Risk Factors for Stroke Associated with HIV at Loandjili General Hospital in Pointe-Noire (Congo)

Prince Eliot Galieni Sounga Bandzouzi; Ghislain Armel Mpandzou; Raissa Mayanda; Josué Euberma Diatewa; Patience Moudeko M’foutou; Dina Happia Motoula-latou; Charles Godefroy Koubemba; Paul Macaire Ossou-nguiet; Donatien Moukassa

doi:doi:10.11648/j.cnn.20210504.16

Risk Factors for Stroke Associated with HIV at Loandjili General Hospital in Pointe-Noire (Congo)

Prince Eliot Galieni Sounga Bandzouzi, Ghislain Armel Mpandzou, Raissa Mayanda, Josué Euberma Diatewa, Patience Moudeko M’foutou, Dina Happia Motoula-latou, Charles Godefroy Koubemba, Paul Macaire Ossou-nguiet, Donatien Moukassa

Published in Clinical Neurology and Neuroscience (Volume 5, Issue 4)

Received: 3 November 2021 Accepted: 19 November 2021 Published: 27 November 2021

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Abstract

Introduction: HIV infection and stroke constitute a major public health problem due to their morbidity and mortality. In people living with HIV the risk of developing a stroke is high. Objective: To establish the causal link between HIV and the onset of stroke in order to determine the risk factors for stroke associated with HIV at loandjili general hospital. Patients and Methods: It was a case-control study, prospective from January to July 2019, carried out in the department of Pointe-Noire, including any patient hospitalized for stroke confirmed by brain scan, any patient hospitalized or coming for an outpatient consultation. pathologies unrelated to stroke. The statistical analysis was carried out using the EPI info 7.2 software. Results: Two hundred patients were included in our study, including 100 cases and 100 controls. The relative frequency of HIV was 17% in cases versus 43% in controls. Young age was the risk factor for stroke associated with HIV. This risk factor was potentiated by immunosuppression of CD4 + T lymphocytes. Seventy-eight (78%) of stroke + / HIV + patients had a CD4 + count <200 / mm3. DALY was the predominant mechanism of injury with a frequency of 56% in people living with HIV. Conclusion: Stroke-HIV co-morbidity is frequent in Pointe-Noire. The risk factors for stroke / HIV + are dominated by young age. However, our study did not show a causal link between HIV and the onset of stroke.

Published in	Clinical Neurology and Neuroscience (Volume 5, Issue 4)
DOI	10.11648/j.cnn.20210504.16
Page(s)	111-116
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Stroke, HIV, Case-controls, Pointe Noire, Congo

References

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Prince Eliot Galieni Sounga Bandzouzi, Ghislain Armel Mpandzou, Raissa Mayanda, Josué Euberma Diatewa, Patience Moudeko M’foutou, et al. (2021). Risk Factors for Stroke Associated with HIV at Loandjili General Hospital in Pointe-Noire (Congo). Clinical Neurology and Neuroscience, 5(4), 111-116. https://doi.org/10.11648/j.cnn.20210504.16

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Prince Eliot Galieni Sounga Bandzouzi; Ghislain Armel Mpandzou; Raissa Mayanda; Josué Euberma Diatewa; Patience Moudeko M’foutou, et al. Risk Factors for Stroke Associated with HIV at Loandjili General Hospital in Pointe-Noire (Congo). Clin. Neurol. Neurosci. 2021, 5(4), 111-116. doi: 10.11648/j.cnn.20210504.16

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AMA Style

Prince Eliot Galieni Sounga Bandzouzi, Ghislain Armel Mpandzou, Raissa Mayanda, Josué Euberma Diatewa, Patience Moudeko M’foutou, et al. Risk Factors for Stroke Associated with HIV at Loandjili General Hospital in Pointe-Noire (Congo). Clin Neurol Neurosci. 2021;5(4):111-116. doi: 10.11648/j.cnn.20210504.16

