Journal of Drug Design and Medicinal Chemistry

Volume 3, Issue 4, August 2017

  • Docking and 3D-QSAR Studies on Some HCV NS5b Inhibitors

    Yasmine Shafike Moemen, Ahmed Mahmoud El-Nahas, Ahmed Helmy Ebraheem Hassan, Safwat Abdel-Azeim, Serry Atta Atta El-Bialy

    Issue: Volume 3, Issue 4, August 2017
    Pages: 49-59
    Received: 22 September 2016
    Accepted: 07 August 2017
    Published: 23 October 2017
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    Abstract: A theoretical study has been carried out to interpret and support experimental findings regarding inhibition mechanism of HCV NS5b. Twenty-five HCV NS5b inhibitors were docked by QM-Polarized Ligand Docking (QPLD) technique. The comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) methods were ... Show More
  • Phytochemical Constituents, Biological Activities, Therapeutic Potentials and Nutritional Values of Moringa oleifera (Zogale): A Review

    Adamu Idris Maizuwo, Aminu Sharif Hassan, Hassanah Momoh, Jabir Abdullahi Muhammad

    Issue: Volume 3, Issue 4, August 2017
    Pages: 60-66
    Received: 20 June 2017
    Accepted: 21 August 2017
    Published: 28 October 2017
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    Abstract: Moringa oleifera popularly known as Zogale in Northern Nigeria is one of the most widely distributed and cultivated plant species in the region. Moringa oleifera is a small or middle-sized tree, about 10m in height and is cultivated for different purposes such as vegetable, spice, medicine, for cooking and cosmetic oil. Different parts of this plan... Show More