Chinese Expert Consensus on Percutaneous Balloon Compression for Trigeminal Neuralgia (2022) , International Journal of Pain Research, Science Publishing Group

Review Article |

| Peer-Reviewed

Chinese Expert Consensus on Percutaneous Balloon Compression for Trigeminal Neuralgia (2022)

Ren Yu'e

, Liu Xiaohui

, Cheng Zhixiang

, Fan Xiaochong

, Fan Bifa

, Huang Dong

, Hu Yongsheng

, Jiang Zongbin

, Luo Fang

, Ma Ke

, Qian Tao

, Sun Tao

, Sun Hongtao

, Yang Liqiang

, Yu Wenhua

, Zhong Jun

, Zhao Zongmao

, Zhou Huacheng

, Liu Guangzhao^*

Published in International Journal of Pain Research (Volume 1, Issue 4)

Received: 10 October 2025 Accepted: 22 October 2025 Published: 26 November 2025

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Abstract

Percutaneous balloon compression (PBC) is recognized as a simple, safe, and effective intervention for trigeminal neuralgia (TN) and has been widely adopted in clinical practice across China. However, variations in its application exist among different regions. To standardize procedural protocols and enhance clinical outcomes, a multidisciplinary panel of Chinese experts from pain medicine and neurosurgery collaboratively developed this clinical expert consensus. The consensus formulation involved a systematic literature review of major databases, including Wanfang and PubMed, among others, and focusing on high-quality evidence such as systematic reviews, meta-analyses, randomized controlled trials, expert consensus statements, and clinical guidelines. Using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) framework and structured consensus conference methods, the panel held iterative discussions and conducted voting sessions to finalize the recommendations. This document summarizes key aspects of PBC, including relevant anatomy, mechanisms of action, indications, contraindications, detailed operative techniques, and efficacy evaluation. It aims to serve as a practical reference for clinicians to standardize and optimize the use of PBC in the treatment of trigeminal neuralgia.

Published in	International Journal of Pain Research (Volume 1, Issue 4)
DOI	10.11648/j.ijpr.20250104.17
Page(s)	157-171
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2025. Published by Science Publishing Group

Keywords

Percutaneous Balloon Compression, Trigeminal Neuralgia, Pain, Expert Consensus

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Yu'e, R., Xiaohui, L., Zhixiang, C., Xiaochong, F., Bifa, F., et al. (2025). Chinese Expert Consensus on Percutaneous Balloon Compression for Trigeminal Neuralgia (2022). International Journal of Pain Research, 1(4), 157-171. https://doi.org/10.11648/j.ijpr.20250104.17

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ACS Style

Yu'e, R.; Xiaohui, L.; Zhixiang, C.; Xiaochong, F.; Bifa, F., et al. Chinese Expert Consensus on Percutaneous Balloon Compression for Trigeminal Neuralgia (2022). . 2025, 1(4), 157-171. doi: 10.11648/j.ijpr.20250104.17

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AMA Style

Yu'e R, Xiaohui L, Zhixiang C, Xiaochong F, Bifa F, et al. Chinese Expert Consensus on Percutaneous Balloon Compression for Trigeminal Neuralgia (2022). . 2025;1(4):157-171. doi: 10.11648/j.ijpr.20250104.17

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@article{10.11648/j.ijpr.20250104.17,
  author = {Ren Yu'e and Liu Xiaohui and Cheng Zhixiang and Fan Xiaochong and Fan Bifa and Huang Dong and Hu Yongsheng and Jiang Zongbin and Luo Fang and Ma Ke and Qian Tao and Sun Tao and Sun Hongtao and Yang Liqiang and Yu Wenhua and Zhong Jun and Zhao Zongmao and Zhou Huacheng and Liu Guangzhao},
  title = {Chinese Expert Consensus on Percutaneous Balloon Compression for Trigeminal Neuralgia (2022)
},
  journal = {International Journal of Pain Research},
  volume = {1},
  number = {4},
  pages = {157-171},
  doi = {10.11648/j.ijpr.20250104.17},
  url = {https://doi.org/10.11648/j.ijpr.20250104.17},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijpr.20250104.17},
  abstract = {Percutaneous balloon compression (PBC) is recognized as a simple, safe, and effective intervention for trigeminal neuralgia (TN) and has been widely adopted in clinical practice across China. However, variations in its application exist among different regions. To standardize procedural protocols and enhance clinical outcomes, a multidisciplinary panel of Chinese experts from pain medicine and neurosurgery collaboratively developed this clinical expert consensus. The consensus formulation involved a systematic literature review of major databases, including Wanfang and PubMed, among others, and focusing on high-quality evidence such as systematic reviews, meta-analyses, randomized controlled trials, expert consensus statements, and clinical guidelines. Using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) framework and structured consensus conference methods, the panel held iterative discussions and conducted voting sessions to finalize the recommendations. This document summarizes key aspects of PBC, including relevant anatomy, mechanisms of action, indications, contraindications, detailed operative techniques, and efficacy evaluation. It aims to serve as a practical reference for clinicians to standardize and optimize the use of PBC in the treatment of trigeminal neuralgia.},
 year = {2025}
}

