Journal of Cancer Treatment and Research

Case Report | | Peer-Reviewed |

Male’s Primary Breast Lymphoma: Rare Entity of Breast Malignancy, Wad Madani Teaching Hospital, Gezira State, Sudan, August 2023

Received: 27 December 2023    Accepted: 6 January 2024    Published: 27 February 2024
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Abstract

Background: Primary breast lymphoma is a malignant lymphoma primarily involving breast in absence of previously detected lymphoma localizations. Method: A male of forty years old admitted to Department of Surgery; Wad Madani Teaching Hospital; Gezira State; Sudan; complaining of left breast lump for three months. Condition observed as a painful swelling in left breast, increasing gradually in size, associated with continuous high-grade fever, no rigors and relieved by analgesia, no nipple discharges. Had significant weight loss, anorexia, fatigability, back pain, dry cough with no hemoptysis, no history of headache, and no past or family history of similar condition. Examination: patient looks ill, pale, and not jaundiced. Breast examination: Left breast was larger than right one. Left breast: no nipple destruction, nipple was directed downward medially, no skin changes or dimpling, and no ulceration. There was a mass in left upper outer quadrant, measuring 6*7 cm, smooth surface, hard in consistency with well-defined edges, and attached to muscles but not to skin. No palpable axillary lymph nodes. Right breast was normal. Chest and abdominal examination were unremarkable. Investigations: Fine needle aspiration cytology showed poorly differentiated carcinoma. Incisional biopsy revealed: high grade Non-Hodgkins Lymphomas (Diffuse Large B Cell Lymphoma). He was referred to oncological department for neoadjuvant chemoradiotherapy. Conclusion and Recommendation: Primarily breast lymphoma is extremely rare among male, showing features mimicking breast carcinoma. Incisional biopsy was recommended for investigation of breast lump especially among males.

DOI 10.11648/j.jctr.20241201.13
Published in Journal of Cancer Treatment and Research (Volume 12, Issue 1, March 2024)
Page(s) 18-20
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Primary Breast Lymphoma Among Male, Wad Madani Teaching Hospital, Gezira State, Sudan

References
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[2] Orlandi A, et al, Diagnosis and management of breast lymphoma: a single-institution retrospective analysis, Transl Cancer Res, 2018, 7(3), pp: (S272-S280).
[3] Joks M, Myśliwiec K, Lewandowski K, Primary breast lymphoma – a review of the literature and report of three cases, Arch Med Sci 2011, 7(1), PP: (27-33).
[4] Sonkaria M, et al, Primary breast lymphoma: A case series and review, Indian J Case Reports, 2020, 6(6), pp: (288-291).
[5] Guo M, Liu J, Gilmore R, Tian G G, Primary breast diffuse large B cell lymphoma, BMJ Case Rep 2022, 15: e250478. http://doi.org/10.1136/bcr-2022-250478
[6] Mohamed K. E. H, Ali R. A. E, Primary breast lymphoma: a case report and review of the literature, Clinics and Practice 2017, 7(939), PP: (99-100).
[7] Cheah C Y, Campbell B A, Seymour J F, et al, Primary breast lymphoma, Cancer Treat Rev 2014, http://dx.doi.org/10.1016/j.ctrv.2014.05.010
[8] Taheri H, Hmila A, Saadi H, Mimouni A, Primary breast lymphoma: a case report, Int J Reprod Contracept Obstet Gynecol. 2020, 9(5), pp: (2187-2190).
[9] Corobea A B, et al, Diffuse Large B Cell Lymphoma in a Male Breast – A Rare Case Report, Chirurgia 2017, 112, pp: (477-481).
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  • APA Style

    Elmukashfi, O. T. A., Elsheikh, T. A. E., Alshaikh, A. A., Dafalla, A. A. E., Omer, W. O. E., et al. (2024). Male’s Primary Breast Lymphoma: Rare Entity of Breast Malignancy, Wad Madani Teaching Hospital, Gezira State, Sudan, August 2023. Journal of Cancer Treatment and Research, 12(1), 18-20. https://doi.org/10.11648/j.jctr.20241201.13

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    ACS Style

    Elmukashfi, O. T. A.; Elsheikh, T. A. E.; Alshaikh, A. A.; Dafalla, A. A. E.; Omer, W. O. E., et al. Male’s Primary Breast Lymphoma: Rare Entity of Breast Malignancy, Wad Madani Teaching Hospital, Gezira State, Sudan, August 2023. J. Cancer Treat. Res. 2024, 12(1), 18-20. doi: 10.11648/j.jctr.20241201.13

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    AMA Style

    Elmukashfi OTA, Elsheikh TAE, Alshaikh AA, Dafalla AAE, Omer WOE, et al. Male’s Primary Breast Lymphoma: Rare Entity of Breast Malignancy, Wad Madani Teaching Hospital, Gezira State, Sudan, August 2023. J Cancer Treat Res. 2024;12(1):18-20. doi: 10.11648/j.jctr.20241201.13

