American Journal of Clinical and Experimental Medicine

Volume 7, Issue 4, July 2019

  • HIF-1α Was a Key Regulator to Improve hBMSCs to Secrete Vascular Endothelial Cytokine with Astragaloside in Hypoxia

    Ji Hong Hu, Jin Hua, Jia Jia, Lu Juan, Jing Miao Zhao, Shu Xia Wang, Yun Wang, Li Mei Jin, Jin Juan Li

    Issue: Volume 7, Issue 4, July 2019
    Pages: 75-82
    Received: 01 August 2019
    Accepted: 06 September 2019
    Published: 23 September 2019
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    Abstract: This study aimed to assess the combined therapeutic efficacies with gene therapy and stem cell treatment and herb on the differentiation of hBMSCs into vascular endothelial cells under hypoxia condition. The third passage of hBMSCs were randomly divided into four groups, including control group (hBMSCs transfected with empty vectors), VEGF group (V... Show More
  • Research Progress of Th17/Treg Cells and Their Transcription Factors in Autoimmune Diseases

    Zhenjiang Hou, Zhaoxin Mu, Cuicui Wang

    Issue: Volume 7, Issue 4, July 2019
    Pages: 83-92
    Received: 09 July 2019
    Accepted:
    Published: 27 September 2019
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    Abstract: Helper T cell 17 (Th17) being a new cell subset of CD4+T in the body, which is different from Th1 and Th2 cells, have independent mechanisms of differentiation and developmental regulation. Th17 cells mainly secrete various cytokines such as IL-17, IL-6 and TNF-α, which induce inflammation. Treg cells are T cells with high expression of CD25 differ... Show More
  • Relationship Between No/Slow Reflow Phenomenon in Acute Myocardial Infarction Patients After Percutaneous Coronary Intervention and Inflammatory Response

    Binbin Wang, Zhi Xiao, Nana Peng

    Issue: Volume 7, Issue 4, July 2019
    Pages: 93-96
    Received: 26 August 2019
    Accepted:
    Published: 27 September 2019
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    Abstract: Background: To explore the relationship between the occurrence of no/slow reflow phenomenon in acute myocardial infarction patients after undergoing percutaneous coronary intervention (PCI) and inflammatory response. Objective: Prospective study was conducted on 519 acute myocardial infarction patients undergoing PCI, in which 509 patients were fol... Show More