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Head and Neck Lymphomas in Jos University Teaching Hospital Nigeria: A Five Year Review
Nimkur Lohpon Tonga,
Obebe Francis Ameh,
Okoye Chukwuma,
John Emmanuel
Issue:
Volume 8, Issue 1, March 2023
Pages:
1-4
Received:
8 September 2022
Accepted:
24 October 2022
Published:
20 March 2023
Abstract: Introduction: Lymphomas are heterogeneous group of lymphoid tissues traditionally categorized as either Hodgkin’s Lymphoma (HL) or Non-Hodgkin’s Lymphoma (NHL). The head and neck region is rich in lymphoid tissues, thus a fertile anatomic site for the development of lymphoid proliferative diseases like lymphomas. In the head and neck, malignant lymphomas account for 5% of all malignant neoplasm; Non-Hodgkin’s Lymphoma (NHL) is the most common accounting for 75%. The clinical behaviour and manifestations of Lymphomas in the head and neck lack specific characteristics that would enable attribution to a specific lymphoma entity without biopsy and histological evidence. Materials and Methods: It is a 5 year retrospective study of confirmed histopathological analysis of head and neck lymphomas from 1st January 2017 to31st December 2021. Case notes of all histopathologically confirmed head and neck lymphomas were retrieved from the medical records department and also theatre records as supportive data were analysed for age, sex, histological diagnosis, tumour site, duration of symptoms before presentation and treatment modality; and then discussed. Results:-The total number of patients seen during the period under review was 1678, 16 patients had histopathologically confirmed lymphomas out of 388 patients with head and neck tumours, thus prevalence of 0.1% and 4.1% of all head and neck tumours. Male to Female ratio of 5:1, age range of 4 to 62 years, mean age of 29 years. Most common tumour site is the cervical region-315; the most frequently seen histological type is the Non Hodgkin’s lymphoma (NHL) and the most common duration of symptom before presentation is over 1 year-50%. All patients had chemotherapy as a treatment modality. Conclusion: This study reveals the management challenges of the head and neck lymphomas are due to late presentation, financial constraints and ignorance. Health awareness and adequate Health Insurance Policy are needed to cope or mitigate these problems.
Abstract: Introduction: Lymphomas are heterogeneous group of lymphoid tissues traditionally categorized as either Hodgkin’s Lymphoma (HL) or Non-Hodgkin’s Lymphoma (NHL). The head and neck region is rich in lymphoid tissues, thus a fertile anatomic site for the development of lymphoid proliferative diseases like lymphomas. In the head and neck, malignant lym...
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A Clinical Case Report About an Intracranial Lipoma
Issue:
Volume 8, Issue 1, March 2023
Pages:
5-10
Received:
10 February 2023
Accepted:
8 March 2023
Published:
20 March 2023
Abstract: Intracranial lipoma is a uncommon congenital malformation, represent less than 0.1% of all intracranial tumors. Result from abnormal persistence and mal-differentiation of meninx primitiva, during embryogenesis. The cases in which the tumor presents an extracranial component are caused by a secondary dehiscence of the skull with evagination of a small tuft of primitive meninges. These lesions are frequently located in the inter-hemispheric fissure in the pericallosal region in 50% of cases, other locations as ambient or quadrigeminal cisterns present an incidence about 20-25%. In half of cases the patients present associate midline brain malformations of varying severity, the most frequent is the agenesia of the corpus callosus. The most accepted theory states that in embryonic phases, mesenchymal alterations at the level of the cranial sutures in the sagittal plane can cause anomalies of the SSS, sinus rectum, tentorium, and parietal bones that would explain the associated anomalies. Majority of intracranial lipomas are detected incidentally, being a third of the asymptomatic cases. As in all other pathologies certain localizations cause specific symptomatology of the involved area. The most common clinical manifestations are headache, epilepsy, mental dysfunctions and cranial nerve deficits. The clinical diagnosis is unclear and it is necessary release complementary exams in every suspected cases. Neuroimaging studies such as computed tomography (CT) or magnetic resonance imaging (MRI) make possible identify these lesions. We describe a clinical case about a 79-year-old woman with headache without any other symptoms. Was done CT and MRI that showed a inter-hemispheric lesion located in the pericallosal region, without any other abnormality associated. The development, during the last decades, of neuroimaging and histogenesis techniques increased the knowledge about this pathology and modified the management in recent times. The surgery is contraindicated in the majority of the cases, however still play a role in some cases especially in presence of hydrocephalus, uncontrollable seizures, and bony affectation with cosmetic influence. The medical control of the epilepsy is mandatory. We present a clinical case about pericallosal intracranial lipoma and review the current literature. Taking in account the clinical situation and the imaging findings, we decide for a conservative approach with clinical/neurological and radiological follow-up.
