Evaluation of Biological Parameters of Diabetic Patients Treated with Medicinal Plants: Case of the City of N'Djamena

Elise Dagosse; Memti Mberdoum Nguinambaye; Nadjioroum Ngam Asra; Brahim Boy Otchom

doi:doi:10.11648/j.jdmp.20220804.11

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Evaluation of Biological Parameters of Diabetic Patients Treated with Medicinal Plants: Case of the City of N'Djamena

Elise Dagosse, Memti Mberdoum Nguinambaye, Nadjioroum Ngam Asra, Brahim Boy Otchom

Published in Journal of Diseases and Medicinal Plants (Volume 8, Issue 4)

Received: 8 October 2022 Accepted: 27 October 2022 Published: 10 November 2022

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Abstract

Diabetes is a metabolic disorder related to the secretion and / or absorption of insulin by the body, it is characterized mainly by a high level of glucose in the blood beyond 1.10 g / l. The objective of this study is to contribute to the development of medicinal plants that can help in the management of diabetes mellitus. The data collected during this study were done through a direct interview on the basis of an ethnobotanical survey form. The data of the study were analyzed on Excel and then SPSS version 22.0. Blood samples of 30 diabetic patients of both sexes subjected to plant-based treatments were collected. The different assays were performed at time 0 and 8 weeks after the first sample. The average age of the patients was 44.13 years with extremes of 18 and 70 years and a male predominance at 56%. Twenty-three medicinal plants were identified, 6 of which were used in the composition of three recipes for diabetic patients. The recipe composed of Leptadenia hastata + Guiera senegalensis had a 100% favorable effect on the carbohydrate parameters. On the other hand, the recipe composed of Boscia senegalensis+Anogeissus leiocarpus+Guiera senegalensis and the one composed of Prosopis africana+ Indigofera astragalana + Guiera senegalensis had a 57.1% and 55.6% favorable effect respectively on the carbohydrate parameters by restoring the glycemic balance All these 3 recipes had no toxic effect on the liver and kidneys: transaminases and creatine remained stable. A phytochemical and pharmacological study on animals with these plants will allow the development of phytomedicines against diabetes.

Published in	Journal of Diseases and Medicinal Plants (Volume 8, Issue 4)
DOI	10.11648/j.jdmp.20220804.11
Page(s)	66-73
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Medicinal Plants, Diabetic Patients, N'Djamena, Chad

References

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[11]	Oksom S. JB, 2010. Pharmacological evaluation of Gardenia ternifolia and Hymenocardia acida extracts, plants with antidiabetic activation. DEA of Pharmacology, University of Lome, 61p.
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[19]	Alia Telli, Marie-Andrée Esnault et Aminata Ould El Hadj Khelil. An ethnopharmacological survey of plants used in traditional diabetes treatment in south-eastern Algeria (Ouargla province). Journal of Arid Environments 2013; 127: 82-92.
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APA Style

Elise Dagosse, Memti Mberdoum Nguinambaye, Nadjioroum Ngam Asra, Brahim Boy Otchom. (2022). Evaluation of Biological Parameters of Diabetic Patients Treated with Medicinal Plants: Case of the City of N'Djamena. Journal of Diseases and Medicinal Plants, 8(4), 66-73. https://doi.org/10.11648/j.jdmp.20220804.11

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ACS Style

Elise Dagosse; Memti Mberdoum Nguinambaye; Nadjioroum Ngam Asra; Brahim Boy Otchom. Evaluation of Biological Parameters of Diabetic Patients Treated with Medicinal Plants: Case of the City of N'Djamena. J. Dis. Med. Plants 2022, 8(4), 66-73. doi: 10.11648/j.jdmp.20220804.11

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AMA Style

Elise Dagosse, Memti Mberdoum Nguinambaye, Nadjioroum Ngam Asra, Brahim Boy Otchom. Evaluation of Biological Parameters of Diabetic Patients Treated with Medicinal Plants: Case of the City of N'Djamena. J Dis Med Plants. 2022;8(4):66-73. doi: 10.11648/j.jdmp.20220804.11

