Intensive Treatment of Mania with Traditional Chinese Medicine: Meta-analysis of Effects of Chinese and Western Integrative Medicine for the Treatment of Mania in China

Sun Fengli; Gao Zhihan; Zhu Jianfeng; Jin Rui; Li Bingling; Jin Weidong

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Intensive Treatment of Mania with Traditional Chinese Medicine: Meta-analysis of Effects of Chinese and Western Integrative Medicine for the Treatment of Mania in China

Sun Fengli, Gao Zhihan, Zhu Jianfeng, Jin Rui, Li Bingling, Jin Weidong

Published in Asia-Pacific Journal of Chinese Medicine (Volume 1, Issue 1)

Received: 8 November 2018 Accepted: 19 December 2018 Published: 21 December 2018

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Abstract

At present, the treatment of mania with bipolar disorder mainly was used with mood stabilizers or mood stabilizers combined with atypical antipsychotic drugs. In China, traditional Chinese medicine（TCM）or TCM intergrated with western medicine is also one of the important methods of treating mania，which have been a trend because less side effect and higher accepbility.This study is assessing the differences of effects between Chinese and western integrative medicine(CWIM) and single western medicine in the treatment of mania. Searches were applied to the following electronic databases in china: Chinese Biomedical Database (CBM), China National Knowledge Infrastructure (CNKI), WANFANG and Chinese Social Sciences Citation Index (VIP) databases.The15 studies articles meeting our criteria were analyzed by based-evidence medicine, comparing their difference in changes of symptoms, efficacy rate. The lower manic symptoms in CWIM group than single western medicine group were found (Z=88.76, P<0.00001, WMD=-5.82, 95%CI -5.94~-5.69). It is suggested that the combination of Chinese medicine and Western medicine is more effective than western medicine in improving manic symptoms. The very significant higher effective rate in CWIM group than single western medicine group were found (78.9%vs67.2%, Z=4.77, P<0.00001, OR=1.90, 95%CI 1.46~2.48). It is also suggested that the combination of Chinese medicine and Western medicine is more effective than western medicine alone.Conclusion: These results show that effect of CWIM is better than single western medicine in the treatment of mania of bipolar disorder.

Published in	Asia-Pacific Journal of Chinese Medicine (Volume 1, Issue 1)
Page(s)	1-4
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2018. Published by Science Publishing Group

Keywords

Mania, Chinese and Western Integrative Medicine, Mood Stabilizer, Antipsychotic, Meta-analysis

References

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APA Style

Sun Fengli, Gao Zhihan, Zhu Jianfeng, Jin Rui, Li Bingling, et al. (2018). Intensive Treatment of Mania with Traditional Chinese Medicine: Meta-analysis of Effects of Chinese and Western Integrative Medicine for the Treatment of Mania in China. Asia-Pacific Journal of Chinese Medicine, 1(1), 1-4.

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ACS Style

Sun Fengli; Gao Zhihan; Zhu Jianfeng; Jin Rui; Li Bingling, et al. Intensive Treatment of Mania with Traditional Chinese Medicine: Meta-analysis of Effects of Chinese and Western Integrative Medicine for the Treatment of Mania in China. Asia-Pac. J. Chin. Med. 2018, 1(1), 1-4.

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AMA Style

Sun Fengli, Gao Zhihan, Zhu Jianfeng, Jin Rui, Li Bingling, et al. Intensive Treatment of Mania with Traditional Chinese Medicine: Meta-analysis of Effects of Chinese and Western Integrative Medicine for the Treatment of Mania in China. Asia-Pac J Chin Med. 2018;1(1):1-4.

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@article{10035004,
  author = {Sun Fengli and Gao Zhihan and Zhu Jianfeng and Jin Rui and Li Bingling and Jin Weidong},
  title = {Intensive Treatment of Mania with Traditional Chinese Medicine: Meta-analysis of Effects of Chinese and Western Integrative Medicine for the Treatment of Mania in China},
  journal = {Asia-Pacific Journal of Chinese Medicine},
  volume = {1},
  number = {1},
  pages = {1-4},
  url = {https://www.sciencepublishinggroup.com/article/10035004},
  abstract = {At present, the treatment of mania with bipolar disorder mainly was used with mood stabilizers or mood stabilizers combined with atypical antipsychotic drugs. In China, traditional Chinese medicine（TCM）or TCM intergrated with western medicine is also one of the important methods of treating mania，which have been a trend because less side effect and higher accepbility.This study is assessing the differences of effects between Chinese and western integrative medicine(CWIM) and single western medicine in the treatment of mania.  Searches were applied to the following electronic databases in china: Chinese Biomedical Database (CBM), China National Knowledge Infrastructure (CNKI), WANFANG and Chinese Social Sciences Citation Index (VIP) databases.The15 studies articles meeting our criteria were analyzed by based-evidence medicine, comparing their difference in changes of symptoms, efficacy rate. The lower manic symptoms in CWIM group than single western medicine group were found (Z=88.76, P<0.00001, WMD=-5.82, 95%CI -5.94~-5.69). It is suggested that the combination of Chinese medicine and Western medicine is more effective than western medicine in improving manic symptoms. The very significant higher effective rate in CWIM group than single western medicine group were found (78.9%vs67.2%, Z=4.77, P<0.00001, OR=1.90, 95%CI 1.46~2.48). It is also suggested that the combination of Chinese medicine and Western medicine is more effective than western medicine alone.Conclusion: These results show that effect of CWIM is better than single western medicine in the treatment of mania of bipolar disorder.},
 year = {2018}
}

