The plant Bombax buonopozense is a large tropical tree that grows up to 40 meters. Scattered in the dry and rain forest, widely distributed in African countries such as Ghana, Nigeria, Sierra Leone, Uganda, Liberia, Gabon, and different parts are used for different ailments. The study targets phytochemical screening, antimicrobial and anti-inflammatory activities of the plant leaf to substantiate some of its ethno-medicinal uses. The phytochemical composition was evaluated using standard procedures and the antimicrobial activity of the extracts using the agar diffusion method on the following clinical isolates: (Staphylococcus aureus (ATCC 29213), Streptococcus faecials, Bacillus subtilis (ATCC 8263), Escherichia coli (ATCC 25922), Salmonella tiphi, Pseudomonas aeruginosa (ATCC 27853), Candida albican (ATCC 90029), Aspergillus niger and Phytophera megakarya. Anti-inflammatory activity was also evaluated using carrageenan-induced oedema of the rat paw. Phytochemical screening revealed the presence of saponins, tannins, flavonoids, carbohydrates, terpenoids, anthraquinone, steroids, reducing sugar, phenols, alkaloids, and phlobatannins. The leaf extract had strong activity on Strep. faecalis, E. coli, P. Aeruginosa and moderate to little activity on the rest of test organisms. The leaf extract suppressed the onset of inflammatory but did not sustain it till 3rd h compared to reference drug (Diclofenac). The findings indicate leaf extract contain some bioactive compounds which may be used for possible treatment of microbial infections and oxidative stress related diseases which justify its ethno-medicinal uses.
| Published in | Journal of Diseases and Medicinal Plants (Volume 8, Issue 3) |
| DOI | 10.11648/j.jdmp.20220803.13 |
| Page(s) | 61-65 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
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Copyright © The Author(s), 2022. Published by Science Publishing Group |
Bombax buonopozense, Phytochemical, Antimicrobial, Anti-inflammatory
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APA Style
Moruf Ademola Yusuf-Babatunde, Lateef Saka Kasim, Thomas Oyebode Idowu. (2022). Phytochemical Screening, Antimicrobial and Anti-inflammatory Activities of Ethanolic Extracts of the Leaf of Bombax buonopozense P. Beauv. (Bombacaceae). Journal of Diseases and Medicinal Plants, 8(3), 61-65. https://doi.org/10.11648/j.jdmp.20220803.13
ACS Style
Moruf Ademola Yusuf-Babatunde; Lateef Saka Kasim; Thomas Oyebode Idowu. Phytochemical Screening, Antimicrobial and Anti-inflammatory Activities of Ethanolic Extracts of the Leaf of Bombax buonopozense P. Beauv. (Bombacaceae). J. Dis. Med. Plants 2022, 8(3), 61-65. doi: 10.11648/j.jdmp.20220803.13
AMA Style
Moruf Ademola Yusuf-Babatunde, Lateef Saka Kasim, Thomas Oyebode Idowu. Phytochemical Screening, Antimicrobial and Anti-inflammatory Activities of Ethanolic Extracts of the Leaf of Bombax buonopozense P. Beauv. (Bombacaceae). J Dis Med Plants. 2022;8(3):61-65. doi: 10.11648/j.jdmp.20220803.13
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Download@article{10.11648/j.jdmp.20220803.13,
author = {Moruf Ademola Yusuf-Babatunde and Lateef Saka Kasim and Thomas Oyebode Idowu},
title = {Phytochemical Screening, Antimicrobial and Anti-inflammatory Activities of Ethanolic Extracts of the Leaf of Bombax buonopozense P. Beauv. (Bombacaceae)},
journal = {Journal of Diseases and Medicinal Plants},
volume = {8},
number = {3},
pages = {61-65},
doi = {10.11648/j.jdmp.20220803.13},
url = {https://doi.org/10.11648/j.jdmp.20220803.13},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jdmp.20220803.13},
