Journal of Diseases and Medicinal Plants

Volume 2, Issue 2, April 2016

  • MIF Proteins from Two Nematodes Recognize Sera of Onchocerciasis Patients and Stimulate Peripheral Blood Mononuclear Cells to Release TNF-α and iL-10 Cytokines

    Boursou Djafsia, Dieudonne Ndjonka, Irene Ajonina-Ekoti

    Issue: Volume 2, Issue 2, April 2016
    Pages: 8-13
    Received: Mar. 31, 2016
    Accepted: Apr. 13, 2016
    Published: May 17, 2016
    Abstract: Onchocerciasis is a human filarial disease which leads to blindness in its ultimate phase. The immunopathology of the disease categorize patients into two types regarding the symptoms of the sickness: the hypo-reactive (generalized) and the hyper-reactive (sowda) types. In vitro, the humoral response by sera from the two categories of patient to re... Show More