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Homocysteinemia Level Determination Among Retired People in Bobo Dioulasso, Burkina Faso

Received: 30 May 2023    Accepted: 25 June 2023    Published: 11 July 2023
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Abstract

Hyperhomocysteinemia, currently a public health problem, has been associated with the onset of critical diseases among elderly persons. Our aim in this study was to determine homocysteinemia levels in retired people. A cross sectional study was carried out among retired people in Bobo Dioulasso. Sociodemographic and clinico-biological variables were collected. Quantitative determination of total homocysteinemia in serum was carried out by a chemiluminescence microparticle immunoassay (CMIA). Three homocysteinemia levels were considered: moderate (16-30 µmol/L), intermediate (31-100 µmol/L), and severe (>100 µmol/L). Fisher's exact test was used to examine the significance of the association with a p-value of 0.05. We included a total of 71 retired people, with a median age of 64 years [minimum - maximum: 45 - 92 years], Hyperhomocysteinemia between [16-30 µmol/L [was observed in 16.90% (12/71) with a median homocysteinemia value equal to 18.71 µmol/L [minimum - maximum = 16.57 - 26.60 µmol/L]. Hyperhomocysteinemia was not significantly associated with increased blood pressure (p = 0.817), age group (p = 0.958), sex (p = 0.106), body mass index (0.053), estimated GFR (p = 0.590). A low frequency of moderate hyperhomocysteinemia was recorded in retired persons in Bobo-Dioulasso. An investigation of genetic polymorphisms associated with hyperhomocysteinemia could be considered.

Published in Advances in Biochemistry (Volume 11, Issue 3)
DOI 10.11648/j.ab.20231103.11
Page(s) 29-33
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This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Homocysteinemia, Retired Persons, Burkina Faso

References
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    Ollo Da, Souleymane Fofana, Emmanuel Zongo, Arnaud Kouraogo, Dieudonne Sanon, et al. (2023). Homocysteinemia Level Determination Among Retired People in Bobo Dioulasso, Burkina Faso. Advances in Biochemistry, 11(3), 29-33. https://doi.org/10.11648/j.ab.20231103.11

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    ACS Style

    Ollo Da; Souleymane Fofana; Emmanuel Zongo; Arnaud Kouraogo; Dieudonne Sanon, et al. Homocysteinemia Level Determination Among Retired People in Bobo Dioulasso, Burkina Faso. Adv. Biochem. 2023, 11(3), 29-33. doi: 10.11648/j.ab.20231103.11

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    AMA Style

    Ollo Da, Souleymane Fofana, Emmanuel Zongo, Arnaud Kouraogo, Dieudonne Sanon, et al. Homocysteinemia Level Determination Among Retired People in Bobo Dioulasso, Burkina Faso. Adv Biochem. 2023;11(3):29-33. doi: 10.11648/j.ab.20231103.11

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  • @article{10.11648/j.ab.20231103.11,
      author = {Ollo Da and Souleymane Fofana and Emmanuel Zongo and Arnaud Kouraogo and Dieudonne Sanon and Adama Hermann Traore and Fatou Gueye Tall and Sanata Bamba and Georges Anicet Ouedraogo},
      title = {Homocysteinemia Level Determination Among Retired People in Bobo Dioulasso, Burkina Faso},
      journal = {Advances in Biochemistry},
      volume = {11},
      number = {3},
      pages = {29-33},
      doi = {10.11648/j.ab.20231103.11},
      url = {https://doi.org/10.11648/j.ab.20231103.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ab.20231103.11},
      abstract = {Hyperhomocysteinemia, currently a public health problem, has been associated with the onset of critical diseases among elderly persons. Our aim in this study was to determine homocysteinemia levels in retired people. A cross sectional study was carried out among retired people in Bobo Dioulasso. Sociodemographic and clinico-biological variables were collected. Quantitative determination of total homocysteinemia in serum was carried out by a chemiluminescence microparticle immunoassay (CMIA). Three homocysteinemia levels were considered: moderate (16-30 µmol/L), intermediate (31-100 µmol/L), and severe (>100 µmol/L). Fisher's exact test was used to examine the significance of the association with a p-value of 0.05. We included a total of 71 retired people, with a median age of 64 years [minimum - maximum: 45 - 92 years], Hyperhomocysteinemia between [16-30 µmol/L [was observed in 16.90% (12/71) with a median homocysteinemia value equal to 18.71 µmol/L [minimum - maximum = 16.57 - 26.60 µmol/L]. Hyperhomocysteinemia was not significantly associated with increased blood pressure (p = 0.817), age group (p = 0.958), sex (p = 0.106), body mass index (0.053), estimated GFR (p = 0.590). A low frequency of moderate hyperhomocysteinemia was recorded in retired persons in Bobo-Dioulasso. An investigation of genetic polymorphisms associated with hyperhomocysteinemia could be considered.},
     year = {2023}
    }
    

