Effect of Exercise on Some Haemostatic Parameters Among Students in a Tertiary Educational Institution in Nigeria

Benjamin Onyema Eledo; Reward Igwe; Okezie Caleb Okamgba; Sylvester Chibueze Izah

doi:doi:10.11648/j.ajhr.20170505.15

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Effect of Exercise on Some Haemostatic Parameters Among Students in a Tertiary Educational Institution in Nigeria

Benjamin Onyema Eledo, Reward Igwe, Okezie Caleb Okamgba, Sylvester Chibueze Izah

Published in American Journal of Health Research (Volume 5, Issue 5)

Received: 13 August 2017 Accepted: 28 August 2017 Published: 18 September 2017

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Abstract

This study investigated the effect of exercise on some haemostatic parameters among students from a tertiary institution in Nigeria. Fifty four individuals participated in this study, comprising 28 males and 26 females. Blood was collected from the participants before and after the rigorous exercise and the prothrombin time (PT), activated partial thromboplastin time (APTT) and platelets count (PLT) were analyzed using standard methodology. Results showed mean values before and after the exercise were 217.31 and 238.27 x10⁹/L for female, 228.75 and 240.18 x10⁹/L for male respectively (platelets counts), 14.25 and 12.08 seconds for female, 14.29 and 12.35 seconds for male respectively (prothrombin time) and 31.71 and 24.29 seconds for female and 30.62 and 23.43 seconds for male respectively (activated partial thromboplastin time). Statistically, there was significant variation (P<0.001) before and after exercise for PT, APTT, and no significant difference (P>0.05) for PLT count before and after exercise. PT and APTT showed significant decline after the exercise indicating activation of the coagulation cascade which may lead to hypercoagulability predisposing the subjects to an increased risk of cardiovascular derangement; while PLT showed no variation suggesting no risk of thrombocytopenia or thrombocytosis.

Published in	American Journal of Health Research (Volume 5, Issue 5)
DOI	10.11648/j.ajhr.20170505.15
Page(s)	145-148
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Exercise, Haemostatic Indices, Prothrombin Time, Activated Partial Thromboplastin Time, Blood Platelets

References

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[2]	Bhatti, R. and Shaikh, D. M. (2007). The effect of exercise on blood parameters. Pak J Physiol., 3(2): No page no.
[3]	Benoni, G., Bellavite, P., Adami, A., Chirumbolo, S., Lippi, G., Brocco, G., Cuzzolin, L. (1995). Effect of acute exercise on some haematological parameters and neutrophil functions in active and inactive subjects. European Journal of Applied Physiology and Occupational Physiology, 70(2): 187-191.
[4]	El-Sayed, M., Omar, A. and Lin, X. (2000). Post-exercise Alcohol ingestion perturbs blood haemostasis during recovery. Thrombosis Research, 99: 523-530.
[5]	Rostami, H., Aliyev, A., Madatova, V., Rostami, M. and Golchin, M. (2017). The Impact Of Short-time exercise on some of hemostatic factors in different tissues of rats. Advances in Biology & Earth Sciences, 2(1): 65-72.
[6]	Abdullah, W. Z. (2012). Shortened Activated Partial Thromboplastin Time (APTT): A Simple but Important Marker of Hypercoagulable State During Acute Coronary Event, Coronary Artery Disease – New Insights and Novel Approaches, Angelo Squeri (Ed.), ISBN: 978-953-51-0344-8, In Tech.
[7]	Moore, S. (2011). Exercise & Low Platelet Count. http://www.livestrong.com/article/127280-foods-increase-blood-platelets/. Accessed August 12, 2017.
[8]	El-Sayed, M. S. (1996). Effects of Exercise on Blood Coagulation, Fibrinolysis and Platelet Aggregation. Sports Medicine, 22(5): 282-298.
[9]	Khalid, A. and Zafar, L. (2015). Effect of Haemodialysis on Mean Prothrombin Time and Activated Partial Thromboplastin Time in Patients of End Stage Renal Disease. Journal of Rawalpindi Medical College, 19(3): 247-249.
[10]	Peterson, P. and Gottfried, E. L. (1982). The effects of inaccurate blood sample volume on prothrombin time (PT) and activated partial thromboplastin time (aPTT). Thromb. Haemost., 47(2): 101-103.
[11]	Lippia, G., Salvagnob, G. L., Ippolitoa, L., Franchinic, M. and Favalorod, E. J. (2010). Shortened activated partial thromboplastin time: causes and management. Blood Coagulation and Fibrinolysis, 21: 459-463.
[12]	BoneMarrow (2017). Exercising with a Low Platelet Count. http://www.bonemarrowmx.com/exercising-with-a-low-platelet-count/. Accessed August 12, 2017.
[13]	Wang J. S., Jen C. J., Kung H. C., Lin L. J., Hsiue T. R. and Chen H. I. (1994) Different effect of strenuous exercise and moderate exercise on platelet function in men. Circulation, 90(6): 2877-2885.
[14]	Wang, J-S., Jen, C. J. and Chen, H. (1995). Effects of Exercise Training and Deconditioning on Platelet Function in Men. Arteriosclerosis, Thrombosis, and Vascular Biology, 15: 1668-1674.
[15]	Tripodi, A., Chantarangkul, V., Martinelli, I., Bucciarelli, P. and Mannucci, P. M. (2004). A shortened activated partial thromboplastin time is associated with the risk of venous thromboembolism. Blood, 104: 3631-3634.

