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Giant Vulvar Lipoma: A Case Report and Literature Review

Received: 31 October 2022    Accepted: 23 November 2022    Published: 8 December 2022
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Abstract

Lipoma is the common benign soft tissue tumors. However, to date, few reports of vulvar lipomas have been reported. This article reports a rarer and relatively large type of vulvar lipoma. Below is the case of a 32-year-old woman who has a huge right vulvar lump. She was admitted to the hospital because she touched a growing lump on the right side of her vulva. Self-reported no special discomfort, the mass is non-tender, no activity, slow-growing, and the size is about 11*6*5cm. She also reported discomfort when walking for nearly two months, accompanied by friction and a feeling of foreign bodies. In gynaecological clinics, ultrasonography suggests a possible diagnosis of lipoma, and further CT (computed tomography) and MRI (magnetic resonance imaging) studies show the diagnosis of lipoma. Combined with the patient's history and ancillary examination, surgery is currently indicated and the patient strongly requests surgery. Therefore, after improving the relevant blood and urine routine, coagulation function, liver and kidney function and other auxiliary examinations after admission, the patient had no obvious contraindications to surgery, and under general anesthesia, the author's team reconstructed the vulva, restored the beauty of the vulva, and completely removed the mass. Postoperative pathological findings suggest a diagnosis of lipoma. Since vulvar lipomas are uncommon, especially in young women. And there is a greater possibility of being misdiagnosed. Therefore, it is also important to identify this benign vulvar mass in daily management. Based on this, the author's team reported a relatively rare case of giant vulvar lipoma.

Published in Journal of Gynecology and Obstetrics (Volume 10, Issue 6)
DOI 10.11648/j.jgo.20221006.13
Page(s) 253-256
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Lipoma, Vulvar, Vulvar Diseases, Benign Tumour, Giant Lipoma