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TY  - JOUR
T1  - Intensive Treatment of Mania with Traditional Chinese Medicine: Meta-analysis of Effects of Chinese and Western Integrative Medicine for the Treatment of Mania in China
AU  - Sun Fengli
AU  - Gao Zhihan
AU  - Zhu Jianfeng
AU  - Jin Rui
AU  - Li Bingling
AU  - Jin Weidong
Y1  - 2018/12/21
PY  - 2018
T2  - Asia-Pacific Journal of Chinese Medicine
JF  - Asia-Pacific Journal of Chinese Medicine
JO  - Asia-Pacific Journal of Chinese Medicine
SP  - 1
EP  - 4
PB  - Science Publishing Group
UR  - http://www.sciencepg.com/article/10035004
AB  - At present, the treatment of mania with bipolar disorder mainly was used with mood stabilizers or mood stabilizers combined with atypical antipsychotic drugs. In China, traditional Chinese medicine（TCM）or TCM intergrated with western medicine is also one of the important methods of treating mania，which have been a trend because less side effect and higher accepbility.This study is assessing the differences of effects between Chinese and western integrative medicine(CWIM) and single western medicine in the treatment of mania.  Searches were applied to the following electronic databases in china: Chinese Biomedical Database (CBM), China National Knowledge Infrastructure (CNKI), WANFANG and Chinese Social Sciences Citation Index (VIP) databases.The15 studies articles meeting our criteria were analyzed by based-evidence medicine, comparing their difference in changes of symptoms, efficacy rate. The lower manic symptoms in CWIM group than single western medicine group were found (Z=88.76, P<0.00001, WMD=-5.82, 95%CI -5.94~-5.69). It is suggested that the combination of Chinese medicine and Western medicine is more effective than western medicine in improving manic symptoms. The very significant higher effective rate in CWIM group than single western medicine group were found (78.9%vs67.2%, Z=4.77, P<0.00001, OR=1.90, 95%CI 1.46~2.48). It is also suggested that the combination of Chinese medicine and Western medicine is more effective than western medicine alone.Conclusion: These results show that effect of CWIM is better than single western medicine in the treatment of mania of bipolar disorder.
VL  - 1
IS  - 1
ER  -

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Author Information

Sun Fengli

Department of Psychiatry, Zhejiang Province Tongde Hospital, Zhejiang Prouince Mental health Center, Hangzhou, China
Gao Zhihan

Graduate School, Zhejiang Chinese Medical University, Hangzhou, China
Zhu Jianfeng

Graduate School, Zhejiang Chinese Medical University, Hangzhou, China
Jin Rui

Department of Pharmacology, Zhejiang Province Tongde Hospital, Hangzhou, China
Li Bingling

Department of Psychiatry, Zhejiang Province Tongde Hospital, Zhejiang Prouince Mental health Center, Hangzhou, China
Jin Weidong

Department of Psychiatry, Zhejiang Province Tongde Hospital, Zhejiang Prouince Mental health Center, Hangzhou, China

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APA Style

Sun Fengli, Gao Zhihan, Zhu Jianfeng, Jin Rui, Li Bingling, et al. (2018). Intensive Treatment of Mania with Traditional Chinese Medicine: Meta-analysis of Effects of Chinese and Western Integrative Medicine for the Treatment of Mania in China. Asia-Pacific Journal of Chinese Medicine, 1(1), 1-4.

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ACS Style

Sun Fengli; Gao Zhihan; Zhu Jianfeng; Jin Rui; Li Bingling, et al. Intensive Treatment of Mania with Traditional Chinese Medicine: Meta-analysis of Effects of Chinese and Western Integrative Medicine for the Treatment of Mania in China. Asia-Pac. J. Chin. Med. 2018, 1(1), 1-4.

