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Palm Oil Consumption and Serum Lipid and Lipoprotein Profiles in Patients with Type 2 Diabetes in Abidjan

Received: 23 December 2025     Accepted: 9 January 2026     Published: 26 January 2026
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Abstract

Diabetes is a major public health problem, and dietary fat intake plays a significant role in its incidence and progression. The impact of palm oil consumption on lipid and lipoprotein profiles remains controversial, particularly among diabetic patients. This study aimed to assess the influence of palm oil consumption on serum lipid and lipoprotein profiles in patients with type 2 diabetes (T2D) in Abidjan. A cross-sectional study including diabetic patients categorised according to the frequency and form of palm oil consumption was conducted in which total cholesterol (TC), triglycerides (TG), HDL cholesterol (HDL-c), LDL cholesterol (LDL-c) and the atherogenic index were measured and compared between the different groups. The chi-squared test was used with a significance level of p value <0.05. No statistically significant differences were observed between frequent and occasional patient consumers in terms of total cholesterol (p=0.799), triglycerides (p=0.579), HDL-cholesterol (p=0.840), LDL-cholesterol (p=0.116) and atherogenic index (p=0.588). Similarly, the form of palm oil consumed did not significantly influence lipid and lipoprotein profiles. Palm oil consumption, regardless of frequency or form, does not significantly alter the lipid and lipoprotein profile of type 2 diabetic patients. These findings suggest that palm oil intake, within habitual dietary patterns, may not be a primary determinant of dyslipidemia in this population.

Published in Advances in Biochemistry (Volume 14, Issue 1)
DOI 10.11648/j.ab.20261401.11
Page(s) 1-8
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2026. Published by Science Publishing Group

Keywords

Type 2 Diabetes, Palm Oil, Total Cholesterol, Triglycerides, HDL Cholesterol, LDL Cholesterol, Atherogenic Index

1. Introduction
Type 2 diabetes (T2D) represents a major public health challenge, affecting an estimated 537 million people in 2021, with an alarming projection of 783 millions by 2045 . This chronic disease is characterised by metabolic imbalances, particularly in carbohydrates, lipids and lipoproteins, and is frequently associated with severe cardiovascular complications. Among these imbalances, diabetic dyslipidaemia, defined as an increase in triglycerides, a decrease in HDL cholesterol and an increase in small LDL particles , is a key factor in cardiovascular risk in these patients. Unbalanced dietary habits, especially excessive fat and sugar intake, play a crucial role in the onset of dyslipidemia .
Palm oil, a staple dietary fat in tropical countries such as Côte d'Ivoire, has become the focus of increasing research interest because of its saturated fatty acid content. This oil has been the subject of numerous experimental and human studies worldwide . While some studies highlight its impact on the lipid profile, attributed to its richness in saturated fatty acids, particularly palmitic acid , while others have demonstrated its health benefits , particularly due to the antioxidant properties of red palm oil. Despite this work, its use in the diet of patients with chronic diseases remains controversial, as some practitioners advise against its use . In a previous study, we found no significant association between palm oil consumption and hypercholesterolemia in Ivorian subjects . Experimental studies such as Albrahim et al. demonstrated the hypocholesterolemic effects of palm oil in rats with hypercholesterolaemia. Kouakou et al. also studied the effects of palm oil enriched diet on lipid profile and glycemia in Wistar rats in Côte d'Ivoire. However, the impact of palm oil consumption on lipid and lipoprotein metabolism in type 2 diabetic patients remains limited and inconsistent. In West African regions, where palm oil is staple oil, it would be wise to evaluate its impact on lipid and lipoprotein parameters in T2D patients in Abidjan.
2. Materiel and Methods
2.1. Study Population and Sampling
This descriptive and analytical cross-sectional study was conducted over nine months. Participants were T2D patients attending the Endocrinology-Diabetology Unit at the University Hospital. They had controlled blood glucose levels (0.70–1.20 g/L) and glycated haemoglobin levels ≤ 7%. Patients were divided into two groups: palm oil consumers and non-consumers. Patients were aged 30 years and older, of both sexes, and provided verbal and written informed consent. This study was approved by the Scientific Medical Department of the Yopougon University Hospital. The sample size was calculated using Schwartz's formula (1996) . A total of 160 T2D patients with eligible criteria were selected.
2.2. Operational Definition
In the consumer group, the average intake was self-reported and estimated at 150-300 ml of palm oil per day. Frequent consumption was defined as three to four times per week, while occasional consumption corresponded to one to two times per week. Palm oil forms included red palm oil (crude), refined palm oil, both forms combined.
Non-consumers were individuals who ceased using palm oil after medical recommendations or replaced it with other vegetable oils, including olive, sunflower, soybean, or groundnut oil.
2.3. Samples Collection and Biochemical Analysis
Fasting blood samples (10-12 hours) were drawn from the antecubital vein using 5 mL dry tubes, centrifuged at 3000 rpm for 5 minutes. Serum samples were aliquoted and stored at -20°C until analysis. Lipid and lipoprotein parameters were measured using enzymatic methods on a Cobas Integra 400 analyzer (Roche Diagnostics). LDL cholesterol (LDL-c) was calculated using the Friedewald formula. Atherogenicity index was calculated as the ratio of total cholesterol to HDL cholesterol. The reference values for lipid and lipoprotein parameters were total cholesterol < 6.20 mmol/L, LDL-c < 4.12 mmol/L, HDL-c > 1.04 mmol/L, triglycerides < 2.26 mmol/L and a normal atherogenicity index < 5 (Yapo et al., 1990) .
2.4. Ethical Considerations and Confidentiality
The study was approved by the Ivorian National Ethics and Research Committee for Clinical Research (N/Ref: 143/MSHP/CNERkp of 18 January 2018).
2.5. Data Analysis and Statistical Tests
Data were collected using a questionnaire. Lipid and lipoprotein parameters were analysed as categorical variables (normal vs. abnormal). Comparison of proportions was performed using the chi-squared test with a significance level < 0.05.
3. Results
Table 1 concerns distribution of T2D patients according to age range, duration of diabetes, and palm oil consumption habits. The average age was 57.10 ± 11.32 years and the majority of participants were aged over 50 (75.6%). Among them, 76.9% reported consuming palm oil, with a preference for both refined and crude forms (65.1%).
Table 1. Epidemiological characteristics and consumption practices. Epidemiological characteristics and consumption practices. Epidemiological characteristics and consumption practices.