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APA Style

Benjamin Onyema Eledo, Reward Igwe, Okezie Caleb Okamgba, Sylvester Chibueze Izah. (2017). Effect of Exercise on Some Haemostatic Parameters Among Students in a Tertiary Educational Institution in Nigeria. American Journal of Health Research, 5(5), 145-148. https://doi.org/10.11648/j.ajhr.20170505.15

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ACS Style

Benjamin Onyema Eledo; Reward Igwe; Okezie Caleb Okamgba; Sylvester Chibueze Izah. Effect of Exercise on Some Haemostatic Parameters Among Students in a Tertiary Educational Institution in Nigeria. Am. J. Health Res. 2017, 5(5), 145-148. doi: 10.11648/j.ajhr.20170505.15

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AMA Style

Benjamin Onyema Eledo, Reward Igwe, Okezie Caleb Okamgba, Sylvester Chibueze Izah. Effect of Exercise on Some Haemostatic Parameters Among Students in a Tertiary Educational Institution in Nigeria. Am J Health Res. 2017;5(5):145-148. doi: 10.11648/j.ajhr.20170505.15

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@article{10.11648/j.ajhr.20170505.15,
  author = {Benjamin Onyema Eledo and Reward Igwe and Okezie Caleb Okamgba and Sylvester Chibueze Izah},
  title = {Effect of Exercise on Some Haemostatic Parameters Among Students in a Tertiary Educational Institution in Nigeria},
  journal = {American Journal of Health Research},
  volume = {5},
  number = {5},
  pages = {145-148},
  doi = {10.11648/j.ajhr.20170505.15},
  url = {https://doi.org/10.11648/j.ajhr.20170505.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajhr.20170505.15},
  abstract = {This study investigated the effect of exercise on some haemostatic parameters among students from a tertiary institution in Nigeria. Fifty four individuals participated in this study, comprising 28 males and 26 females. Blood was collected from the participants before and after the rigorous exercise and the prothrombin time (PT), activated partial thromboplastin time (APTT) and platelets count (PLT) were analyzed using standard methodology. Results showed mean values before and after the exercise were 217.31 and 238.27 x109/L for female, 228.75 and 240.18 x109/L for male respectively (platelets counts), 14.25 and 12.08 seconds for female, 14.29 and 12.35 seconds for male respectively (prothrombin time) and 31.71 and 24.29 seconds for female and 30.62 and 23.43 seconds for male respectively (activated partial thromboplastin time). Statistically, there was significant variation (P<0.001) before and after exercise for PT, APTT, and no significant difference (P>0.05) for PLT count before and after exercise. PT and APTT showed significant decline after the exercise indicating activation of the coagulation cascade which may lead to hypercoagulability predisposing the subjects to an increased risk of cardiovascular derangement; while PLT showed no variation suggesting no risk of thrombocytopenia or thrombocytosis.},
 year = {2017}
}

