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Factors Associated with Mortality in COVID-19 Patients with Comorbidities Who Were Hospitalized in the Different CT-EPI in the Labe Region, Guinea 2020-2022

Received: 20 March 2023    Accepted: 13 April 2023    Published: 25 May 2023
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Abstract

Coronavirus infectious disease (COVID-19) shows remarkable symptomatic heterogeneity. To date, only a few demographic and clinical factors, such as advanced age, diabetes, and cardiovascular disease, have been associated with poor outcomes and increased risk of mortality from COVID-19. In the Labe region, the lethality of COVID-19 disease remains high in people with comorbidities. In our study, comorbidities were frequently associated with COVID-19 infection and were dominated by hypertension and diabetes. This recognition may help direct efforts toward prevention and management. The objective of the study was to describe the factors associated with mortality in COVID-19 patients with comorbidities hospitalized in the Labe region (Epidemiological Treatment Centers -CT Epi- and home). Methods: The study was carried out in the CT-Epi of COVID-19. It focused on the analysis of 1443 records of patients hospitalized in the CT-Epi of the Labe Region. It was a transversal and analytical study conducted in July 2022. Factors associated with mortality in patients with comorbidities were identified through patient records and content analysis. Results: A total of 1443 patients with COVID-19 hospitalized in the Labe region participated in our study, including 244 with comorbidities and 1199 patients with COVID-19 without comorbidities. Among these patients in our study, 823 were men and 620 were women, i.e., a M/F sex ratio of 1.33. The average age was 45 years (Min= 7 years; Max= 99 years). Bivariate analysis showed that there was a statistically significant association between comorbidities and the occurrence of death in patients with COVID-19. There is a positive association between this risk factor, which is comorbidity, and the occurrence of death. Therefore, we say that comorbidities are risk factors that are responsible for the occurrence of death in patients with COVID-19 in the Labe region. Conclusion: In our study, advanced age, hypertension, diabetes, HIV, and chronic lung disease were the main risk factors for hospitalization or death due to COVID-19 in the Labe region. Further research is needed to identify risk factors associated with severe forms and mortality of COVID-19 to optimize management of patients with comorbidities. This study places particular emphasis on the priority targets (people over 60 and people with co-morbidities) of accelerated vaccination campaigns against COVID-19.

Published in World Journal of Public Health (Volume 8, Issue 2)
DOI 10.11648/j.wjph.20230802.25
Page(s) 139-147
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Mortality, Comorbidities, Associated Factors, COVID-19, CT-EPI of Labe, Guinea

References
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Cite This Article
  • APA Style

    Jean Konan Kouame, Sadou Sow, Abdoulaye Sow, Alpha Oumar Diallo, Mamadou Oury Balde, et al. (2023). Factors Associated with Mortality in COVID-19 Patients with Comorbidities Who Were Hospitalized in the Different CT-EPI in the Labe Region, Guinea 2020-2022. World Journal of Public Health, 8(2), 139-147. https://doi.org/10.11648/j.wjph.20230802.25

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    ACS Style

    Jean Konan Kouame; Sadou Sow; Abdoulaye Sow; Alpha Oumar Diallo; Mamadou Oury Balde, et al. Factors Associated with Mortality in COVID-19 Patients with Comorbidities Who Were Hospitalized in the Different CT-EPI in the Labe Region, Guinea 2020-2022. World J. Public Health 2023, 8(2), 139-147. doi: 10.11648/j.wjph.20230802.25

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    AMA Style

    Jean Konan Kouame, Sadou Sow, Abdoulaye Sow, Alpha Oumar Diallo, Mamadou Oury Balde, et al. Factors Associated with Mortality in COVID-19 Patients with Comorbidities Who Were Hospitalized in the Different CT-EPI in the Labe Region, Guinea 2020-2022. World J Public Health. 2023;8(2):139-147. doi: 10.11648/j.wjph.20230802.25

