin Zakka; Frama Ishaku; Essien Unyime Cosmas; Shindang John; Bigwan Emmanuel Isa. Serodiagnosis of Hepatitis B Virus Infection among Jessu Community of Gombe State, Nigeria. Int. J. Infect. Dis. Ther. 2018, 3(2), 40-44. doi: 10.11648/j.ijidt.20180302.14

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    AMA Style

    Sheyin Zakka, Frama Ishaku, Essien Unyime Cosmas, Shindang John, Bigwan Emmanuel Isa. Serodiagnosis of Hepatitis B Virus Infection among Jessu Community of Gombe State, Nigeria. Int J Infect Dis Ther. 2018;3(2):40-44. doi: 10.11648/j.ijidt.20180302.14

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  • @article{10.11648/j.ijidt.20180302.14,
      author = {Sheyin Zakka and Frama Ishaku and Essien Unyime Cosmas and Shindang John and Bigwan Emmanuel Isa},
      title = {Serodiagnosis of Hepatitis B Virus Infection among Jessu Community of Gombe State, Nigeria},
      journal = {International Journal of Infectious Diseases and Therapy},
      volume = {3},
      number = {2},
      pages = {40-44},
      doi = {10.11648/j.ijidt.20180302.14},
      url = {https://doi.org/10.11648/j.ijidt.20180302.14},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ijidt.20180302.14},
      abstract = {Hepatitis B virus causes disease of the liver and is a global health problem that leads to liver cirrhosis and hepatocellular carcinoma. Despite the dangers posed by this silent and deadly disease, there is little or no documented work on Hepatitis B infections in Jessu community, Gombe State, North East Nigeria. This study was undertaken to determine the sero-prevalence of Hepatitis B Virus infection and possible risk factors associated with the transmission of HBV. Blood samples (3ml) were collected from 196 eligible consented subjects and the serum samples were tested for the presence of HBsAg using On Site HBsAg Rapid Test Kit manufactured by CTK Biotech, USA. The OnSite HBV 5-Parameter Rapid Test also manufactured by CTK Biotech, USA was used to confirm those that were positive. Of the 196 eligible subjects examined, 5.6% were confirmed positive for HBsAg, 8.6% were males and 2.9% were females. Age distribution of HBsAg among the population shows the highest seroprevalence of 8.9% HBsAg in ages 16-30 years, followed by 4.5% in ages 31-45 years while ages 0-15 years had 3.5% seroprevalence. Participants who share sharp objects recorded the highest prevalence of 6.3% HCV infection followed by blood transfusion with 5.9% prevalence and those with multiple sex partners had the least prevalence of 1.8% HCV infection. The seroprevalence of 5.6% HBV in this study indicated the presence of HBV in Jessu Community in Gombe State, North East Nigeria.},
     year = {2018}
    }
    

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  • TY  - JOUR
    T1  - Serodiagnosis of Hepatitis B Virus Infection among Jessu Community of Gombe State, Nigeria
    AU  - Sheyin Zakka
    AU  - Frama Ishaku
    AU  - Essien Unyime Cosmas
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    JO  - International Journal of Infectious Diseases and Therapy
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    PB  - Science Publishing Group
    SN  - 2578-966X
    UR  - https://doi.org/10.11648/j.ijidt.20180302.14
    AB  - Hepatitis B virus causes disease of the liver and is a global health problem that leads to liver cirrhosis and hepatocellular carcinoma. Despite the dangers posed by this silent and deadly disease, there is little or no documented work on Hepatitis B infections in Jessu community, Gombe State, North East Nigeria. This study was undertaken to determine the sero-prevalence of Hepatitis B Virus infection and possible risk factors associated with the transmission of HBV. Blood samples (3ml) were collected from 196 eligible consented subjects and the serum samples were tested for the presence of HBsAg using On Site HBsAg Rapid Test Kit manufactured by CTK Biotech, USA. The OnSite HBV 5-Parameter Rapid Test also manufactured by CTK Biotech, USA was used to confirm those that were positive. Of the 196 eligible subjects examined, 5.6% were confirmed positive for HBsAg, 8.6% were males and 2.9% were females. Age distribution of HBsAg among the population shows the highest seroprevalence of 8.9% HBsAg in ages 16-30 years, followed by 4.5% in ages 31-45 years while ages 0-15 years had 3.5% seroprevalence. Participants who share sharp objects recorded the highest prevalence of 6.3% HCV infection followed by blood transfusion with 5.9% prevalence and those with multiple sex partners had the least prevalence of 1.8% HCV infection. The seroprevalence of 5.6% HBV in this study indicated the presence of HBV in Jessu Community in Gombe State, North East Nigeria.
    VL  - 3
    IS  - 2
    ER  - 

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