| Peer-Reviewed

Effect of Coix Seed (Coix lacryma-jobi L.) and Rice Bean (Vigna umbellata) Soup on the Level of Serum Index and IL-6 in Mice Hyperlipemia Model

Received: 15 December 2019    Accepted: 29 April 2020    Published: 16 June 2020
Views:       Downloads:
Abstract

Objective: In order to explore the effect of Chinese medicinal diet Coix Seed and Red Bean Soup on sveral serum indexs of hypolipidemic mice; MethodsM: ice were used as model animals to explore the effect of Chinese diet Coix seed (Coix lacryma-jobi L.) and rice bean (Vigna umbellata) Soup; Mice bodies weight, organs and blood lipid level and other aspects of mice were observed. Results: (1) The level of triglyceride (TG) and total cholesterol (TCHO) in the medication group was lower than that in the model group, but the difference was not significant. (2) In liver index, there was a significant difference between low dose group and model group (P < 0.01); in spleen index, there was a significant difference between low dose group and model group (P < 0.01). (3) The atherosclerosis index (AI) of each experimental group was significantly lower than that of the model group. (4) The NO content in the low dose experimental group was 17.28 micromol/L, which was significantly higher than that in the model group (11.25 micromol/L). NO had a protective effect on blood vessels. (5) the soup can up-regulate IL-6 cytokines: Conclusion: the medicinal soup have some function of lipid regulation and can protect the vascular intima and important organs function.

Published in Asia-Pacific Journal of Food Science and Technology (Volume 2, Issue 1)
Page(s) 6-10
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Coix Seed and Rice Bean Soup, Hyperlipidemia, Lipid Levels

References
[1] 本刊编辑部. 健脾渗湿的佳品——薏米红豆粥[J]. 求医问药,2008(08):49。
[2] 赵为武,李俊,郭晓关,等. 薏苡仁提取油的成分分析[J]. 安徽农业科学,2014(1):257~258, 305。
[3] 重用薏苡仁治疗痰湿型头痛/重用薏苡仁治疗乳腺小叶增生/薏苡仁治疗肠粘连有效[J]. 中医杂志,2011,52(5):432。
[4] 刘雨晴,梁婧,杨梓晨,等. 薏苡仁的药理作用研究进展[J]. 安徽农业科学,2010,38(20):10678, 10686。
[5] 陶小军,雷雪霏,李云兴,等. 薏苡仁油的镇痛止血作用[J]. 中国实验方剂学杂志,2010,16(17):161~163。
[6] 崔建忠,张汉武. 历代医者论红豆,祛病强身促长寿[J]. 健康生活,2015(10):45。
[7] 王希杰. 赤豆、红豆、相思豆——词语和概念漫话[J]. 语文学习,1982(08):55~56。
[8] 李经纬. 中医大辞典[J]. 2004:767, 762, 599, 1062~1063, 526, 420。
[9] 吴志嵩,路新国. 山楂山药汤对高脂血症小鼠体质量和血脂水平的影响[J]. 西部中医药,2012(02):15~17。
[10] 胡文兵,赵静,陈婷婷,等. 青钱柳多糖对高脂血症小鼠的降血脂作用及机制初探[J]. 现代食品科技,2015,31(11):39~44。
[11] 张晓磊,武岩峰,朴春红,等. 益生菌发酵豆乳对高脂血症小鼠降血脂及肝损伤缓解的作用[J]. 现代食品科技,2016,32(05):1~8。
[12] 苏方方,高建芸,王桂英,等. 45℃艾灸对高脂血症大鼠血脂及血清ox-LDL、NO的影响[J]. 中国针灸,2019,39(02):180~184。
[13] 高尔,王金红,李洪军,等. 乳化葛根素对高脂血症家兔血清NO及PGI_2的影响[J]. 潍坊医学院学报,2001(01):1~3。
[14] 唐晓伟,鲁亚平. 细胞间信息传递介质——NO研究进展[J]. 生物学教学,2005(06):7~9。
[15] 汤艳,易健,彭千元,等. 黑茶对高脂血症大鼠血脂及炎症因子TNF-α、IL-6影响[J]. 辽宁中医药大学学报,2016,18(09):25~28。
[16] 王冲,刘欣,李豪,等. 牙周基础治疗对伴高脂血症牙周炎大鼠血清IL-6及牙槽骨吸收影响的研究[J]. 口腔医学研究,2016,32(08):785~788。
[17] 吴建龙,刘鹏鹰,吴晔良,等. 2型糖尿病并高脂血症患者血清IL-6、血浆纤维蛋白原水平分析[J]. 广州医药,1999(05):16~17。
[18] 王祚克,曾庆宁,王健,降脂通脉汤内服联合大黄敷脐治疗冠心病伴高血脂症疗效及对血清Hcy、IL-6、APN和血脂指标的影响[J]. 现代中西医结合杂志,2019(14):1523~1526。
Cite This Article
  • APA Style

    Ma Guangqiang, Niu Ling, Wan Hongjiao, Ding Chenghua, Ye Heping, et al. (2020). Effect of Coix Seed (Coix lacryma-jobi L.) and Rice Bean (Vigna umbellata) Soup on the Level of Serum Index and IL-6 in Mice Hyperlipemia Model. Asia-Pacific Journal of Food Science and Technology, 2(1), 6-10.

