@article{10.11648/j.cmr.20251403.14,
  author = {Anna-Maria Borissova and Boyana Trifonova and Lilia Dakovska and Mircho Vukov},
  title = {Characteristics and Dynamics of Thyroid Dysfunction in the Bulgarian Population - Screening 2024
},
  journal = {Clinical Medicine Research},
  volume = {14},
  number = {3},
  pages = {65-79},
  doi = {10.11648/j.cmr.20251403.14},
  url = {https://doi.org/10.11648/j.cmr.20251403.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20251403.14},
  abstract = {In 1994 universal iodization of salt was introduced on the whole Bulgarian territory. In 2005, аn international expert group gave the country credit for solving the problem of iodine deficiency. The last screening of pregnant Bulgarian women in 2019 confirmed the presence of iodine sufficiency among the population. The current study aimed at updating the data on the prevalence of thyroid dysfunction (hypothyroidism and hyperthyroidism) in the country under conditions of iodine sufficiency in the Bulgarian population. The last population screening was conducted 12 years ago, allowing us to make a comparison with the current one in 2024, as both screenings were carried out under the conditions of systematic and continuous universal iodization of salt across the entire territory of Bulgaria. Material and Methods: 936 subjects were distributed into three age groups: 20-44 years - 342 (36.5%), 45-59 years - 301 (32.2%) and 60-79 years - 293 (31.3%). TSH (ECLIA-sandwich method), FT4 (competitive ECLIA method), TPOAb (ECLIA-method of the Cobas e601 analyzer) were examined. Thyroid dysfunction, which includes subclinical and clinical forms, was analysed regarding the frequency of each type and form in the studied population, as well as its distribution according to gender and among the three age groups. The data gathered in 2012 and 2024 were compared. Results: Hypothyroidism is the dominant disorder - 14.4% (135/936), while hyperthyroidism is 1.81% (17/936), p  0.01, while the relative share of newly diagnosed cases during screening has a significant drop - from 55.49% (91/164) to 36.84% (56/152) - p Conclusion: These favorable trends in the reduction of undiagnosed cases of thyroid dysfunction are the result of increased diagnosis of thyroid pathology, ongoing regular screening campaigns, and raised awareness among the population, which is proof of the medical community beneficial work in the country.
},
 year = {2025}
}

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TY  - JOUR
T1  - Characteristics and Dynamics of Thyroid Dysfunction in the Bulgarian Population - Screening 2024

AU  - Anna-Maria Borissova
AU  - Boyana Trifonova
AU  - Lilia Dakovska
AU  - Mircho Vukov
Y1  - 2025/06/12
PY  - 2025
N1  - https://doi.org/10.11648/j.cmr.20251403.14
DO  - 10.11648/j.cmr.20251403.14
T2  - Clinical Medicine Research
JF  - Clinical Medicine Research
JO  - Clinical Medicine Research
SP  - 65
EP  - 79
PB  - Science Publishing Group
SN  - 2326-9057
UR  - https://doi.org/10.11648/j.cmr.20251403.14
AB  - In 1994 universal iodization of salt was introduced on the whole Bulgarian territory. In 2005, аn international expert group gave the country credit for solving the problem of iodine deficiency. The last screening of pregnant Bulgarian women in 2019 confirmed the presence of iodine sufficiency among the population. The current study aimed at updating the data on the prevalence of thyroid dysfunction (hypothyroidism and hyperthyroidism) in the country under conditions of iodine sufficiency in the Bulgarian population. The last population screening was conducted 12 years ago, allowing us to make a comparison with the current one in 2024, as both screenings were carried out under the conditions of systematic and continuous universal iodization of salt across the entire territory of Bulgaria. Material and Methods: 936 subjects were distributed into three age groups: 20-44 years - 342 (36.5%), 45-59 years - 301 (32.2%) and 60-79 years - 293 (31.3%). TSH (ECLIA-sandwich method), FT4 (competitive ECLIA method), TPOAb (ECLIA-method of the Cobas e601 analyzer) were examined. Thyroid dysfunction, which includes subclinical and clinical forms, was analysed regarding the frequency of each type and form in the studied population, as well as its distribution according to gender and among the three age groups. The data gathered in 2012 and 2024 were compared. Results: Hypothyroidism is the dominant disorder - 14.4% (135/936), while hyperthyroidism is 1.81% (17/936), p  0.01, while the relative share of newly diagnosed cases during screening has a significant drop - from 55.49% (91/164) to 36.84% (56/152) - p Conclusion: These favorable trends in the reduction of undiagnosed cases of thyroid dysfunction are the result of increased diagnosis of thyroid pathology, ongoing regular screening campaigns, and raised awareness among the population, which is proof of the medical community beneficial work in the country.

VL  - 14
IS  - 3
ER  - 

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