Epidemiologicals characteristics

N=160

%

Age range (years)

<40

12

7.5

[40-50]

27

16.9

[50-60]

53

33.1

≥60

68

42.5

Duration of diabetes (years)

<5

85

53.1

[5-10]

32

20.0

[10-15]

17

10.6

≥15

26

16.3

Palm oil consumption

Yes

123

76.9

No

37

23.1

*Form of consumption

Crude

09

7.3

Refined

34

27.6

Both forms

80

65.1

n: numbers of patients; percentages (%). *The form of consumption variable applies only to participants who reported using palm oil.
A majority of patients with type 2 diabetes had normal levels of total cholesterol (62.5%), triglycerides (80.6%) and a normal TC/HDL ratio (73.5%). Only 45.5% of participants had normal HDL cholesterol levels, while LDL cholesterol was normal in only 46.90% (Figure 1).
Figure 1. Lipid and lipoprotein profile among all patients with type 2 diabetes.Lipid and lipoprotein profile among all patients with type 2 diabetes.
Cholesterol levels were relatively similar in the two groups, normal among palm oil consumers (56.8%) and non-consumers (68.4%), with no significant difference (p=0.137) (Table 2).
Table 2. Comparison of lipid and lipoprotein parameters between palm oil consumers and non-consumers among patients with type 2 diabetes. Comparison of lipid and lipoprotein parameters between palm oil consumers and non-consumers among patients with type 2 diabetes. Comparison of lipid and lipoprotein parameters between palm oil consumers and non-consumers among patients with type 2 diabetes.

Lipid and lipoprotein parameters

Consumption of palm oil

Yes (n; %)

No (n; %)

p-value

Total cholesterol

Normal

46 (56.8)

54 (68.4)

0.137

High

35 (43.2)

25 (31.6)

Triglycerides

Normal

64 (79)

65 (82.3)

0.601

High

17 (21)

14 (17.7)

HDL-c

Normal

33 (40.8)

35 (44.3)

0.649

Low

48 (59.2)

44 (55.7)

LDL-c

Normal

29 (35.8)

30 (38)

0.776

High

52 (64.2)

49 (62)

Atherogenic index

Normal

52 (64.2)

60 (75.9)

0.105

High

29 (35.8)

19 (24.1)

n: numbers; %: percentages, p-values (≤ 0.05) is statistically significant. HDL-c: high-density lipoprotein cholesterol; LDL-c: low-density lipoprotein cholesterol.
The form of palm oil consumed, had no influence on the lipid and lipoprotein parameters studied. Triglycerides levels were normal in 67.3% of patients consuming both types of palm oil, followed by those consuming only refined oil (25.5%) and crude oil (7.1%), with no statistically significant differences observed (p = 0.547) (Table 3). The proportions of normal and low HDL varied in the same direction, regardless of the type of oil consumed (p = 0.630). The frequency of palm oil consumption frequent or occasional had no significant effect on the lipid and lipoprotein parameters studied (p ˃ 0.05) (Table 4).
Table 3. Lipid and lipoprotein parameters according to the form of palm oil consumption among type 2 diabetic (T2D) patients (n = 123). Lipid and lipoprotein parameters according to the form of palm oil consumption among type 2 diabetic (T2D) patients (n = 123). Lipid and lipoprotein parameters according to the form of palm oil consumption among type 2 diabetic (T2D) patients (n = 123).