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  • @article{10.11648/j.wjph.20230802.25,
      author = {Jean Konan Kouame and Sadou Sow and Abdoulaye Sow and Alpha Oumar Diallo and Mamadou Oury Balde and Kevin Yohou Sylvestre and Seydou Dia and Mariama Souaré and Mamadou Alpha Diallo and Kadiata Bah and Alain Ntumba Katende and Mouctar Kande and Sekou Solano and Kassié Fangamou and Amadou Lamarana Sow and Mamadou Pathe Bah and N'Famara Bangoura and Abdoulaye Barry and Zeze Beavogui and Mangue Sylla and Sekou Sylla and Issiaga Konate and Fode Bangaly Duakite and Mohamed Sankhon and Dadja Essoya Lando and Amadou Bailo Diallo and Jean Marie Kipela},
      title = {Factors Associated with Mortality in COVID-19 Patients with Comorbidities Who Were Hospitalized in the Different CT-EPI in the Labe Region, Guinea 2020-2022},
      journal = {World Journal of Public Health},
      volume = {8},
      number = {2},
      pages = {139-147},
      doi = {10.11648/j.wjph.20230802.25},
      url = {https://doi.org/10.11648/j.wjph.20230802.25},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.wjph.20230802.25},
      abstract = {Coronavirus infectious disease (COVID-19) shows remarkable symptomatic heterogeneity. To date, only a few demographic and clinical factors, such as advanced age, diabetes, and cardiovascular disease, have been associated with poor outcomes and increased risk of mortality from COVID-19. In the Labe region, the lethality of COVID-19 disease remains high in people with comorbidities. In our study, comorbidities were frequently associated with COVID-19 infection and were dominated by hypertension and diabetes. This recognition may help direct efforts toward prevention and management. The objective of the study was to describe the factors associated with mortality in COVID-19 patients with comorbidities hospitalized in the Labe region (Epidemiological Treatment Centers -CT Epi- and home). Methods: The study was carried out in the CT-Epi of COVID-19. It focused on the analysis of 1443 records of patients hospitalized in the CT-Epi of the Labe Region. It was a transversal and analytical study conducted in July 2022. Factors associated with mortality in patients with comorbidities were identified through patient records and content analysis. Results: A total of 1443 patients with COVID-19 hospitalized in the Labe region participated in our study, including 244 with comorbidities and 1199 patients with COVID-19 without comorbidities. Among these patients in our study, 823 were men and 620 were women, i.e., a M/F sex ratio of 1.33. The average age was 45 years (Min= 7 years; Max= 99 years). Bivariate analysis showed that there was a statistically significant association between comorbidities and the occurrence of death in patients with COVID-19. There is a positive association between this risk factor, which is comorbidity, and the occurrence of death. Therefore, we say that comorbidities are risk factors that are responsible for the occurrence of death in patients with COVID-19 in the Labe region. Conclusion: In our study, advanced age, hypertension, diabetes, HIV, and chronic lung disease were the main risk factors for hospitalization or death due to COVID-19 in the Labe region. Further research is needed to identify risk factors associated with severe forms and mortality of COVID-19 to optimize management of patients with comorbidities. This study places particular emphasis on the priority targets (people over 60 and people with co-morbidities) of accelerated vaccination campaigns against COVID-19.},
     year = {2023}
    }
    

