Alzheimer’s disease is characterized by severe deficits in memory, cognition and motor functions, and the most prominent histopathological clues are the aggregation of amyloid-beta peptides and hyperphosphorylated tau tangles. In addition, other hypothesis explaining the pathogenesis of AD highlight neuroinflammation, an impairment in the calcium balance and energy metabolism, and vascular degeneration, but therapeutic strategies based on these current theories and ideas have not yielded any benefits during the last decades. This special issue aims to improve the dissemination of advanced research in the area of Alzheimer’s disease. Original research papers are solicited in any aspect of Alzheimer’s disease.

Aims and Scope:

1. Interactions between gut microbiota and Alzheimer’s disease
2. Explaining the pathogenesis of Alzheimer’s disease
3. Memory retrieval effects of engram cells in Alzheimer’s disease
4. Neuroinflammation
5. Protein clearance mechanisms
6. Antibody usage to prevent amyloid beta plaque accumulation
7. Amyloid Beta hypothesis
8. Acetylcholine hypothesis
9. Neurotransmitter systems affect memory and other cognitive functions
10. New animal models of Alzheimer’s disease
11. Animal models
12. The effect of selective serotonin receptor inhibitor on memory
13. Learning and memory formation
14. Memory retrieval
15. Calcium and energy metabolism
16. Vascular degeneration
17. New treatment approaches