The plant Bombax buonopozense is a large tropical tree that grows up to 40 meters. Scattered in the dry and rain forest, widely distributed in African countries such as Ghana, Nigeria, Sierra Leone, Uganda, Liberia, Gabon, and different parts are used for different ailments. The study targets phytochemical screening, antimicrobial and anti-inflammatory activities of the plant leaf to substantiate some of its ethno-medicinal uses. The phytochemical composition was evaluated using standard procedures and the antimicrobial activity of the extracts using the agar diffusion method on the following clinical isolates: (Staphylococcus aureus (ATCC 29213), Streptococcus faecials, Bacillus subtilis (ATCC 8263), Escherichia coli (ATCC 25922), Salmonella tiphi, Pseudomonas aeruginosa (ATCC 27853), Candida albican (ATCC 90029), Aspergillus niger and Phytophera megakarya. Anti-inflammatory activity was also evaluated using carrageenan-induced oedema of the rat paw. Phytochemical screening revealed the presence of saponins, tannins, flavonoids, carbohydrates, terpenoids, anthraquinone, steroids, reducing sugar, phenols, alkaloids, and phlobatannins. The leaf extract had strong activity on Strep. faecalis, E. coli, P. Aeruginosa and moderate to little activity on the rest of test organisms. The leaf extract suppressed the onset of inflammatory but did not sustain it till 3rd h compared to reference drug (Diclofenac). The findings indicate leaf extract contain some bioactive compounds which may be used for possible treatment of microbial infections and oxidative stress related diseases which justify its ethno-medicinal uses.
| Published in | Journal of Diseases and Medicinal Plants (Volume 8, Issue 3) |
| DOI | 10.11648/j.jdmp.20220803.13 |
| Page(s) | 61-65 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Bombax buonopozense, Phytochemical, Antimicrobial, Anti-inflammatory
| [1] | Okwu, D. E., Ekeke, O. (2003). Phytochemical Screening and Mineral composition of chewing sticks in South Eastern Nigeria. Global Journal Pure and Applied Science; 9: 235-238. |
| [2] | Beentje, H. and Sara, S. (2001). Plant systemic and phytogeography for the understanding of African Biodiversity. Systemics and Geography of plants. 71, 284-6. |
| [3] | Dubost, G. (1984). Comparison of diets of frugivorous forest mammals of Gabon. J. Mammalogy. 65: 298- 316. |
| [4] | Trease, G. E., Evans, W. C. (1989). Pharmacognosy 13th ed. Bailliere Tindall, London, 176-80. |
| [5] | Valgas, C., De Souza, S. M., Smania, E. F. A. and Smania, A. Jr. (2007). Screening methods to determine antibacterial activity of natural products. Braz. J. Microbiol. 38 (2), 378-381. |
| [6] | CLSI. (2012). Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow aerobically, approved standard - 9th ed. CLSI documents MO7-A9. Clinical and Laboratory Standard Institute. Wayne, P. A., 24-35. |
| [7] | Winter, C. A., Risley, E. A., and Nuss, G. W. (1962). Carrageenan-induced oedema in hind paw of the rat as an assay for anti-inflammatory drugs. Proceedings of society for experimental Biology and Medicine, 11, 544-547. |
| [8] | Akuodor, G. C., Essien, A. D., Ibrahim, J. A., Bassey, A., Akpan, J. L., Ikoro, N. C., Onyewejo, S. C. (2011a). Phytochemical and antimicrobial properties of the methanolic extracts of Bombax buonopozense leaf and root, Asian J. Med. Sc., 2: 190-194. |
| [9] | Cowan, M. M. (1999). Plant products as antimicrobial agents. Clin. Microbiol. Rev. 12: 564-582. |
| [10] | Esimone, C. O., Ebebe, I. M., Chah, K. E., Onyeka, C. G. (2003). Comparative antimicrobial effects of Psidium gujava. Journal of Trop. Med. Plants. 4, 185-189. |
| [11] | Adejumobi, A. J., Ogundiya, M. O., kolapo, K. A., Okunade, M. B. (2008). Phytochemical composition and in vitro antimicrobial activity of Anogeissus leiocarpus on some common oral pathogens. Journal of Med. Plants Res., 2: 193-196. |
| [12] | Onwuliri, F. C. and Wonang, D. L. (2004). Biochemical and antimicrobial studies of Zingiber offcinale and Allium sativum on slectected microorganisms. BSc. Project in the Department of Botany, University of Jos, Nigeria, p. 59. |
| [13] | Francis, G., Zohar, K., Harrinde, P. S. and Klans, S. B, (2002). The Biological Action of Saponins in Animal System; A review, Brit. J. Nutri., 88: 587-605. |
| [14] | Westendarp, H. (2006). Effects of tannins in animal nutition. Ditsch Tierarztl Wochenschr. 113 (7): 264-268. |
