Background: Transient tachypnea of the newborn (TTNB) is a common cause of respiratory distress in late preterm and full-term infants. It is caused by a delay in the clearance of fetal lung fluids. Although TTNB is a self-limited condition, prophylactic antibiotics usually administered for 48-72 hours until negative blood culture is reported. Objective: In this study, we aim to identify the relationship between using prophylactic antibiotics and the duration of tachypnea and hospitalization in neonates with TTNB. Materials and Methods: this was a cohort study design included 102 infants with TTNB. The infants were divided into two groups, one received supportive care, and the other received supportive care with intravenous antibiotics. The clinical signs and laboratory results were examined in the two groups. Results: Of total 102 infants who were included in this study, 41 (40.2%) were received supportive care with prophylactic intravenous antibiotics. There were no significant differences between two groups in terms of gender, gestational age, birth weight, mode of delivery, and white blood cell. A significant relation was found between receiving prophylactic antibiotics with the duration of tachypnea and hospitalization. Conclusions: In the recent study, we found an increase in the hospitalization and tachypnea period in the group received antibiotics.
| Published in | Journal of Drug Design and Medicinal Chemistry (Volume 7, Issue 1) |
| DOI | 10.11648/j.jddmc.20210701.11 |
| Page(s) | 1-4 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Transient Tachypnea of the Newborn, Prophylactic Antibiotics, Duration of Tachypnea, Duration of Hospitalization
| [1] | Avery, M. E; Gatewood, O. B; Brumley, G. Transient tachypnea of newborn. Possible delayed resorption of fluid at birth. Am J Dis Child 1966; 111: 380. |
| [2] | Hamdoon, G. W. Risk factors for development of transient tachypnea of newborns. Annals of the College of Medicine Mosul 2018; 40, no. 1: 15-19. |
| [3] | Morrison, J. J; Rennie, J. M; Milton, P. J. Neonatal respiratory morbidity and mode of delivery at term: influence of timing of elective caesarean section. Br J Obstet Gynaecol 1995; 102: 101. |
| [4] | Aathi, M. K. "Transient Tachypnea of Newborn (TTN): An Overview." Int J Nur Edu Res 2014; 2, no. 2: 99-103. |
| [5] | Morioka, I; Yamana, K; Kurokawa, D. How long is transient tachypnea of the newborn dependent on oxygen supplementation? Pediatr Int 2015; 57: 1054–1055. |
| [6] | Hagen, E; Chu, A; Lew, Ch. Transient Tachypnea of the Newborn. American Academy of Pediatrics 2017; 18 (3): 141-148. |
| [7] | Abughalwa, M; Taha, S; Sharaf, N; Salama, H. Antibiotics therapy in classic transient tachypnea of the newborn: A necessary treatment or not ? A prospective study. Neonatology Today 2012; 7. |
| [8] | Leibovici, L; Paul, M; Garner, P; Sinclair, D. J; Afshari, A; Pace, N. L. Addressing resistance to antibiotics in systematic reviews of antibiotic interventions. The Journal of Antimicrobial Chemotherapy 2016; 71 (9): 2367–9. |
| [9] | Bromberger, P; Lawrence, J. M; Braun, D; Saunders, B; Contreras, R; Pettiti, D. B. The influence of intrapartum antibiotics on the clinical spectrum of early-onset group B streptococcal infection in term infants. Pediatrics 2000; 106: 244-50. |
| [10] | Zhang, S; Chan, D. Facing a new challenge; the adverse effects of antibiotics on gut microbiota and host immunity. Chin Med J 2019; 132 (10) 1135-1138. |
| [11] | Cipolla, D; Giuffrè, M; Mammina, C; Corsello, G. Prevention of nosocomial infections and surveillance of emerging resistances in NICU. The Journal of Maternal-Fetal & Neonatal Medicine 2011; 24 (sup1): 23-6. |
| [12] | Yurdakok, M; Ozek, E. Transient tachypnea of the newborn: the treatment strategies. Current pharmaceutical design 2012; 18 (21): 3046-9. |
| [13] | Tripathi, N; Cotten, C. M; Smith, P. B. Antibiotic use and misuse in the neonatal intensive care unit. Clin Perinatol 2012; 39 (1): 61–68. doi: 10.1016/j.clp.2011.12.003. |
| [14] | Sabzehei, M. K; Basiri, B; Shokouhi, M; Poorolajal, J; & Bahadorbeigi, L. Evaluating the Need for Prophylactic Antibiotic Therapy in Infants with Transient Tachypnea of the Newborn: A Triple-Blind Randomized Clinical Trial Study. International Journal of Pediatrics2018; 6 (8), 8086-8092. |
| [15] | Yarci, E; Asihan, K. C; Fuat, E. C. "Antibiotics for transient tachypnea of newborn; are comorbidities reasons or results?" Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi 2019; 17, no. 1: 254-257. |
| [16] | Dehdashtian, M; Aletayeb, M; Malakian, A; Aramesh, M. R, & Malvandi, H. Clinical course in infants diagnosed with transient tachypnea of newborn: A clinical trial assessing the role of conservative versus conventional management. Journal of the Chinese Medical Association 2018; 81 (2), 183-186. |
