Successful Kidney Transplantation in an Advanced Elderly at Federal Medical Center Abuja: A Case Presentation

Obiatuegwu Kenenna; Aniede Ernest; Agrawal Rajesh Kumar; Olawoye Tunde; Fidelis Lovely; Bioku Muftau; Anyabolu Michael; Saad Ahmed

doi:doi:10.11648/j.wjmcr.20250603.11

Case Report |

| Peer-Reviewed

Successful Kidney Transplantation in an Advanced Elderly at Federal Medical Center Abuja: A Case Presentation

Obiatuegwu Kenenna^*, Aniede Ernest

, Agrawal Rajesh Kumar

, Olawoye Tunde

, Fidelis Lovely

, Bioku Muftau

, Anyabolu Michael

, Saad Ahmed

Published in World Journal of Medical Case Reports (Volume 6, Issue 3)

Received: 18 June 2025 Accepted: 30 June 2025 Published: 23 July 2025

Views: Downloads:

Download PDF

Share This Article

Twitter
Linked In
Facebook

Abstract

Background: Kidney transplantation (KTP) in elderly can be challenging with fears of mortality that is unrelated to surgery. Generally, elderly patients are defined as individuals aged 65 years and older. These group of individuals has been further subdivide unto ‘early elderly’ or ‘late elderly’. KTP is a form of stress which invariably triggers off significant impactful metabolic response in these group of weak and delicate individuals. Objective: End stage renal disease (ESRD) occurs in all age groups and the prevalence increases with aging due to associated comorbid conditions like diabetes mellitus (DM) and hypertension. This co-morbidities are confirmed etiology of ESRD. The aim of this case presentation is to emphasize that age is not an absolute contraindication to KTP. The emphasis should rather dwell on careful patient selection, good surgical techniques as well as adequate post-operative care and follow up. Conclusion: We report a case of an 81 year old male patient with ESRD secondary to long term DM and hypertension who had kidney transplantation in our facility with impressive outcome. We had our fears prior to KTP as per advanced age, drug burden and compliance despite excellent HLA typing and cross matching. However we were able to navigate these challenges by use of branded immunosuppressive drugs, living related donor, good surgical techniques, regular follow up as well as engaging a domiciliary care giver in order to ensure strict drug compliance while envisaging long term graft survival.

Published in	World Journal of Medical Case Reports (Volume 6, Issue 3)
DOI	10.11648/j.wjmcr.20250603.11
Page(s)	20-26
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2025. Published by Science Publishing Group

Keywords

Kidney Transplantation, End Stage Renal Disease, Elderly, Hemodialysis, Quality of Life

