Phytochemical Study and Characterization of the Fixed Oil of Melothria Maderaspatana Fruit

Wade Moustapha; Thiam Abdoulaye; Mbow Bedie; Sy Papa Biram; Diop Serigne Mbacke; Diop Awa; Fall Alioune; Sene Madieye; Fofana Mouhamadou

doi:doi:10.11648/j.ijpc.20261201.11

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Phytochemical Study and Characterization of the Fixed Oil of Melothria Maderaspatana Fruit

Wade Moustapha^*

, Thiam Abdoulaye, Mbow Bedie, Sy Papa Biram, Diop Serigne Mbacke, Diop Awa, Fall Alioune, Sene Madieye, Fofana Mouhamadou

Published in International Journal of Pharmacy and Chemistry (Volume 12, Issue 1)

Received: 24 January 2026 Accepted: 4 February 2026 Published: 21 February 2026

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Abstract

This study aims to evaluate the phytochemical composition of Melothria maderaspatana (L.) Cogn. fruits, a plant recognized in African and Indian pharmacopeias, and to physicochemical characterize its fixed oil extract, in order to enhance its potential in phytomedicine. Fruits harvested in Taïba Ndiaye (Senegal) in December 2021 underwent qualitative phytochemical screening on hexane, ethyl acetate, methanolic, and aqueous extracts, followed by Soxhlet oil extraction (yield: 7.98%). Detected secondary metabolites include polyphenols (except hexane extract), flavonoids (aqueous extract), alkaloids (hexane and aqueous extracts), sterols/polyterpenes (except aqueous extract), leucoanthocyanins (except hexane extract), coumarins (hexane/ethyl acetate extracts), and gallic tannins (aqueous extract); saponins, mucilages, and catecholic tannins were absent. Oil characterization according to AFNOR standards reveals: iodine value (II) = 4.8 ± 0.07 g I₂/100 g, acid value (IA) = 1.0 ± 0.1 mg KOH/g, saponification value (IS) = 145.8 ± 0.05 mg KOH/g, peroxide value (IP) = 8.0 ± 0.3 µg O₂/g, and ester value (IE) = 144.8 ± 0.05 mg KOH/g. These results indicate a non-drying oil with low unsaturation, oxidation stability, and low free fatty acid content, highlighting the potential of M. maderaspatana as a source of lipids and bioactive compounds for nutraceutical and therapeutic applications, warranting complementary fatty acid analysis and toxicological evaluation.

Published in	International Journal of Pharmacy and Chemistry (Volume 12, Issue 1)
DOI	10.11648/j.ijpc.20261201.11
Page(s)	1-10
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2026. Published by Science Publishing Group

Keywords

Melothria Maderaspatana, Phytochemical Study, Fixed Oil

References

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APA Style

Moustapha, W., Abdoulaye, T., Bedie, M., Biram, S. P., Mbacke, D. S., et al. (2026). Phytochemical Study and Characterization of the Fixed Oil of Melothria Maderaspatana Fruit. International Journal of Pharmacy and Chemistry, 12(1), 1-10. https://doi.org/10.11648/j.ijpc.20261201.11

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ACS Style

Moustapha, W.; Abdoulaye, T.; Bedie, M.; Biram, S. P.; Mbacke, D. S., et al. Phytochemical Study and Characterization of the Fixed Oil of Melothria Maderaspatana Fruit. Int. J. Pharm. Chem. 2026, 12(1), 1-10. doi: 10.11648/j.ijpc.20261201.11

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AMA Style

Moustapha W, Abdoulaye T, Bedie M, Biram SP, Mbacke DS, et al. Phytochemical Study and Characterization of the Fixed Oil of Melothria Maderaspatana Fruit. Int J Pharm Chem. 2026;12(1):1-10. doi: 10.11648/j.ijpc.20261201.11

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@article{10.11648/j.ijpc.20261201.11,
  author = {Wade Moustapha and Thiam Abdoulaye and Mbow Bedie and Sy Papa Biram and Diop Serigne Mbacke and Diop Awa and Fall Alioune and Sene Madieye and Fofana Mouhamadou},
  title = {Phytochemical Study and Characterization of the Fixed Oil of Melothria Maderaspatana Fruit},
  journal = {International Journal of Pharmacy and Chemistry},
  volume = {12},
  number = {1},
  pages = {1-10},
  doi = {10.11648/j.ijpc.20261201.11},
  url = {https://doi.org/10.11648/j.ijpc.20261201.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijpc.20261201.11},
  abstract = {This study aims to evaluate the phytochemical composition of Melothria maderaspatana (L.) Cogn. fruits, a plant recognized in African and Indian pharmacopeias, and to physicochemical characterize its fixed oil extract, in order to enhance its potential in phytomedicine. Fruits harvested in Taïba Ndiaye (Senegal) in December 2021 underwent qualitative phytochemical screening on hexane, ethyl acetate, methanolic, and aqueous extracts, followed by Soxhlet oil extraction (yield: 7.98%). Detected secondary metabolites include polyphenols (except hexane extract), flavonoids (aqueous extract), alkaloids (hexane and aqueous extracts), sterols/polyterpenes (except aqueous extract), leucoanthocyanins (except hexane extract), coumarins (hexane/ethyl acetate extracts), and gallic tannins (aqueous extract); saponins, mucilages, and catecholic tannins were absent. Oil characterization according to AFNOR standards reveals: iodine value (II) = 4.8 ± 0.07 g I₂/100 g, acid value (IA) = 1.0 ± 0.1 mg KOH/g, saponification value (IS) = 145.8 ± 0.05 mg KOH/g, peroxide value (IP) = 8.0 ± 0.3 µg O₂/g, and ester value (IE) = 144.8 ± 0.05 mg KOH/g. These results indicate a non-drying oil with low unsaturation, oxidation stability, and low free fatty acid content, highlighting the potential of M. maderaspatana as a source of lipids and bioactive compounds for nutraceutical and therapeutic applications, warranting complementary fatty acid analysis and toxicological evaluation.},
 year = {2026}
}

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TY  - JOUR
T1  - Phytochemical Study and Characterization of the Fixed Oil of Melothria Maderaspatana Fruit
AU  - Wade Moustapha
AU  - Thiam Abdoulaye
AU  - Mbow Bedie
AU  - Sy Papa Biram
AU  - Diop Serigne Mbacke
AU  - Diop Awa
AU  - Fall Alioune
AU  - Sene Madieye
AU  - Fofana Mouhamadou
Y1  - 2026/02/21
PY  - 2026
N1  - https://doi.org/10.11648/j.ijpc.20261201.11
DO  - 10.11648/j.ijpc.20261201.11
T2  - International Journal of Pharmacy and Chemistry
JF  - International Journal of Pharmacy and Chemistry
JO  - International Journal of Pharmacy and Chemistry
SP  - 1
EP  - 10
PB  - Science Publishing Group
SN  - 2575-5749
UR  - https://doi.org/10.11648/j.ijpc.20261201.11
AB  - This study aims to evaluate the phytochemical composition of Melothria maderaspatana (L.) Cogn. fruits, a plant recognized in African and Indian pharmacopeias, and to physicochemical characterize its fixed oil extract, in order to enhance its potential in phytomedicine. Fruits harvested in Taïba Ndiaye (Senegal) in December 2021 underwent qualitative phytochemical screening on hexane, ethyl acetate, methanolic, and aqueous extracts, followed by Soxhlet oil extraction (yield: 7.98%). Detected secondary metabolites include polyphenols (except hexane extract), flavonoids (aqueous extract), alkaloids (hexane and aqueous extracts), sterols/polyterpenes (except aqueous extract), leucoanthocyanins (except hexane extract), coumarins (hexane/ethyl acetate extracts), and gallic tannins (aqueous extract); saponins, mucilages, and catecholic tannins were absent. Oil characterization according to AFNOR standards reveals: iodine value (II) = 4.8 ± 0.07 g I₂/100 g, acid value (IA) = 1.0 ± 0.1 mg KOH/g, saponification value (IS) = 145.8 ± 0.05 mg KOH/g, peroxide value (IP) = 8.0 ± 0.3 µg O₂/g, and ester value (IE) = 144.8 ± 0.05 mg KOH/g. These results indicate a non-drying oil with low unsaturation, oxidation stability, and low free fatty acid content, highlighting the potential of M. maderaspatana as a source of lipids and bioactive compounds for nutraceutical and therapeutic applications, warranting complementary fatty acid analysis and toxicological evaluation.
VL  - 12
IS  - 1
ER  -

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Author Information

Wade Moustapha

Department of Chemistry, Cheikh Anta Diop University, Dakar, Senegal

Contact Email

http://orcid.org/0009-0006-9449-6650
Thiam Abdoulaye

Department of Chemistry, Cheikh Anta Diop University, Dakar, Senegal
Mbow Bedie

Department of Chemistry, Cheikh Anta Diop University, Dakar, Senegal
Sy Papa Biram

Department of Chemistry, Cheikh Anta Diop University, Dakar, Senegal
Diop Serigne Mbacke

Department of Chemistry, Institut de Technologie Alimentaire, Dakar, Senegal
Diop Awa

Department of Chemistry, Cheikh Anta Diop University, Dakar, Senegal
Fall Alioune

Department of Chemistry, Cheikh Anta Diop University, Dakar, Senegal
Sene Madieye

Department of Pharmacy, Cheikh Anta Diop University, Dakar, Senegal
Fofana Mouhamadou

Department of Chemistry, Cheikh Anta Diop University, Dakar, Senegal

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APA Style

Moustapha, W., Abdoulaye, T., Bedie, M., Biram, S. P., Mbacke, D. S., et al. (2026). Phytochemical Study and Characterization of the Fixed Oil of Melothria Maderaspatana Fruit. International Journal of Pharmacy and Chemistry, 12(1), 1-10. https://doi.org/10.11648/j.ijpc.20261201.11

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ACS Style

Moustapha, W.; Abdoulaye, T.; Bedie, M.; Biram, S. P.; Mbacke, D. S., et al. Phytochemical Study and Characterization of the Fixed Oil of Melothria Maderaspatana Fruit. Int. J. Pharm. Chem. 2026, 12(1), 1-10. doi: 10.11648/j.ijpc.20261201.11

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AMA Style

Moustapha W, Abdoulaye T, Bedie M, Biram SP, Mbacke DS, et al. Phytochemical Study and Characterization of the Fixed Oil of Melothria Maderaspatana Fruit. Int J Pharm Chem. 2026;12(1):1-10. doi: 10.11648/j.ijpc.20261201.11

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@article{10.11648/j.ijpc.20261201.11,
  author = {Wade Moustapha and Thiam Abdoulaye and Mbow Bedie and Sy Papa Biram and Diop Serigne Mbacke and Diop Awa and Fall Alioune and Sene Madieye and Fofana Mouhamadou},
  title = {Phytochemical Study and Characterization of the Fixed Oil of Melothria Maderaspatana Fruit},
  journal = {International Journal of Pharmacy and Chemistry},
  volume = {12},
  number = {1},
  pages = {1-10},
  doi = {10.11648/j.ijpc.20261201.11},
  url = {https://doi.org/10.11648/j.ijpc.20261201.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijpc.20261201.11},
  abstract = {This study aims to evaluate the phytochemical composition of Melothria maderaspatana (L.) Cogn. fruits, a plant recognized in African and Indian pharmacopeias, and to physicochemical characterize its fixed oil extract, in order to enhance its potential in phytomedicine. Fruits harvested in Taïba Ndiaye (Senegal) in December 2021 underwent qualitative phytochemical screening on hexane, ethyl acetate, methanolic, and aqueous extracts, followed by Soxhlet oil extraction (yield: 7.98%). Detected secondary metabolites include polyphenols (except hexane extract), flavonoids (aqueous extract), alkaloids (hexane and aqueous extracts), sterols/polyterpenes (except aqueous extract), leucoanthocyanins (except hexane extract), coumarins (hexane/ethyl acetate extracts), and gallic tannins (aqueous extract); saponins, mucilages, and catecholic tannins were absent. Oil characterization according to AFNOR standards reveals: iodine value (II) = 4.8 ± 0.07 g I₂/100 g, acid value (IA) = 1.0 ± 0.1 mg KOH/g, saponification value (IS) = 145.8 ± 0.05 mg KOH/g, peroxide value (IP) = 8.0 ± 0.3 µg O₂/g, and ester value (IE) = 144.8 ± 0.05 mg KOH/g. These results indicate a non-drying oil with low unsaturation, oxidation stability, and low free fatty acid content, highlighting the potential of M. maderaspatana as a source of lipids and bioactive compounds for nutraceutical and therapeutic applications, warranting complementary fatty acid analysis and toxicological evaluation.},
 year = {2026}
}

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TY  - JOUR
T1  - Phytochemical Study and Characterization of the Fixed Oil of Melothria Maderaspatana Fruit
AU  - Wade Moustapha
AU  - Thiam Abdoulaye
AU  - Mbow Bedie
AU  - Sy Papa Biram
AU  - Diop Serigne Mbacke
AU  - Diop Awa
AU  - Fall Alioune
AU  - Sene Madieye
AU  - Fofana Mouhamadou
Y1  - 2026/02/21
PY  - 2026
N1  - https://doi.org/10.11648/j.ijpc.20261201.11
DO  - 10.11648/j.ijpc.20261201.11
T2  - International Journal of Pharmacy and Chemistry
JF  - International Journal of Pharmacy and Chemistry
JO  - International Journal of Pharmacy and Chemistry
SP  - 1
EP  - 10
PB  - Science Publishing Group
SN  - 2575-5749
UR  - https://doi.org/10.11648/j.ijpc.20261201.11
AB  - This study aims to evaluate the phytochemical composition of Melothria maderaspatana (L.) Cogn. fruits, a plant recognized in African and Indian pharmacopeias, and to physicochemical characterize its fixed oil extract, in order to enhance its potential in phytomedicine. Fruits harvested in Taïba Ndiaye (Senegal) in December 2021 underwent qualitative phytochemical screening on hexane, ethyl acetate, methanolic, and aqueous extracts, followed by Soxhlet oil extraction (yield: 7.98%). Detected secondary metabolites include polyphenols (except hexane extract), flavonoids (aqueous extract), alkaloids (hexane and aqueous extracts), sterols/polyterpenes (except aqueous extract), leucoanthocyanins (except hexane extract), coumarins (hexane/ethyl acetate extracts), and gallic tannins (aqueous extract); saponins, mucilages, and catecholic tannins were absent. Oil characterization according to AFNOR standards reveals: iodine value (II) = 4.8 ± 0.07 g I₂/100 g, acid value (IA) = 1.0 ± 0.1 mg KOH/g, saponification value (IS) = 145.8 ± 0.05 mg KOH/g, peroxide value (IP) = 8.0 ± 0.3 µg O₂/g, and ester value (IE) = 144.8 ± 0.05 mg KOH/g. These results indicate a non-drying oil with low unsaturation, oxidation stability, and low free fatty acid content, highlighting the potential of M. maderaspatana as a source of lipids and bioactive compounds for nutraceutical and therapeutic applications, warranting complementary fatty acid analysis and toxicological evaluation.
VL  - 12
IS  - 1
ER  -

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