A Case of Very Severe Anemia in Pregnancy Combined with Beta-Thalassemia Major and Pre-Eclampsia

Xuan Gong; Xiaomin Xiao

doi:doi:10.11648/j.jgo.20231102.12

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A Case of Very Severe Anemia in Pregnancy Combined with Beta-Thalassemia Major and Pre-Eclampsia

Xuan Gong, Xiaomin Xiao

Published in Journal of Gynecology and Obstetrics (Volume 11, Issue 2)

Received: 5 March 2023 Accepted: 30 March 2023 Published: 11 April 2023

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Abstract

OBJECTIVE: To investigate the clinical diagnosis, preventive antenatal screening and antenatal diagnosis, pregnancy management, timing and mode of delivery and postnatal management of β-thalassaemia in pregnancy combined. METHODS: Retrospective analysis of the medical history and treatment of a patient with β-thalassaemia in pregnancy combined with pregnancy outcome. RESULTS: The patient recovered well, had a normal temperature, the abdominal incision was removed at 7 d, the II/nail healed, the general obstetric condition was acceptable and she was discharged successfully. CONCLUSION: Anaemia is very common in pregnancy, but very severe anaemia in pregnancy is extremely rare and it is important to define the cause of anaemia. Thalassaemia is a group of inherited chronic haemolytic disorders caused by autosomal defects, which can be aggravated by pregnancy. Thalassaemia can be divided into α-, β-, γ-, δ-, δβ- and other categories, and for β-thalassaemia it can be divided into mild, moderate and severe, with both intermediate and severe patients presenting early with obvious anaemic symptoms and relying on long-term transfusion therapy. The majority of these patients die in childhood and are extremely rare in pregnancy. Thalassaemia in pregnancy can directly affect the outcome of pregnancy and cause many near and long-term complications in the newborn, and timely antenatal screening and prenatal diagnosis can detect the disease early. Active obstetric management and timing of pregnancy can also help to improve maternal and infant pregnancy outcomes.

Published in	Journal of Gynecology and Obstetrics (Volume 11, Issue 2)
DOI	10.11648/j.jgo.20231102.12
Page(s)	36-40
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Pregnancy, Beta-Thalassemia, Very Severe Anaemia, Pre-eclampsia

References

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APA Style

Xuan Gong, Xiaomin Xiao. (2023). A Case of Very Severe Anemia in Pregnancy Combined with Beta-Thalassemia Major and Pre-Eclampsia. Journal of Gynecology and Obstetrics, 11(2), 36-40. https://doi.org/10.11648/j.jgo.20231102.12

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ACS Style

Xuan Gong; Xiaomin Xiao. A Case of Very Severe Anemia in Pregnancy Combined with Beta-Thalassemia Major and Pre-Eclampsia. J. Gynecol. Obstet. 2023, 11(2), 36-40. doi: 10.11648/j.jgo.20231102.12

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AMA Style

Xuan Gong, Xiaomin Xiao. A Case of Very Severe Anemia in Pregnancy Combined with Beta-Thalassemia Major and Pre-Eclampsia. J Gynecol Obstet. 2023;11(2):36-40. doi: 10.11648/j.jgo.20231102.12

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@article{10.11648/j.jgo.20231102.12,
  author = {Xuan Gong and Xiaomin Xiao},
  title = {A Case of Very Severe Anemia in Pregnancy Combined with Beta-Thalassemia Major and Pre-Eclampsia},
  journal = {Journal of Gynecology and Obstetrics},
  volume = {11},
  number = {2},
  pages = {36-40},
  doi = {10.11648/j.jgo.20231102.12},
  url = {https://doi.org/10.11648/j.jgo.20231102.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jgo.20231102.12},
  abstract = {OBJECTIVE: To investigate the clinical diagnosis, preventive antenatal screening and antenatal diagnosis, pregnancy management, timing and mode of delivery and postnatal management of β-thalassaemia in pregnancy combined. METHODS: Retrospective analysis of the medical history and treatment of a patient with β-thalassaemia in pregnancy combined with pregnancy outcome. RESULTS: The patient recovered well, had a normal temperature, the abdominal incision was removed at 7 d, the II/nail healed, the general obstetric condition was acceptable and she was discharged successfully. CONCLUSION: Anaemia is very common in pregnancy, but very severe anaemia in pregnancy is extremely rare and it is important to define the cause of anaemia. Thalassaemia is a group of inherited chronic haemolytic disorders caused by autosomal defects, which can be aggravated by pregnancy. Thalassaemia can be divided into α-, β-, γ-, δ-, δβ- and other categories, and for β-thalassaemia it can be divided into mild, moderate and severe, with both intermediate and severe patients presenting early with obvious anaemic symptoms and relying on long-term transfusion therapy. The majority of these patients die in childhood and are extremely rare in pregnancy. Thalassaemia in pregnancy can directly affect the outcome of pregnancy and cause many near and long-term complications in the newborn, and timely antenatal screening and prenatal diagnosis can detect the disease early. Active obstetric management and timing of pregnancy can also help to improve maternal and infant pregnancy outcomes.},
 year = {2023}
}

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TY  - JOUR
T1  - A Case of Very Severe Anemia in Pregnancy Combined with Beta-Thalassemia Major and Pre-Eclampsia
AU  - Xuan Gong
AU  - Xiaomin Xiao
Y1  - 2023/04/11
PY  - 2023
N1  - https://doi.org/10.11648/j.jgo.20231102.12
DO  - 10.11648/j.jgo.20231102.12
T2  - Journal of Gynecology and Obstetrics
JF  - Journal of Gynecology and Obstetrics
JO  - Journal of Gynecology and Obstetrics
SP  - 36
EP  - 40
PB  - Science Publishing Group
SN  - 2376-7820
UR  - https://doi.org/10.11648/j.jgo.20231102.12
AB  - OBJECTIVE: To investigate the clinical diagnosis, preventive antenatal screening and antenatal diagnosis, pregnancy management, timing and mode of delivery and postnatal management of β-thalassaemia in pregnancy combined. METHODS: Retrospective analysis of the medical history and treatment of a patient with β-thalassaemia in pregnancy combined with pregnancy outcome. RESULTS: The patient recovered well, had a normal temperature, the abdominal incision was removed at 7 d, the II/nail healed, the general obstetric condition was acceptable and she was discharged successfully. CONCLUSION: Anaemia is very common in pregnancy, but very severe anaemia in pregnancy is extremely rare and it is important to define the cause of anaemia. Thalassaemia is a group of inherited chronic haemolytic disorders caused by autosomal defects, which can be aggravated by pregnancy. Thalassaemia can be divided into α-, β-, γ-, δ-, δβ- and other categories, and for β-thalassaemia it can be divided into mild, moderate and severe, with both intermediate and severe patients presenting early with obvious anaemic symptoms and relying on long-term transfusion therapy. The majority of these patients die in childhood and are extremely rare in pregnancy. Thalassaemia in pregnancy can directly affect the outcome of pregnancy and cause many near and long-term complications in the newborn, and timely antenatal screening and prenatal diagnosis can detect the disease early. Active obstetric management and timing of pregnancy can also help to improve maternal and infant pregnancy outcomes.
VL  - 11
IS  - 2
ER  -

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Author Information

Xuan Gong

First School of Clinical Medicine, Jinan University, Guangzhou, China
Xiaomin Xiao

First School of Clinical Medicine, Jinan University, Guangzhou, China

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APA Style

Xuan Gong, Xiaomin Xiao. (2023). A Case of Very Severe Anemia in Pregnancy Combined with Beta-Thalassemia Major and Pre-Eclampsia. Journal of Gynecology and Obstetrics, 11(2), 36-40. https://doi.org/10.11648/j.jgo.20231102.12

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ACS Style

Xuan Gong; Xiaomin Xiao. A Case of Very Severe Anemia in Pregnancy Combined with Beta-Thalassemia Major and Pre-Eclampsia. J. Gynecol. Obstet. 2023, 11(2), 36-40. doi: 10.11648/j.jgo.20231102.12

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AMA Style

Xuan Gong, Xiaomin Xiao. A Case of Very Severe Anemia in Pregnancy Combined with Beta-Thalassemia Major and Pre-Eclampsia. J Gynecol Obstet. 2023;11(2):36-40. doi: 10.11648/j.jgo.20231102.12

Copy | Download

@article{10.11648/j.jgo.20231102.12,
  author = {Xuan Gong and Xiaomin Xiao},
  title = {A Case of Very Severe Anemia in Pregnancy Combined with Beta-Thalassemia Major and Pre-Eclampsia},
  journal = {Journal of Gynecology and Obstetrics},
  volume = {11},
  number = {2},
  pages = {36-40},
  doi = {10.11648/j.jgo.20231102.12},
  url = {https://doi.org/10.11648/j.jgo.20231102.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jgo.20231102.12},
  abstract = {OBJECTIVE: To investigate the clinical diagnosis, preventive antenatal screening and antenatal diagnosis, pregnancy management, timing and mode of delivery and postnatal management of β-thalassaemia in pregnancy combined. METHODS: Retrospective analysis of the medical history and treatment of a patient with β-thalassaemia in pregnancy combined with pregnancy outcome. RESULTS: The patient recovered well, had a normal temperature, the abdominal incision was removed at 7 d, the II/nail healed, the general obstetric condition was acceptable and she was discharged successfully. CONCLUSION: Anaemia is very common in pregnancy, but very severe anaemia in pregnancy is extremely rare and it is important to define the cause of anaemia. Thalassaemia is a group of inherited chronic haemolytic disorders caused by autosomal defects, which can be aggravated by pregnancy. Thalassaemia can be divided into α-, β-, γ-, δ-, δβ- and other categories, and for β-thalassaemia it can be divided into mild, moderate and severe, with both intermediate and severe patients presenting early with obvious anaemic symptoms and relying on long-term transfusion therapy. The majority of these patients die in childhood and are extremely rare in pregnancy. Thalassaemia in pregnancy can directly affect the outcome of pregnancy and cause many near and long-term complications in the newborn, and timely antenatal screening and prenatal diagnosis can detect the disease early. Active obstetric management and timing of pregnancy can also help to improve maternal and infant pregnancy outcomes.},
 year = {2023}
}

Copy | Download

TY  - JOUR
T1  - A Case of Very Severe Anemia in Pregnancy Combined with Beta-Thalassemia Major and Pre-Eclampsia
AU  - Xuan Gong
AU  - Xiaomin Xiao
Y1  - 2023/04/11
PY  - 2023
N1  - https://doi.org/10.11648/j.jgo.20231102.12
DO  - 10.11648/j.jgo.20231102.12
T2  - Journal of Gynecology and Obstetrics
JF  - Journal of Gynecology and Obstetrics
JO  - Journal of Gynecology and Obstetrics
SP  - 36
EP  - 40
PB  - Science Publishing Group
SN  - 2376-7820
UR  - https://doi.org/10.11648/j.jgo.20231102.12
AB  - OBJECTIVE: To investigate the clinical diagnosis, preventive antenatal screening and antenatal diagnosis, pregnancy management, timing and mode of delivery and postnatal management of β-thalassaemia in pregnancy combined. METHODS: Retrospective analysis of the medical history and treatment of a patient with β-thalassaemia in pregnancy combined with pregnancy outcome. RESULTS: The patient recovered well, had a normal temperature, the abdominal incision was removed at 7 d, the II/nail healed, the general obstetric condition was acceptable and she was discharged successfully. CONCLUSION: Anaemia is very common in pregnancy, but very severe anaemia in pregnancy is extremely rare and it is important to define the cause of anaemia. Thalassaemia is a group of inherited chronic haemolytic disorders caused by autosomal defects, which can be aggravated by pregnancy. Thalassaemia can be divided into α-, β-, γ-, δ-, δβ- and other categories, and for β-thalassaemia it can be divided into mild, moderate and severe, with both intermediate and severe patients presenting early with obvious anaemic symptoms and relying on long-term transfusion therapy. The majority of these patients die in childhood and are extremely rare in pregnancy. Thalassaemia in pregnancy can directly affect the outcome of pregnancy and cause many near and long-term complications in the newborn, and timely antenatal screening and prenatal diagnosis can detect the disease early. Active obstetric management and timing of pregnancy can also help to improve maternal and infant pregnancy outcomes.
VL  - 11
IS  - 2
ER  -

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