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TY  - JOUR
T1  - Chinese Expert Consensus on Percutaneous Balloon Compression for Trigeminal Neuralgia (2022)

AU  - Ren Yu'e
AU  - Liu Xiaohui
AU  - Cheng Zhixiang
AU  - Fan Xiaochong
AU  - Fan Bifa
AU  - Huang Dong
AU  - Hu Yongsheng
AU  - Jiang Zongbin
AU  - Luo Fang
AU  - Ma Ke
AU  - Qian Tao
AU  - Sun Tao
AU  - Sun Hongtao
AU  - Yang Liqiang
AU  - Yu Wenhua
AU  - Zhong Jun
AU  - Zhao Zongmao
AU  - Zhou Huacheng
AU  - Liu Guangzhao
Y1  - 2025/11/26
PY  - 2025
N1  - https://doi.org/10.11648/j.ijpr.20250104.17
DO  - 10.11648/j.ijpr.20250104.17
T2  - International Journal of Pain Research
JF  - International Journal of Pain Research
JO  - International Journal of Pain Research
SP  - 157
EP  - 171
PB  - Science Publishing Group
UR  - https://doi.org/10.11648/j.ijpr.20250104.17
AB  - Percutaneous balloon compression (PBC) is recognized as a simple, safe, and effective intervention for trigeminal neuralgia (TN) and has been widely adopted in clinical practice across China. However, variations in its application exist among different regions. To standardize procedural protocols and enhance clinical outcomes, a multidisciplinary panel of Chinese experts from pain medicine and neurosurgery collaboratively developed this clinical expert consensus. The consensus formulation involved a systematic literature review of major databases, including Wanfang and PubMed, among others, and focusing on high-quality evidence such as systematic reviews, meta-analyses, randomized controlled trials, expert consensus statements, and clinical guidelines. Using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) framework and structured consensus conference methods, the panel held iterative discussions and conducted voting sessions to finalize the recommendations. This document summarizes key aspects of PBC, including relevant anatomy, mechanisms of action, indications, contraindications, detailed operative techniques, and efficacy evaluation. It aims to serve as a practical reference for clinicians to standardize and optimize the use of PBC in the treatment of trigeminal neuralgia.
VL  - 1
IS  - 4
ER  -

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Author Information

Ren Yu'e

Department of Painology, The Second Hospital of Hebei Medical University, Shijiazhuang, China

Contact Email

http://orcid.org/0009-0002-0741-3142
Liu Xiaohui

Department of Painology, The Second Hospital of Hebei Medical University, Shijiazhuang, China

Contact Email

http://orcid.org/0009-0008-4327-5334
Cheng Zhixiang

Department of Painology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China

http://orcid.org/0000-0003-0867-685X
Fan Xiaochong

Department of Pain Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China

http://orcid.org/0000-0002-6640-2665
Fan Bifa

Department of Pain Medicine, China Japan Friendship Hospital, Beijing, China

http://orcid.org/0000-0001-7340-4039
Huang Dong

Department of Pain Medicine, The Third Xiangya Hospital of Central South University, Changsha, China

http://orcid.org/0000-0002-4880-2438
Hu Yongsheng

Department of Functional Neurosurgery, Xuanwu Hospital Capital Medical University, Beijing, China

http://orcid.org/0000-0001-9782-584X
Jiang Zongbin

Department of Pain Medicine, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China

http://orcid.org/0009-0001-2926-630X
Luo Fang

Department of Pain Medicine, Beijing Tiantan Hospital, Beijing, China

http://orcid.org/0000-0002-3584-0355
Ma Ke

Department of Pain Medicine, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China

http://orcid.org/0000-0002-5603-9321
Qian Tao

Department of Neurosurgery, Hebei General Hospital, Shijiazhuang, China

http://orcid.org/0009-0003-6062-2135
Sun Tao

Department of Pain Medicine, Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China

http://orcid.org/0000-0003-0880-6394
Sun Hongtao

Department of Neurosurgery, Chinese People's Armed Police Force Characteristic Medical Center, Tianjin, China

http://orcid.org/0000-0001-8621-3215
Yang Liqiang

Department of Pain Medicine, Xuanwu Hospital Capital Medical University, Beijing, China

http://orcid.org/0000-0002-1940-9979
Yu Wenhua

Department of Neurosurgery, First People's Hospital of Hangzhou, Hangzhou, China

http://orcid.org/0009-0004-1627-437X
Zhong Jun

Department of Neurosurgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China

http://orcid.org/0000-0003-4349-2431
Zhao Zongmao

Department of Neurosurgery, The Second Hospital of Hebei Medical University, Shijiazhuang, China

http://orcid.org/0000-0002-3753-3949
Zhou Huacheng

Department of Pain Medicine, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China

http://orcid.org/0000-0001-6506-5495
Liu Guangzhao

Department of Painology, The Second Hospital of Hebei Medical University, Shijiazhuang, China

