Cognitive Functions in Patients with Idiopathic Normal Pressure Hydrocephalus Before and After Ventriculoperitoneal Shunt

Mohamed Hamdy Ismail; Ahmed Ragab; Hossam Mohamed Refat; Hassan Abaza

doi:doi:10.11648/j.cnn.20230703.12

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Cognitive Functions in Patients with Idiopathic Normal Pressure Hydrocephalus Before and After Ventriculoperitoneal Shunt

Mohamed Hamdy Ismail, Ahmed Ragab, Hossam Mohamed Refat, Hassan Abaza

Published in Clinical Neurology and Neuroscience (Volume 7, Issue 3)

Received: 20 August 2023 Accepted: 8 September 2023 Published: 25 September 2023

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Abstract

Background: Clinical manifestations of idiopathic normal pressure hydrocephalus [iNPH] involve dementia, urinary incontinence and gait disturbance. Idiopathic normal pressure hydrocephalus treatment for short- and long-term improvement and maintenance of gait and also cognitive function is essential for reducing the caregiving burden on families and society. Methods: this study was done on 41participants with a diagnosis of iNPH, subjected to detailed medical and neurological history taking and neuropsychological assessment for cognitive functions before and after ventriculoperitoneal shunt operation. Results: After CSF (cerebro-spinal fluid) shunting, around 80.5% of cases with idiopathic normal pressure hydrocephalus demonstrated enhanced and sustained cognitive function for at least 1 year post-operatively and our study revealed that younger age and less severe idiopathic normal pressure hydrocephalus led to a good long-term prognosis of cognitive function. Conclusions: Individuals with idiopathic normal pressure hydrocephalus experienced improved cognitive function 3-12 months after CSF shunt operation, with greater improvement seen in younger patients with milder illness. Therefore, early identification and appropriate treatment are crucial for long-term recovery and preservation of cognitive function in idiopathic normal pressure hydrocephalus. Early diagnosis of iNPH followed by CSF Shunt treatment can improve cognitive functions. Long-term evaluations of cognitive functions after V-P (ventriculo peritoneal) shunt operation are recommended.

Published in	Clinical Neurology and Neuroscience (Volume 7, Issue 3)
DOI	10.11648/j.cnn.20230703.12
Page(s)	51-55
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

INPH, CSF, INPHGS, MRI, V-P shunt, MMSE, MOCA, AD

References

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APA Style

Mohamed Hamdy Ismail, Ahmed Ragab, Hossam Mohamed Refat, Hassan Abaza. (2023). Cognitive Functions in Patients with Idiopathic Normal Pressure Hydrocephalus Before and After Ventriculoperitoneal Shunt. Clinical Neurology and Neuroscience, 7(3), 51-55. https://doi.org/10.11648/j.cnn.20230703.12

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ACS Style

Mohamed Hamdy Ismail; Ahmed Ragab; Hossam Mohamed Refat; Hassan Abaza. Cognitive Functions in Patients with Idiopathic Normal Pressure Hydrocephalus Before and After Ventriculoperitoneal Shunt. Clin. Neurol. Neurosci. 2023, 7(3), 51-55. doi: 10.11648/j.cnn.20230703.12

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AMA Style

Mohamed Hamdy Ismail, Ahmed Ragab, Hossam Mohamed Refat, Hassan Abaza. Cognitive Functions in Patients with Idiopathic Normal Pressure Hydrocephalus Before and After Ventriculoperitoneal Shunt. Clin Neurol Neurosci. 2023;7(3):51-55. doi: 10.11648/j.cnn.20230703.12

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@article{10.11648/j.cnn.20230703.12,
  author = {Mohamed Hamdy Ismail and Ahmed Ragab and Hossam Mohamed Refat and Hassan Abaza},
  title = {Cognitive Functions in Patients with Idiopathic Normal Pressure Hydrocephalus Before and After Ventriculoperitoneal Shunt},
  journal = {Clinical Neurology and Neuroscience},
  volume = {7},
  number = {3},
  pages = {51-55},
  doi = {10.11648/j.cnn.20230703.12},
  url = {https://doi.org/10.11648/j.cnn.20230703.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cnn.20230703.12},
  abstract = {Background: Clinical manifestations of idiopathic normal pressure hydrocephalus [iNPH] involve dementia, urinary incontinence and gait disturbance. Idiopathic normal pressure hydrocephalus treatment for short- and long-term improvement and maintenance of gait and also cognitive function is essential for reducing the caregiving burden on families and society. Methods: this study was done on 41participants with a diagnosis of iNPH, subjected to detailed medical and neurological history taking and neuropsychological assessment for cognitive functions before and after ventriculoperitoneal shunt operation. Results: After CSF (cerebro-spinal fluid) shunting, around 80.5% of cases with idiopathic normal pressure hydrocephalus demonstrated enhanced and sustained cognitive function for at least 1 year post-operatively and our study revealed that younger age and less severe idiopathic normal pressure hydrocephalus led to a good long-term prognosis of cognitive function. Conclusions: Individuals with idiopathic normal pressure hydrocephalus experienced improved cognitive function 3-12 months after CSF shunt operation, with greater improvement seen in younger patients with milder illness. Therefore, early identification and appropriate treatment are crucial for long-term recovery and preservation of cognitive function in idiopathic normal pressure hydrocephalus. Early diagnosis of iNPH followed by CSF Shunt treatment can improve cognitive functions. Long-term evaluations of cognitive functions after V-P (ventriculo peritoneal) shunt operation are recommended.},
 year = {2023}
}

