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The Features of the Course of Traumatic Brain Disease in Persons with Combat Traumatic Brain Injury

Received: 29 August 2022    Accepted: 20 September 2022    Published: 9 January 2023
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Abstract

This article is devoted to the problem of survival and prognosis of treatment outcomes of patients with traumatic brain injury who have sustained craniocerebral trauma according to changes in neurospecific protein (S100β) levels during the acute period of trauma. The material includes data from the examination of 250 combatants and invalids who sustained craniocerebral trauma in the ATO-JFO zone at the neurological department of the Regional Hospital for War Veterans. An analysis of the course and results of treatment of patients who had sustained severe craniocerebral trauma was carried out. Patients underwent routine biochemical examinations, neuroimaging studies and neurospecific protein (S100β) levels examination in the acute period of trauma. On the basis of the data obtained, it was found that the level of neurospecific protein S100β in the blood serum takes a great role in predicting the course and outcome of the disease.

Published in American Journal of Clinical and Experimental Medicine (Volume 11, Issue 1)
DOI 10.11648/j.ajcem.20231101.12
Page(s) 5-8
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Brain Injury, Acubarotrauma, Neurospecific Protein S100β

References
[1] Voloshin P. V. Neurological aspects of periodization of traumatic brain injury / P. V. Voloshin, I. I. Shogam // Vopr. neurosurgeon. - 1990. - No. 6. - S. 25-27.
[2] Dvoryanchikov N. A. Military medical examination of military personnel with wounds and injuries of the central nervous system with explosive trauma / N. A. Dvoryanchikov, S. V. Klepikov, N. I. Polyanko // Combat trauma of the nervous system in modern wars. - M., 2002. - S. 140-143.
[3] Saliy Z. V. Features of the long-term consequences of traumatic brain injury. Bulletin of Scientific Research. 2016; 1: 92-5. 314.
[4] Saliy Z. V., Shkrobot S. I., Saliy I. I. Morphological features of the consequences of operated intracerebral hematomas. Ukrainian Journal of Neurology. 2014; 3-4: 117.
[5] Chernenko I. I., Chukhno I. A. Epidemiological and clinical aspects of the consequences of traumatic brain injury / I. I. Chernenko, I. A. Chukhno // Bulletin of Social Hygiene and Health Care Organization of Ukraine. - 2017. - № 4. (74) - P. 5-11.
[6] Chernenko I. I., Chukhno I. A. Medico-social consequences of the transferred craniocerebral trauma / І. І. Chernenko, I. A. Chukhno // International Journal of Innovative Technologies in Social Science. - 2018. - 1 (5) February. - P. 26-29.
[7] Yavorska V. O., Chernenko I. I., Fedchenko Yu. G., Bondar O. B., Bondar B. E. Changes in blood supply in patients with combat traumatic brain injury of varying severity // Ukrainian Bulletin of Psychoneurology. Vol. 21, issue 1 (74), 2013. - P. 28-33.
[8] Konstantinou N., Pettemeridou E., Seimenis I. Assessing the Relationship between Neurocognitive Performance and Brain Volume in 334 Chronic Moderate–Severe Traumatic Brain Injury. Frontiers in Neurology. 2016: 7: 126-32.
[9] Polinder S., Haagsma J. A., van Klaveren D. et al. Health-related quality of life after TBI: a systematic review of study design, instruments, measurement properties, and outcome. Polinder, Popul Health Metr. 2015; 13 (1): 1-12.
[10] Scholten A. C., Haagsma J. A., Andriessen T. M. Health-related quality of life after mild, moderate and severe traumatic brain injury: patterns and predictors of suboptimal functioning during the first year after injury. Injury. 2015; 46 (4): 616-24.
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  • APA Style

    Chernenko Inna. (2023). The Features of the Course of Traumatic Brain Disease in Persons with Combat Traumatic Brain Injury. American Journal of Clinical and Experimental Medicine, 11(1), 5-8. https://doi.org/10.11648/j.ajcem.20231101.12

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    ACS Style

    Chernenko Inna. The Features of the Course of Traumatic Brain Disease in Persons with Combat Traumatic Brain Injury. Am. J. Clin. Exp. Med. 2023, 11(1), 5-8. doi: 10.11648/j.ajcem.20231101.12

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    AMA Style

    Chernenko Inna. The Features of the Course of Traumatic Brain Disease in Persons with Combat Traumatic Brain Injury. Am J Clin Exp Med. 2023;11(1):5-8. doi: 10.11648/j.ajcem.20231101.12

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  • @article{10.11648/j.ajcem.20231101.12,
      author = {Chernenko Inna},
      title = {The Features of the Course of Traumatic Brain Disease in Persons with Combat Traumatic Brain Injury},
      journal = {American Journal of Clinical and Experimental Medicine},
      volume = {11},
      number = {1},
      pages = {5-8},
      doi = {10.11648/j.ajcem.20231101.12},
      url = {https://doi.org/10.11648/j.ajcem.20231101.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajcem.20231101.12},
      abstract = {This article is devoted to the problem of survival and prognosis of treatment outcomes of patients with traumatic brain injury who have sustained craniocerebral trauma according to changes in neurospecific protein (S100β) levels during the acute period of trauma. The material includes data from the examination of 250 combatants and invalids who sustained craniocerebral trauma in the ATO-JFO zone at the neurological department of the Regional Hospital for War Veterans. An analysis of the course and results of treatment of patients who had sustained severe craniocerebral trauma was carried out. Patients underwent routine biochemical examinations, neuroimaging studies and neurospecific protein (S100β) levels examination in the acute period of trauma. On the basis of the data obtained, it was found that the level of neurospecific protein S100β in the blood serum takes a great role in predicting the course and outcome of the disease.},
     year = {2023}
    }
    

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Author Information
  • Department of Neurology, Psychiatry, Narcology and Medical Psychology, Kharkiv National University by V. Karasin, Kharkov, Ukraine

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