Determination of Five Sulfonamides in Water by High Performance Liquid Chromatography Combined with Ionic Liquid Liquid-liquid Microextraction
American Journal of Applied Chemistry
Volume 8, Issue 3, June 2020, Pages: 89-93
Received: Jun. 4, 2020;
Accepted: Jun. 24, 2020;
Published: Jul. 28, 2020
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Gao Yuling, College of Agriculture, Heilongjiang Bayi Agricultural University, Daqing, China; Agricultural Products and Procesed Products Supervision and Testing Center, Ministry of Agriculture, Daqing, China
Liang Ting, Agricultural and rural area Bureau of Daiyue District, Tai'an City, Taian, China
Sun Peng, College of Agriculture, Heilongjiang Bayi Agricultural University, Daqing, China; Agricultural Products and Procesed Products Supervision and Testing Center, Ministry of Agriculture, Daqing, China
Guo Yongxia, College of Agriculture, Heilongjiang Bayi Agricultural University, Daqing, China
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A novel method for the determination of sulfamethazine (SM2), sulfamonomethoxinc (SMM), sulfamethoxazole (SMZ), sulfadiazine (SD), sulfaquinoxaline (SQX) from the water has been developed using ionic liquid dispersive 1iquid-liquid microextraction coupled with high performance liquid chromatography. The influence of extraction parameters including types of extraction solvent, volume of extraction solvent, types of dispersant solvent, volume of dispersant solvent, extraction time, and pH were investigated. Using 80 μL 1-Hexyl-3-methylimidazolium hexafluorophosphate ([C6MIM]PF6) as extraction solvent, 800 μL acetonitrile as dispersant solvent, pH=4.0, extraction 3min, centrifugal after storage 2min. Under the optima1 conditions, good linear relationships were obtained in the five sulfonamides residues concentrations of 5~150 μg•L-2 with the correlation coefficients of 0.9988-0.9994, limits of detection (LOD) were 0.74~1.21 μg•L-2 (S/N=3), limits of quantification (LOQ) were 2.51~4.06 μg•L-2 (S/N=10). The proposed method was applied to the determination of five sulfonamides residues in water, the recoveries were from 88.5% to 98.8%, with the corresponding intra-day RSDs less than 5.1%, inter-day RSDs less than 9.5%. The method was considered to be simple, fast, and precise to satisfy the requirements of the residual analysis of sulfonamides in water.
Ionic Liquid, Dispersive Liquid-liquid Microextraction, High Performance Liquid Chromatography, Water
To cite this article
Determination of Five Sulfonamides in Water by High Performance Liquid Chromatography Combined with Ionic Liquid Liquid-liquid Microextraction, American Journal of Applied Chemistry.
Vol. 8, No. 3,
2020, pp. 89-93.
Copyright © 2020 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/
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Yinming Fan, Guolong Zeng, Xiaoguo Ma. Effects of prepolymerization on surface molecularly imprinted polymer for rapid separation and analysis of sulfonamides in water [J]. Journal of Colloid and Interface Science, 2020, 5711: 21-29.
Yeliz Demir, Zeynep Köksal. The inhibition effects of some sulfonamides on human serum paraoxonase-1 (hPON1) [J]. Pharmacological Reports, 2019, 71: 545-549.
Codex Alimentarius Commossion. CAC/MRL 02-2005: 21 [Z].
European Agency for the Evaluation of Medicinal Products. EMEA/MRL/878/03- FINAL, Metamizole summary report [R]. London: The European Agency for the Evaluation of Medicinal Products, 2003.
Announcement No. 235 [Z] of the Ministry of agriculture of the people's Republic of China.
H Sereshti, M Khosraviani, MS Amini-Fazl. Miniaturized salting-out liquid-liquid extraction in a coupled-syringe system combined with HPLC-UV for extraction and determination of sulfanilamide [J]. Talanta, 2014, 121: 199-204.
W Yu, K Li, ZL Liu, et al. Novelty aqueous two-phase extraction system based on ionic liquid for determination of sulfonamides in blood coupled with high-performance liquid chromatography [J]. Microchemical Journal, 2018, 136: 263-269.
Jiangyi Wu, Yanyun Li, Weicheng Li, Zhenbin Gong, Xiaojia Huang. Preparation of a novel monolith-based adsorbent for solid-phase microextraction of sulfonamides in complex samples prior to HPLC-MS/MS analysis [J]. Analytica Chimica Acta, 2020, 111829: 9-17.
Carolina Nebot, Patricia Regal, Jose Manuel Miranda, Cristina Fente, Alberto Cepeda. Rapid method for quantification of nine sulfonamides in bovine milk using HPLC/MS/MS and without using SPE [J]. Food Chemistry, 2013, 141 (31): 2294-2299.
G Font, A Juan-García, Y Picó. Pressurized liquid extraction combined with capillary electrophoresis-mass spectrometry as an improved methodology for the determination of sulfonamide residues in meat [J]. Journal of Chromatography A, 2007, 1159 (1-23): 233-241.
LR Yang, SJ Zhou, YZ Xiao, et al. Sensitive simultaneous determination of three sulfanilamide artificial sweeters by capillary electrophoresis with on-line preconcentration and contactless conductivity detection [J]. Food Chemistry, 2015, 1881: 446-451.
Sun Peng, Qiao Sshi, Guo Xiujuan. Determination of enrofloxacin and ciprofloxacin in liquid milk by using ionic liquid-based dispersive liquid-phase microextraction coupled with HPLC [J]. Chin. J. Pharm. Anal., 2017, 37: 111-116.
Sun Peng, Gao Yuling, Wang Shuang, et al. Determination of enrofloxacin and ciprofloxacin in liquid milk by using ionic liquid-based dispersive liquid-phase microextraction coupled with high performance liquid chromatography [J] Chemical Reagent, 2016, 38: 999-1002.
AV Herrera-Herrera, J Hernández-Borges, MM Afonso, et al. Comparison between magnetic and non magnetic multi-walled carbon nanotubes-dispersive solid-phase extraction combined with ultra-high performance liquid chromatography for the determination of sulfonamide antibiotics in water samples [J]. Talanta, 2013, 1161: 695-703.
NE Markina, AV Markin, K Weber, et al. Liquid-liquid extraction-assisted SERS-based determination of sulfamethoxazole in spiked human urine [J]. Analytica Chimica Acta, 2020, 1109: 61-68.
LKadziński, RBanasiuk, B Banecki. Determination of ten sulfonamides in honey using tetrahydrofuran Salting Out Liquid Liquid Extraction and monolithic silica column [J]. LWT, 2018, 96: 7-12.
P Sun, YL Gao, YF Lian. Determination of eugenol in aquatic products by dispersive solid-phase extraction and ultra-high-performance liquid chromatography-tandem mass spectrometry, Food Anal. Methods, 2017, 10: 3217-3224.
P Sun, YL Gao, C Xu, et al. Determination of seven pyrethroid pesticides residue in vegetable samples by gas chromatography using carboxylated multi-walled carbon nanotubes as dispersion solid phase extraction sorbent, Food Additives & Contaminants: Part A, 2017, 34 (12): 2164-2172.