References

[1]	Obiatuegwu Kenenna, Otabor Christopher, Agrawal Rajesh Kumar, Magnis Felix, Aremu Abayomi, Aniede Ernest, Olawoye Olatunde, Odinenu Theodora, Chikodili Ugochukwu. Kidney Transplantation: Our Experience in a Private Tertiary Center in Abuja. Science Journal of Clinical Medicine 2025; 14(2): 12-19. https://doi.org/10.11648/j.sjcm.20251402.11
[2]	Huang E, Segev DL, Rabb H. Kidney transplantation in the elderly. Semin Nephrol. 2009 Nov; 29(6): 621-35. https://doi.org/10.1016/j.semnephrol.2009.07.011
[3]	Hajime Orimo, Hideki Ito, Takao Suzuki, Atsushi Araki, Takayuki Hosoi, Motoji Sawabe. Reviewing the definition of “elderly”. Geriatrics and Gerontology International. 2006; 6(3): https://doi.org/10.1111/j.1447-0594.2006.00341.x
[4]	Eda Ünal, Aysel Özdemir. Old Age and Aging. October 2019. In book: Recent Studies in Health Sciences. Publisher: St. Kliment Ohridski University Press Sofia.
[5]	Wolfe RA, Ashby VB, Milford EL, Ojo AO, Ettenger RE, Agodoa LY, et al. Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant. N Engl J Med. 1999; 341: 1725–30. https://doi.org/10.1056/NEJM199912023412303
[6]	US Renal Data System. USRDS 2008 annual data report: atlas of end-stage renal disease in the United States. Bethesda, MD: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases; 2008.
[7]	Lemoine M, Guerrot D, Bertrand D. Transplantation rénale et sujet âgé: mise au point [Focusing on kidney transplantation in the elderly]. Nephrol Ther. 2018 Apr; 14(2): 71-80. French. https://doi.org/10.1016/j.nephro.2017.06.003 Epub 2017 Nov 22.
[8]	Adani GL, Baccarani U, Crestale S, Pravisani R, Isola M, Tulissi P, Vallone C, Nappi R, Risaliti A. Kidney Transplantation in Elderly Recipients: A Single-Center Experience. Transplant Proc. 2019 Jan-Feb; 51(1): 132-135. https://doi.org/10.1016/j.transproceed.2018.04.081 Epub 2018 Jun 30.
[9]	Ponticelli C, Podestà MA, Graziani G. Renal transplantation in elderly patients. How to select the candidates to the waiting list? Transplant Rev (Orlando). 2014 Oct; 28(4): 188-92. https://doi.org/10.1016/j.trre.2014.07.001 Epub 2014 Jul 31.
[10]	Silva RM, Leal R, Marques MG, Rodrigues L, Santos L, Romãozinho C, Alves R, Figueiredo A. Factors Influencing Short-Term Patient Survival in Elderly Kidney Transplant Recipients. Transplant Proc. 2023 Jul-Aug; 55(6): 1400-1403. https://doi.org/10.1016/j.transproceed.2023.05.006 Epub 2023 Jun 7.
[11]	Wang Y, Snoep JD, Hemmelder MH, van der Bogt KEA, Bos WJW, van der Boog PJM, Dekker FW, de Vries APJ, Meuleman Y. Outcomes after Kidney Transplantation, Let's Focus on the Patients' Perspectives. Clin Kidney J. 2021 Jan 20; 14(6): 1504-1513. https://doi.org/10.1093/ckj/sfab008
[12]	Keith DS. Transplantation in the elderly patient. Clin Geriatr Med. 2013 Aug; 29(3): 707-19. https://doi.org/10.1016/j.cger.2013.05.010
[13]	Snanoudj R. Transplantation rénale du sujet âgé: un bénéfice pour tous? [Kidney transplantation in the elderly: A benefit for all patients?]. Nephrol Ther. 2021 Apr; 17S: S115-S118. French. https://doi.org/10.1016/j.nephro.2020.02.007
[14]	Randall HB, Cao S, deVera ME. Transplantation in elderly patients. Arch Surg. 2003 Oct; 138(10): 1089-92. https://doi.org/10.1001/archsurg.138.10.1089
[15]	Heldal K, Leivestad T, Hartmann A, Svendsen MV, Lien BH, Midtvedt K. Kidney transplantation in the elderly--the Norwegian experience. Nephrol Dial Transplant. 2008 Mar; 23(3): 1026-31. https://doi.org/10.1093/ndt/gfm719 Epub 2007 Dec 13.
[16]	Kurschat C. Nierentransplantation im Alter [Kidney transplantation in old age]. Z Gerontol Geriatr. 2016 Aug; 49(6): 488-93. German. https://doi.org/10.1007/s00391-016-1118-x Epub 2016 Jul 27.
[17]	Ko EJ, Yang J, Ahn C, Kim MS, Han DJ, Kim SJ, Yang CW, Chung BH; Korean Organ Transplantation Registry Study Group. Clinical outcomes of kidney transplantation in older end-stage renal disease patients: A nationwide cohort study. Geriatr Gerontol Int. 2019 May; 19(5): 392-398. https://doi.org/10.1111/ggi.13630 Epub 2019 Feb 20.
[18]	Živčić-Ćosić S, Süsal C, Döhler B, Katalinić N, Markić D, Orlić L, Rački S, Španjol J, Trobonjača Z. Kidney Transplants from Elderly Donors: The Experience of a Reference Center in Croatia. Exp Clin Transplant. 2022 Jan; 20(1): 19-27. https://doi.org/10.6002/ect.2021.0366