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@article{10.11648/j.cnn.20210504.16,
  author = {Prince Eliot Galieni Sounga Bandzouzi and Ghislain Armel Mpandzou and Raissa Mayanda and Josué Euberma Diatewa and Patience Moudeko M’foutou and Dina Happia Motoula-latou and Charles Godefroy Koubemba and Paul Macaire Ossou-nguiet and Donatien Moukassa},
  title = {Risk Factors for Stroke Associated with HIV at Loandjili General Hospital in Pointe-Noire (Congo)},
  journal = {Clinical Neurology and Neuroscience},
  volume = {5},
  number = {4},
  pages = {111-116},
  doi = {10.11648/j.cnn.20210504.16},
  url = {https://doi.org/10.11648/j.cnn.20210504.16},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cnn.20210504.16},
  abstract = {Introduction: HIV infection and stroke constitute a major public health problem due to their morbidity and mortality. In people living with HIV the risk of developing a stroke is high. Objective: To establish the causal link between HIV and the onset of stroke in order to determine the risk factors for stroke associated with HIV at loandjili general hospital. Patients and Methods: It was a case-control study, prospective from January to July 2019, carried out in the department of Pointe-Noire, including any patient hospitalized for stroke confirmed by brain scan, any patient hospitalized or coming for an outpatient consultation. pathologies unrelated to stroke. The statistical analysis was carried out using the EPI info 7.2 software. Results: Two hundred patients were included in our study, including 100 cases and 100 controls. The relative frequency of HIV was 17% in cases versus 43% in controls. Young age was the risk factor for stroke associated with HIV. This risk factor was potentiated by immunosuppression of CD4 + T lymphocytes. Seventy-eight (78%) of stroke + / HIV + patients had a CD4 + count <200 / mm3. DALY was the predominant mechanism of injury with a frequency of 56% in people living with HIV. Conclusion: Stroke-HIV co-morbidity is frequent in Pointe-Noire. The risk factors for stroke / HIV + are dominated by young age. However, our study did not show a causal link between HIV and the onset of stroke.},
 year = {2021}
}

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TY - JOUR
T1 - Risk Factors for Stroke Associated with HIV at Loandjili General Hospital in Pointe-Noire (Congo)
AU - Prince Eliot Galieni Sounga Bandzouzi
AU - Ghislain Armel Mpandzou
AU - Raissa Mayanda
AU - Josué Euberma Diatewa
AU - Patience Moudeko M’foutou
AU - Dina Happia Motoula-latou
AU - Charles Godefroy Koubemba
AU - Paul Macaire Ossou-nguiet
AU - Donatien Moukassa
Y1 - 2021/11/27
PY - 2021
N1 - https://doi.org/10.11648/j.cnn.20210504.16
DO - 10.11648/j.cnn.20210504.16
T2 - Clinical Neurology and Neuroscience
JF - Clinical Neurology and Neuroscience
JO - Clinical Neurology and Neuroscience
SP - 111
EP - 116
PB - Science Publishing Group
SN - 2578-8930
UR - https://doi.org/10.11648/j.cnn.20210504.16
AB - Introduction: HIV infection and stroke constitute a major public health problem due to their morbidity and mortality. In people living with HIV the risk of developing a stroke is high. Objective: To establish the causal link between HIV and the onset of stroke in order to determine the risk factors for stroke associated with HIV at loandjili general hospital. Patients and Methods: It was a case-control study, prospective from January to July 2019, carried out in the department of Pointe-Noire, including any patient hospitalized for stroke confirmed by brain scan, any patient hospitalized or coming for an outpatient consultation. pathologies unrelated to stroke. The statistical analysis was carried out using the EPI info 7.2 software. Results: Two hundred patients were included in our study, including 100 cases and 100 controls. The relative frequency of HIV was 17% in cases versus 43% in controls. Young age was the risk factor for stroke associated with HIV. This risk factor was potentiated by immunosuppression of CD4 + T lymphocytes. Seventy-eight (78%) of stroke + / HIV + patients had a CD4 + count <200 / mm3. DALY was the predominant mechanism of injury with a frequency of 56% in people living with HIV. Conclusion: Stroke-HIV co-morbidity is frequent in Pointe-Noire. The risk factors for stroke / HIV + are dominated by young age. However, our study did not show a causal link between HIV and the onset of stroke.
VL - 5
IS - 4
ER -

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Author Information

Prince Eliot Galieni Sounga Bandzouzi

Faculty of Health Sciences, Marien N’GOUABI University, Brazzaville, Republic of Congo
Ghislain Armel Mpandzou

Faculty of Health Sciences, Marien N’GOUABI University, Brazzaville, Republic of Congo
Raissa Mayanda