Lipid and lipoprotein parameters

Form of palm oil consumption

Crude oil (n; %)

Refined oil (n; %)

Both forms (n; %)

p-value

Total cholesterol

Normal

05 (06.7)

23 (30.6)

47 (62.7)

0.633

High

04 (08.3)

11 (22.9)

33 (68.7)

Triglycerides

Normal

05 (07.1)

25 (25.5)

66 (67.3)

0.547

High

02 (08.0)

09 (36)

14 (56.0)

HDL cholesterol

Normal

04 (05.5)

21 (28.8)

48 (65.8)

0.630

Low

05 (10)

13 (26)

48 (64.0)

LDL cholesterol

Normal

04 (09.5)

15 (37.5)

23 (54.8)

0.227

High

05 (06.2)

19 (23.5)

57 (70.4)

Atherogenic index

Normal

08 (09.4)

24 (28.2)

53 (62.4)

0.370

High

01 (02.6)

10 (26.3)

27 (71.1)

Both forms: crude palm oil and refined oil
Table 4. Lipid and lipoprotein parameters according to the frequency of palm oil consumption among type 2 diabetic (T2D) patients (n = 123). Lipid and lipoprotein parameters according to the frequency of palm oil consumption among type 2 diabetic (T2D) patients (n = 123). Lipid and lipoprotein parameters according to the frequency of palm oil consumption among type 2 diabetic (T2D) patients (n = 123).

Lipid and lipoprotein parameters

Frequency of palm oil consumption

Frequent

Occasional

p-value

n=53

%

n=70

%

Total cholesterol

Normal

33

62.3

42

60.0

0.799

High

20

37.7

28

40.0

Triglycerides

Normal

41

77.4

57

81.4

0.579

High

12

22.6

13

18.6

HDL cholesterol

Normal

32

60.4

41

58.6

0.840

Low

21

39.6

29

41.4

LDL cholesterol

Normal

14

26.4

28

40.0

0.116

High

39

73.6

42

60.0

Atherogenic index

Normal

38

71.7

47

67.1

0.588

High

15

28.3

23

32.9

4. Discussion
The average age of participants was 57.1 years (range: 35 to 94 years), is in line with epidemiological data indicating that type 2 diabetes is more common at an advanced age. Ageing is generally associated with decreased insulin sensitivity and increased metabolic risk factors, promoting the onset of this pathology. Furthermore, the majority of patients were women (71.3%), with a sex ratio of 0.40. These observations were in agreement with the results of Arambewela et al. , who reported a mean age of 58 years and a female proportion of 72.7%. Palm oil consumption was high, with the majority of patients (65.1%) using both crude and refined forms. This high prevalence can be explained by the fact that palm oil is an essential part of the Ivorian diet, as Cote d’Ivoire is the second-largest producer of palm oil in Africa after Nigeria .
4.1. Palm Oil Consumption, Lipid and Lipoprotein Profile
Diabetes is a well-established risk factor for cardiovascular diseases (CVD) . Furthermore, dietary fat intake has been implicated in the incidence of CVD and diabetes . In this context, our study explored whether palm oil consumption influences lipid and lipoprotein profiles among individuals with type 2 diabetes. Our findings indicate that palm oil consumption was not associated with significant alterations in total cholesterol levels. These observations were consistent with those of Kouakou et al. , who also reported that palm oil consumption had no significant impact on the overall lipid profile. Berkoh et al. concluded that tropical vegetable oils such as palm oil did not alter the lipid and lipoprotein profile in type 2 diabetic subjects.
Similarly, triglyceride levels did not differ significantly between consumers and non-consumers (p = 0.601). These results are in line with other studies that showed palm oil consumption may reduce or have no impact on blood lipid levels, including triglycerides .
Low HDL-cholesterol levels were prevalent in both groups without a statistically significant difference, possibly reflecting a typical diabetic dyslipidaemia pattern in this population . Previous studies have shown that, compared to other vegetable oils rich in trans fats, palm oil was associated with higher HDL-cholesterol concentrations .
Elevated LDL-cholesterol was common among participants, regardless of palm oil consumption status (64.2% of consumers vs. 62% of non-consumers, p = 0.776). Sun et al reported that palm oil consumption increased LDL cholesterol . This results can be explained by factors such as the dietary fat types intake between West African and Asian populations, genetic backgrounds. In contrast somes experimentals studies demonstrated a reduction in total cholesterol (TC), LDL-c and HDL-c in rats fed palm oil . These findings suggest that palm oil may exert hypocholesterolemic effects, potentially attributable to its high tocotrienol content. Tocotrienols possess potent antioxidant properties and have been shown to confer protective effects against inflammation, and lipid peroxidation .
The atherogenicity index was predominantly normal in both group with no significant difference observed. The presence of bioactive compounds in palm oil, including tocotrienols and phenolic antioxidants, may contribute to its reported cardioprotective properties , consistent with findings by Ajiboye et al. .
4.2. Form and Frequency of Consumption
No significant differences in lipid or lipoprotein parameters were observed according to the form of palm oil consumed (crude, refined, or both). This supports experimental data suggesting that red palm oil may exert antioxidant-mediated lipid-modulating effects, largely attributed to its tocotrienol and phenolic content . Moreover, triglyceride levels remained largely within the normal range among patients consuming both forms (crude and refined palm oil), consistent with previous observations in patients with ischaemic heart disease .
The frequency of palm oil consumption did not significantly influence lipid or lipoprotein profiles. In contrast to reports suggesting that frequent palm oil intake may impair lipid profile , our study showed a comparable level of total cholesterol, triglycerides, HDL-c, LDL-c, and atherogenic index to those consuming it occasionally. This demonstrates that palm oil, when consumed as part of a balanced diet, palm oil may not constitute a major cardiovascular risk factor for populations that use it .
5. Conclusion
Palm oil consumption did not significantly influence the lipid and lipoprotein profiles of patients with type 2 diabetes in this study. Factors such as lifestyle, comorbidities, genetic predisposition, and the overall management of diabetes may play a more important role in lipid and lipoprotein disturbances than simple consumption of palm oil. Further longitudinal and interventional studies are needed to clarify the long-term biochemical effects of palm oil within diabetic diets.
Abbreviations