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@article{10.11648/j.jdmp.20220804.11,
  author = {Elise Dagosse and Memti Mberdoum Nguinambaye and Nadjioroum Ngam Asra and Brahim Boy Otchom},
  title = {Evaluation of Biological Parameters of Diabetic Patients Treated with Medicinal Plants: Case of the City of N'Djamena},
  journal = {Journal of Diseases and Medicinal Plants},
  volume = {8},
  number = {4},
  pages = {66-73},
  doi = {10.11648/j.jdmp.20220804.11},
  url = {https://doi.org/10.11648/j.jdmp.20220804.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jdmp.20220804.11},
  abstract = {Diabetes is a metabolic disorder related to the secretion and / or absorption of insulin by the body, it is characterized mainly by a high level of glucose in the blood beyond 1.10 g / l. The objective of this study is to contribute to the development of medicinal plants that can help in the management of diabetes mellitus. The data collected during this study were done through a direct interview on the basis of an ethnobotanical survey form. The data of the study were analyzed on Excel and then SPSS version 22.0. Blood samples of 30 diabetic patients of both sexes subjected to plant-based treatments were collected. The different assays were performed at time 0 and 8 weeks after the first sample. The average age of the patients was 44.13 years with extremes of 18 and 70 years and a male predominance at 56%. Twenty-three medicinal plants were identified, 6 of which were used in the composition of three recipes for diabetic patients. The recipe composed of Leptadenia hastata + Guiera senegalensis had a 100% favorable effect on the carbohydrate parameters. On the other hand, the recipe composed of Boscia senegalensis+Anogeissus leiocarpus+Guiera senegalensis and the one composed of Prosopis africana+ Indigofera astragalana + Guiera senegalensis had a 57.1% and 55.6% favorable effect respectively on the carbohydrate parameters by restoring the glycemic balance All these 3 recipes had no toxic effect on the liver and kidneys: transaminases and creatine remained stable. A phytochemical and pharmacological study on animals with these plants will allow the development of phytomedicines against diabetes.},
 year = {2022}
}

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TY  - JOUR
T1  - Evaluation of Biological Parameters of Diabetic Patients Treated with Medicinal Plants: Case of the City of N'Djamena
AU  - Elise Dagosse
AU  - Memti Mberdoum Nguinambaye
AU  - Nadjioroum Ngam Asra
AU  - Brahim Boy Otchom
Y1  - 2022/11/10
PY  - 2022
N1  - https://doi.org/10.11648/j.jdmp.20220804.11
DO  - 10.11648/j.jdmp.20220804.11
T2  - Journal of Diseases and Medicinal Plants
JF  - Journal of Diseases and Medicinal Plants
JO  - Journal of Diseases and Medicinal Plants
SP  - 66
EP  - 73
PB  - Science Publishing Group
SN  - 2469-8210
UR  - https://doi.org/10.11648/j.jdmp.20220804.11
AB  - Diabetes is a metabolic disorder related to the secretion and / or absorption of insulin by the body, it is characterized mainly by a high level of glucose in the blood beyond 1.10 g / l. The objective of this study is to contribute to the development of medicinal plants that can help in the management of diabetes mellitus. The data collected during this study were done through a direct interview on the basis of an ethnobotanical survey form. The data of the study were analyzed on Excel and then SPSS version 22.0. Blood samples of 30 diabetic patients of both sexes subjected to plant-based treatments were collected. The different assays were performed at time 0 and 8 weeks after the first sample. The average age of the patients was 44.13 years with extremes of 18 and 70 years and a male predominance at 56%. Twenty-three medicinal plants were identified, 6 of which were used in the composition of three recipes for diabetic patients. The recipe composed of Leptadenia hastata + Guiera senegalensis had a 100% favorable effect on the carbohydrate parameters. On the other hand, the recipe composed of Boscia senegalensis+Anogeissus leiocarpus+Guiera senegalensis and the one composed of Prosopis africana+ Indigofera astragalana + Guiera senegalensis had a 57.1% and 55.6% favorable effect respectively on the carbohydrate parameters by restoring the glycemic balance All these 3 recipes had no toxic effect on the liver and kidneys: transaminases and creatine remained stable. A phytochemical and pharmacological study on animals with these plants will allow the development of phytomedicines against diabetes.
VL  - 8
IS  - 4
ER  -

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Author Information

Elise Dagosse

Department of Biomedical, Pharmaceutical, Nursing and Nutritional Sciences, University Touma?, N'Djamena, Chad
Memti Mberdoum Nguinambaye

Department of Biological Sciences, Faculty of Exact and Applied Sciences, University of N’Djamena, N’Djamena, Chad
Nadjioroum Ngam Asra

Department of Biomedical, Faculty of Human Health Sciences, University of N’Djamena, N'Djamena, Chad
Brahim Boy Otchom

Department of Biomedical, Pharmaceutical, Nursing and Nutritional Sciences, University Touma?, N'Djamena, Chad

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APA Style

Elise Dagosse, Memti Mberdoum Nguinambaye, Nadjioroum Ngam Asra, Brahim Boy Otchom. (2022). Evaluation of Biological Parameters of Diabetic Patients Treated with Medicinal Plants: Case of the City of N'Djamena. Journal of Diseases and Medicinal Plants, 8(4), 66-73. https://doi.org/10.11648/j.jdmp.20220804.11

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ACS Style

Elise Dagosse; Memti Mberdoum Nguinambaye; Nadjioroum Ngam Asra; Brahim Boy Otchom. Evaluation of Biological Parameters of Diabetic Patients Treated with Medicinal Plants: Case of the City of N'Djamena. J. Dis. Med. Plants 2022, 8(4), 66-73. doi: 10.11648/j.jdmp.20220804.11

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AMA Style

Elise Dagosse, Memti Mberdoum Nguinambaye, Nadjioroum Ngam Asra, Brahim Boy Otchom. Evaluation of Biological Parameters of Diabetic Patients Treated with Medicinal Plants: Case of the City of N'Djamena. J Dis Med Plants. 2022;8(4):66-73. doi: 10.11648/j.jdmp.20220804.11

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@article{10.11648/j.jdmp.20220804.11,
  author = {Elise Dagosse and Memti Mberdoum Nguinambaye and Nadjioroum Ngam Asra and Brahim Boy Otchom},
  title = {Evaluation of Biological Parameters of Diabetic Patients Treated with Medicinal Plants: Case of the City of N'Djamena},
  journal = {Journal of Diseases and Medicinal Plants},
  volume = {8},
  number = {4},
  pages = {66-73},
  doi = {10.11648/j.jdmp.20220804.11},
  url = {https://doi.org/10.11648/j.jdmp.20220804.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jdmp.20220804.11},
  abstract = {Diabetes is a metabolic disorder related to the secretion and / or absorption of insulin by the body, it is characterized mainly by a high level of glucose in the blood beyond 1.10 g / l. The objective of this study is to contribute to the development of medicinal plants that can help in the management of diabetes mellitus. The data collected during this study were done through a direct interview on the basis of an ethnobotanical survey form. The data of the study were analyzed on Excel and then SPSS version 22.0. Blood samples of 30 diabetic patients of both sexes subjected to plant-based treatments were collected. The different assays were performed at time 0 and 8 weeks after the first sample. The average age of the patients was 44.13 years with extremes of 18 and 70 years and a male predominance at 56%. Twenty-three medicinal plants were identified, 6 of which were used in the composition of three recipes for diabetic patients. The recipe composed of Leptadenia hastata + Guiera senegalensis had a 100% favorable effect on the carbohydrate parameters. On the other hand, the recipe composed of Boscia senegalensis+Anogeissus leiocarpus+Guiera senegalensis and the one composed of Prosopis africana+ Indigofera astragalana + Guiera senegalensis had a 57.1% and 55.6% favorable effect respectively on the carbohydrate parameters by restoring the glycemic balance All these 3 recipes had no toxic effect on the liver and kidneys: transaminases and creatine remained stable. A phytochemical and pharmacological study on animals with these plants will allow the development of phytomedicines against diabetes.},
 year = {2022}
}

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TY  - JOUR
T1  - Evaluation of Biological Parameters of Diabetic Patients Treated with Medicinal Plants: Case of the City of N'Djamena
AU  - Elise Dagosse
AU  - Memti Mberdoum Nguinambaye
AU  - Nadjioroum Ngam Asra
AU  - Brahim Boy Otchom
Y1  - 2022/11/10
PY  - 2022
N1  - https://doi.org/10.11648/j.jdmp.20220804.11
DO  - 10.11648/j.jdmp.20220804.11
T2  - Journal of Diseases and Medicinal Plants
JF  - Journal of Diseases and Medicinal Plants
JO  - Journal of Diseases and Medicinal Plants
SP  - 66
EP  - 73
PB  - Science Publishing Group
SN  - 2469-8210
UR  - https://doi.org/10.11648/j.jdmp.20220804.11
AB  - Diabetes is a metabolic disorder related to the secretion and / or absorption of insulin by the body, it is characterized mainly by a high level of glucose in the blood beyond 1.10 g / l. The objective of this study is to contribute to the development of medicinal plants that can help in the management of diabetes mellitus. The data collected during this study were done through a direct interview on the basis of an ethnobotanical survey form. The data of the study were analyzed on Excel and then SPSS version 22.0. Blood samples of 30 diabetic patients of both sexes subjected to plant-based treatments were collected. The different assays were performed at time 0 and 8 weeks after the first sample. The average age of the patients was 44.13 years with extremes of 18 and 70 years and a male predominance at 56%. Twenty-three medicinal plants were identified, 6 of which were used in the composition of three recipes for diabetic patients. The recipe composed of Leptadenia hastata + Guiera senegalensis had a 100% favorable effect on the carbohydrate parameters. On the other hand, the recipe composed of Boscia senegalensis+Anogeissus leiocarpus+Guiera senegalensis and the one composed of Prosopis africana+ Indigofera astragalana + Guiera senegalensis had a 57.1% and 55.6% favorable effect respectively on the carbohydrate parameters by restoring the glycemic balance All these 3 recipes had no toxic effect on the liver and kidneys: transaminases and creatine remained stable. A phytochemical and pharmacological study on animals with these plants will allow the development of phytomedicines against diabetes.
VL  - 8
IS  - 4
ER  -

Copy | Download