Contact Email

http://orcid.org/0000-0001-7415-6292

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APA Style

Yu'e, R., Xiaohui, L., Zhixiang, C., Xiaochong, F., Bifa, F., et al. (2025). Chinese Expert Consensus on Percutaneous Balloon Compression for Trigeminal Neuralgia (2022). International Journal of Pain Research, 1(4), 157-171. https://doi.org/10.11648/j.ijpr.20250104.17

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ACS Style

Yu'e, R.; Xiaohui, L.; Zhixiang, C.; Xiaochong, F.; Bifa, F., et al. Chinese Expert Consensus on Percutaneous Balloon Compression for Trigeminal Neuralgia (2022). . 2025, 1(4), 157-171. doi: 10.11648/j.ijpr.20250104.17

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AMA Style

Yu'e R, Xiaohui L, Zhixiang C, Xiaochong F, Bifa F, et al. Chinese Expert Consensus on Percutaneous Balloon Compression for Trigeminal Neuralgia (2022). . 2025;1(4):157-171. doi: 10.11648/j.ijpr.20250104.17

Copy | Download

@article{10.11648/j.ijpr.20250104.17,
  author = {Ren Yu'e and Liu Xiaohui and Cheng Zhixiang and Fan Xiaochong and Fan Bifa and Huang Dong and Hu Yongsheng and Jiang Zongbin and Luo Fang and Ma Ke and Qian Tao and Sun Tao and Sun Hongtao and Yang Liqiang and Yu Wenhua and Zhong Jun and Zhao Zongmao and Zhou Huacheng and Liu Guangzhao},
  title = {Chinese Expert Consensus on Percutaneous Balloon Compression for Trigeminal Neuralgia (2022)
},
  journal = {International Journal of Pain Research},
  volume = {1},
  number = {4},
  pages = {157-171},
  doi = {10.11648/j.ijpr.20250104.17},
  url = {https://doi.org/10.11648/j.ijpr.20250104.17},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijpr.20250104.17},
  abstract = {Percutaneous balloon compression (PBC) is recognized as a simple, safe, and effective intervention for trigeminal neuralgia (TN) and has been widely adopted in clinical practice across China. However, variations in its application exist among different regions. To standardize procedural protocols and enhance clinical outcomes, a multidisciplinary panel of Chinese experts from pain medicine and neurosurgery collaboratively developed this clinical expert consensus. The consensus formulation involved a systematic literature review of major databases, including Wanfang and PubMed, among others, and focusing on high-quality evidence such as systematic reviews, meta-analyses, randomized controlled trials, expert consensus statements, and clinical guidelines. Using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) framework and structured consensus conference methods, the panel held iterative discussions and conducted voting sessions to finalize the recommendations. This document summarizes key aspects of PBC, including relevant anatomy, mechanisms of action, indications, contraindications, detailed operative techniques, and efficacy evaluation. It aims to serve as a practical reference for clinicians to standardize and optimize the use of PBC in the treatment of trigeminal neuralgia.},
 year = {2025}
}

Copy | Download

TY  - JOUR
T1  - Chinese Expert Consensus on Percutaneous Balloon Compression for Trigeminal Neuralgia (2022)

AU  - Ren Yu'e
AU  - Liu Xiaohui
AU  - Cheng Zhixiang
AU  - Fan Xiaochong
AU  - Fan Bifa
AU  - Huang Dong
AU  - Hu Yongsheng
AU  - Jiang Zongbin
AU  - Luo Fang
AU  - Ma Ke
AU  - Qian Tao
AU  - Sun Tao
AU  - Sun Hongtao
AU  - Yang Liqiang
AU  - Yu Wenhua
AU  - Zhong Jun
AU  - Zhao Zongmao
AU  - Zhou Huacheng
AU  - Liu Guangzhao
Y1  - 2025/11/26
PY  - 2025
N1  - https://doi.org/10.11648/j.ijpr.20250104.17
DO  - 10.11648/j.ijpr.20250104.17
T2  - International Journal of Pain Research
JF  - International Journal of Pain Research
JO  - International Journal of Pain Research
SP  - 157
EP  - 171
PB  - Science Publishing Group
UR  - https://doi.org/10.11648/j.ijpr.20250104.17
AB  - Percutaneous balloon compression (PBC) is recognized as a simple, safe, and effective intervention for trigeminal neuralgia (TN) and has been widely adopted in clinical practice across China. However, variations in its application exist among different regions. To standardize procedural protocols and enhance clinical outcomes, a multidisciplinary panel of Chinese experts from pain medicine and neurosurgery collaboratively developed this clinical expert consensus. The consensus formulation involved a systematic literature review of major databases, including Wanfang and PubMed, among others, and focusing on high-quality evidence such as systematic reviews, meta-analyses, randomized controlled trials, expert consensus statements, and clinical guidelines. Using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) framework and structured consensus conference methods, the panel held iterative discussions and conducted voting sessions to finalize the recommendations. This document summarizes key aspects of PBC, including relevant anatomy, mechanisms of action, indications, contraindications, detailed operative techniques, and efficacy evaluation. It aims to serve as a practical reference for clinicians to standardize and optimize the use of PBC in the treatment of trigeminal neuralgia.
VL  - 1
IS  - 4
ER  -

Copy | Download