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TY  - JOUR
T1  - Cognitive Functions in Patients with Idiopathic Normal Pressure Hydrocephalus Before and After Ventriculoperitoneal Shunt
AU  - Mohamed Hamdy Ismail
AU  - Ahmed Ragab
AU  - Hossam Mohamed Refat
AU  - Hassan Abaza
Y1  - 2023/09/25
PY  - 2023
N1  - https://doi.org/10.11648/j.cnn.20230703.12
DO  - 10.11648/j.cnn.20230703.12
T2  - Clinical Neurology and Neuroscience
JF  - Clinical Neurology and Neuroscience
JO  - Clinical Neurology and Neuroscience
SP  - 51
EP  - 55
PB  - Science Publishing Group
SN  - 2578-8930
UR  - https://doi.org/10.11648/j.cnn.20230703.12
AB  - Background: Clinical manifestations of idiopathic normal pressure hydrocephalus [iNPH] involve dementia, urinary incontinence and gait disturbance. Idiopathic normal pressure hydrocephalus treatment for short- and long-term improvement and maintenance of gait and also cognitive function is essential for reducing the caregiving burden on families and society. Methods: this study was done on 41participants with a diagnosis of iNPH, subjected to detailed medical and neurological history taking and neuropsychological assessment for cognitive functions before and after ventriculoperitoneal shunt operation. Results: After CSF (cerebro-spinal fluid) shunting, around 80.5% of cases with idiopathic normal pressure hydrocephalus demonstrated enhanced and sustained cognitive function for at least 1 year post-operatively and our study revealed that younger age and less severe idiopathic normal pressure hydrocephalus led to a good long-term prognosis of cognitive function. Conclusions: Individuals with idiopathic normal pressure hydrocephalus experienced improved cognitive function 3-12 months after CSF shunt operation, with greater improvement seen in younger patients with milder illness. Therefore, early identification and appropriate treatment are crucial for long-term recovery and preservation of cognitive function in idiopathic normal pressure hydrocephalus. Early diagnosis of iNPH followed by CSF Shunt treatment can improve cognitive functions. Long-term evaluations of cognitive functions after V-P (ventriculo peritoneal) shunt operation are recommended.
VL  - 7
IS  - 3
ER  -

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Author Information

Mohamed Hamdy Ismail

Department of Neurology, Faculty of Medicine, Zagazig University, Zagazig, Egypt
Ahmed Ragab

Department of Neurosurgery, Faculty of Medicine, Zagazig University, Zagazig, Egypt
Hossam Mohamed Refat

Department of Neurology, Faculty of Medicine, Zagazig University, Zagazig, Egypt
Hassan Abaza

Department of Neurosurgery, Faculty of Medicine, Zagazig University, Zagazig, Egypt

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Plain Text BibTeX RIS

APA Style

Mohamed Hamdy Ismail, Ahmed Ragab, Hossam Mohamed Refat, Hassan Abaza. (2023). Cognitive Functions in Patients with Idiopathic Normal Pressure Hydrocephalus Before and After Ventriculoperitoneal Shunt. Clinical Neurology and Neuroscience, 7(3), 51-55. https://doi.org/10.11648/j.cnn.20230703.12

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ACS Style

Mohamed Hamdy Ismail; Ahmed Ragab; Hossam Mohamed Refat; Hassan Abaza. Cognitive Functions in Patients with Idiopathic Normal Pressure Hydrocephalus Before and After Ventriculoperitoneal Shunt. Clin. Neurol. Neurosci. 2023, 7(3), 51-55. doi: 10.11648/j.cnn.20230703.12