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  • TY  - JOUR
    T1  - Homocysteinemia Level Determination Among Retired People in Bobo Dioulasso, Burkina Faso
    AU  - Ollo Da
    AU  - Souleymane Fofana
    AU  - Emmanuel Zongo
    AU  - Arnaud Kouraogo
    AU  - Dieudonne Sanon
    AU  - Adama Hermann Traore
    AU  - Fatou Gueye Tall
    AU  - Sanata Bamba
    AU  - Georges Anicet Ouedraogo
    Y1  - 2023/07/11
    PY  - 2023
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    DO  - 10.11648/j.ab.20231103.11
    T2  - Advances in Biochemistry
    JF  - Advances in Biochemistry
    JO  - Advances in Biochemistry
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    EP  - 33
    PB  - Science Publishing Group
    SN  - 2329-0862
    UR  - https://doi.org/10.11648/j.ab.20231103.11
    AB  - Hyperhomocysteinemia, currently a public health problem, has been associated with the onset of critical diseases among elderly persons. Our aim in this study was to determine homocysteinemia levels in retired people. A cross sectional study was carried out among retired people in Bobo Dioulasso. Sociodemographic and clinico-biological variables were collected. Quantitative determination of total homocysteinemia in serum was carried out by a chemiluminescence microparticle immunoassay (CMIA). Three homocysteinemia levels were considered: moderate (16-30 µmol/L), intermediate (31-100 µmol/L), and severe (>100 µmol/L). Fisher's exact test was used to examine the significance of the association with a p-value of 0.05. We included a total of 71 retired people, with a median age of 64 years [minimum - maximum: 45 - 92 years], Hyperhomocysteinemia between [16-30 µmol/L [was observed in 16.90% (12/71) with a median homocysteinemia value equal to 18.71 µmol/L [minimum - maximum = 16.57 - 26.60 µmol/L]. Hyperhomocysteinemia was not significantly associated with increased blood pressure (p = 0.817), age group (p = 0.958), sex (p = 0.106), body mass index (0.053), estimated GFR (p = 0.590). A low frequency of moderate hyperhomocysteinemia was recorded in retired persons in Bobo-Dioulasso. An investigation of genetic polymorphisms associated with hyperhomocysteinemia could be considered.
    VL  - 11
    IS  - 3
    ER  - 

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Author Information
  • Department of Medical Biochemistry, Center Hospital University Souro SANOU, Bobo-Dioulasso, Burkina Faso

  • Department of Medical Biochemistry, Center Hospital University Souro SANOU, Bobo-Dioulasso, Burkina Faso

  • Department of Medical Biochemistry, Center Hospital University Souro SANOU, Bobo-Dioulasso, Burkina Faso

  • Department of Medical Biochemistry, Center Hospital University Souro SANOU, Bobo-Dioulasso, Burkina Faso

  • Department of Medical Biochemistry, Center Hospital University Souro SANOU, Bobo-Dioulasso, Burkina Faso

  • Department of Medical Biochemistry, Center Hospital University Souro SANOU, Bobo-Dioulasso, Burkina Faso

  • Department of Pharmaceutical Biochemistry, Faculty of Medicine, Pharmacy and Odontostomatology, Cheikh Anta Diop University, Dakar, Senegal

  • Department of Medical Biochemistry, Center Hospital University Souro SANOU, Bobo-Dioulasso, Burkina Faso

  • Laboratory of Research in Health Science and Animal Biotechnology (LARESBA), Nazi BONI University (UNB), Bobo-Dioulasso, Burkina Faso

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