References
[1] Elakhiri M, Darouassi Y, Oukabli M, Jahidi A, Benariba F. Prise en charge dun lipoma cervical géant: à propos dun cas et revue de la littérature [Management of a giant cervical lipoma: case report and literature review]. Pan Afr Med J. 2021 Jun 3; 39: 100. French. doi: 10.11604/pamj.2021.39.100.12727. PMID: 34466202; PMCID: PMC8379405.
[2] Ramírez-Macías MA, Álvarez-García B, Rayo JAM, Garza IR, Piñeiro-Díaz J, López-Valdés JC. Giant vulvar lipoma. Cir Cir. 2021; 89 (5): 694-695. English. doi: 10.24875/CIRU.20000311. PMID: 34665172.
[3] Sukgen G. A Case Report: The Third-largest Case in the Literature of a Vulvar Lipoma. Gynecol Minim Invasive Ther. 2020 Oct 15; 9 (4): 234-236. doi: 10.4103/GMIT.GMIT_45_19. PMID: 33312869; PMCID: PMC7713658.
[4] Reda A, Gomaa I. Vulvar Lipoma: A Case Report. Rev Bras Ginecol Obstet. 2018 Oct; 40 (10): 647-649. doi: 10.1055/s-0038-1670642. Epub 2018 Oct 23. PMID: 30352464.
[5] Moshref LH, Malaekah H. A Large Lipoma of the Labia Majora. Cureus. 2021 Nov 30; 13 (11): e20066. doi: 10.7759/cureus.20066. PMID: 35003940; PMCID: PMC8723716.
[6] Charifa A, Azmat CE, Badri T: Lipoma Pathology. StatPearls Publishing, Treasure Island, FL; 2021.
[7] Dekonda N, Koremilli R, Wattamwar A, et al. Vulvar lipoma - a case series. IOSR-JDMS. 2019, 18: 14-16. 10.9790/0853-1809121416
[8] Yang DM, Kim HC, Kim SW, Won KY: Groin abnormalities: ultrasonographic and clinical findings. Ultrasonography. 2020, 39: 166-77. 10.14366/usg.19041
[9] Altal OF, Rawashdeh S, Al Sharie S, Al Zu'bi YO, Al Sharie AH, Daoud MN, Alkhawaldeh KM. Surgical excision of giant vulvar angiofibroma: A case report and a review of literature. Medicine (Baltimore). 2022 Sep 9; 101 (36): e30125. doi: 10.1097/MD.0000000000030125. PMID: 36086676.
[10] Coban YK, Uzel M, Gumus N. Lipoma due to chronic intermittent compression as an occupational disease. Ann Plast Surg 2006; 57 (03): 275–278. Doi: 10.1097/01.01.sap.0000223205.88824.39
[11] Bianchini L, Birtwisle L, Saâda E, et al. Identifification of PPAP2B as a novel recurrent translocation partner gene of HMGA2 in lipomas. Genes Chromosomes Cancer 2013; 52 (06): 580–590. Doi: 10.1002/ gcc.22055
[12] Heller DS. Benign Tumors and Tumor-like Lesions of the Vulva. Clin Obstet Gynecol. 2015 Sep; 58 (3): 526-35. doi: 10.1097/GRF.0000000000000133. PMID: 26125957.
[13] Sanchez MR, Golomb FM, Moy JA, Potozkin JR. Giant lipoma: case report and review of the literature. J Am Acad Dermatol. 1993 Feb; 28 (2 Pt 1): 266-8. PubMed| Google Scholar.
[14] Aust MC, Spies M, Kall S, Gohritz A, Boorboor P, Kolokythas P, Vogt PM. Lipomas after blunt soft tissue trauma: are they real? Analysis of 31 cases. Br J Dermatol. 2007 Jul; 157 (1): 92-9. doi: 10.1111/j.1365-2133.2007.07970.x. Epub 2007 Jun 6. PMID: 17553055
[15] Lee JH, Chung SM. Large vulvar lipoma in an adolescent: a case report. J Korean Med Sci. 2008 Aug; 23 (4): 744-6. doi: 10.3346/jkms.2008.23.4.744. PMID: 18756071; PMCID: PMC2526395. Coban YK, Uzel M, Gumus N. Lipoma due to chronic intermittent compression as an occupational disease. Ann Plast Surg. 2006 Sep; 57 (3): 275-8. doi: 10.1097/01.sap.0000223205.88824.39. PMID: 16929194.
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[17] Jourjon, R., et al., Angiolipoma of the labia majora: MR imaging findings with histopathological correlation. Clin Imaging, 2013. 37 (5): p. 965-8.
[18] Sherer DM, Gorelick C, Wagreich A, Lee YC, Serur E, Zigalo A, Abulafia O. Sonographic findings of a large vulvar lipoma. Ultrasound Obstet Gynecol. 2007 Oct; 30 (5): 786-7. doi: 10.1002/uog.5130. PMID: 17763338.
Cite This Article
  • APA Style

    Mengru Zhao, Ying Cao, Yao Chen, Yun Yang, Mengyue Chen, et al. (2022). Giant Vulvar Lipoma: A Case Report and Literature Review. Journal of Gynecology and Obstetrics, 10(6), 253-256. https://doi.org/10.11648/j.jgo.20221006.13

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    ACS Style

    Mengru Zhao; Ying Cao; Yao Chen; Yun Yang; Mengyue Chen, et al. Giant Vulvar Lipoma: A Case Report and Literature Review. J. Gynecol. Obstet. 2022, 10(6), 253-256. doi: 10.11648/j.jgo.20221006.13

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    AMA Style

    Mengru Zhao, Ying Cao, Yao Chen, Yun Yang, Mengyue Chen, et al. Giant Vulvar Lipoma: A Case Report and Literature Review. J Gynecol Obstet. 2022;10(6):253-256. doi: 10.11648/j.jgo.20221006.13

