Observational Case Study on the Effectiveness of the Herbal Decoction Varanadi Kashaya in Managing Obesity of an Individual with Metabolic Disorders

Walpita Kankanamalage Anthoneen Ayesha Thilini Perera; Nambuhewage Dhammika Namal Jayawardhane

doi:doi:10.11648/j.jdmp.20230901.11

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Observational Case Study on the Effectiveness of the Herbal Decoction Varanadi Kashaya in Managing Obesity of an Individual with Metabolic Disorders

Walpita Kankanamalage Anthoneen Ayesha Thilini Perera, Nambuhewage Dhammika Namal Jayawardhane

Published in Journal of Diseases and Medicinal Plants (Volume 9, Issue 1)

Received: 24 June 2022 Accepted: 11 July 2022 Published: 9 January 2023

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Abstract

Obesity is increasing globally generating serious non-communicable diseases. The antiobesity drugs in the market don’t have any impact on adipocytes; the root cause of obesity, but give rise to many side effects. Several clinical studies have shown the potential of Varanadi Kashaya (VK) mentioned in Ayurveda classic Ashtanga Hrudaya in suppressing adipogenesis and lipid accumulation favoring anti-obesity action without any side effects. Yet, the efficacy of VK in managing obesity in individuals with metabolic disorders has not been evaluated in detail. As the constituents of VK has hypocholesterolemic, anti-diabetic and antioxidant characteristics it can address metabolic disorders as well. This study aims to determine the efficacy of VK in an obese individual with metabolic disorders. Materials and Methods: VK was given for 30 days to an obese person with diabetes and hyperlipidemia and evaluated the changes in anthropometry, Ayurveda parameters and laboratory investigations. Results: High-risk apple shape body shifted into a ratio between apple and pear threshold; a moderate risk to health problems by reducing weight/hip ratio (0.95 to 0.84), LDL (112.6 mg/dl to 106.2 mg/dl), total cholesterol (180 mg/dl to 171 mg/dl) and Non-HDL levels (132 mg/dl to 129 mg/dl) Conclusion: VK has the potency to address both subcutaneous and visceral fat; reducing obesity and controlling obesity-related metabolic disorders.

Published in	Journal of Diseases and Medicinal Plants (Volume 9, Issue 1)
DOI	10.11648/j.jdmp.20230901.11
Page(s)	1-6
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Ayurveda, Obesity, Pharmacological Attributes, Varanadi Kashaya

References

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[4]	Chinchu, J. U., & Mohan, M. C. (2020). Downregulation of adipogenic genes in 3T3-L1 Pre adipocytes-a possible mechanism of anti-obesity activity of herbal decoction Varanadi Kashayam. Journal of herbal medicine, 19, 100309.
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[14]	Chopade, V. V., Tankar, A. N., Pande, V. V., Tekade, A. R., Gowekar, N. M., Bhandari, S. R., & Khandake, S. N. (2008). Pongamia pinnata: Phytochemical constituents, traditional uses and pharmacological properties: A review. International Journal of Green Pharmacy (IJGP), 2 (2).
[15]	Bhuvad Sushama, B., & Nishteswar, K. (2013). Ayurvedic and Ethano botanical perspectives of chirabilva (Holoptelea Integrifolia Planch). Int Ayurvedic Med J, 1, 1-8.
[16]	Brilhante, R. S. N., Sales, J. A., Pereira, V. S., Castelo, D. D. S. C. M., de Aguiar Cordeiro, R., de Souza Sampaio, C. M., & Rocha, M. F. G. (2017). Research advances on the multiple uses of Moringa oleifera: A sustainable alternative for socially neglected population. Asian Pacific journal of tropical medicine, 10 (7), 621-630.
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Walpita Kankanamalage Anthoneen Ayesha Thilini Perera, Nambuhewage Dhammika Namal Jayawardhane. (2023). Observational Case Study on the Effectiveness of the Herbal Decoction Varanadi Kashaya in Managing Obesity of an Individual with Metabolic Disorders. Journal of Diseases and Medicinal Plants, 9(1), 1-6. https://doi.org/10.11648/j.jdmp.20230901.11

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ACS Style

Walpita Kankanamalage Anthoneen Ayesha Thilini Perera; Nambuhewage Dhammika Namal Jayawardhane. Observational Case Study on the Effectiveness of the Herbal Decoction Varanadi Kashaya in Managing Obesity of an Individual with Metabolic Disorders. J. Dis. Med. Plants 2023, 9(1), 1-6. doi: 10.11648/j.jdmp.20230901.11

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AMA Style

Walpita Kankanamalage Anthoneen Ayesha Thilini Perera, Nambuhewage Dhammika Namal Jayawardhane. Observational Case Study on the Effectiveness of the Herbal Decoction Varanadi Kashaya in Managing Obesity of an Individual with Metabolic Disorders. J Dis Med Plants. 2023;9(1):1-6. doi: 10.11648/j.jdmp.20230901.11

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@article{10.11648/j.jdmp.20230901.11,
  author = {Walpita Kankanamalage Anthoneen Ayesha Thilini Perera and Nambuhewage Dhammika Namal Jayawardhane},
  title = {Observational Case Study on the Effectiveness of the Herbal Decoction Varanadi Kashaya in Managing Obesity of an Individual with Metabolic Disorders},
  journal = {Journal of Diseases and Medicinal Plants},
  volume = {9},
  number = {1},
  pages = {1-6},
  doi = {10.11648/j.jdmp.20230901.11},
  url = {https://doi.org/10.11648/j.jdmp.20230901.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jdmp.20230901.11},
  abstract = {Obesity is increasing globally generating serious non-communicable diseases. The antiobesity drugs in the market don’t have any impact on adipocytes; the root cause of obesity, but give rise to many side effects. Several clinical studies have shown the potential of Varanadi Kashaya (VK) mentioned in Ayurveda classic Ashtanga Hrudaya in suppressing adipogenesis and lipid accumulation favoring anti-obesity action without any side effects. Yet, the efficacy of VK in managing obesity in individuals with metabolic disorders has not been evaluated in detail. As the constituents of VK has hypocholesterolemic, anti-diabetic and antioxidant characteristics it can address metabolic disorders as well. This study aims to determine the efficacy of VK in an obese individual with metabolic disorders. Materials and Methods: VK was given for 30 days to an obese person with diabetes and hyperlipidemia and evaluated the changes in anthropometry, Ayurveda parameters and laboratory investigations. Results: High-risk apple shape body shifted into a ratio between apple and pear threshold; a moderate risk to health problems by reducing weight/hip ratio (0.95 to 0.84), LDL (112.6 mg/dl to 106.2 mg/dl), total cholesterol (180 mg/dl to 171 mg/dl) and Non-HDL levels (132 mg/dl to 129 mg/dl) Conclusion: VK has the potency to address both subcutaneous and visceral fat; reducing obesity and controlling obesity-related metabolic disorders.},
 year = {2023}
}

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TY  - JOUR
T1  - Observational Case Study on the Effectiveness of the Herbal Decoction Varanadi Kashaya in Managing Obesity of an Individual with Metabolic Disorders
AU  - Walpita Kankanamalage Anthoneen Ayesha Thilini Perera
AU  - Nambuhewage Dhammika Namal Jayawardhane
Y1  - 2023/01/09
PY  - 2023
N1  - https://doi.org/10.11648/j.jdmp.20230901.11
DO  - 10.11648/j.jdmp.20230901.11
T2  - Journal of Diseases and Medicinal Plants
JF  - Journal of Diseases and Medicinal Plants
JO  - Journal of Diseases and Medicinal Plants
SP  - 1
EP  - 6
PB  - Science Publishing Group
SN  - 2469-8210
UR  - https://doi.org/10.11648/j.jdmp.20230901.11
AB  - Obesity is increasing globally generating serious non-communicable diseases. The antiobesity drugs in the market don’t have any impact on adipocytes; the root cause of obesity, but give rise to many side effects. Several clinical studies have shown the potential of Varanadi Kashaya (VK) mentioned in Ayurveda classic Ashtanga Hrudaya in suppressing adipogenesis and lipid accumulation favoring anti-obesity action without any side effects. Yet, the efficacy of VK in managing obesity in individuals with metabolic disorders has not been evaluated in detail. As the constituents of VK has hypocholesterolemic, anti-diabetic and antioxidant characteristics it can address metabolic disorders as well. This study aims to determine the efficacy of VK in an obese individual with metabolic disorders. Materials and Methods: VK was given for 30 days to an obese person with diabetes and hyperlipidemia and evaluated the changes in anthropometry, Ayurveda parameters and laboratory investigations. Results: High-risk apple shape body shifted into a ratio between apple and pear threshold; a moderate risk to health problems by reducing weight/hip ratio (0.95 to 0.84), LDL (112.6 mg/dl to 106.2 mg/dl), total cholesterol (180 mg/dl to 171 mg/dl) and Non-HDL levels (132 mg/dl to 129 mg/dl) Conclusion: VK has the potency to address both subcutaneous and visceral fat; reducing obesity and controlling obesity-related metabolic disorders.
VL  - 9
IS  - 1
ER  -

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Author Information

Walpita Kankanamalage Anthoneen Ayesha Thilini Perera

Institute of Indigenous Medicine, University of Colombo, Rajagiriya, Sri Lanka
Nambuhewage Dhammika Namal Jayawardhane

Institute of Indigenous Medicine, University of Colombo, Rajagiriya, Sri Lanka

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APA Style

Walpita Kankanamalage Anthoneen Ayesha Thilini Perera, Nambuhewage Dhammika Namal Jayawardhane. (2023). Observational Case Study on the Effectiveness of the Herbal Decoction Varanadi Kashaya in Managing Obesity of an Individual with Metabolic Disorders. Journal of Diseases and Medicinal Plants, 9(1), 1-6. https://doi.org/10.11648/j.jdmp.20230901.11

