Introduction: Screening program of congenital hypothyroidism is one of crucial evaluation in newborn period, because early detection and prompt treatment can prevent mental retardation. This screening is quite simple, and the result was revealed quickly. Beside devastating effect to central nervous system, undiagnosed congenital hypothyroidism also affect skeleton and bone maturation. Hypothyroidism constitutes about 25-30% cases of short stature in the developing nations. Case: A 6 years-old female referred to the Sanglah General Hospital in December 2021 with short stature and delayed milestone of development. She cannot walk and talk like normal children in her age. Patient performed thyroid profile and it suggest hypothyroidism with low FT4 0,42 ng/dL and high level of TSH 119,79 IU/ml. Bone age revealed delayed in bone maturation according to girls 8 months age. Patient got levothyroxine with dosage 12 mcg/kg/day (100 mcg/day) in December 2021. After one months of treatment, thyroid profile showed improvement TSHs still above normal 16,36, FT4 was normal 0,78. Conclusion: There is still cases of delay diagnosis and treatment of CH in developing country due to lack of screening program in newborn, low parental education level which led to devastating outcome for neuro muscular development.
| Published in | American Journal of Pediatrics (Volume 8, Issue 3) |
| DOI | 10.11648/j.ajp.20220803.16 |
| Page(s) | 181-184 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Late Diagnosis, Congenital Hypothyroid, Outcome
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APA Style
Luh Putu Eka Sari Kresnandari, I Made Arimbawa, I Made Darma Yuda. (2022). Delayed Diagnosis of Congenital Hypothyroid: Concealed Problem in Developing Countries. American Journal of Pediatrics, 8(3), 181-184. https://doi.org/10.11648/j.ajp.20220803.16
ACS Style
Luh Putu Eka Sari Kresnandari; I Made Arimbawa; I Made Darma Yuda. Delayed Diagnosis of Congenital Hypothyroid: Concealed Problem in Developing Countries. Am. J. Pediatr. 2022, 8(3), 181-184. doi: 10.11648/j.ajp.20220803.16
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Download@article{10.11648/j.ajp.20220803.16,
author = {Luh Putu Eka Sari Kresnandari and I Made Arimbawa and I Made Darma Yuda},
title = {Delayed Diagnosis of Congenital Hypothyroid: Concealed Problem in Developing Countries},
journal = {American Journal of Pediatrics},
volume = {8},
number = {3},
pages = {181-184},
doi = {10.11648/j.ajp.20220803.16},
url = {https://doi.org/10.11648/j.ajp.20220803.16},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajp.20220803.16},
abstract = {Introduction: Screening program of congenital hypothyroidism is one of crucial evaluation in newborn period, because early detection and prompt treatment can prevent mental retardation. This screening is quite simple, and the result was revealed quickly. Beside devastating effect to central nervous system, undiagnosed congenital hypothyroidism also affect skeleton and bone maturation. Hypothyroidism constitutes about 25-30% cases of short stature in the developing nations. Case: A 6 years-old female referred to the Sanglah General Hospital in December 2021 with short stature and delayed milestone of development. She cannot walk and talk like normal children in her age. Patient performed thyroid profile and it suggest hypothyroidism with low FT4 0,42 ng/dL and high level of TSH 119,79 IU/ml. Bone age revealed delayed in bone maturation according to girls 8 months age. Patient got levothyroxine with dosage 12 mcg/kg/day (100 mcg/day) in December 2021. After one months of treatment, thyroid profile showed improvement TSHs still above normal 16,36, FT4 was normal 0,78. Conclusion: There is still cases of delay diagnosis and treatment of CH in developing country due to lack of screening program in newborn, low parental education level which led to devastating outcome for neuro muscular development.},
year = {2022}
}
TY - JOUR T1 - Delayed Diagnosis of Congenital Hypothyroid: Concealed Problem in Developing Countries AU - Luh Putu Eka Sari Kresnandari AU - I Made Arimbawa AU - I Made Darma Yuda Y1 - 2022/08/24 PY - 2022 N1 - https://doi.org/10.11648/j.ajp.20220803.16 DO - 10.11648/j.ajp.20220803.16 T2 - American Journal of Pediatrics JF - American Journal of Pediatrics JO - American Journal of Pediatrics SP - 181 EP - 184 PB - Science Publishing Group SN - 2472-0909 UR - https://doi.org/10.11648/j.ajp.20220803.16 AB - Introduction: Screening program of congenital hypothyroidism is one of crucial evaluation in newborn period, because early detection and prompt treatment can prevent mental retardation. This screening is quite simple, and the result was revealed quickly. Beside devastating effect to central nervous system, undiagnosed congenital hypothyroidism also affect skeleton and bone maturation. Hypothyroidism constitutes about 25-30% cases of short stature in the developing nations. Case: A 6 years-old female referred to the Sanglah General Hospital in December 2021 with short stature and delayed milestone of development. She cannot walk and talk like normal children in her age. Patient performed thyroid profile and it suggest hypothyroidism with low FT4 0,42 ng/dL and high level of TSH 119,79 IU/ml. Bone age revealed delayed in bone maturation according to girls 8 months age. Patient got levothyroxine with dosage 12 mcg/kg/day (100 mcg/day) in December 2021. After one months of treatment, thyroid profile showed improvement TSHs still above normal 16,36, FT4 was normal 0,78. Conclusion: There is still cases of delay diagnosis and treatment of CH in developing country due to lack of screening program in newborn, low parental education level which led to devastating outcome for neuro muscular development. VL - 8 IS - 3 ER -
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