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  • @article{10.11648/j.jgo.20221006.13,
      author = {Mengru Zhao and Ying Cao and Yao Chen and Yun Yang and Mengyue Chen and Huimin Tang and Junling Liu and Weiwei Wei and Tingwei Xing and Ruxia Shi and Bairong Xia and Jiming Chen},
      title = {Giant Vulvar Lipoma: A Case Report and Literature Review},
      journal = {Journal of Gynecology and Obstetrics},
      volume = {10},
      number = {6},
      pages = {253-256},
      doi = {10.11648/j.jgo.20221006.13},
      url = {https://doi.org/10.11648/j.jgo.20221006.13},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jgo.20221006.13},
      abstract = {Lipoma is the common benign soft tissue tumors. However, to date, few reports of vulvar lipomas have been reported. This article reports a rarer and relatively large type of vulvar lipoma. Below is the case of a 32-year-old woman who has a huge right vulvar lump. She was admitted to the hospital because she touched a growing lump on the right side of her vulva. Self-reported no special discomfort, the mass is non-tender, no activity, slow-growing, and the size is about 11*6*5cm. She also reported discomfort when walking for nearly two months, accompanied by friction and a feeling of foreign bodies. In gynaecological clinics, ultrasonography suggests a possible diagnosis of lipoma, and further CT (computed tomography) and MRI (magnetic resonance imaging) studies show the diagnosis of lipoma. Combined with the patient's history and ancillary examination, surgery is currently indicated and the patient strongly requests surgery. Therefore, after improving the relevant blood and urine routine, coagulation function, liver and kidney function and other auxiliary examinations after admission, the patient had no obvious contraindications to surgery, and under general anesthesia, the author's team reconstructed the vulva, restored the beauty of the vulva, and completely removed the mass. Postoperative pathological findings suggest a diagnosis of lipoma. Since vulvar lipomas are uncommon, especially in young women. And there is a greater possibility of being misdiagnosed. Therefore, it is also important to identify this benign vulvar mass in daily management. Based on this, the author's team reported a relatively rare case of giant vulvar lipoma.},
     year = {2022}
    }
    

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    T1  - Giant Vulvar Lipoma: A Case Report and Literature Review
    AU  - Mengru Zhao
    AU  - Ying Cao
    AU  - Yao Chen
    AU  - Yun Yang
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    AU  - Weiwei Wei
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    AU  - Bairong Xia
    AU  - Jiming Chen
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    UR  - https://doi.org/10.11648/j.jgo.20221006.13
    AB  - Lipoma is the common benign soft tissue tumors. However, to date, few reports of vulvar lipomas have been reported. This article reports a rarer and relatively large type of vulvar lipoma. Below is the case of a 32-year-old woman who has a huge right vulvar lump. She was admitted to the hospital because she touched a growing lump on the right side of her vulva. Self-reported no special discomfort, the mass is non-tender, no activity, slow-growing, and the size is about 11*6*5cm. She also reported discomfort when walking for nearly two months, accompanied by friction and a feeling of foreign bodies. In gynaecological clinics, ultrasonography suggests a possible diagnosis of lipoma, and further CT (computed tomography) and MRI (magnetic resonance imaging) studies show the diagnosis of lipoma. Combined with the patient's history and ancillary examination, surgery is currently indicated and the patient strongly requests surgery. Therefore, after improving the relevant blood and urine routine, coagulation function, liver and kidney function and other auxiliary examinations after admission, the patient had no obvious contraindications to surgery, and under general anesthesia, the author's team reconstructed the vulva, restored the beauty of the vulva, and completely removed the mass. Postoperative pathological findings suggest a diagnosis of lipoma. Since vulvar lipomas are uncommon, especially in young women. And there is a greater possibility of being misdiagnosed. Therefore, it is also important to identify this benign vulvar mass in daily management. Based on this, the author's team reported a relatively rare case of giant vulvar lipoma.
    VL  - 10
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Author Information
  • Graduate School, Dalian Medical University, Dalian, PR China

  • Department of Gynecology, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Changzhou, PR China

  • Department of Gynecology, The First Affiliated Hospital of University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, PR China

  • Graduate School, Dalian Medical University, Dalian, PR China

  • Graduate School, Dalian Medical University, Dalian, PR China

  • Department of Gynecology, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Changzhou, PR China

  • Department of Gynecology, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Changzhou, PR China

  • Department of Gynecology, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Changzhou, PR China

  • Department of Gynecology, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Changzhou, PR China

  • Department of Gynecology, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Changzhou, PR China

  • Department of Gynecology, The First Affiliated Hospital of University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, PR China

  • Department of Gynecology, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Changzhou, PR China

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