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AMA Style

Sun Fengli, Gao Zhihan, Zhu Jianfeng, Jin Rui, Li Bingling, et al. Intensive Treatment of Mania with Traditional Chinese Medicine: Meta-analysis of Effects of Chinese and Western Integrative Medicine for the Treatment of Mania in China. Asia-Pac J Chin Med. 2018;1(1):1-4.

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@article{10035004,
  author = {Sun Fengli and Gao Zhihan and Zhu Jianfeng and Jin Rui and Li Bingling and Jin Weidong},
  title = {Intensive Treatment of Mania with Traditional Chinese Medicine: Meta-analysis of Effects of Chinese and Western Integrative Medicine for the Treatment of Mania in China},
  journal = {Asia-Pacific Journal of Chinese Medicine},
  volume = {1},
  number = {1},
  pages = {1-4},
  url = {https://www.sciencepublishinggroup.com/article/10035004},
  abstract = {At present, the treatment of mania with bipolar disorder mainly was used with mood stabilizers or mood stabilizers combined with atypical antipsychotic drugs. In China, traditional Chinese medicine（TCM）or TCM intergrated with western medicine is also one of the important methods of treating mania，which have been a trend because less side effect and higher accepbility.This study is assessing the differences of effects between Chinese and western integrative medicine(CWIM) and single western medicine in the treatment of mania.  Searches were applied to the following electronic databases in china: Chinese Biomedical Database (CBM), China National Knowledge Infrastructure (CNKI), WANFANG and Chinese Social Sciences Citation Index (VIP) databases.The15 studies articles meeting our criteria were analyzed by based-evidence medicine, comparing their difference in changes of symptoms, efficacy rate. The lower manic symptoms in CWIM group than single western medicine group were found (Z=88.76, P<0.00001, WMD=-5.82, 95%CI -5.94~-5.69). It is suggested that the combination of Chinese medicine and Western medicine is more effective than western medicine in improving manic symptoms. The very significant higher effective rate in CWIM group than single western medicine group were found (78.9%vs67.2%, Z=4.77, P<0.00001, OR=1.90, 95%CI 1.46~2.48). It is also suggested that the combination of Chinese medicine and Western medicine is more effective than western medicine alone.Conclusion: These results show that effect of CWIM is better than single western medicine in the treatment of mania of bipolar disorder.},
 year = {2018}
}

Copy | Download

TY  - JOUR
T1  - Intensive Treatment of Mania with Traditional Chinese Medicine: Meta-analysis of Effects of Chinese and Western Integrative Medicine for the Treatment of Mania in China
AU  - Sun Fengli
AU  - Gao Zhihan
AU  - Zhu Jianfeng
AU  - Jin Rui
AU  - Li Bingling
AU  - Jin Weidong
Y1  - 2018/12/21
PY  - 2018
T2  - Asia-Pacific Journal of Chinese Medicine
JF  - Asia-Pacific Journal of Chinese Medicine
JO  - Asia-Pacific Journal of Chinese Medicine
SP  - 1
EP  - 4
PB  - Science Publishing Group
UR  - http://www.sciencepg.com/article/10035004
AB  - At present, the treatment of mania with bipolar disorder mainly was used with mood stabilizers or mood stabilizers combined with atypical antipsychotic drugs. In China, traditional Chinese medicine（TCM）or TCM intergrated with western medicine is also one of the important methods of treating mania，which have been a trend because less side effect and higher accepbility.This study is assessing the differences of effects between Chinese and western integrative medicine(CWIM) and single western medicine in the treatment of mania.  Searches were applied to the following electronic databases in china: Chinese Biomedical Database (CBM), China National Knowledge Infrastructure (CNKI), WANFANG and Chinese Social Sciences Citation Index (VIP) databases.The15 studies articles meeting our criteria were analyzed by based-evidence medicine, comparing their difference in changes of symptoms, efficacy rate. The lower manic symptoms in CWIM group than single western medicine group were found (Z=88.76, P<0.00001, WMD=-5.82, 95%CI -5.94~-5.69). It is suggested that the combination of Chinese medicine and Western medicine is more effective than western medicine in improving manic symptoms. The very significant higher effective rate in CWIM group than single western medicine group were found (78.9%vs67.2%, Z=4.77, P<0.00001, OR=1.90, 95%CI 1.46~2.48). It is also suggested that the combination of Chinese medicine and Western medicine is more effective than western medicine alone.Conclusion: These results show that effect of CWIM is better than single western medicine in the treatment of mania of bipolar disorder.
VL  - 1
IS  - 1
ER  -

Copy | Download