Faculty of Health Sciences, Marien N’GOUABI University, Brazzaville, Republic of Congo
Josué Euberma Diatewa

Faculty of Health Sciences, Marien N’GOUABI University, Brazzaville, Republic of Congo
Patience Moudeko M’foutou

Department of Neurology, Loandjili General Hospital, Pointe-Noire, Republic of the Congo
Dina Happia Motoula-latou

Faculty of Health Sciences, Marien N’GOUABI University, Brazzaville, Republic of Congo
Charles Godefroy Koubemba

Department of Neurology, Loandjili General Hospital, Pointe-Noire, Republic of the Congo
Paul Macaire Ossou-nguiet

Faculty of Health Sciences, Marien N’GOUABI University, Brazzaville, Republic of Congo
Donatien Moukassa

Faculty of Health Sciences, Marien N’GOUABI University, Brazzaville, Republic of Congo

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APA Style

Prince Eliot Galieni Sounga Bandzouzi, Ghislain Armel Mpandzou, Raissa Mayanda, Josué Euberma Diatewa, Patience Moudeko M’foutou, et al. (2021). Risk Factors for Stroke Associated with HIV at Loandjili General Hospital in Pointe-Noire (Congo). Clinical Neurology and Neuroscience, 5(4), 111-116. https://doi.org/10.11648/j.cnn.20210504.16

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Prince Eliot Galieni Sounga Bandzouzi; Ghislain Armel Mpandzou; Raissa Mayanda; Josué Euberma Diatewa; Patience Moudeko M’foutou, et al. Risk Factors for Stroke Associated with HIV at Loandjili General Hospital in Pointe-Noire (Congo). Clin. Neurol. Neurosci. 2021, 5(4), 111-116. doi: 10.11648/j.cnn.20210504.16

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Prince Eliot Galieni Sounga Bandzouzi, Ghislain Armel Mpandzou, Raissa Mayanda, Josué Euberma Diatewa, Patience Moudeko M’foutou, et al. Risk Factors for Stroke Associated with HIV at Loandjili General Hospital in Pointe-Noire (Congo). Clin Neurol Neurosci. 2021;5(4):111-116. doi: 10.11648/j.cnn.20210504.16

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@article{10.11648/j.cnn.20210504.16,
  author = {Prince Eliot Galieni Sounga Bandzouzi and Ghislain Armel Mpandzou and Raissa Mayanda and Josué Euberma Diatewa and Patience Moudeko M’foutou and Dina Happia Motoula-latou and Charles Godefroy Koubemba and Paul Macaire Ossou-nguiet and Donatien Moukassa},
  title = {Risk Factors for Stroke Associated with HIV at Loandjili General Hospital in Pointe-Noire (Congo)},
  journal = {Clinical Neurology and Neuroscience},
  volume = {5},
  number = {4},
  pages = {111-116},
  doi = {10.11648/j.cnn.20210504.16},
  url = {https://doi.org/10.11648/j.cnn.20210504.16},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cnn.20210504.16},
  abstract = {Introduction: HIV infection and stroke constitute a major public health problem due to their morbidity and mortality. In people living with HIV the risk of developing a stroke is high. Objective: To establish the causal link between HIV and the onset of stroke in order to determine the risk factors for stroke associated with HIV at loandjili general hospital. Patients and Methods: It was a case-control study, prospective from January to July 2019, carried out in the department of Pointe-Noire, including any patient hospitalized for stroke confirmed by brain scan, any patient hospitalized or coming for an outpatient consultation. pathologies unrelated to stroke. The statistical analysis was carried out using the EPI info 7.2 software. Results: Two hundred patients were included in our study, including 100 cases and 100 controls. The relative frequency of HIV was 17% in cases versus 43% in controls. Young age was the risk factor for stroke associated with HIV. This risk factor was potentiated by immunosuppression of CD4 + T lymphocytes. Seventy-eight (78%) of stroke + / HIV + patients had a CD4 + count <200 / mm3. DALY was the predominant mechanism of injury with a frequency of 56% in people living with HIV. Conclusion: Stroke-HIV co-morbidity is frequent in Pointe-Noire. The risk factors for stroke / HIV + are dominated by young age. However, our study did not show a causal link between HIV and the onset of stroke.},
 year = {2021}
}

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