Background: Small intestinal bacterial overgrowth (SIBO) is a condition often associated with irritable bowel syndrome (IBS), particularly IBS-D (diarrhea-predominant) and IBS-M (mixed-type). The relationship between SIBO and IBS subtypes remains poorly understood, despite its potential impact on treatment and symptom management. Methods: This observational cross-sectional study was conducted at the Department of Gastroenterology, Dhaka Medical College Hospital, from September 2018 to August 2019. A total of 104 adult patients diagnosed with IBS based on Rome IV criteria were enrolled. Duodenal aspirates were collected during upper gastrointestinal endoscopy, and SIBO was diagnosed using quantitative aerobic culture on blood agar and MacConkey agar plates, with ≥105 CFU/mL considered diagnostic. Demographic and clinical data were analyzed using SPSS software. Results: Of the 104 participants, 36.5% tested positive for SIBO. Among IBS-D patients, 53.3% were SIBO-positive, while only 13.7% of IBS-M patients showed positive results. The majority of isolates in the SIBO-positive group were Pseudomonas (78.9%), followed by E. coli (21.1%). A significant correlation was observed between SIBO and IBS-D, with higher colony counts in the SIBO-positive group. Conclusion: The study highlights a higher frequency of SIBO in IBS-D compared to IBS-M. Pseudomonas was the predominant bacterium isolated in patients with SIBO. These findings suggest the need for targeted management of SIBO in IBS-D patients.
| Published in | International Journal of Gastroenterology (Volume 9, Issue 1) |
| DOI | 10.11648/j.ijg.20250901.15 |
| Page(s) | 32-36 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2025. Published by Science Publishing Group |
Small Intestinal Bacterial Overgrowth, IBS-D, IBS-M, Duodenal Aspirate, Pseudomonas, Microbiology
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APA Style
Alam, M. J., Akter, M., Islam, M. S., Ahmed, F. (2025). Frequency and Bacterial Profile of Small Intestinal Bacterial Overgrowth in Patients with IBS D and IBS M in an Academic Hospital. International Journal of Gastroenterology, 9(1), 32-36. https://doi.org/10.11648/j.ijg.20250901.15
ACS Style
Alam, M. J.; Akter, M.; Islam, M. S.; Ahmed, F. Frequency and Bacterial Profile of Small Intestinal Bacterial Overgrowth in Patients with IBS D and IBS M in an Academic Hospital. Int. J. Gastroenterol. 2025, 9(1), 32-36. doi: 10.11648/j.ijg.20250901.15
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Download@article{10.11648/j.ijg.20250901.15,
author = {Mohammad Jane Alam and Mahfuza Akter and Mohammad Shohidul Islam and Faruque Ahmed},
title = {Frequency and Bacterial Profile of Small Intestinal Bacterial Overgrowth in Patients with IBS D and IBS M in an Academic Hospital
},
journal = {International Journal of Gastroenterology},
volume = {9},
number = {1},
pages = {32-36},
doi = {10.11648/j.ijg.20250901.15},
url = {https://doi.org/10.11648/j.ijg.20250901.15},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijg.20250901.15},
abstract = {Background: Small intestinal bacterial overgrowth (SIBO) is a condition often associated with irritable bowel syndrome (IBS), particularly IBS-D (diarrhea-predominant) and IBS-M (mixed-type). The relationship between SIBO and IBS subtypes remains poorly understood, despite its potential impact on treatment and symptom management. Methods: This observational cross-sectional study was conducted at the Department of Gastroenterology, Dhaka Medical College Hospital, from September 2018 to August 2019. A total of 104 adult patients diagnosed with IBS based on Rome IV criteria were enrolled. Duodenal aspirates were collected during upper gastrointestinal endoscopy, and SIBO was diagnosed using quantitative aerobic culture on blood agar and MacConkey agar plates, with ≥105 CFU/mL considered diagnostic. Demographic and clinical data were analyzed using SPSS software. Results: Of the 104 participants, 36.5% tested positive for SIBO. Among IBS-D patients, 53.3% were SIBO-positive, while only 13.7% of IBS-M patients showed positive results. The majority of isolates in the SIBO-positive group were Pseudomonas (78.9%), followed by E. coli (21.1%). A significant correlation was observed between SIBO and IBS-D, with higher colony counts in the SIBO-positive group. Conclusion: The study highlights a higher frequency of SIBO in IBS-D compared to IBS-M. Pseudomonas was the predominant bacterium isolated in patients with SIBO. These findings suggest the need for targeted management of SIBO in IBS-D patients.
},
year = {2025}
}
TY - JOUR T1 - Frequency and Bacterial Profile of Small Intestinal Bacterial Overgrowth in Patients with IBS D and IBS M in an Academic Hospital AU - Mohammad Jane Alam AU - Mahfuza Akter AU - Mohammad Shohidul Islam AU - Faruque Ahmed Y1 - 2025/05/19 PY - 2025 N1 - https://doi.org/10.11648/j.ijg.20250901.15 DO - 10.11648/j.ijg.20250901.15 T2 - International Journal of Gastroenterology JF - International Journal of Gastroenterology JO - International Journal of Gastroenterology SP - 32 EP - 36 PB - Science Publishing Group SN - 2640-169X UR - https://doi.org/10.11648/j.ijg.20250901.15 AB - Background: Small intestinal bacterial overgrowth (SIBO) is a condition often associated with irritable bowel syndrome (IBS), particularly IBS-D (diarrhea-predominant) and IBS-M (mixed-type). The relationship between SIBO and IBS subtypes remains poorly understood, despite its potential impact on treatment and symptom management. Methods: This observational cross-sectional study was conducted at the Department of Gastroenterology, Dhaka Medical College Hospital, from September 2018 to August 2019. A total of 104 adult patients diagnosed with IBS based on Rome IV criteria were enrolled. Duodenal aspirates were collected during upper gastrointestinal endoscopy, and SIBO was diagnosed using quantitative aerobic culture on blood agar and MacConkey agar plates, with ≥105 CFU/mL considered diagnostic. Demographic and clinical data were analyzed using SPSS software. Results: Of the 104 participants, 36.5% tested positive for SIBO. Among IBS-D patients, 53.3% were SIBO-positive, while only 13.7% of IBS-M patients showed positive results. The majority of isolates in the SIBO-positive group were Pseudomonas (78.9%), followed by E. coli (21.1%). A significant correlation was observed between SIBO and IBS-D, with higher colony counts in the SIBO-positive group. Conclusion: The study highlights a higher frequency of SIBO in IBS-D compared to IBS-M. Pseudomonas was the predominant bacterium isolated in patients with SIBO. These findings suggest the need for targeted management of SIBO in IBS-D patients. VL - 9 IS - 1 ER -
Department of Medical Gastroenterology, National Gastroliver Institute and Hospital, Mohakhali, Dhaka, Bangladesh
Department of Medical Gastroenterology, National Gastroliver Institute and Hospital, Mohakhali, Dhaka, Bangladesh
Department of Medical Gastroenterology, National Gastroliver Institute and Hospital, Mohakhali, Dhaka, Bangladesh
Department of Medical Gastroenterology, National Gastroliver Institute and Hospital, Mohakhali, Dhaka, Bangladesh
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