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TY  - JOUR
T1  - Effect of Exercise on Some Haemostatic Parameters Among Students in a Tertiary Educational Institution in Nigeria
AU  - Benjamin Onyema Eledo
AU  - Reward Igwe
AU  - Okezie Caleb Okamgba
AU  - Sylvester Chibueze Izah
Y1  - 2017/09/18
PY  - 2017
N1  - https://doi.org/10.11648/j.ajhr.20170505.15
DO  - 10.11648/j.ajhr.20170505.15
T2  - American Journal of Health Research
JF  - American Journal of Health Research
JO  - American Journal of Health Research
SP  - 145
EP  - 148
PB  - Science Publishing Group
SN  - 2330-8796
UR  - https://doi.org/10.11648/j.ajhr.20170505.15
AB  - This study investigated the effect of exercise on some haemostatic parameters among students from a tertiary institution in Nigeria. Fifty four individuals participated in this study, comprising 28 males and 26 females. Blood was collected from the participants before and after the rigorous exercise and the prothrombin time (PT), activated partial thromboplastin time (APTT) and platelets count (PLT) were analyzed using standard methodology. Results showed mean values before and after the exercise were 217.31 and 238.27 x109/L for female, 228.75 and 240.18 x109/L for male respectively (platelets counts), 14.25 and 12.08 seconds for female, 14.29 and 12.35 seconds for male respectively (prothrombin time) and 31.71 and 24.29 seconds for female and 30.62 and 23.43 seconds for male respectively (activated partial thromboplastin time). Statistically, there was significant variation (P<0.001) before and after exercise for PT, APTT, and no significant difference (P>0.05) for PLT count before and after exercise. PT and APTT showed significant decline after the exercise indicating activation of the coagulation cascade which may lead to hypercoagulability predisposing the subjects to an increased risk of cardiovascular derangement; while PLT showed no variation suggesting no risk of thrombocytopenia or thrombocytosis.
VL  - 5
IS  - 5
ER  -

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Author Information

Benjamin Onyema Eledo

Department of Medical Laboratory Science, Faculty of Health Sciences, Madonna University, Elele, Nigeria; Haematology and Blood Transfusion Department Federal Medical Centre, Yenagoa, Nigeria
Reward Igwe

Department of Medical Laboratory Science, Faculty of Health Sciences, Madonna University, Elele, Nigeria
Okezie Caleb Okamgba

Department of Medical Laboratory Science, Abia State University, Uturu, Nigeria
Sylvester Chibueze Izah

Department of Biological Sciences, Faculty of Science, Niger Delta University, Wilberforce Island, Nigeria

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APA Style

Benjamin Onyema Eledo, Reward Igwe, Okezie Caleb Okamgba, Sylvester Chibueze Izah. (2017). Effect of Exercise on Some Haemostatic Parameters Among Students in a Tertiary Educational Institution in Nigeria. American Journal of Health Research, 5(5), 145-148. https://doi.org/10.11648/j.ajhr.20170505.15

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ACS Style

Benjamin Onyema Eledo; Reward Igwe; Okezie Caleb Okamgba; Sylvester Chibueze Izah. Effect of Exercise on Some Haemostatic Parameters Among Students in a Tertiary Educational Institution in Nigeria. Am. J. Health Res. 2017, 5(5), 145-148. doi: 10.11648/j.ajhr.20170505.15