Cite This Article

Plain Text BibTeX RIS

APA Style

Kenenna, O., Ernest, A., Kumar, A. R., Tunde, O., Lovely, F., et al. (2025). Successful Kidney Transplantation in an Advanced Elderly at Federal Medical Center Abuja: A Case Presentation. World Journal of Medical Case Reports, 6(3), 20-26. https://doi.org/10.11648/j.wjmcr.20250603.11

Copy | Download

ACS Style

Kenenna, O.; Ernest, A.; Kumar, A. R.; Tunde, O.; Lovely, F., et al. Successful Kidney Transplantation in an Advanced Elderly at Federal Medical Center Abuja: A Case Presentation. World J. Med. Case Rep. 2025, 6(3), 20-26. doi: 10.11648/j.wjmcr.20250603.11

Copy | Download

AMA Style

Kenenna O, Ernest A, Kumar AR, Tunde O, Lovely F, et al. Successful Kidney Transplantation in an Advanced Elderly at Federal Medical Center Abuja: A Case Presentation. World J Med Case Rep. 2025;6(3):20-26. doi: 10.11648/j.wjmcr.20250603.11

Copy | Download

@article{10.11648/j.wjmcr.20250603.11,
  author = {Obiatuegwu Kenenna and Aniede Ernest and Agrawal Rajesh Kumar and Olawoye Tunde and Fidelis Lovely and Bioku Muftau and Anyabolu Michael and Saad Ahmed},
  title = {Successful Kidney Transplantation in an Advanced Elderly at Federal Medical Center Abuja: A Case Presentation
},
  journal = {World Journal of Medical Case Reports},
  volume = {6},
  number = {3},
  pages = {20-26},
  doi = {10.11648/j.wjmcr.20250603.11},
  url = {https://doi.org/10.11648/j.wjmcr.20250603.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.wjmcr.20250603.11},
  abstract = {Background: Kidney transplantation (KTP) in elderly can be challenging with fears of mortality that is unrelated to surgery. Generally, elderly patients are defined as individuals aged 65 years and older. These group of individuals has been further subdivide unto ‘early elderly’ or ‘late elderly’. KTP is a form of stress which invariably triggers off significant impactful metabolic response in these group of weak and delicate individuals. Objective: End stage renal disease (ESRD) occurs in all age groups and the prevalence increases with aging due to associated comorbid conditions like diabetes mellitus (DM) and hypertension. This co-morbidities are confirmed etiology of ESRD. The aim of this case presentation is to emphasize that age is not an absolute contraindication to KTP. The emphasis should rather dwell on careful patient selection, good surgical techniques as well as adequate post-operative care and follow up. Conclusion: We report a case of an 81 year old male patient with ESRD secondary to long term DM and hypertension who had kidney transplantation in our facility with impressive outcome. We had our fears prior to KTP as per advanced age, drug burden and compliance despite excellent HLA typing and cross matching. However we were able to navigate these challenges by use of branded immunosuppressive drugs, living related donor, good surgical techniques, regular follow up as well as engaging a domiciliary care giver in order to ensure strict drug compliance while envisaging long term graft survival.},
 year = {2025}
}

Copy | Download

TY  - JOUR
T1  - Successful Kidney Transplantation in an Advanced Elderly at Federal Medical Center Abuja: A Case Presentation