| [15] | Asuquo, O. R., Fisher C. E., Mesembe, O. E., Igiri, A. O., Ekom, J. I. (2013). Comparative study of aqueous and ethanolic leaf extracts of Spondias mombin on neurobehaviour in male rats. J. Pharm. Biol. Sci. 5: 29-35. |
| [16] | Quilan, P. T. (2000). The acute physiological and mood effect of tea and coffee. The role of caffeine level. Pharmacol. Biochem Behav., 66 (1): 19-28. |
| [17] | Okigbo, R. N. and Mmeka, E. C. (2006). An appraisal of phytomedicine in Africa. KMITL Sc. Technol. J. 6 (2): 83-93. |
| [18] | Usman, H. and Osuji, J. C. (2007). Phytochemical and in-vitro assay of the leaf extract o new bouldia leavis. Afr J Tad CAM, 4 (4): 476-480. |
| [19] | Lee, J. H., Park, K. H., Lee, M. H., Kim, H. T., Seo, W. D., Kim, W. D. (2013). Identification, characterization, and quantification of phenolic compounds in the antioxidant activity containing fraction from the seeds of Korean perilla (Perilla frutescens) cultivars. Food Chem. 136: 843-53. |
| [20] | Arvind J. Mungole, Ravi Awati, Alka Chaturvedi, Prakash Zanwar (2010). Preliminary Phytochemical screening of ipomoea obscura (L)-A hepatoprotective medicinal plant, Int J PharmTech Res. 2: 2307-12. |
| [21] | Derwich, E., Benziane, Z., Boukir, A. (2010). Chemical composition of leaf essential oil of Juniperus phoenicea and evaluation of its antibacterial activity, Int J Agric Biol. 12: 199-204. |
| [22] | Abdul Hafez, Upendra Jain, Pinky Sojwan, Sirish, Srivastava, A. Thakur (2013). Evaluation of carrageenan induced anti-inflammatory activity of ethanolic extract of bark of Ficus virens Linn in Swiss albino mice. Journal of phytopharmacology, 2 (3), 39-43. |
| [23] | Muralidhar, A., Sainathreddy, C., Someswara, Yadav, A. (2013). Anti-inflammatory studies of Barringtonia acutangula (Linn) fruits on wistar rats. International journal of phytomedicines, 5, 350-355. |
| [24] | Phadke, K. (1998). In vivo and in vitro models for arthritis, Indan Drugs, 25, 354-365. |
| [25] | Adams, M. R. and Moss, M. (1999). The Royal Society of Chemistry, Cambridge. Food Microbiology, 181-186. |
| [26] | Cheesbrough, M. (2000). Medical Laboratory Manual for Tropical Countries. Microbiology, Linacre House, Jordan Hill Oxford, 260. |
| [27] | Parekh, J. and Chanda, S. (2007). In vitro screening of antibacterial activity of aqueous and alcoholic extracts of various Indian Plants species against selected pathogens from Enterbacteriaceae. Afr. J. Microbiol. Res., 1 (6): 92-99. |
| [28] | Dorman, H. J. D. and Deans, S. G. (2000). Antimicrobial agents from plants: antibacterial activity of plant volatile oils. J. Appl. Microbiol. 88: 308-16. |
| [29] | Akuodor, G. C., Muazzam, I., Idris-Usman, M., Megwas, U. A., Akpan, J. L., Chilaka, K. C., Okoroafor, D. O., Osunkwo, U. A. (2011b). Evaluation of the antidiarrhoeal activity of methanol leaf extract of Bombax buonopozense. Ibnosina J. Med. Biomed. Sci., 3 (1): 15-20. |
| [30] | Akuodor, G. C., Idris-Usman, M., Ibrahim, J. A., Chilaka, K. C., Akpan, J. L., Dzarma, S., Muazzam, I. and Osunkwo, U. A. (2011c). Anti-nociceptic, anti-inflammatory and antipyretic effects of the methanolic extract of Bombax buonopozense leaves in rats and mice. Afr. J. Biotech. 10 (16): 3191-3196. |
| [31] | Akuodor, G. C., Mbah, C. C., Megwas, U. A., Ikoro, N. C., Akpan, J. L., Okwuosa, B. O., Osunkwo, U. A. (2011d). In vivo antimalarial activity of methanolic leaf extract of Bombax buonopozense in mice infected with plasmodium berghei. Int. J. Biol. Chem. Sci., 5 (5): 1790-1796. |
APA Style
Moruf Ademola Yusuf-Babatunde, Lateef Saka Kasim, Thomas Oyebode Idowu. (2022). Phytochemical Screening, Antimicrobial and Anti-inflammatory Activities of Ethanolic Extracts of the Leaf of Bombax buonopozense P. Beauv. (Bombacaceae). Journal of Diseases and Medicinal Plants, 8(3), 61-65. https://doi.org/10.11648/j.jdmp.20220803.13
ACS Style
Moruf Ademola Yusuf-Babatunde; Lateef Saka Kasim; Thomas Oyebode Idowu. Phytochemical Screening, Antimicrobial and Anti-inflammatory Activities of Ethanolic Extracts of the Leaf of Bombax buonopozense P. Beauv. (Bombacaceae). J. Dis. Med. Plants 2022, 8(3), 61-65. doi: 10.11648/j.jdmp.20220803.13
AMA Style
Moruf Ademola Yusuf-Babatunde, Lateef Saka Kasim, Thomas Oyebode Idowu. Phytochemical Screening, Antimicrobial and Anti-inflammatory Activities of Ethanolic Extracts of the Leaf of Bombax buonopozense P. Beauv. (Bombacaceae). J Dis Med Plants. 2022;8(3):61-65. doi: 10.11648/j.jdmp.20220803.13
Share This Article
Twitter
Linked In
Facebook
Copy
Download@article{10.11648/j.jdmp.20220803.13,