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  • @article{10.11648/j.jctr.20241201.13,
      author = {Omer Taha Ahmed Elmukashfi and Taha Ahmed Elmukashfi Elsheikh and Ahmad Alamin Alshaikh and Afnan Abdelrahman Elsiddig Dafalla and Wala Osman Eltieb Omer and Asma Mohammed Warrag Omer and Osman Elfatih Elheber Omer and Eman Ali Ahmed Mohamed and Osman Merghani Osman Mahmoud},
      title = {Male’s Primary Breast Lymphoma: Rare Entity of Breast Malignancy, Wad Madani Teaching Hospital, Gezira State, Sudan, August 2023},
      journal = {Journal of Cancer Treatment and Research},
      volume = {12},
      number = {1},
      pages = {18-20},
      doi = {10.11648/j.jctr.20241201.13},
      url = {https://doi.org/10.11648/j.jctr.20241201.13},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jctr.20241201.13},
      abstract = {Background: Primary breast lymphoma is a malignant lymphoma primarily involving breast in absence of previously detected lymphoma localizations. Method: A male of forty years old admitted to Department of Surgery; Wad Madani Teaching Hospital; Gezira State; Sudan; complaining of left breast lump for three months. Condition observed as a painful swelling in left breast, increasing gradually in size, associated with continuous high-grade fever, no rigors and relieved by analgesia, no nipple discharges. Had significant weight loss, anorexia, fatigability, back pain, dry cough with no hemoptysis, no history of headache, and no past or family history of similar condition. Examination: patient looks ill, pale, and not jaundiced. Breast examination: Left breast was larger than right one. Left breast: no nipple destruction, nipple was directed downward medially, no skin changes or dimpling, and no ulceration. There was a mass in left upper outer quadrant, measuring 6*7 cm, smooth surface, hard in consistency with well-defined edges, and attached to muscles but not to skin. No palpable axillary lymph nodes. Right breast was normal. Chest and abdominal examination were unremarkable. Investigations: Fine needle aspiration cytology showed poorly differentiated carcinoma. Incisional biopsy revealed: high grade Non-Hodgkins Lymphomas (Diffuse Large B Cell Lymphoma). He was referred to oncological department for neoadjuvant chemoradiotherapy. Conclusion and Recommendation: Primarily breast lymphoma is extremely rare among male, showing features mimicking breast carcinoma. Incisional biopsy was recommended for investigation of breast lump especially among males.
    },
     year = {2024}
    }
    

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  • TY  - JOUR
    T1  - Male’s Primary Breast Lymphoma: Rare Entity of Breast Malignancy, Wad Madani Teaching Hospital, Gezira State, Sudan, August 2023
    AU  - Omer Taha Ahmed Elmukashfi
    AU  - Taha Ahmed Elmukashfi Elsheikh
    AU  - Ahmad Alamin Alshaikh
    AU  - Afnan Abdelrahman Elsiddig Dafalla
    AU  - Wala Osman Eltieb Omer
    AU  - Asma Mohammed Warrag Omer
    AU  - Osman Elfatih Elheber Omer
    AU  - Eman Ali Ahmed Mohamed
    AU  - Osman Merghani Osman Mahmoud
    Y1  - 2024/02/27
    PY  - 2024
    N1  - https://doi.org/10.11648/j.jctr.20241201.13
    DO  - 10.11648/j.jctr.20241201.13
    T2  - Journal of Cancer Treatment and Research
    JF  - Journal of Cancer Treatment and Research
    JO  - Journal of Cancer Treatment and Research
    SP  - 18
    EP  - 20
    PB  - Science Publishing Group
    SN  - 2376-7790
    UR  - https://doi.org/10.11648/j.jctr.20241201.13
    AB  - Background: Primary breast lymphoma is a malignant lymphoma primarily involving breast in absence of previously detected lymphoma localizations. Method: A male of forty years old admitted to Department of Surgery; Wad Madani Teaching Hospital; Gezira State; Sudan; complaining of left breast lump for three months. Condition observed as a painful swelling in left breast, increasing gradually in size, associated with continuous high-grade fever, no rigors and relieved by analgesia, no nipple discharges. Had significant weight loss, anorexia, fatigability, back pain, dry cough with no hemoptysis, no history of headache, and no past or family history of similar condition. Examination: patient looks ill, pale, and not jaundiced. Breast examination: Left breast was larger than right one. Left breast: no nipple destruction, nipple was directed downward medially, no skin changes or dimpling, and no ulceration. There was a mass in left upper outer quadrant, measuring 6*7 cm, smooth surface, hard in consistency with well-defined edges, and attached to muscles but not to skin. No palpable axillary lymph nodes. Right breast was normal. Chest and abdominal examination were unremarkable. Investigations: Fine needle aspiration cytology showed poorly differentiated carcinoma. Incisional biopsy revealed: high grade Non-Hodgkins Lymphomas (Diffuse Large B Cell Lymphoma). He was referred to oncological department for neoadjuvant chemoradiotherapy. Conclusion and Recommendation: Primarily breast lymphoma is extremely rare among male, showing features mimicking breast carcinoma. Incisional biopsy was recommended for investigation of breast lump especially among males.
    
    VL  - 12
    IS  - 1
    ER  - 

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Author Information
  • General Surgery Council, Sudan Medical Specialization Board, Khartoum, Sudan

  • Department of Community Medicine, Faculty of Medicine, University of Khartoum, Khartoum, Sudan

  • Department of General Surgery, Faculty of Medicine, University of Gezira, Wad Madani, Sudan

  • Department of Training, Federal Ministry of Health, Khartoum, Sudan

  • General Surgery Council, Sudan Medical Specialization Board, Khartoum, Sudan

  • National Cancer Institute (NCI), University of Gezira, Wad Madani, Sudan

  • General Surgery Council, Sudan Medical Specialization Board, Khartoum, Sudan

  • Department of General Surgery, Faculty of Medicine, University of Gezira, Wad Madani, Sudan

  • Department of General Surgery, Fajer Medical College, Khartoum, Sudan

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