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AMA Style

Mohamed Hamdy Ismail, Ahmed Ragab, Hossam Mohamed Refat, Hassan Abaza. Cognitive Functions in Patients with Idiopathic Normal Pressure Hydrocephalus Before and After Ventriculoperitoneal Shunt. Clin Neurol Neurosci. 2023;7(3):51-55. doi: 10.11648/j.cnn.20230703.12

Copy | Download

@article{10.11648/j.cnn.20230703.12,
  author = {Mohamed Hamdy Ismail and Ahmed Ragab and Hossam Mohamed Refat and Hassan Abaza},
  title = {Cognitive Functions in Patients with Idiopathic Normal Pressure Hydrocephalus Before and After Ventriculoperitoneal Shunt},
  journal = {Clinical Neurology and Neuroscience},
  volume = {7},
  number = {3},
  pages = {51-55},
  doi = {10.11648/j.cnn.20230703.12},
  url = {https://doi.org/10.11648/j.cnn.20230703.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cnn.20230703.12},
  abstract = {Background: Clinical manifestations of idiopathic normal pressure hydrocephalus [iNPH] involve dementia, urinary incontinence and gait disturbance. Idiopathic normal pressure hydrocephalus treatment for short- and long-term improvement and maintenance of gait and also cognitive function is essential for reducing the caregiving burden on families and society. Methods: this study was done on 41participants with a diagnosis of iNPH, subjected to detailed medical and neurological history taking and neuropsychological assessment for cognitive functions before and after ventriculoperitoneal shunt operation. Results: After CSF (cerebro-spinal fluid) shunting, around 80.5% of cases with idiopathic normal pressure hydrocephalus demonstrated enhanced and sustained cognitive function for at least 1 year post-operatively and our study revealed that younger age and less severe idiopathic normal pressure hydrocephalus led to a good long-term prognosis of cognitive function. Conclusions: Individuals with idiopathic normal pressure hydrocephalus experienced improved cognitive function 3-12 months after CSF shunt operation, with greater improvement seen in younger patients with milder illness. Therefore, early identification and appropriate treatment are crucial for long-term recovery and preservation of cognitive function in idiopathic normal pressure hydrocephalus. Early diagnosis of iNPH followed by CSF Shunt treatment can improve cognitive functions. Long-term evaluations of cognitive functions after V-P (ventriculo peritoneal) shunt operation are recommended.},
 year = {2023}
}

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TY  - JOUR
T1  - Cognitive Functions in Patients with Idiopathic Normal Pressure Hydrocephalus Before and After Ventriculoperitoneal Shunt
AU  - Mohamed Hamdy Ismail
AU  - Ahmed Ragab
AU  - Hossam Mohamed Refat
AU  - Hassan Abaza
Y1  - 2023/09/25
PY  - 2023
N1  - https://doi.org/10.11648/j.cnn.20230703.12
DO  - 10.11648/j.cnn.20230703.12
T2  - Clinical Neurology and Neuroscience
JF  - Clinical Neurology and Neuroscience
JO  - Clinical Neurology and Neuroscience
SP  - 51
EP  - 55
PB  - Science Publishing Group
SN  - 2578-8930
UR  - https://doi.org/10.11648/j.cnn.20230703.12
AB  - Background: Clinical manifestations of idiopathic normal pressure hydrocephalus [iNPH] involve dementia, urinary incontinence and gait disturbance. Idiopathic normal pressure hydrocephalus treatment for short- and long-term improvement and maintenance of gait and also cognitive function is essential for reducing the caregiving burden on families and society. Methods: this study was done on 41participants with a diagnosis of iNPH, subjected to detailed medical and neurological history taking and neuropsychological assessment for cognitive functions before and after ventriculoperitoneal shunt operation. Results: After CSF (cerebro-spinal fluid) shunting, around 80.5% of cases with idiopathic normal pressure hydrocephalus demonstrated enhanced and sustained cognitive function for at least 1 year post-operatively and our study revealed that younger age and less severe idiopathic normal pressure hydrocephalus led to a good long-term prognosis of cognitive function. Conclusions: Individuals with idiopathic normal pressure hydrocephalus experienced improved cognitive function 3-12 months after CSF shunt operation, with greater improvement seen in younger patients with milder illness. Therefore, early identification and appropriate treatment are crucial for long-term recovery and preservation of cognitive function in idiopathic normal pressure hydrocephalus. Early diagnosis of iNPH followed by CSF Shunt treatment can improve cognitive functions. Long-term evaluations of cognitive functions after V-P (ventriculo peritoneal) shunt operation are recommended.
VL  - 7
IS  - 3
ER  -

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