author = {Moruf Ademola Yusuf-Babatunde and Lateef Saka Kasim and Thomas Oyebode Idowu},
title = {Phytochemical Screening, Antimicrobial and Anti-inflammatory Activities of Ethanolic Extracts of the Leaf of Bombax buonopozense P. Beauv. (Bombacaceae)},
journal = {Journal of Diseases and Medicinal Plants},
volume = {8},
number = {3},
pages = {61-65},
doi = {10.11648/j.jdmp.20220803.13},
url = {https://doi.org/10.11648/j.jdmp.20220803.13},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jdmp.20220803.13},
abstract = {The plant Bombax buonopozense is a large tropical tree that grows up to 40 meters. Scattered in the dry and rain forest, widely distributed in African countries such as Ghana, Nigeria, Sierra Leone, Uganda, Liberia, Gabon, and different parts are used for different ailments. The study targets phytochemical screening, antimicrobial and anti-inflammatory activities of the plant leaf to substantiate some of its ethno-medicinal uses. The phytochemical composition was evaluated using standard procedures and the antimicrobial activity of the extracts using the agar diffusion method on the following clinical isolates: (Staphylococcus aureus (ATCC 29213), Streptococcus faecials, Bacillus subtilis (ATCC 8263), Escherichia coli (ATCC 25922), Salmonella tiphi, Pseudomonas aeruginosa (ATCC 27853), Candida albican (ATCC 90029), Aspergillus niger and Phytophera megakarya. Anti-inflammatory activity was also evaluated using carrageenan-induced oedema of the rat paw. Phytochemical screening revealed the presence of saponins, tannins, flavonoids, carbohydrates, terpenoids, anthraquinone, steroids, reducing sugar, phenols, alkaloids, and phlobatannins. The leaf extract had strong activity on Strep. faecalis, E. coli, P. Aeruginosa and moderate to little activity on the rest of test organisms. The leaf extract suppressed the onset of inflammatory but did not sustain it till 3rd h compared to reference drug (Diclofenac). The findings indicate leaf extract contain some bioactive compounds which may be used for possible treatment of microbial infections and oxidative stress related diseases which justify its ethno-medicinal uses.},
year = {2022}
}
TY - JOUR T1 - Phytochemical Screening, Antimicrobial and Anti-inflammatory Activities of Ethanolic Extracts of the Leaf of Bombax buonopozense P. Beauv. (Bombacaceae) AU - Moruf Ademola Yusuf-Babatunde AU - Lateef Saka Kasim AU - Thomas Oyebode Idowu Y1 - 2022/09/29 PY - 2022 N1 - https://doi.org/10.11648/j.jdmp.20220803.13 DO - 10.11648/j.jdmp.20220803.13 T2 - Journal of Diseases and Medicinal Plants JF - Journal of Diseases and Medicinal Plants JO - Journal of Diseases and Medicinal Plants SP - 61 EP - 65 PB - Science Publishing Group SN - 2469-8210 UR - https://doi.org/10.11648/j.jdmp.20220803.13 AB - The plant Bombax buonopozense is a large tropical tree that grows up to 40 meters. Scattered in the dry and rain forest, widely distributed in African countries such as Ghana, Nigeria, Sierra Leone, Uganda, Liberia, Gabon, and different parts are used for different ailments. The study targets phytochemical screening, antimicrobial and anti-inflammatory activities of the plant leaf to substantiate some of its ethno-medicinal uses. The phytochemical composition was evaluated using standard procedures and the antimicrobial activity of the extracts using the agar diffusion method on the following clinical isolates: (Staphylococcus aureus (ATCC 29213), Streptococcus faecials, Bacillus subtilis (ATCC 8263), Escherichia coli (ATCC 25922), Salmonella tiphi, Pseudomonas aeruginosa (ATCC 27853), Candida albican (ATCC 90029), Aspergillus niger and Phytophera megakarya. Anti-inflammatory activity was also evaluated using carrageenan-induced oedema of the rat paw. Phytochemical screening revealed the presence of saponins, tannins, flavonoids, carbohydrates, terpenoids, anthraquinone, steroids, reducing sugar, phenols, alkaloids, and phlobatannins. The leaf extract had strong activity on Strep. faecalis, E. coli, P. Aeruginosa and moderate to little activity on the rest of test organisms. The leaf extract suppressed the onset of inflammatory but did not sustain it till 3rd h compared to reference drug (Diclofenac). The findings indicate leaf extract contain some bioactive compounds which may be used for possible treatment of microbial infections and oxidative stress related diseases which justify its ethno-medicinal uses. VL - 8 IS - 3 ER -
Information
Email: