Background: Hypertrophic scars are fibroproliferative lesions caused by abnormal wound healing and involve complex vascular and fibrotic processes. Current treatments often yield variable outcomes, supporting interest in multimodal approaches that target different components of scar pathology. Case Presentation: A 30-year-old male presented with a traumatic hypertrophic scar on the dorsum of the right hand following a degloving/avulsion injury involving deep dermal and subcutaneous tissue. After immediate surgical debridement, the patient received two months of biweekly polydeoxyribonucleotide (PDRN) injections and regenerative laser therapy without noticeable improvement. After an 8-month treatment free interval, the patient underwent six biweekly sessions combining vascular laser, fractional ablative laser, radiofrequency microneedling, and topical exosome-based therapy, alternating with vascular laser monotherapy. Outcomes were assessed using the Vancouver Scar Scale (VSS) and Global Aesthetic Improvement Scale (GAIS). Results: Vascularity, pliability, scar height, and overall appearance improved progressively. The VSS score decreased from 10 at baseline to 4 after six sessions, with a transition from a purple, firm, raised scar to a pink, supple, and flat lesion. GAIS improved from 3 after the second session to 1 after the fifth and sixth sessions. Residual hyperpigmentation persisted. No treatment-related adverse events were observed. Conclusion: This case highlights the potential of a minimally invasive, multimodal approach to improve vascularity and remodeling in traumatic hypertrophic scars. Further studies are required to validate these findings.
| Published in | International Journal of Clinical Dermatology (Volume 9, Issue 2) |
| DOI | 10.11648/j.ijcd.20260902.15 |
| Page(s) | 140-144 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2026. Published by Science Publishing Group |
Energy-based Therapy, Exosome Therapy, Hypertrophic Scar, Multimodal Treatment, Radiofrequency Microneedling, Regenerative Medicine, Scar Remodeling, Traumatic Scar
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APA Style
Bock, M. (2026). Minimally Invasive Multimodal Treatment of a Traumatic Hypertrophic Scar Using Energy-Based and Regenerative Therapies: A Case Report. International Journal of Clinical Dermatology, 9(2), 140-144. https://doi.org/10.11648/j.ijcd.20260902.15
ACS Style
Bock, M. Minimally Invasive Multimodal Treatment of a Traumatic Hypertrophic Scar Using Energy-Based and Regenerative Therapies: A Case Report. Int. J. Clin. Dermatol. 2026, 9(2), 140-144. doi: 10.11648/j.ijcd.20260902.15
AMA Style
Bock M. Minimally Invasive Multimodal Treatment of a Traumatic Hypertrophic Scar Using Energy-Based and Regenerative Therapies: A Case Report. Int J Clin Dermatol. 2026;9(2):140-144. doi: 10.11648/j.ijcd.20260902.15
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author = {Minsung Bock},
title = {Minimally Invasive Multimodal Treatment of a Traumatic Hypertrophic Scar Using Energy-Based and Regenerative Therapies: A Case Report},
journal = {International Journal of Clinical Dermatology},
volume = {9},
number = {2},
pages = {140-144},
doi = {10.11648/j.ijcd.20260902.15},
url = {https://doi.org/10.11648/j.ijcd.20260902.15},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcd.20260902.15},
abstract = {Background: Hypertrophic scars are fibroproliferative lesions caused by abnormal wound healing and involve complex vascular and fibrotic processes. Current treatments often yield variable outcomes, supporting interest in multimodal approaches that target different components of scar pathology. Case Presentation: A 30-year-old male presented with a traumatic hypertrophic scar on the dorsum of the right hand following a degloving/avulsion injury involving deep dermal and subcutaneous tissue. After immediate surgical debridement, the patient received two months of biweekly polydeoxyribonucleotide (PDRN) injections and regenerative laser therapy without noticeable improvement. After an 8-month treatment free interval, the patient underwent six biweekly sessions combining vascular laser, fractional ablative laser, radiofrequency microneedling, and topical exosome-based therapy, alternating with vascular laser monotherapy. Outcomes were assessed using the Vancouver Scar Scale (VSS) and Global Aesthetic Improvement Scale (GAIS). Results: Vascularity, pliability, scar height, and overall appearance improved progressively. The VSS score decreased from 10 at baseline to 4 after six sessions, with a transition from a purple, firm, raised scar to a pink, supple, and flat lesion. GAIS improved from 3 after the second session to 1 after the fifth and sixth sessions. Residual hyperpigmentation persisted. No treatment-related adverse events were observed. Conclusion: This case highlights the potential of a minimally invasive, multimodal approach to improve vascularity and remodeling in traumatic hypertrophic scars. Further studies are required to validate these findings.},
year = {2026}
}
TY - JOUR T1 - Minimally Invasive Multimodal Treatment of a Traumatic Hypertrophic Scar Using Energy-Based and Regenerative Therapies: A Case Report AU - Minsung Bock Y1 - 2026/10/28 PY - 2026 N1 - https://doi.org/10.11648/j.ijcd.20260902.15 DO - 10.11648/j.ijcd.20260902.15 T2 - International Journal of Clinical Dermatology JF - International Journal of Clinical Dermatology JO - International Journal of Clinical Dermatology SP - 140 EP - 144 PB - Science Publishing Group SN - 2995-1305 UR - https://doi.org/10.11648/j.ijcd.20260902.15 AB - Background: Hypertrophic scars are fibroproliferative lesions caused by abnormal wound healing and involve complex vascular and fibrotic processes. Current treatments often yield variable outcomes, supporting interest in multimodal approaches that target different components of scar pathology. Case Presentation: A 30-year-old male presented with a traumatic hypertrophic scar on the dorsum of the right hand following a degloving/avulsion injury involving deep dermal and subcutaneous tissue. After immediate surgical debridement, the patient received two months of biweekly polydeoxyribonucleotide (PDRN) injections and regenerative laser therapy without noticeable improvement. After an 8-month treatment free interval, the patient underwent six biweekly sessions combining vascular laser, fractional ablative laser, radiofrequency microneedling, and topical exosome-based therapy, alternating with vascular laser monotherapy. Outcomes were assessed using the Vancouver Scar Scale (VSS) and Global Aesthetic Improvement Scale (GAIS). Results: Vascularity, pliability, scar height, and overall appearance improved progressively. The VSS score decreased from 10 at baseline to 4 after six sessions, with a transition from a purple, firm, raised scar to a pink, supple, and flat lesion. GAIS improved from 3 after the second session to 1 after the fifth and sixth sessions. Residual hyperpigmentation persisted. No treatment-related adverse events were observed. Conclusion: This case highlights the potential of a minimally invasive, multimodal approach to improve vascularity and remodeling in traumatic hypertrophic scars. Further studies are required to validate these findings. VL - 9 IS - 2 ER -
Department of Translational Medicine, Graduate School of CHA University, Pocheon-si, Republic of Korea
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