Abstract: Intracranial lipoma is a uncommon congenital malformation, represent less than 0.1% of all intracranial tumors. Result from abnormal persistence and mal-differentiation of meninx primitiva, during embryogenesis. The cases in which the tumor presents an extracranial component are caused by a secondary dehiscence of the skull with evagination of a sm...
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Analysis of the Characteristics of Colorectal Cancer or Malignant Colorectal Tumors Transferred to Other Organs: A Population-Based Study
Issue:
Volume 8, Issue 1, March 2023
Pages:
11-19
Received:
14 March 2023
Accepted:
30 March 2023
Published:
11 April 2023
Abstract: Advanced colorectal cancer and malignant tumors metastasize other organs, which seriously threaten human health. Such patients have a low five-year survival rate and poor quality of life. Therefore, it is necessary to study such patients. There is still a long way to go for doctors. Our study uses retrospective research methods to statistically analyze the metastasis of colorectal cancer and other organs and tissues metastasis of colorectal malignant tumors. Let's pay full attention to such patients. Because the treatment recommended by many clinicians in the later stage is different. Some doctors recommend active treatment. Some doctors recommend giving up treatment. Therefore, this study aims to make doctors pay attention to the treatment and treatment process of advanced colorectal cancer and colorectal malignant tumors metastasis of other organs in the later stage, so as to improve the survival rate of patients and improve the quality of life of patients. Research background: At present, colorectal cancer or colorectal malignant tumors seriously endanger human health around the world. The main reason is our insufficient understanding of colorectal cancer. We don't attach importance to health education. We have insufficient preventive measures for intestinal cancer and the promotion of risk factors, and the inadequacy of early screening for intestinal cancer, so that some patients are late tumors when colorectal cancer is found. At the same time, patients with such tumors are prone to the invasion of peripheral tissues or the transfer of tumors to surrounding tissues and organs. The survival rate of patients has been greatly reduced. Objective: To improve the 5-year survival rate of patients with advanced colorectal cancer or malignant colorectal tumor and improve their quality of life. Our research on this kind of patients is meaningful. Research method: We use retrospective research. In CNKI and PubMed public database, the number of studies and cases on the transfer of colorectal cancer or colorectal malignant tumors to other organs from 2020 to 2023 were statistically retrieved, and finally analyzed. Organs include: brain, lung, liver, pancreas, kidney, uterus, ovaries and bones. Included criteria: colorectal cancer or colorectal malignant tumors, brain metastasis, lung metastasis, liver metastasis, pancreatic metastasis, kidney metastasis, uterine metastasis, ovarian metastasis, bone metastasis. Results: The most common metastasis of colorectal cancer in this study is the liver (47.2%), bone (34.9%), lung (7.5%), ovarian and vagina (6.1%), brain (4.3%). Pancreas, kidneys and uterus are relatively rare, but there are still clinical reports.
Abstract: Advanced colorectal cancer and malignant tumors metastasize other organs, which seriously threaten human health. Such patients have a low five-year survival rate and poor quality of life. Therefore, it is necessary to study such patients. There is still a long way to go for doctors. Our study uses retrospective research methods to statistically ana...
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