AU  - Obiatuegwu Kenenna
AU  - Aniede Ernest
AU  - Agrawal Rajesh Kumar
AU  - Olawoye Tunde
AU  - Fidelis Lovely
AU  - Bioku Muftau
AU  - Anyabolu Michael
AU  - Saad Ahmed
Y1  - 2025/07/23
PY  - 2025
N1  - https://doi.org/10.11648/j.wjmcr.20250603.11
DO  - 10.11648/j.wjmcr.20250603.11
T2  - World Journal of Medical Case Reports
JF  - World Journal of Medical Case Reports
JO  - World Journal of Medical Case Reports
SP  - 20
EP  - 26
PB  - Science Publishing Group
SN  - 2994-726X
UR  - https://doi.org/10.11648/j.wjmcr.20250603.11
AB  - Background: Kidney transplantation (KTP) in elderly can be challenging with fears of mortality that is unrelated to surgery. Generally, elderly patients are defined as individuals aged 65 years and older. These group of individuals has been further subdivide unto ‘early elderly’ or ‘late elderly’. KTP is a form of stress which invariably triggers off significant impactful metabolic response in these group of weak and delicate individuals. Objective: End stage renal disease (ESRD) occurs in all age groups and the prevalence increases with aging due to associated comorbid conditions like diabetes mellitus (DM) and hypertension. This co-morbidities are confirmed etiology of ESRD. The aim of this case presentation is to emphasize that age is not an absolute contraindication to KTP. The emphasis should rather dwell on careful patient selection, good surgical techniques as well as adequate post-operative care and follow up. Conclusion: We report a case of an 81 year old male patient with ESRD secondary to long term DM and hypertension who had kidney transplantation in our facility with impressive outcome. We had our fears prior to KTP as per advanced age, drug burden and compliance despite excellent HLA typing and cross matching. However we were able to navigate these challenges by use of branded immunosuppressive drugs, living related donor, good surgical techniques, regular follow up as well as engaging a domiciliary care giver in order to ensure strict drug compliance while envisaging long term graft survival.
VL  - 6
IS  - 3
ER  -

Copy | Download

Author Information

Obiatuegwu Kenenna

Department of Surgery, Federal Medical Center Abuja, Abuja, Nigeria. Department of Surgery, Baze University Abuja, Abuja, Nigeria

Contact Email
Aniede Ernest

Department of Internal Medicine, Federal Medical Center Abuja, Abuja, Nigeria. Department of Medicine, Baze University Abuja, Abuja, Nigeria

http://orcid.org/0009-0006-4889-9061
Agrawal Rajesh Kumar

Department of Surgery, National Kidney Hospital, SAS Nagar Jalandhar, India

http://orcid.org/0009-0004-9422-7747
Olawoye Tunde

Department of Anesthesia, Federal Medical Center Abuja, Abuja, Nigeria. Department of Surgery, Baze University Abuja, Abuja, Nigeria

http://orcid.org/0000-0003-0183-1167
Fidelis Lovely

Department of Surgery, Federal Medical Center Abuja, Abuja, Nigeria

http://orcid.org/0000-0002-0457-5413
Bioku Muftau

Department of Surgery, Federal Medical Center Abuja, Abuja, Nigeria. Department of Surgery, Baze University Abuja, Abuja, Nigeria

http://orcid.org/0000-0002-4478-3495
Anyabolu Michael

Department of Surgery, Federal Medical Center Abuja, Abuja, Nigeria

http://orcid.org/0009-0007-8068-1166
Saad Ahmed

Department of Anatomic Pathology, Federal Medical Center Abuja, Abuja, Nigeria. Department of Surgery, Baze University Abuja, Abuja, Nigeria

http://orcid.org/0000-0001-8194-5943

Download PDF

Submit an Article

Sections

Plain Text BibTeX RIS

APA Style

Kenenna, O., Ernest, A., Kumar, A. R., Tunde, O., Lovely, F., et al. (2025). Successful Kidney Transplantation in an Advanced Elderly at Federal Medical Center Abuja: A Case Presentation. World Journal of Medical Case Reports, 6(3), 20-26. https://doi.org/10.11648/j.wjmcr.20250603.11

Copy | Download

ACS Style

Kenenna, O.; Ernest, A.; Kumar, A. R.; Tunde, O.; Lovely, F., et al. Successful Kidney Transplantation in an Advanced Elderly at Federal Medical Center Abuja: A Case Presentation. World J. Med. Case Rep. 2025, 6(3), 20-26. doi: 10.11648/j.wjmcr.20250603.11

Copy | Download

AMA Style

Kenenna O, Ernest A, Kumar AR, Tunde O, Lovely F, et al. Successful Kidney Transplantation in an Advanced Elderly at Federal Medical Center Abuja: A Case Presentation. World J Med Case Rep. 2025;6(3):20-26. doi: 10.11648/j.wjmcr.20250603.11

