American Journal of Biomedical and Life Sciences

Submit a Manuscript

Publishing with us to make your research visible to the widest possible audience.

Propose a Special Issue

Building a community of authors and readers to discuss the latest research and develop new ideas.

Antimicrobial and Phytochemical Screening of Icacina Trichantha

Ethanol and water extracts of Icacina trichantha leaves were screened for their phytochemicals and antimicrobial activity against Escherichia coli, Staphylococcus aureus, streptococcus spp, Candida albicans and Klebsiella pneumonia. The result indicated that alkaloids, tannins, saponins, and phenols were present in the plant part. Both the ethanol extract and the water extract were active against all the microorganisms. The ethanol extract was more active than the water extract. This attest to the fact that Icacina trichantha leaves contains bioactive compounds of potentially therapeutic significance and thus could be a promissory candidate for drug development and validates folkloric claim by the traditional healers.

Icacina Trichantha, Ethanol, Extracts, Phytochemicals, Microorganisms, Drugs

Mohammed Hassan Shagal, Dimas Kubmarawa. (2013). Antimicrobial and Phytochemical Screening of Icacina Trichantha. American Journal of Biomedical and Life Sciences, 1(2), 37-40.

1. Akubue PI. Nigerian Medicinal Plants.Pharmacology and Toxicology. In: The State of Medicinal Plant Research in Nigeria (Edited by Abayomi, Sofowora) 1990; pp.53-54.
2. Oliver-Bever B. Medicinal Plants in Tropical West Africa. Cambridge University Press 1986; pp.940
3. Swain T. Plants in the Development of Modern Medicine Harvard University Press, Cambridge 1972; pp. 125 -129
4. El-Sayed SA, Salih AB, Mohamed MS, Mortada ME and Eman AE.Phytochemical Studies and Evaluation of Antioxidant, Anticancer and Antimicrobial Properties of Conocarpus erectus L. Growing in Taif, Saudi Arabia. European Journal of Medicinal Plants 2012; 2(2): 93-112
5. Ncube NS, Afolayan AJ, Okoh AI. Assessment techniques of antimicrobialproperties of natural compounds of plant origin: current methods and future trends.Afri J Biotechnol 2008; 7: 1797-1806.
6. NirmalaMJ, Samundeeswari A, Sankar PD. Natural plant resources in anticancertherapy-A review. Res Plant Biol 2011; 1: 1-14
7. Kviecinski MR, Felipe KB, Schoenfelder T, De Lemos LP, Rossi, MH, GonçalezE(2008). Study of the antitumor potential of Bidenspilosa(Asteraceae) used inBrazilian folk medicine. J Ethnopharm 2008; 117: 69–75.
8. Newman DJ, Cragg GM, Snader KM (2003). Natural products as sources of new drugsover the period 1981–2002. J Nat Prod 2003; 66: 1022-1037.
9. Verpoorte R.Pharmacognosy in the new millennium: lead finding andbiotechnology. J Pharm Pharmacol 2000; 52: 253-262.
10. Goodman J, Walsh V. The Story of Taxol.Cambridge University Press: New York 2001; pp 123-143
11. Klayman DL.Artemisia annua: from weed to respectable antimalarial plant. In: Kinghorn, A.D., Belandrin, M.F. (Eds.), Human Medicinal Agents fromPlants. American Chemical Society Series, Washington, DC 1993; pp.242-255
12. Carney JR, Krenisky JM, Williamson RT, Luo J, Carlson TJ, Hsu VL, MoswaJL. Maprouneacin, a new daphnanediterpenoid with potent anti-hyperglycemicactivity from Maprouneaafricana. J Nat Prod 1999; 62, 345–347.
13. Burkill, HM. Useful Plants of West Tropical Africa, 2nd, Vol. 1 Royal Botanical Garden, knew, 1985; pp. 88-91.
14. Mann A, Yahaya Y, Banso A, John F. Phytochemical and antimicrobial activity of Terminaliaavicennioides extracts against some bacteria pathogens associated with patients suffering from complicated respiratory tract diseases. J Med Plants Res 2008; 2(5): 94-97.
15. Harbone JB. Phytochemical Methods. Chapman and Hall, London 1991; pp. 84, 126, 199.
16. Odebiyi A, Sofowora AE. Phytochemical screening of Nigerian Medicinal Plants Part III,Lloyida 1990; Pp. 234 – 246.
17. Fadeyi MG, Adeoye AC, Olowokodejo JD. Epidermal and Phytochemical Studies with genus of Boerhavia(nyetanginaceae) Crude Drug Res 1989; 29: 178 – 184.
18. Mackie R, McCartney C. Practical Medicinal Microbiology 3rd edition, Vol. 2 Churchill Livingstone (publishers), London and New York 1989; Pp. 100– 106,121, 141, 163-167, 303, 432-491
19. Timothy O, Idu M. Preliminary phytochemical and in vitro antimicrobial properties of aqueous and methanol extracts of Icacina trichanthaOliv. Leaf.Int J Med ArmPlants2011; 1(3): 184-188.