abstract = {The plant Bombax buonopozense is a large tropical tree that grows up to 40 meters. Scattered in the dry and rain forest, widely distributed in African countries such as Ghana, Nigeria, Sierra Leone, Uganda, Liberia, Gabon, and different parts are used for different ailments. The study targets phytochemical screening, antimicrobial and anti-inflammatory activities of the plant leaf to substantiate some of its ethno-medicinal uses. The phytochemical composition was evaluated using standard procedures and the antimicrobial activity of the extracts using the agar diffusion method on the following clinical isolates: (Staphylococcus aureus (ATCC 29213), Streptococcus faecials, Bacillus subtilis (ATCC 8263), Escherichia coli (ATCC 25922), Salmonella tiphi, Pseudomonas aeruginosa (ATCC 27853), Candida albican (ATCC 90029), Aspergillus niger and Phytophera megakarya. Anti-inflammatory activity was also evaluated using carrageenan-induced oedema of the rat paw. Phytochemical screening revealed the presence of saponins, tannins, flavonoids, carbohydrates, terpenoids, anthraquinone, steroids, reducing sugar, phenols, alkaloids, and phlobatannins. The leaf extract had strong activity on Strep. faecalis, E. coli, P. Aeruginosa and moderate to little activity on the rest of test organisms. The leaf extract suppressed the onset of inflammatory but did not sustain it till 3rd h compared to reference drug (Diclofenac). The findings indicate leaf extract contain some bioactive compounds which may be used for possible treatment of microbial infections and oxidative stress related diseases which justify its ethno-medicinal uses.},
year = {2022}
}
TY - JOUR T1 - Phytochemical Screening, Antimicrobial and Anti-inflammatory Activities of Ethanolic Extracts of the Leaf of Bombax buonopozense P. Beauv. (Bombacaceae) AU - Moruf Ademola Yusuf-Babatunde AU - Lateef Saka Kasim AU - Thomas Oyebode Idowu Y1 - 2022/09/29 PY - 2022 N1 - https://doi.org/10.11648/j.jdmp.20220803.13 DO - 10.11648/j.jdmp.20220803.13 T2 - Journal of Diseases and Medicinal Plants JF - Journal of Diseases and Medicinal Plants JO - Journal of Diseases and Medicinal Plants SP - 61 EP - 65 PB - Science Publishing Group SN - 2469-8210 UR - https://doi.org/10.11648/j.jdmp.20220803.13 AB - The plant Bombax buonopozense is a large tropical tree that grows up to 40 meters. Scattered in the dry and rain forest, widely distributed in African countries such as Ghana, Nigeria, Sierra Leone, Uganda, Liberia, Gabon, and different parts are used for different ailments. The study targets phytochemical screening, antimicrobial and anti-inflammatory activities of the plant leaf to substantiate some of its ethno-medicinal uses. The phytochemical composition was evaluated using standard procedures and the antimicrobial activity of the extracts using the agar diffusion method on the following clinical isolates: (Staphylococcus aureus (ATCC 29213), Streptococcus faecials, Bacillus subtilis (ATCC 8263), Escherichia coli (ATCC 25922), Salmonella tiphi, Pseudomonas aeruginosa (ATCC 27853), Candida albican (ATCC 90029), Aspergillus niger and Phytophera megakarya. Anti-inflammatory activity was also evaluated using carrageenan-induced oedema of the rat paw. Phytochemical screening revealed the presence of saponins, tannins, flavonoids, carbohydrates, terpenoids, anthraquinone, steroids, reducing sugar, phenols, alkaloids, and phlobatannins. The leaf extract had strong activity on Strep. faecalis, E. coli, P. Aeruginosa and moderate to little activity on the rest of test organisms. The leaf extract suppressed the onset of inflammatory but did not sustain it till 3rd h compared to reference drug (Diclofenac). The findings indicate leaf extract contain some bioactive compounds which may be used for possible treatment of microbial infections and oxidative stress related diseases which justify its ethno-medicinal uses. VL - 8 IS - 3 ER -
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