Copy | Download

@article{10.11648/j.wjmcr.20250603.11,
  author = {Obiatuegwu Kenenna and Aniede Ernest and Agrawal Rajesh Kumar and Olawoye Tunde and Fidelis Lovely and Bioku Muftau and Anyabolu Michael and Saad Ahmed},
  title = {Successful Kidney Transplantation in an Advanced Elderly at Federal Medical Center Abuja: A Case Presentation
},
  journal = {World Journal of Medical Case Reports},
  volume = {6},
  number = {3},
  pages = {20-26},
  doi = {10.11648/j.wjmcr.20250603.11},
  url = {https://doi.org/10.11648/j.wjmcr.20250603.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.wjmcr.20250603.11},
  abstract = {Background: Kidney transplantation (KTP) in elderly can be challenging with fears of mortality that is unrelated to surgery. Generally, elderly patients are defined as individuals aged 65 years and older. These group of individuals has been further subdivide unto ‘early elderly’ or ‘late elderly’. KTP is a form of stress which invariably triggers off significant impactful metabolic response in these group of weak and delicate individuals. Objective: End stage renal disease (ESRD) occurs in all age groups and the prevalence increases with aging due to associated comorbid conditions like diabetes mellitus (DM) and hypertension. This co-morbidities are confirmed etiology of ESRD. The aim of this case presentation is to emphasize that age is not an absolute contraindication to KTP. The emphasis should rather dwell on careful patient selection, good surgical techniques as well as adequate post-operative care and follow up. Conclusion: We report a case of an 81 year old male patient with ESRD secondary to long term DM and hypertension who had kidney transplantation in our facility with impressive outcome. We had our fears prior to KTP as per advanced age, drug burden and compliance despite excellent HLA typing and cross matching. However we were able to navigate these challenges by use of branded immunosuppressive drugs, living related donor, good surgical techniques, regular follow up as well as engaging a domiciliary care giver in order to ensure strict drug compliance while envisaging long term graft survival.},
 year = {2025}
}

Copy | Download

TY  - JOUR
T1  - Successful Kidney Transplantation in an Advanced Elderly at Federal Medical Center Abuja: A Case Presentation

AU  - Obiatuegwu Kenenna
AU  - Aniede Ernest
AU  - Agrawal Rajesh Kumar
AU  - Olawoye Tunde
AU  - Fidelis Lovely
AU  - Bioku Muftau
AU  - Anyabolu Michael
AU  - Saad Ahmed
Y1  - 2025/07/23
PY  - 2025
N1  - https://doi.org/10.11648/j.wjmcr.20250603.11
DO  - 10.11648/j.wjmcr.20250603.11
T2  - World Journal of Medical Case Reports
JF  - World Journal of Medical Case Reports
JO  - World Journal of Medical Case Reports
SP  - 20
EP  - 26
PB  - Science Publishing Group
SN  - 2994-726X
UR  - https://doi.org/10.11648/j.wjmcr.20250603.11
AB  - Background: Kidney transplantation (KTP) in elderly can be challenging with fears of mortality that is unrelated to surgery. Generally, elderly patients are defined as individuals aged 65 years and older. These group of individuals has been further subdivide unto ‘early elderly’ or ‘late elderly’. KTP is a form of stress which invariably triggers off significant impactful metabolic response in these group of weak and delicate individuals. Objective: End stage renal disease (ESRD) occurs in all age groups and the prevalence increases with aging due to associated comorbid conditions like diabetes mellitus (DM) and hypertension. This co-morbidities are confirmed etiology of ESRD. The aim of this case presentation is to emphasize that age is not an absolute contraindication to KTP. The emphasis should rather dwell on careful patient selection, good surgical techniques as well as adequate post-operative care and follow up. Conclusion: We report a case of an 81 year old male patient with ESRD secondary to long term DM and hypertension who had kidney transplantation in our facility with impressive outcome. We had our fears prior to KTP as per advanced age, drug burden and compliance despite excellent HLA typing and cross matching. However we were able to navigate these challenges by use of branded immunosuppressive drugs, living related donor, good surgical techniques, regular follow up as well as engaging a domiciliary care giver in order to ensure strict drug compliance while envisaging long term graft survival.
VL  - 6
IS  - 3
ER  -

Copy | Download