    Copy | Download

    ACS Style

    Ma Guangqiang; Niu Ling; Wan Hongjiao; Ding Chenghua; Ye Heping, et al. Effect of Coix Seed (Coix lacryma-jobi L.) and Rice Bean (Vigna umbellata) Soup on the Level of Serum Index and IL-6 in Mice Hyperlipemia Model. Asia-Pac. J. Food Sci. Technol. 2020, 2(1), 6-10.

    Copy | Download

    AMA Style

    Ma Guangqiang, Niu Ling, Wan Hongjiao, Ding Chenghua, Ye Heping, et al. Effect of Coix Seed (Coix lacryma-jobi L.) and Rice Bean (Vigna umbellata) Soup on the Level of Serum Index and IL-6 in Mice Hyperlipemia Model. Asia-Pac J Food Sci Technol. 2020;2(1):6-10.

    Copy | Download

  • @article{10045619,
      author = {Ma Guangqiang and Niu Ling and Wan Hongjiao and Ding Chenghua and Ye Heping and Zheng Lixiang},
      title = {Effect of Coix Seed (Coix lacryma-jobi L.) and Rice Bean (Vigna umbellata) Soup on the Level of Serum Index and IL-6 in Mice Hyperlipemia Model},
      journal = {Asia-Pacific Journal of Food Science and Technology},
      volume = {2},
      number = {1},
      pages = {6-10},
      url = {https://www.sciencepublishinggroup.com/article/10045619},
      abstract = {Objective: In order to explore the effect of Chinese medicinal diet Coix Seed and Red Bean Soup on sveral serum indexs of hypolipidemic mice; MethodsM: ice were used as model animals to explore the effect of Chinese diet Coix seed (Coix lacryma-jobi L.) and rice bean (Vigna umbellata) Soup; Mice bodies weight, organs and blood lipid level and other aspects of mice were observed. Results: (1) The level of triglyceride (TG) and total cholesterol (TCHO) in the medication group was lower than that in the model group, but the difference was not significant. (2) In liver index, there was a significant difference between low dose group and model group (P < 0.01); in spleen index, there was a significant difference between low dose group and model group (P < 0.01). (3) The atherosclerosis index (AI) of each experimental group was significantly lower than that of the model group. (4) The NO content in the low dose experimental group was 17.28 micromol/L, which was significantly higher than that in the model group (11.25 micromol/L). NO had a protective effect on blood vessels. (5) the soup can up-regulate IL-6 cytokines: Conclusion: the medicinal soup have some function of lipid regulation and can protect the vascular intima and important organs function.},
     year = {2020}
    }
    

    Copy | Download

  • TY  - JOUR
    T1  - Effect of Coix Seed (Coix lacryma-jobi L.) and Rice Bean (Vigna umbellata) Soup on the Level of Serum Index and IL-6 in Mice Hyperlipemia Model
    AU  - Ma Guangqiang
    AU  - Niu Ling
    AU  - Wan Hongjiao
    AU  - Ding Chenghua
    AU  - Ye Heping
    AU  - Zheng Lixiang
    Y1  - 2020/06/16
    PY  - 2020
    T2  - Asia-Pacific Journal of Food Science and Technology
    JF  - Asia-Pacific Journal of Food Science and Technology
    JO  - Asia-Pacific Journal of Food Science and Technology
    SP  - 6
    EP  - 10
    PB  - Science Publishing Group
    UR  - http://www.sciencepg.com/article/10045619
    AB  - Objective: In order to explore the effect of Chinese medicinal diet Coix Seed and Red Bean Soup on sveral serum indexs of hypolipidemic mice; MethodsM: ice were used as model animals to explore the effect of Chinese diet Coix seed (Coix lacryma-jobi L.) and rice bean (Vigna umbellata) Soup; Mice bodies weight, organs and blood lipid level and other aspects of mice were observed. Results: (1) The level of triglyceride (TG) and total cholesterol (TCHO) in the medication group was lower than that in the model group, but the difference was not significant. (2) In liver index, there was a significant difference between low dose group and model group (P < 0.01); in spleen index, there was a significant difference between low dose group and model group (P < 0.01). (3) The atherosclerosis index (AI) of each experimental group was significantly lower than that of the model group. (4) The NO content in the low dose experimental group was 17.28 micromol/L, which was significantly higher than that in the model group (11.25 micromol/L). NO had a protective effect on blood vessels. (5) the soup can up-regulate IL-6 cytokines: Conclusion: the medicinal soup have some function of lipid regulation and can protect the vascular intima and important organs function.
    VL  - 2
    IS  - 1
    ER  - 

    Copy | Download

Author Information
  • College of Chinese Traditional Medicine, Jiangxi University of Chinese Traditional Medicine, Nanchang, China

  • College of Chinese Traditional Medicine, Jiangxi University of Chinese Traditional Medicine, Nanchang, China

  • College of Chinese Traditional Medicine, Jiangxi University of Chinese Traditional Medicine, Nanchang, China

  • College of Chinese Traditional Medicine, Jiangxi University of Chinese Traditional Medicine, Nanchang, China

  • College of Chinese Traditional Medicine, Jiangxi University of Chinese Traditional Medicine, Nanchang, China

  • College of Chinese Traditional Medicine, Jiangxi University of Chinese Traditional Medicine, Nanchang, China

  • Sections