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AMA Style

Benjamin Onyema Eledo, Reward Igwe, Okezie Caleb Okamgba, Sylvester Chibueze Izah. Effect of Exercise on Some Haemostatic Parameters Among Students in a Tertiary Educational Institution in Nigeria. Am J Health Res. 2017;5(5):145-148. doi: 10.11648/j.ajhr.20170505.15

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@article{10.11648/j.ajhr.20170505.15,
  author = {Benjamin Onyema Eledo and Reward Igwe and Okezie Caleb Okamgba and Sylvester Chibueze Izah},
  title = {Effect of Exercise on Some Haemostatic Parameters Among Students in a Tertiary Educational Institution in Nigeria},
  journal = {American Journal of Health Research},
  volume = {5},
  number = {5},
  pages = {145-148},
  doi = {10.11648/j.ajhr.20170505.15},
  url = {https://doi.org/10.11648/j.ajhr.20170505.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajhr.20170505.15},
  abstract = {This study investigated the effect of exercise on some haemostatic parameters among students from a tertiary institution in Nigeria. Fifty four individuals participated in this study, comprising 28 males and 26 females. Blood was collected from the participants before and after the rigorous exercise and the prothrombin time (PT), activated partial thromboplastin time (APTT) and platelets count (PLT) were analyzed using standard methodology. Results showed mean values before and after the exercise were 217.31 and 238.27 x109/L for female, 228.75 and 240.18 x109/L for male respectively (platelets counts), 14.25 and 12.08 seconds for female, 14.29 and 12.35 seconds for male respectively (prothrombin time) and 31.71 and 24.29 seconds for female and 30.62 and 23.43 seconds for male respectively (activated partial thromboplastin time). Statistically, there was significant variation (P<0.001) before and after exercise for PT, APTT, and no significant difference (P>0.05) for PLT count before and after exercise. PT and APTT showed significant decline after the exercise indicating activation of the coagulation cascade which may lead to hypercoagulability predisposing the subjects to an increased risk of cardiovascular derangement; while PLT showed no variation suggesting no risk of thrombocytopenia or thrombocytosis.},
 year = {2017}
}

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TY  - JOUR
T1  - Effect of Exercise on Some Haemostatic Parameters Among Students in a Tertiary Educational Institution in Nigeria
AU  - Benjamin Onyema Eledo
AU  - Reward Igwe
AU  - Okezie Caleb Okamgba
AU  - Sylvester Chibueze Izah
Y1  - 2017/09/18
PY  - 2017
N1  - https://doi.org/10.11648/j.ajhr.20170505.15
DO  - 10.11648/j.ajhr.20170505.15
T2  - American Journal of Health Research
JF  - American Journal of Health Research
JO  - American Journal of Health Research
SP  - 145
EP  - 148
PB  - Science Publishing Group
SN  - 2330-8796
UR  - https://doi.org/10.11648/j.ajhr.20170505.15
AB  - This study investigated the effect of exercise on some haemostatic parameters among students from a tertiary institution in Nigeria. Fifty four individuals participated in this study, comprising 28 males and 26 females. Blood was collected from the participants before and after the rigorous exercise and the prothrombin time (PT), activated partial thromboplastin time (APTT) and platelets count (PLT) were analyzed using standard methodology. Results showed mean values before and after the exercise were 217.31 and 238.27 x109/L for female, 228.75 and 240.18 x109/L for male respectively (platelets counts), 14.25 and 12.08 seconds for female, 14.29 and 12.35 seconds for male respectively (prothrombin time) and 31.71 and 24.29 seconds for female and 30.62 and 23.43 seconds for male respectively (activated partial thromboplastin time). Statistically, there was significant variation (P<0.001) before and after exercise for PT, APTT, and no significant difference (P>0.05) for PLT count before and after exercise. PT and APTT showed significant decline after the exercise indicating activation of the coagulation cascade which may lead to hypercoagulability predisposing the subjects to an increased risk of cardiovascular derangement; while PLT showed no variation suggesting no risk of thrombocytopenia or thrombocytosis.
VL  - 5
IS  - 5
ER  -

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