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  • TY  - JOUR
    T1  - Factors Associated with Mortality in COVID-19 Patients with Comorbidities Who Were Hospitalized in the Different CT-EPI in the Labe Region, Guinea 2020-2022
    AU  - Jean Konan Kouame
    AU  - Sadou Sow
    AU  - Abdoulaye Sow
    AU  - Alpha Oumar Diallo
    AU  - Mamadou Oury Balde
    AU  - Kevin Yohou Sylvestre
    AU  - Seydou Dia
    AU  - Mariama Souaré
    AU  - Mamadou Alpha Diallo
    AU  - Kadiata Bah
    AU  - Alain Ntumba Katende
    AU  - Mouctar Kande
    AU  - Sekou Solano
    AU  - Kassié Fangamou
    AU  - Amadou Lamarana Sow
    AU  - Mamadou Pathe Bah
    AU  - N'Famara Bangoura
    AU  - Abdoulaye Barry
    AU  - Zeze Beavogui
    AU  - Mangue Sylla
    AU  - Sekou Sylla
    AU  - Issiaga Konate
    AU  - Fode Bangaly Duakite
    AU  - Mohamed Sankhon
    AU  - Dadja Essoya Lando
    AU  - Amadou Bailo Diallo
    AU  - Jean Marie Kipela
    Y1  - 2023/05/25
    PY  - 2023
    N1  - https://doi.org/10.11648/j.wjph.20230802.25
    DO  - 10.11648/j.wjph.20230802.25
    T2  - World Journal of Public Health
    JF  - World Journal of Public Health
    JO  - World Journal of Public Health
    SP  - 139
    EP  - 147
    PB  - Science Publishing Group
    SN  - 2637-6059
    UR  - https://doi.org/10.11648/j.wjph.20230802.25
    AB  - Coronavirus infectious disease (COVID-19) shows remarkable symptomatic heterogeneity. To date, only a few demographic and clinical factors, such as advanced age, diabetes, and cardiovascular disease, have been associated with poor outcomes and increased risk of mortality from COVID-19. In the Labe region, the lethality of COVID-19 disease remains high in people with comorbidities. In our study, comorbidities were frequently associated with COVID-19 infection and were dominated by hypertension and diabetes. This recognition may help direct efforts toward prevention and management. The objective of the study was to describe the factors associated with mortality in COVID-19 patients with comorbidities hospitalized in the Labe region (Epidemiological Treatment Centers -CT Epi- and home). Methods: The study was carried out in the CT-Epi of COVID-19. It focused on the analysis of 1443 records of patients hospitalized in the CT-Epi of the Labe Region. It was a transversal and analytical study conducted in July 2022. Factors associated with mortality in patients with comorbidities were identified through patient records and content analysis. Results: A total of 1443 patients with COVID-19 hospitalized in the Labe region participated in our study, including 244 with comorbidities and 1199 patients with COVID-19 without comorbidities. Among these patients in our study, 823 were men and 620 were women, i.e., a M/F sex ratio of 1.33. The average age was 45 years (Min= 7 years; Max= 99 years). Bivariate analysis showed that there was a statistically significant association between comorbidities and the occurrence of death in patients with COVID-19. There is a positive association between this risk factor, which is comorbidity, and the occurrence of death. Therefore, we say that comorbidities are risk factors that are responsible for the occurrence of death in patients with COVID-19 in the Labe region. Conclusion: In our study, advanced age, hypertension, diabetes, HIV, and chronic lung disease were the main risk factors for hospitalization or death due to COVID-19 in the Labe region. Further research is needed to identify risk factors associated with severe forms and mortality of COVID-19 to optimize management of patients with comorbidities. This study places particular emphasis on the priority targets (people over 60 and people with co-morbidities) of accelerated vaccination campaigns against COVID-19.
    VL  - 8
    IS  - 2
    ER  - 

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Author Information
  • World Health Organization, WHO Guinea Office, Conakry, Guinea

  • World Health Organization, WHO Guinea Office, Conakry, Guinea

  • Department of Medicine, Faculty of Health Science and Technology, University Gamal Abdel Nasser, Chair of Public Health, Conakry, Guinea

  • Department of Medicine, Faculty of Health Science and Technology, University Gamal Abdel Nasser, Chair of Public Health, Conakry, Guinea

  • World Health Organization, WHO Guinea Office, Conakry, Guinea

  • World Health Organization, WHO Guinea Office, Conakry, Guinea

  • World Health Organization, WHO Guinea Office, Conakry, Guinea

  • World Health Organization, WHO Guinea Office, Conakry, Guinea

  • World Health Organization, WHO Guinea Office, Conakry, Guinea

  • World Health Organization, WHO Guinea Office, Conakry, Guinea

  • World Health Organization, WHO Guinea Office, Conakry, Guinea

  • World Health Organization, WHO Guinea Office, Conakry, Guinea

  • World Health Organization, WHO Guinea Office, Conakry, Guinea

  • Regional Health Directorate of Labe, Labe, Guinea

  • Regional Health Directorate of Labe, Labe, Guinea

  • Regional Health Directorate of Labe, Labe, Guinea

  • Regional Health Directorate of Labe, Labe, Guinea

  • Regional Health Directorate of Labe, Labe, Guinea

  • Regional Health Directorate of Labe, Labe, Guinea

  • Regional Health Directorate of Labe, Labe, Guinea

  • Regional Health Directorate of Labe, Labe, Guinea

  • World Health Organization, WHO Guinea Office, Conakry, Guinea

  • World Health Organization, WHO Guinea Office, Conakry, Guinea

  • World Health Organization, WHO Guinea Office, Conakry, Guinea

  • World Health Organization, WHO Guinea Office, Conakry, Guinea

  • World Health Organization, Dakar Office, Dakar, Senegal

  • World Health Organization, WHO Guinea Office, Conakry, Guinea

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