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Evaluation of Biological Approaches of Green Synthesized MgO Nanoparticles by Syzygium aromaticum

Green synthesis approaches are acquiring importance due to their environmentally safe, commercial scalability, versatility, cost-effectiveness, simplicity and efficiency in large scale synthesis. Spice extract consist of numerous biochemical and phytochemical compounds that serve as capping and reducing agent that facilitates the production of non-toxic nanoparticles that are useful for pharmaceutical and biological applications. In the present study, MgO nanoparticles were successfully synthesized by the use of extract of Syzygium aromaticum. FTIR, SEM, XRD, EDX and UV visible were used for the characterization of MgO nanoparticles. The absorbance at 480nm from UV-visible spectroscopy shows the establishment of MgO nanoparticles. The FTIR results indicated the presence of functional groups responsible for the formation of nanoparticles and the peak between 549.71 and 489.92 cm-1 confirm the presence of magnesium oxide. The average particle size of MgO nanoparticles is 16nm which is confirmed by XRD. Scherer formula was used to calculate the average crystallite size of MgO nanoparticles. EDX analysis revealed the elemental composition. The phytochemical analysis of extract of Syzygium aromaticum performed and their analysis showed the presence of Phytoconstituents. The antifungal activity of prepared MgO nanoparticles was investigated by Disc diffusion method. Results showed the highest activity against A. parasiticus (24 mm DIZ). Overall results of the present study showed green synthesized MgO nanoparticles possess potent antifungal activity.

Magnesium Oxide Nanoparticles, Green Synthesis, Characterization, Antifungal Activity

APA Style

Muneeza Munir, Syeda Mona Hassan, Shahzad Sharif Mughal, Alvina Rafiq. (2022). Evaluation of Biological Approaches of Green Synthesized MgO Nanoparticles by Syzygium aromaticum. International Journal of Atmospheric and Oceanic Sciences, 6(2), 44-53.

ACS Style

Muneeza Munir; Syeda Mona Hassan; Shahzad Sharif Mughal; Alvina Rafiq. Evaluation of Biological Approaches of Green Synthesized MgO Nanoparticles by Syzygium aromaticum. Int. J. Atmos. Oceanic Sci. 2022, 6(2), 44-53. doi: 10.11648/j.ijaos.20220602.12

AMA Style

Muneeza Munir, Syeda Mona Hassan, Shahzad Sharif Mughal, Alvina Rafiq. Evaluation of Biological Approaches of Green Synthesized MgO Nanoparticles by Syzygium aromaticum. Int J Atmos Oceanic Sci. 2022;6(2):44-53. doi: 10.11648/j.ijaos.20220602.12

Copyright © 2022 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License ( which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

1. Amin, M., Jassal, M., & Tygi, S. (2013). Phytochemical screening and isolation of eugenol from Syzygium aromaticum by gas chromatography. International Journal of Research in Phytochemistry and Pharmacology, 3 (1), 74-77.
2. Bar, H., Bhui, D. K., Sahoo, G. P., Sarkar, P., De, S. P., & Misra, A. (2009). Green synthesis of silver nanoparticles using latex of Jatropha curcas. Colloids and surfaces A: Physicochemical and engineering aspects, 339 (1-3), 134-139.
3. Claesson, P. M., Ederth, T., Bergeron, V., & Rutland, M. (1996). Techniques for measuring surface forces. Advances in colloid and interface science, 67, 119-183.
4. Cummings, J., & Stephen, A. (2007). Carbohydrate terminology and classification. European journal of clinical nutrition, 61 (1), S5-S18.
5. Dobrucka, R. (2018). Synthesis of MgO nanoparticles using Artemisia abrotanum herba extract and their antioxidant and photocatalytic properties. Iranian Journal of Science and Technology, Transactions A: Science, 42 (2), 547-555.
6. El Shafey, A. M. (2020). Green synthesis of metal and metal oxide nanoparticles from plant leaf extracts and their applications: A review. Green Processing and Synthesis, 9 (1), 304-339.
7. Evans, W. (2005). Trease and Evans Pharmacognosy 15 edn. Division of Reed Elsevier India Pvt. Ltd., New Delhi, India, ISBN-13, 978-981.
8. Fischer, D. C. H., de Amorim Gualda, N. C., Bachiega, D., Carvalho, C. S., Lupo, F. N., Bonotto, S. V.,... Avila, P. E. (2004). In vitro screening for antiplasmodial activity of isoquinoline alkaloids from Brazilian plant species. Acta Tropica, 92 (3), 261-266.
9. Gibson, A., Haydock, R., & LaFemina, J. P. (1992). Electronic structure and relative stability of the MgO (001) and (111) surfaces. Journal of Vacuum Science & Technology A: Vacuum, Surfaces, and Films, 10 (4), 2361-2366.
11. Hussain, S., Jha, P., Chouksey, A., Raman, R., Islam, S., Islam, T., & Choudhary, P. (2011). Spectroscopic investigation of modified single wall carbon nanotube (SWCNT). Journal of Modern Physics, 2 (06), 538.
12. Iravani, S. (2011). Green synthesis of metal nanoparticles using plants. Green Chemistry, 13 (10), 2638-2650.
13. Jhansi, K., Jayarambabu, N., Reddy, K. P., Reddy, N. M., Suvarna, R. P., Rao, K. V.,... Rajendar, V. (2017). Biosynthesis of MgO nanoparticles using mushroom extract: effect on peanut (Arachis hypogaea L.) seed germination. 3 Biotech, 7 (4), 263.
14. Joshi, N. C., SINgH, A., & Rajput, H. (2018). Utilization of Waste Leaves Biomass of Myrica esculenta for the Removal of Pb (II), Cd (II) and Zn (II) ions from Waste Waters. Oriental Journal of Chemistry, 34 (5), 2548.
15. Kassab, R. B., & Bauomy, A. A. (2014). The neuroprotective efficency of the aqueous extract of clove (Syzygium‎ aromaticum) in aluniniuminduced neurotoxicity. Int J Pharm Pharm Sci, 6 (5), 503-508.
16. Krajcovicova-Kudlackova, M., Babinska, K., & Valachovicova, M. (2005). Health benefits and risks of plant proteins. Bratislavske lekarske listy, 106 (6/7), 231.
17. Makarov, V., Love, A., Sinitsyna, O., Makarova, S., Yaminsky, I., Taliansky, M., & Kalinina, N. (2014). “Green” nanotechnologies: synthesis of metal nanoparticles using plants. Acta Naturae (англоязычная версия), 6 (1 (20)).
18. Malik, E. M., & Müller, C. E. (2016). Anthraquinones as pharmacological tools and drugs. Medicinal research reviews, 36 (4), 705-748.
19. Michałowicz, J., & Duda, W. (2007). Phenols--Sources and Toxicity. Polish Journal of Environmental Studies, 16 (3).
20. Mohanpuria, P., Rana, N. K., & Yadav, S. K. (2008). Biosynthesis of nanoparticles: technological concepts and future applications. Journal of nanoparticle research, 10 (3), 507-517.
21. Nakkala, J. R., Mata, R., & Sadras, S. R. (2016). The antioxidant and catalytic activities of green synthesized gold nanoparticles from Piper longum fruit extract. Process Safety and Environmental Protection, 100, 288-294.
22. Nyarko, A. A., & Addy, M. E. (1990). Effect of aqueous extract of Adenia cissampeloides on blood pressure and serum analytes of hypertensive patients. Phytotherapy Research, 4 (1), 25-28.
23. Palanisamy, G., & Pazhanivel, T. (2017). Green synthesis of MgO nanoparticles for antibacterial activity. International research journal of engineering and technology, 4 (9), 137-1.
24. Sarfraz, S., Javed, A., Mughal, S. S., Bashir, M., Rehman, A., Parveen, S.,... & Khan, M. K. (2020). Copper Oxide Nanoparticles: Reactive Oxygen Species Generation and Biomedical Applications. Int. J. Comput. Theor. Chem, 8, 40-46.
25. Rafique, S., Hassan, S. M., Mughal, S. S., Hassan, S. K., Shabbir, N., Perveiz, S.,... & Farman, M. (2020). Biological attributes of lemon: a review. Journal of Addiction Medicine and Therapeutic Science, 6 (1), 030-034.
26. Hanif, M. A., Hassan, S. M., Mughal, S. S., Rehman, A., Hassan, S. K., Ibrahim, A., & Hassan, H. (2021). An overview on ajwain (Trachyspermum Ammi) pharmacological effects: current and conventional. Technology, 5 (1), 1-6.
27. Khalid, Z., Hassan, S. M., Mughal, S. S., Hassan, S. K., & Hassan, H. (2021). Phenolic Profile and Biological Properties of Momordica charantia'. Chemical and Biomolecular Engineering, 6 (1), 17.
28. Hassan, S. M., Mughal, S. S., Hassan, S. K., Ibrahim, A., Hassan, H., Shabbir, N.,... & Shafiq, S. (2020). Cellular interactions, metabolism, assessment and control of aflatoxins: an update. Comput Biol Bioinform, 8, 62-71.
29. Khattak, A. K., Syeda, M. H., & Shahzad, S. M. (2020). General overview of phytochemistry and pharmacological potential of Rheum palmatum (Chinese rhubarb). Innovare Journal of Ayurvedic Sciences, 8 (6), 1-5.
30. Latif, M. J., Hassan, S. M., Mughal, S. S., Aslam, A., Munir, M., Shabbir, N.,... & Perveiz, S. (2020). Therapeutic potential of Azadirachta indica (neem) and their active phytoconstituents against diseases prevention. J. Chem Cheml Sci., 10 (3), 98-110.
31. Khalid, Z., Hassan, S., Shahzad, S., & Khurram, H. (2021). A review on biological attributes of Momordica charantia. Adv Biosci Bioeng, 9 (1), 8-12.
32. Hafeez, M., Hassan, S. M., Mughal, S. S., Munir, M., & Khan, M. K. (2020). Antioxidant, Antimicrobial and Cytotoxic Potential of Abelmoschus esculentus. Chemical and Biomolecular Engineering, 5 (4), 69.
33. Afzal, N., Hassan, S. M., Mughal, S. S., Pando, A., & Rafiq, A. (2022). Control of Aflatoxins in Poultry Feed by Using Yeast. American Journal of Chemical and Biochemical Engineering, 6 (1), 21-26.
34. Shabbir, N., Hassan, S. M., Mughal, S. S., Pando, A., & Rafiq, A. (2022). Eletteria cardamomum and Greenly Synthesized MgO NPs: A Detailed Review of Their Properties and Applications. Engineering Science, 7 (1), 15-22.
35. Mubeen, N., Hassan, S. M., & Mughal, S. S. (2020). A Biological Approach to Control Aflatoxins by Moringa Oleifera. International Journal of Bioorganic Chemistry, 5 (2), 21.
36. Mubeen, N., Hassan, S. M., Mughal, S. S., Hassan, S. K., Ibrahim, A., Hassan, H., & Mushtaq, M. (2020). Vitality and Implication of Natural Products from Moringa oleifera: An Eco-Friendly Approach. Computational Biology and Bioinformatics, 8 (2), 72.
37. Aslam, A., Hassan, S. M., Mughal, S. S., Hassan, S. K., Ibrahim, A., Hassan, H.,... & Shafiq, S. (2020). Comprehensive Review of Structural Components of Salvia hispanica & Its Biological Applications. International Journal of Biochemistry, Biophysics & Molecular Biology, 5 (1), 1.
38. Mughal, S. S., & Hassan, S. M. (2022). Comparative Study of AgO Nanoparticles Synthesize Via Biological, Chemical and Physical Methods: A Review. American Journal of Materials Synthesis and Processing, 7 (2), 15-28.
39. Rafique, S., Hassan, S. M., Mughal, S. S., & Afzal, N. (2020). Asma Shafi 2, Sehrish Kamran 3 Department of Chemistry, Lahore Garrison University, Lahore, Punjab, Pakistan 2 Deparment of polymer, Punjab University Lahore, Pakistan 3 Department of Allied sciences, FMH College of medicine and dentistry. GSJ, 8 (9).
40. Anam Khushi, Syeda Mona Hassan, Shahzad Sharif Mughal, Antimicrobial and Structural Investigation of Green Synthesized ZnO Nanostructures from Bougainvillea glabra Leaves Extract, Biochemistry and Molecular Biology. Volume 7, Issue 3, September 2022, pp. 61-69. doi: 10.11648/j.bmb.20220703.12.
41. Abbas, F., Tahir, M. U., Farman, M., Mumtaz, M., Aslam, M. R., Mughal, S. S.,... & Khan, A. R. Synthesis and Characterization of Silver Nanoparticles Against Two Stored Commodity Insect Pests.
42. Aslam, A., Hassan, S. M., Mughal, S. S., Perveiz, S., Mushtaq, M., Munir, M.,... & Ayub, A. R. Investigation of Biological Activity of Salvia hispanica.
44. ul Mustafa, Z., ullah Khan, A., Mudasar, A. S., & Mughal, S. S. Edge Functionalization of Phosphorene with different Chemical Functional Groups.
45. Muneer, M., Mughal, S. S., Pervez, S., Mushtaq, M., Shabbir, N., Aslam, A.,... & Abbas, F. DIAGNOSIS AND TREATMENT OF DISEASES BY USING METALLIC NANOPARTICLES-A REVIEW.
46. Mughal, S., Abbas, F., Tahir, M., Ayub, A., Javed, H., Mamtaz, M., & Iram, H. (2019). Role of Silver Nanoparticles in Colorimetric Detection of Biomolecules. doi: 10.7537/marsbnj050419.04.
47. Perveiz, S., Hassan, S. M., Mughal, S. S., Pando, A., Rafiq, A., & Shabbir, N. Structural, Morphological and Biotoxicity Studies of Biosynthesized CaO Nanoparticles Via Cuminum Cyminum.
49. Perveiz, S., Hassan, S. M., Mughal, S. S., Ullah, H., Shabbir, N., Munir, M.,... & Farman, M. A Review on Heavy metal contamination in water and the Strategies for the Reduction of Pollution Load of Commercial and Industrial Areas of Pakistan.
50. Hafeez, M., Hassan, S. M., Mughal, S. S., & Mushtaq, M. Evaluation of Biological Characteristics of Abelmoschus esculentus.
51. Hassan, S. M., Mubeen, N., Hassan, S. K., Ibrahim, A., Hassan, H., Mughal, S. S.,... & Haider, G. MORINGA Oleifera, A MULTIFUNCTIONAL PLANT: A REVIEW STUDY.