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Research Progress of Apoptosis Inhibitory Protein Survivin in Gastric Cancer

Received: 24 March 2024     Accepted: 24 March 2024     Published: 25 March 2024
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Abstract

Survivin is an important member of the apoptosis inhibitory protein family, which plays an important role in suppressing apoptosis, promoting proliferation and vascular formation. The occurrence and development of tumors are related to apoptosis and imbalance of proliferation. Gastric cancer is the most common malignant tumor in the digestive system. Due to the inadequate symptoms of early symptoms, most of them have entered the middle and late stages during diagnosis. It is easy to relapse and metastasize. The mortality rate is high, which seriously endangers human health. Research have found that Survivin expresses high in gastric cancer tissue, participating in the proliferation of tumor cells, inhibiting apoptosis and the formation of blood vessels, and is of great significance to the diagnosis, judgment transfer and prognosis evaluation of gastric cancer, especially the value of combined with a number of indicators is greater. Therefore, finding an early diagnosis and judging the ideal tumor logo combination of the early diagnosis and judgment of the prognosis is important. This article reviews the biological characteristics of Survivin and its research progress in gastric cancer, so as to provide theoretical basis for the diagnosis of gastric cancer and new ideas for the successful prevention and treatment of tumors.

Published in American Journal of Health Research (Volume 12, Issue 2)
DOI 10.11648/j.ajhr.20241202.12
Page(s) 25-36
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Apoptosis Inhibiting Protein, Survivin, Gastric Cancer, Prognosis

References
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    Jianzhang, H., Shuli, Z., Jiyong, L., Hongyan, L., Zhenjiang, H. (2024). Research Progress of Apoptosis Inhibitory Protein Survivin in Gastric Cancer. American Journal of Health Research, 12(2), 25-36. https://doi.org/10.11648/j.ajhr.20241202.12

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    Jianzhang, H.; Shuli, Z.; Jiyong, L.; Hongyan, L.; Zhenjiang, H. Research Progress of Apoptosis Inhibitory Protein Survivin in Gastric Cancer. Am. J. Health Res. 2024, 12(2), 25-36. doi: 10.11648/j.ajhr.20241202.12

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    AMA Style

    Jianzhang H, Shuli Z, Jiyong L, Hongyan L, Zhenjiang H. Research Progress of Apoptosis Inhibitory Protein Survivin in Gastric Cancer. Am J Health Res. 2024;12(2):25-36. doi: 10.11648/j.ajhr.20241202.12

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  • @article{10.11648/j.ajhr.20241202.12,
      author = {Hou Jianzhang and Zhang Shuli and Li Jiyong and Li Hongyan and Hou Zhenjiang},
      title = {Research Progress of Apoptosis Inhibitory Protein Survivin in Gastric Cancer},
      journal = {American Journal of Health Research},
      volume = {12},
      number = {2},
      pages = {25-36},
      doi = {10.11648/j.ajhr.20241202.12},
      url = {https://doi.org/10.11648/j.ajhr.20241202.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajhr.20241202.12},
      abstract = {Survivin is an important member of the apoptosis inhibitory protein family, which plays an important role in suppressing apoptosis, promoting proliferation and vascular formation. The occurrence and development of tumors are related to apoptosis and imbalance of proliferation. Gastric cancer is the most common malignant tumor in the digestive system. Due to the inadequate symptoms of early symptoms, most of them have entered the middle and late stages during diagnosis. It is easy to relapse and metastasize. The mortality rate is high, which seriously endangers human health. Research have found that Survivin expresses high in gastric cancer tissue, participating in the proliferation of tumor cells, inhibiting apoptosis and the formation of blood vessels, and is of great significance to the diagnosis, judgment transfer and prognosis evaluation of gastric cancer, especially the value of combined with a number of indicators is greater. Therefore, finding an early diagnosis and judging the ideal tumor logo combination of the early diagnosis and judgment of the prognosis is important. This article reviews the biological characteristics of Survivin and its research progress in gastric cancer, so as to provide theoretical basis for the diagnosis of gastric cancer and new ideas for the successful prevention and treatment of tumors.
    },
     year = {2024}
    }
    

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    T1  - Research Progress of Apoptosis Inhibitory Protein Survivin in Gastric Cancer
    AU  - Hou Jianzhang
    AU  - Zhang Shuli
    AU  - Li Jiyong
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    AU  - Hou Zhenjiang
    Y1  - 2024/03/25
    PY  - 2024
    N1  - https://doi.org/10.11648/j.ajhr.20241202.12
    DO  - 10.11648/j.ajhr.20241202.12
    T2  - American Journal of Health Research
    JF  - American Journal of Health Research
    JO  - American Journal of Health Research
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    EP  - 36
    PB  - Science Publishing Group
    SN  - 2330-8796
    UR  - https://doi.org/10.11648/j.ajhr.20241202.12
    AB  - Survivin is an important member of the apoptosis inhibitory protein family, which plays an important role in suppressing apoptosis, promoting proliferation and vascular formation. The occurrence and development of tumors are related to apoptosis and imbalance of proliferation. Gastric cancer is the most common malignant tumor in the digestive system. Due to the inadequate symptoms of early symptoms, most of them have entered the middle and late stages during diagnosis. It is easy to relapse and metastasize. The mortality rate is high, which seriously endangers human health. Research have found that Survivin expresses high in gastric cancer tissue, participating in the proliferation of tumor cells, inhibiting apoptosis and the formation of blood vessels, and is of great significance to the diagnosis, judgment transfer and prognosis evaluation of gastric cancer, especially the value of combined with a number of indicators is greater. Therefore, finding an early diagnosis and judging the ideal tumor logo combination of the early diagnosis and judgment of the prognosis is important. This article reviews the biological characteristics of Survivin and its research progress in gastric cancer, so as to provide theoretical basis for the diagnosis of gastric cancer and new ideas for the successful prevention and treatment of tumors.
    
    VL  - 12
    IS  - 2
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Author Information
  • Hepatobiliary Pancreatic (Minimally Invasive) Surgery, Cancer District of Cangzhou People's Hospital, Cangzhou, China

  • Hepatobiliary Pancreatic (Minimally Invasive) Surgery, Cancer District of Cangzhou People's Hospital, Cangzhou, China

  • Department of Medical Technology, Cangzhou Medical College, Cangzhou, China

  • Department of Medical Technology, Cangzhou Medical College, Cangzhou, China

  • Department of Medical Technology, Cangzhou Medical College, Cangzhou, China

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