Anemia, an unresolved health problem in Cuba, has been attributed to iron (Fe) deficiency. There is little information regarding the relationship between anemia, zinc (Zn) deficiency and the effect of inflammation on Fe and Zn deficiencies. It is intended to identify hematological manifestations of anemia, iron and zinc deficiency and its relationship with inflammation in women of reproductive age (WRA) from different provinces of Cuba. An exploratory cross-sectional study was carried out from 2016 to 2018. 654 apparently healthy women aged 18 to 40 years were selected from different provinces of Cuba through multistage cluster sampling. The following were measured: hemoglobin (Hb), ferritin, C-reactive proteins (CRP), alpha glycoprotein (AGP), serum Zn. Ferritin concentrations were adjusted for inflammation using Thurnham's correction factors. International cut-off points were used. The median age was 28 years. Of the women, 18.3% (116/633) had anemia and 18.3% (21/115) of them had Fe deficiency. Adjusting ferritin concentrations for inflammation, the proportion of anemic women with Fe deficiency increased to 22.6% (26/115), and Fe deficiency in the total sample varied from 7.5% (48/639) to 10.0%. (62/639). Serum Zn deficiency was high, 35.7% (234/654), 25.0% of women with Zn deficiency had anemia, with or without inflammation. 42.7% (273/641) women had inflammation. The results suggest an apparent association between anemia and Zn deficiency, a nutritional disorder little studied in Cuba. There is high concordance between the unadjusted and adjusted ferritin concentrations values for inflammation.
| Published in | Biomedical Sciences (Volume 8, Issue 2) |
| DOI | 10.11648/j.bs.20220802.13 |
| Page(s) | 63-67 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
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Copyright © The Author(s), 2024. Published by Science Publishing Group |
Anemia, Zinc Deficiency, Women, Ferritin, Cuba
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APA Style
Ana Maria Gomez-Alvarez, Gisela Maria Pita-Rodriguez, Carlos Garcia-Pino, Angel Mollineda-Trujillo, Jorge Bacallao-Gallestey, et al. (2022). Zinc Deficiency and Anemia in Women of Reproductive Age, Cuba. Biomedical Sciences, 8(2), 63-67. https://doi.org/10.11648/j.bs.20220802.13
ACS Style
Ana Maria Gomez-Alvarez; Gisela Maria Pita-Rodriguez; Carlos Garcia-Pino; Angel Mollineda-Trujillo; Jorge Bacallao-Gallestey, et al. Zinc Deficiency and Anemia in Women of Reproductive Age, Cuba. Biomed. Sci. 2022, 8(2), 63-67. doi: 10.11648/j.bs.20220802.13
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author = {Ana Maria Gomez-Alvarez and Gisela Maria Pita-Rodriguez and Carlos Garcia-Pino and Angel Mollineda-Trujillo and Jorge Bacallao-Gallestey and Lidia Leonor Cardella-Rosales and Lismery Valdes-Collazo},
title = {Zinc Deficiency and Anemia in Women of Reproductive Age, Cuba},
journal = {Biomedical Sciences},
volume = {8},
number = {2},
pages = {63-67},
doi = {10.11648/j.bs.20220802.13},
url = {https://doi.org/10.11648/j.bs.20220802.13},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.bs.20220802.13},
abstract = {Anemia, an unresolved health problem in Cuba, has been attributed to iron (Fe) deficiency. There is little information regarding the relationship between anemia, zinc (Zn) deficiency and the effect of inflammation on Fe and Zn deficiencies. It is intended to identify hematological manifestations of anemia, iron and zinc deficiency and its relationship with inflammation in women of reproductive age (WRA) from different provinces of Cuba. An exploratory cross-sectional study was carried out from 2016 to 2018. 654 apparently healthy women aged 18 to 40 years were selected from different provinces of Cuba through multistage cluster sampling. The following were measured: hemoglobin (Hb), ferritin, C-reactive proteins (CRP), alpha glycoprotein (AGP), serum Zn. Ferritin concentrations were adjusted for inflammation using Thurnham's correction factors. International cut-off points were used. The median age was 28 years. Of the women, 18.3% (116/633) had anemia and 18.3% (21/115) of them had Fe deficiency. Adjusting ferritin concentrations for inflammation, the proportion of anemic women with Fe deficiency increased to 22.6% (26/115), and Fe deficiency in the total sample varied from 7.5% (48/639) to 10.0%. (62/639). Serum Zn deficiency was high, 35.7% (234/654), 25.0% of women with Zn deficiency had anemia, with or without inflammation. 42.7% (273/641) women had inflammation. The results suggest an apparent association between anemia and Zn deficiency, a nutritional disorder little studied in Cuba. There is high concordance between the unadjusted and adjusted ferritin concentrations values for inflammation.},
year = {2022}
}
TY - JOUR T1 - Zinc Deficiency and Anemia in Women of Reproductive Age, Cuba AU - Ana Maria Gomez-Alvarez AU - Gisela Maria Pita-Rodriguez AU - Carlos Garcia-Pino AU - Angel Mollineda-Trujillo AU - Jorge Bacallao-Gallestey AU - Lidia Leonor Cardella-Rosales AU - Lismery Valdes-Collazo Y1 - 2022/06/09 PY - 2022 N1 - https://doi.org/10.11648/j.bs.20220802.13 DO - 10.11648/j.bs.20220802.13 T2 - Biomedical Sciences JF - Biomedical Sciences JO - Biomedical Sciences SP - 63 EP - 67 PB - Science Publishing Group SN - 2575-3932 UR - https://doi.org/10.11648/j.bs.20220802.13 AB - Anemia, an unresolved health problem in Cuba, has been attributed to iron (Fe) deficiency. There is little information regarding the relationship between anemia, zinc (Zn) deficiency and the effect of inflammation on Fe and Zn deficiencies. It is intended to identify hematological manifestations of anemia, iron and zinc deficiency and its relationship with inflammation in women of reproductive age (WRA) from different provinces of Cuba. An exploratory cross-sectional study was carried out from 2016 to 2018. 654 apparently healthy women aged 18 to 40 years were selected from different provinces of Cuba through multistage cluster sampling. The following were measured: hemoglobin (Hb), ferritin, C-reactive proteins (CRP), alpha glycoprotein (AGP), serum Zn. Ferritin concentrations were adjusted for inflammation using Thurnham's correction factors. International cut-off points were used. The median age was 28 years. Of the women, 18.3% (116/633) had anemia and 18.3% (21/115) of them had Fe deficiency. Adjusting ferritin concentrations for inflammation, the proportion of anemic women with Fe deficiency increased to 22.6% (26/115), and Fe deficiency in the total sample varied from 7.5% (48/639) to 10.0%. (62/639). Serum Zn deficiency was high, 35.7% (234/654), 25.0% of women with Zn deficiency had anemia, with or without inflammation. 42.7% (273/641) women had inflammation. The results suggest an apparent association between anemia and Zn deficiency, a nutritional disorder little studied in Cuba. There is high concordance between the unadjusted and adjusted ferritin concentrations values for inflammation. VL - 8 IS - 2 ER -
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