Cerebrospinal fluid (CSF) rhinorrhoea is the leakage of CSF from the subarachnoid space into the nasal cavity. A cerebrospinal fluid leak from intracranial cavity to nasal respiratory tract has the potential to produce fulminant meningitis because of the risk of an ascending infection. Recurrent spontaneous CSF rhinorrhoea is definitely a life-threatening entity that can be preventable with timely intervention. This case report describes the clinical course of a 51 year old obese female with recurrent episodes of spontaneous CSF rhinorrhoea presenting with high grade fever, vomiting, headache and new-onset seizure. She was evaluated for meningoencephalitis and CSF culture revealed growth of Staphylococcus arlettae. Patient improved with ceftriaxone, vancomycin and levetiracetam and was advised for early surgical repair. A longer duration of nasal discharge of CSF has greater risk of morbidity/mortality due to ascending CNS infection. The episodes of spontaneous CNS rhinorrhoea can pass by unnoticed and can also be missed for rhinosinusitis. A high suspicion of diagnosis can lead to early detection of this condition and better outcome. Treatment decisions should be dictated by the severity of neurological decline during the emergency period and the presence/absence of associated intracranial lesions. The emphasis for timely surgical repair should be advocated for better outcome.
| Published in | Clinical Neurology and Neuroscience (Volume 5, Issue 4) |
| DOI | 10.11648/j.cnn.20210504.18 |
| Page(s) | 124-128 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2021. Published by Science Publishing Group |
CSF Rhinorrhea, Meningoencephalitis, Staphylococcus Arlettae
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APA Style
Shweta Pandey, Rajarshi Chakraborty. (2021). A Case of Recurrent Spontaneous CSF Rhinorrhoea with Meningoencephalitis. Clinical Neurology and Neuroscience, 5(4), 124-128. https://doi.org/10.11648/j.cnn.20210504.18
ACS Style
Shweta Pandey; Rajarshi Chakraborty. A Case of Recurrent Spontaneous CSF Rhinorrhoea with Meningoencephalitis. Clin. Neurol. Neurosci. 2021, 5(4), 124-128. doi: 10.11648/j.cnn.20210504.18
AMA Style
Shweta Pandey, Rajarshi Chakraborty. A Case of Recurrent Spontaneous CSF Rhinorrhoea with Meningoencephalitis. Clin Neurol Neurosci. 2021;5(4):124-128. doi: 10.11648/j.cnn.20210504.18
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Download@article{10.11648/j.cnn.20210504.18,
author = {Shweta Pandey and Rajarshi Chakraborty},
title = {A Case of Recurrent Spontaneous CSF Rhinorrhoea with Meningoencephalitis},
journal = {Clinical Neurology and Neuroscience},
volume = {5},
number = {4},
pages = {124-128},
doi = {10.11648/j.cnn.20210504.18},
url = {https://doi.org/10.11648/j.cnn.20210504.18},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cnn.20210504.18},
abstract = {Cerebrospinal fluid (CSF) rhinorrhoea is the leakage of CSF from the subarachnoid space into the nasal cavity. A cerebrospinal fluid leak from intracranial cavity to nasal respiratory tract has the potential to produce fulminant meningitis because of the risk of an ascending infection. Recurrent spontaneous CSF rhinorrhoea is definitely a life-threatening entity that can be preventable with timely intervention. This case report describes the clinical course of a 51 year old obese female with recurrent episodes of spontaneous CSF rhinorrhoea presenting with high grade fever, vomiting, headache and new-onset seizure. She was evaluated for meningoencephalitis and CSF culture revealed growth of Staphylococcus arlettae. Patient improved with ceftriaxone, vancomycin and levetiracetam and was advised for early surgical repair. A longer duration of nasal discharge of CSF has greater risk of morbidity/mortality due to ascending CNS infection. The episodes of spontaneous CNS rhinorrhoea can pass by unnoticed and can also be missed for rhinosinusitis. A high suspicion of diagnosis can lead to early detection of this condition and better outcome. Treatment decisions should be dictated by the severity of neurological decline during the emergency period and the presence/absence of associated intracranial lesions. The emphasis for timely surgical repair should be advocated for better outcome.},
year = {2021}
}
TY - JOUR T1 - A Case of Recurrent Spontaneous CSF Rhinorrhoea with Meningoencephalitis AU - Shweta Pandey AU - Rajarshi Chakraborty Y1 - 2021/12/24 PY - 2021 N1 - https://doi.org/10.11648/j.cnn.20210504.18 DO - 10.11648/j.cnn.20210504.18 T2 - Clinical Neurology and Neuroscience JF - Clinical Neurology and Neuroscience JO - Clinical Neurology and Neuroscience SP - 124 EP - 128 PB - Science Publishing Group SN - 2578-8930 UR - https://doi.org/10.11648/j.cnn.20210504.18 AB - Cerebrospinal fluid (CSF) rhinorrhoea is the leakage of CSF from the subarachnoid space into the nasal cavity. A cerebrospinal fluid leak from intracranial cavity to nasal respiratory tract has the potential to produce fulminant meningitis because of the risk of an ascending infection. Recurrent spontaneous CSF rhinorrhoea is definitely a life-threatening entity that can be preventable with timely intervention. This case report describes the clinical course of a 51 year old obese female with recurrent episodes of spontaneous CSF rhinorrhoea presenting with high grade fever, vomiting, headache and new-onset seizure. She was evaluated for meningoencephalitis and CSF culture revealed growth of Staphylococcus arlettae. Patient improved with ceftriaxone, vancomycin and levetiracetam and was advised for early surgical repair. A longer duration of nasal discharge of CSF has greater risk of morbidity/mortality due to ascending CNS infection. The episodes of spontaneous CNS rhinorrhoea can pass by unnoticed and can also be missed for rhinosinusitis. A high suspicion of diagnosis can lead to early detection of this condition and better outcome. Treatment decisions should be dictated by the severity of neurological decline during the emergency period and the presence/absence of associated intracranial lesions. The emphasis for timely surgical repair should be advocated for better outcome. VL - 5 IS - 4 ER -
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