| [17] | Weintraub, A. S; Cadet, C. T; Perez, R; DeLorenzo, E; Holzman, I. R; Stroustrup, A. Antibiotic use in newborns with transient tachypnea of the newborn. Neonatology 2013; 103 (3): 235–240. doi: 10. 1159/000346057. |
| [18] | Li, J; Wu, J; Du, L; Hu, Y; Yang, X; Mu, D; Xia, B. Different antibiotic strategies in transient tachypnea of the newborn: an ambispective cohort study. Eur J Pediatr 2015; 174 (9): 1217-23. |
APA Style
Dalal Saadoun, Leen Doya, Adnan Dayoub, Oday Jouni. (2021). Transient Tachypnea of the Newborn and the Use of Prophylactic Antibiotics. Journal of Drug Design and Medicinal Chemistry, 7(1), 1-4. https://doi.org/10.11648/j.jddmc.20210701.11
ACS Style
Dalal Saadoun; Leen Doya; Adnan Dayoub; Oday Jouni. Transient Tachypnea of the Newborn and the Use of Prophylactic Antibiotics. J. Drug Des. Med. Chem. 2021, 7(1), 1-4. doi: 10.11648/j.jddmc.20210701.11
AMA Style
Dalal Saadoun, Leen Doya, Adnan Dayoub, Oday Jouni. Transient Tachypnea of the Newborn and the Use of Prophylactic Antibiotics. J Drug Des Med Chem. 2021;7(1):1-4. doi: 10.11648/j.jddmc.20210701.11
Share This Article
Twitter
Linked In
Facebook
Copy
Download@article{10.11648/j.jddmc.20210701.11,
author = {Dalal Saadoun and Leen Doya and Adnan Dayoub and Oday Jouni},
title = {Transient Tachypnea of the Newborn and the Use of Prophylactic Antibiotics},
journal = {Journal of Drug Design and Medicinal Chemistry},
volume = {7},
number = {1},
pages = {1-4},
doi = {10.11648/j.jddmc.20210701.11},
url = {https://doi.org/10.11648/j.jddmc.20210701.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jddmc.20210701.11},
abstract = {Background: Transient tachypnea of the newborn (TTNB) is a common cause of respiratory distress in late preterm and full-term infants. It is caused by a delay in the clearance of fetal lung fluids. Although TTNB is a self-limited condition, prophylactic antibiotics usually administered for 48-72 hours until negative blood culture is reported. Objective: In this study, we aim to identify the relationship between using prophylactic antibiotics and the duration of tachypnea and hospitalization in neonates with TTNB. Materials and Methods: this was a cohort study design included 102 infants with TTNB. The infants were divided into two groups, one received supportive care, and the other received supportive care with intravenous antibiotics. The clinical signs and laboratory results were examined in the two groups. Results: Of total 102 infants who were included in this study, 41 (40.2%) were received supportive care with prophylactic intravenous antibiotics. There were no significant differences between two groups in terms of gender, gestational age, birth weight, mode of delivery, and white blood cell. A significant relation was found between receiving prophylactic antibiotics with the duration of tachypnea and hospitalization. Conclusions: In the recent study, we found an increase in the hospitalization and tachypnea period in the group received antibiotics.},
year = {2021}
}
TY - JOUR T1 - Transient Tachypnea of the Newborn and the Use of Prophylactic Antibiotics AU - Dalal Saadoun AU - Leen Doya AU - Adnan Dayoub AU - Oday Jouni Y1 - 2021/01/22 PY - 2021 N1 - https://doi.org/10.11648/j.jddmc.20210701.11 DO - 10.11648/j.jddmc.20210701.11 T2 - Journal of Drug Design and Medicinal Chemistry JF - Journal of Drug Design and Medicinal Chemistry JO - Journal of Drug Design and Medicinal Chemistry SP - 1 EP - 4 PB - Science Publishing Group SN - 2472-3576 UR - https://doi.org/10.11648/j.jddmc.20210701.11 AB - Background: Transient tachypnea of the newborn (TTNB) is a common cause of respiratory distress in late preterm and full-term infants. It is caused by a delay in the clearance of fetal lung fluids. Although TTNB is a self-limited condition, prophylactic antibiotics usually administered for 48-72 hours until negative blood culture is reported. Objective: In this study, we aim to identify the relationship between using prophylactic antibiotics and the duration of tachypnea and hospitalization in neonates with TTNB. Materials and Methods: this was a cohort study design included 102 infants with TTNB. The infants were divided into two groups, one received supportive care, and the other received supportive care with intravenous antibiotics. The clinical signs and laboratory results were examined in the two groups. Results: Of total 102 infants who were included in this study, 41 (40.2%) were received supportive care with prophylactic intravenous antibiotics. There were no significant differences between two groups in terms of gender, gestational age, birth weight, mode of delivery, and white blood cell. A significant relation was found between receiving prophylactic antibiotics with the duration of tachypnea and hospitalization. Conclusions: In the recent study, we found an increase in the hospitalization and tachypnea period in the group received antibiotics. VL - 7 IS - 1 ER -
Information
Email: