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Mature Cystic Teratoma in the Head of the Pancreas: An Unexpected Finding

Received: 13 August 2021    Accepted: 24 August 2021    Published: 31 August 2021
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Abstract

Background: Teratomas are tumors that arise from germ cells in mature gonads and along the midline as extragonadal teratomas. The latter are infrequent, with few cases having been described in the pancreas. Objective: Our aim is to emphasize the importance of determining the histological features of extragonadal teratomas. Case presentation: We present the case of a mature cystic teratoma in the pancreas with focal neuroendocrine differentiation identified in a thirty-five year old male patient with no apparent symptomatology of a pancreatic tumor. The tumor was an unexpected finding made upon a diagnostic approach for SARS-CoV-2 infection. Discussion: At present, there are around fifty reported cases of teratomas in the pancreas. The majority of these are dermoid cysts. Few are mature cystic teratomas, and there is one reported case of an immature teratoma. Of the mature cystic teratomas reported in the literature, one presented a somatic neoplasm. Conclusion: The case highlights the importance on determining the histological features of extragonadal teratomas, including each type of tissue, the degree of differentiation and the presence of benign or malignant neoplasms, as these elements are key to classify teratomas appropriately.

Published in World Journal of Medical Case Reports (Volume 2, Issue 3)
DOI 10.11648/j.wjmcr.20210203.16
Page(s) 55-61
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Germ Cell Tumors, Extragonadal Teratoma, Mature Teratoma, Pancreas, Pathology

References
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    Juan Jose Andrade-Rojas, María José Lizardo-Thiebaud, Guillermo Andrade-Orozco, Leonel Contreras-Loera, Nelsy Liseth Garza-Hinojosa, et al. (2021). Mature Cystic Teratoma in the Head of the Pancreas: An Unexpected Finding. World Journal of Medical Case Reports, 2(3), 55-61. https://doi.org/10.11648/j.wjmcr.20210203.16

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    ACS Style

    Juan Jose Andrade-Rojas; María José Lizardo-Thiebaud; Guillermo Andrade-Orozco; Leonel Contreras-Loera; Nelsy Liseth Garza-Hinojosa, et al. Mature Cystic Teratoma in the Head of the Pancreas: An Unexpected Finding. World J. Med. Case Rep. 2021, 2(3), 55-61. doi: 10.11648/j.wjmcr.20210203.16

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    AMA Style

    Juan Jose Andrade-Rojas, María José Lizardo-Thiebaud, Guillermo Andrade-Orozco, Leonel Contreras-Loera, Nelsy Liseth Garza-Hinojosa, et al. Mature Cystic Teratoma in the Head of the Pancreas: An Unexpected Finding. World J Med Case Rep. 2021;2(3):55-61. doi: 10.11648/j.wjmcr.20210203.16

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  • @article{10.11648/j.wjmcr.20210203.16,
      author = {Juan Jose Andrade-Rojas and María José Lizardo-Thiebaud and Guillermo Andrade-Orozco and Leonel Contreras-Loera and Nelsy Liseth Garza-Hinojosa and Maria Guadalupe Jazmín De Anda-Gonzalez},
      title = {Mature Cystic Teratoma in the Head of the Pancreas: An Unexpected Finding},
      journal = {World Journal of Medical Case Reports},
      volume = {2},
      number = {3},
      pages = {55-61},
      doi = {10.11648/j.wjmcr.20210203.16},
      url = {https://doi.org/10.11648/j.wjmcr.20210203.16},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.wjmcr.20210203.16},
      abstract = {Background: Teratomas are tumors that arise from germ cells in mature gonads and along the midline as extragonadal teratomas. The latter are infrequent, with few cases having been described in the pancreas. Objective: Our aim is to emphasize the importance of determining the histological features of extragonadal teratomas. Case presentation: We present the case of a mature cystic teratoma in the pancreas with focal neuroendocrine differentiation identified in a thirty-five year old male patient with no apparent symptomatology of a pancreatic tumor. The tumor was an unexpected finding made upon a diagnostic approach for SARS-CoV-2 infection. Discussion: At present, there are around fifty reported cases of teratomas in the pancreas. The majority of these are dermoid cysts. Few are mature cystic teratomas, and there is one reported case of an immature teratoma. Of the mature cystic teratomas reported in the literature, one presented a somatic neoplasm. Conclusion: The case highlights the importance on determining the histological features of extragonadal teratomas, including each type of tissue, the degree of differentiation and the presence of benign or malignant neoplasms, as these elements are key to classify teratomas appropriately.},
     year = {2021}
    }
    

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  • TY  - JOUR
    T1  - Mature Cystic Teratoma in the Head of the Pancreas: An Unexpected Finding
    AU  - Juan Jose Andrade-Rojas
    AU  - María José Lizardo-Thiebaud
    AU  - Guillermo Andrade-Orozco
    AU  - Leonel Contreras-Loera
    AU  - Nelsy Liseth Garza-Hinojosa
    AU  - Maria Guadalupe Jazmín De Anda-Gonzalez
    Y1  - 2021/08/31
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    DO  - 10.11648/j.wjmcr.20210203.16
    T2  - World Journal of Medical Case Reports
    JF  - World Journal of Medical Case Reports
    JO  - World Journal of Medical Case Reports
    SP  - 55
    EP  - 61
    PB  - Science Publishing Group
    SN  - 2994-726X
    UR  - https://doi.org/10.11648/j.wjmcr.20210203.16
    AB  - Background: Teratomas are tumors that arise from germ cells in mature gonads and along the midline as extragonadal teratomas. The latter are infrequent, with few cases having been described in the pancreas. Objective: Our aim is to emphasize the importance of determining the histological features of extragonadal teratomas. Case presentation: We present the case of a mature cystic teratoma in the pancreas with focal neuroendocrine differentiation identified in a thirty-five year old male patient with no apparent symptomatology of a pancreatic tumor. The tumor was an unexpected finding made upon a diagnostic approach for SARS-CoV-2 infection. Discussion: At present, there are around fifty reported cases of teratomas in the pancreas. The majority of these are dermoid cysts. Few are mature cystic teratomas, and there is one reported case of an immature teratoma. Of the mature cystic teratomas reported in the literature, one presented a somatic neoplasm. Conclusion: The case highlights the importance on determining the histological features of extragonadal teratomas, including each type of tissue, the degree of differentiation and the presence of benign or malignant neoplasms, as these elements are key to classify teratomas appropriately.
    VL  - 2
    IS  - 3
    ER  - 

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Author Information
  • Department of Anatomic Pathology, Instituto Nacional de Ciencias Médicas y Nutricion Salvador Zubirán, Mexico City, Mexico

  • Department of Anatomic Pathology, Instituto Nacional de Ciencias Médicas y Nutricion Salvador Zubirán, Mexico City, Mexico

  • Department of Anatomic Pathology, Instituto Nacional de Ciencias Médicas y Nutricion Salvador Zubirán, Mexico City, Mexico

  • Department of Anatomic Pathology, Hospital Central Doctor Ignacio Morones Prieto, San Luis Potosi, Mexico

  • Department of Dermatology, Centro Medico Nacional del Noroeste UMAE25, Nuevo Leon, Mexico

  • Department of Anatomic Pathology, Instituto Nacional de Ciencias Médicas y Nutricion Salvador Zubirán, Mexico City, Mexico

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