Determination of Five Sulfonamides in Water by High Performance Liquid Chromatography Combined with Ionic Liquid Liquid-liquid Microextraction
American Journal of Applied Chemistry
Volume 8, Issue 3, June 2020, Pages: 89-93
Received: Jun. 4, 2020; Accepted: Jun. 24, 2020; Published: Jul. 28, 2020
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Authors
Gao Yuling, College of Agriculture, Heilongjiang Bayi Agricultural University, Daqing, China; Agricultural Products and Procesed Products Supervision and Testing Center, Ministry of Agriculture, Daqing, China
Liang Ting, Agricultural and rural area Bureau of Daiyue District, Tai'an City, Taian, China
Sun Peng, College of Agriculture, Heilongjiang Bayi Agricultural University, Daqing, China; Agricultural Products and Procesed Products Supervision and Testing Center, Ministry of Agriculture, Daqing, China
Guo Yongxia, College of Agriculture, Heilongjiang Bayi Agricultural University, Daqing, China
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Abstract
A novel method for the determination of sulfamethazine (SM2), sulfamonomethoxinc (SMM), sulfamethoxazole (SMZ), sulfadiazine (SD), sulfaquinoxaline (SQX) from the water has been developed using ionic liquid dispersive 1iquid-liquid microextraction coupled with high performance liquid chromatography. The influence of extraction parameters including types of extraction solvent, volume of extraction solvent, types of dispersant solvent, volume of dispersant solvent, extraction time, and pH were investigated. Using 80 μL 1-Hexyl-3-methylimidazolium hexafluorophosphate ([C6MIM]PF6) as extraction solvent, 800 μL acetonitrile as dispersant solvent, pH=4.0, extraction 3min, centrifugal after storage 2min. Under the optima1 conditions, good linear relationships were obtained in the five sulfonamides residues concentrations of 5~150 μg•L-2 with the correlation coefficients of 0.9988-0.9994, limits of detection (LOD) were 0.74~1.21 μg•L-2 (S/N=3), limits of quantification (LOQ) were 2.51~4.06 μg•L-2 (S/N=10). The proposed method was applied to the determination of five sulfonamides residues in water, the recoveries were from 88.5% to 98.8%, with the corresponding intra-day RSDs less than 5.1%, inter-day RSDs less than 9.5%. The method was considered to be simple, fast, and precise to satisfy the requirements of the residual analysis of sulfonamides in water.
Keywords
Ionic Liquid, Dispersive Liquid-liquid Microextraction, High Performance Liquid Chromatography, Water
To cite this article
Gao Yuling, Liang Ting, Sun Peng, Guo Yongxia, Determination of Five Sulfonamides in Water by High Performance Liquid Chromatography Combined with Ionic Liquid Liquid-liquid Microextraction, American Journal of Applied Chemistry. Vol. 8, No. 3, 2020, pp. 89-93. doi: 10.11648/j.ajac.20200803.14
Copyright
Copyright © 2020 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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