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The Study of Antimicrobial Activities of Various Transition Metal Mixed Ligand Complexes Containing 1,10-Phenanthroline with Any Other Ligands

Received: 1 February 2022    Accepted: 24 February 2022    Published: 28 February 2022
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Abstract

The widespread usage of antibiotics in recent years has resulted in a surge in drug‑resistant bacteria resistant to a variety of medications. The identification of innovative and potent molecules against new targets is critical to combating the worrisome problem of microbial resistance to antibiotics. Numerous transition metal mixed ligand complexes have been explored as a result of this, with promising results. Because transition metals have different oxidation states and can interact with a variety of ligands, they play an essential role in medical inorganic chemistry. Metals' high activity has led to the recent creation of metal‑based pharmaceuticals that are being explored as viable candidates for pharmacological and therapeutic purposes. This review focuses on research conducted over the last few decades that has sought to possess biological applications such as antimicrobial, antifungal, and antibacterial activities of synthetic mixed ligand transition metal complexes, and it focuses primarily on a small number of transition metal mixed ligand complexes such as Mn (II), Co(II), Cu(II), and Zn(II), Ru(III) that contain 1,10-Phenanthroline as a major ligand The majority of this article is devoted to nitrogen donor ligands that chelate transition metals and are employed in metallodrugs.

Published in International Journal of Bioorganic Chemistry (Volume 7, Issue 1)
DOI 10.11648/j.ijbc.20220701.11
Page(s) 1-10
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

1,10-phenanthriline, Mixed Ligand Complexes, Biological Activities

References
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    Aklilu Melese Mengesha. (2022). The Study of Antimicrobial Activities of Various Transition Metal Mixed Ligand Complexes Containing 1,10-Phenanthroline with Any Other Ligands. International Journal of Bioorganic Chemistry, 7(1), 1-10. https://doi.org/10.11648/j.ijbc.20220701.11

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    Aklilu Melese Mengesha. The Study of Antimicrobial Activities of Various Transition Metal Mixed Ligand Complexes Containing 1,10-Phenanthroline with Any Other Ligands. Int. J. Bioorg. Chem. 2022, 7(1), 1-10. doi: 10.11648/j.ijbc.20220701.11

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    AMA Style

    Aklilu Melese Mengesha. The Study of Antimicrobial Activities of Various Transition Metal Mixed Ligand Complexes Containing 1,10-Phenanthroline with Any Other Ligands. Int J Bioorg Chem. 2022;7(1):1-10. doi: 10.11648/j.ijbc.20220701.11

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  • @article{10.11648/j.ijbc.20220701.11,
      author = {Aklilu Melese Mengesha},
      title = {The Study of Antimicrobial Activities of Various Transition Metal Mixed Ligand Complexes Containing 1,10-Phenanthroline with Any Other Ligands},
      journal = {International Journal of Bioorganic Chemistry},
      volume = {7},
      number = {1},
      pages = {1-10},
      doi = {10.11648/j.ijbc.20220701.11},
      url = {https://doi.org/10.11648/j.ijbc.20220701.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbc.20220701.11},
      abstract = {The widespread usage of antibiotics in recent years has resulted in a surge in drug‑resistant bacteria resistant to a variety of medications. The identification of innovative and potent molecules against new targets is critical to combating the worrisome problem of microbial resistance to antibiotics. Numerous transition metal mixed ligand complexes have been explored as a result of this, with promising results. Because transition metals have different oxidation states and can interact with a variety of ligands, they play an essential role in medical inorganic chemistry. Metals' high activity has led to the recent creation of metal‑based pharmaceuticals that are being explored as viable candidates for pharmacological and therapeutic purposes. This review focuses on research conducted over the last few decades that has sought to possess biological applications such as antimicrobial, antifungal, and antibacterial activities of synthetic mixed ligand transition metal complexes, and it focuses primarily on a small number of transition metal mixed ligand complexes such as Mn (II), Co(II), Cu(II), and Zn(II), Ru(III) that contain 1,10-Phenanthroline as a major ligand The majority of this article is devoted to nitrogen donor ligands that chelate transition metals and are employed in metallodrugs.},
     year = {2022}
    }
    

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    AU  - Aklilu Melese Mengesha
    Y1  - 2022/02/28
    PY  - 2022
    N1  - https://doi.org/10.11648/j.ijbc.20220701.11
    DO  - 10.11648/j.ijbc.20220701.11
    T2  - International Journal of Bioorganic Chemistry
    JF  - International Journal of Bioorganic Chemistry
    JO  - International Journal of Bioorganic Chemistry
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    PB  - Science Publishing Group
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    UR  - https://doi.org/10.11648/j.ijbc.20220701.11
    AB  - The widespread usage of antibiotics in recent years has resulted in a surge in drug‑resistant bacteria resistant to a variety of medications. The identification of innovative and potent molecules against new targets is critical to combating the worrisome problem of microbial resistance to antibiotics. Numerous transition metal mixed ligand complexes have been explored as a result of this, with promising results. Because transition metals have different oxidation states and can interact with a variety of ligands, they play an essential role in medical inorganic chemistry. Metals' high activity has led to the recent creation of metal‑based pharmaceuticals that are being explored as viable candidates for pharmacological and therapeutic purposes. This review focuses on research conducted over the last few decades that has sought to possess biological applications such as antimicrobial, antifungal, and antibacterial activities of synthetic mixed ligand transition metal complexes, and it focuses primarily on a small number of transition metal mixed ligand complexes such as Mn (II), Co(II), Cu(II), and Zn(II), Ru(III) that contain 1,10-Phenanthroline as a major ligand The majority of this article is devoted to nitrogen donor ligands that chelate transition metals and are employed in metallodrugs.
    VL  - 7
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Author Information
  • Department of Chemistry, College of Natural and Computational Sciences, Kebridehar University, Kebridehar, Ethiopia

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