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ACS Style

Walpita Kankanamalage Anthoneen Ayesha Thilini Perera; Nambuhewage Dhammika Namal Jayawardhane. Observational Case Study on the Effectiveness of the Herbal Decoction Varanadi Kashaya in Managing Obesity of an Individual with Metabolic Disorders. J. Dis. Med. Plants 2023, 9(1), 1-6. doi: 10.11648/j.jdmp.20230901.11

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AMA Style

Walpita Kankanamalage Anthoneen Ayesha Thilini Perera, Nambuhewage Dhammika Namal Jayawardhane. Observational Case Study on the Effectiveness of the Herbal Decoction Varanadi Kashaya in Managing Obesity of an Individual with Metabolic Disorders. J Dis Med Plants. 2023;9(1):1-6. doi: 10.11648/j.jdmp.20230901.11

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@article{10.11648/j.jdmp.20230901.11,
  author = {Walpita Kankanamalage Anthoneen Ayesha Thilini Perera and Nambuhewage Dhammika Namal Jayawardhane},
  title = {Observational Case Study on the Effectiveness of the Herbal Decoction Varanadi Kashaya in Managing Obesity of an Individual with Metabolic Disorders},
  journal = {Journal of Diseases and Medicinal Plants},
  volume = {9},
  number = {1},
  pages = {1-6},
  doi = {10.11648/j.jdmp.20230901.11},
  url = {https://doi.org/10.11648/j.jdmp.20230901.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jdmp.20230901.11},
  abstract = {Obesity is increasing globally generating serious non-communicable diseases. The antiobesity drugs in the market don’t have any impact on adipocytes; the root cause of obesity, but give rise to many side effects. Several clinical studies have shown the potential of Varanadi Kashaya (VK) mentioned in Ayurveda classic Ashtanga Hrudaya in suppressing adipogenesis and lipid accumulation favoring anti-obesity action without any side effects. Yet, the efficacy of VK in managing obesity in individuals with metabolic disorders has not been evaluated in detail. As the constituents of VK has hypocholesterolemic, anti-diabetic and antioxidant characteristics it can address metabolic disorders as well. This study aims to determine the efficacy of VK in an obese individual with metabolic disorders. Materials and Methods: VK was given for 30 days to an obese person with diabetes and hyperlipidemia and evaluated the changes in anthropometry, Ayurveda parameters and laboratory investigations. Results: High-risk apple shape body shifted into a ratio between apple and pear threshold; a moderate risk to health problems by reducing weight/hip ratio (0.95 to 0.84), LDL (112.6 mg/dl to 106.2 mg/dl), total cholesterol (180 mg/dl to 171 mg/dl) and Non-HDL levels (132 mg/dl to 129 mg/dl) Conclusion: VK has the potency to address both subcutaneous and visceral fat; reducing obesity and controlling obesity-related metabolic disorders.},
 year = {2023}
}

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TY  - JOUR
T1  - Observational Case Study on the Effectiveness of the Herbal Decoction Varanadi Kashaya in Managing Obesity of an Individual with Metabolic Disorders
AU  - Walpita Kankanamalage Anthoneen Ayesha Thilini Perera
AU  - Nambuhewage Dhammika Namal Jayawardhane
Y1  - 2023/01/09
PY  - 2023
N1  - https://doi.org/10.11648/j.jdmp.20230901.11
DO  - 10.11648/j.jdmp.20230901.11
T2  - Journal of Diseases and Medicinal Plants
JF  - Journal of Diseases and Medicinal Plants
JO  - Journal of Diseases and Medicinal Plants
SP  - 1
EP  - 6
PB  - Science Publishing Group
SN  - 2469-8210
UR  - https://doi.org/10.11648/j.jdmp.20230901.11
AB  - Obesity is increasing globally generating serious non-communicable diseases. The antiobesity drugs in the market don’t have any impact on adipocytes; the root cause of obesity, but give rise to many side effects. Several clinical studies have shown the potential of Varanadi Kashaya (VK) mentioned in Ayurveda classic Ashtanga Hrudaya in suppressing adipogenesis and lipid accumulation favoring anti-obesity action without any side effects. Yet, the efficacy of VK in managing obesity in individuals with metabolic disorders has not been evaluated in detail. As the constituents of VK has hypocholesterolemic, anti-diabetic and antioxidant characteristics it can address metabolic disorders as well. This study aims to determine the efficacy of VK in an obese individual with metabolic disorders. Materials and Methods: VK was given for 30 days to an obese person with diabetes and hyperlipidemia and evaluated the changes in anthropometry, Ayurveda parameters and laboratory investigations. Results: High-risk apple shape body shifted into a ratio between apple and pear threshold; a moderate risk to health problems by reducing weight/hip ratio (0.95 to 0.84), LDL (112.6 mg/dl to 106.2 mg/dl), total cholesterol (180 mg/dl to 171 mg/dl) and Non-HDL levels (132 mg/dl to 129 mg/dl) Conclusion: VK has the potency to address both subcutaneous and visceral fat; reducing obesity and controlling obesity-related metabolic disorders.
VL  - 9
IS  - 1
ER  -

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