TC

Total Cholesterol

LDL

Low Density Lipoprotein

HDL

High Density Lipoprotein

T2D

Type 2 Diabetes

Acknowledgments
The authors sincerely thank the Interprofessional Fund for Agricultural Research and Advice (FIRCA) and the Interprofessional Association for the Oil Palm Sector (AIPH) for their support. We would extend our gratitude to the staff of the Endocrinology Department of the Yopougon University Hospital for their invaluable contribution.
Author Contributions
Yapo-Kee Ake Chibrou Benedicte: Writing – original draft
Niamke Amenan Guy Germaine: Writing – review & editing
Ake Ake Alexandre: Formal Analysis, Methodology
Niava-Bouberi Benita: Visualization
Lohore Kouzahon Colombe Jeannine: Software
Ecrabey Yann Christian: Data curation, Investigation
Bamba Youssouf Ben Soualiho: Formal Analysis
N’Guettia Kobenan Alexis: Writing – review & editing
Gauze Gnagne Chantal: Supervision, Validation
Monde Ake Absalome: Conceptualization, Project administration
Funding
This work is not supported by any external funding.
Data Availability Statement
The data supporting the outcome of this research work has been reported in this manuscript.
Conflicts of Interest
The authors declare no conflicts of interest.
References
[1] Sun H, Saeedi P, Karuranga S, Pinkepank M, Ogurtsova K, Duncan BB et al (2022). IDF Diabetes Atlas: Global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045. Diabetes Research and Clinical Practice. 2022, 183: 109119.
[2] Vergès B. Physiopathology of type 2 diabetes dyslipidaemia: new perspectives. Medicine for Metabolic Diseases. 2021, 13: 140-6.
[3] Hernández-Marroquín MÁ, Penney-Amador C, Roy-García IA, Velázquez-López L. Los hábitos de alimentación inadecuados se asocian con la hipercolesterolemia en adolescentes [Inappropriate eating habits are associated with hypercholesterolaemia in adolescents], Medical Journal of the Mexican Social Security Institute, 2024, 62(4): 1-8.
[4] Monde AA, Carbonneau M-A, Michel F, Lauret C, Diabate S, Konan E, et al. Potential health implication of in vitro human LDL vitamin E oxidation modulation by polyphenols deriving from Cote d’Ivoire oil palm species. Journal of Agricultural and Food Chemistry. 2011, 59(17): 9166-71.
[5] Ismail M, Alsalahi A, Imam MU, Ooi DJ, Khaza’ai H, Aljaberi MA, Shamsudin MN, Idrus Z. Safety and neuroprotective efficacy of palm oil and tocotrienol-rich fraction from palm oil: A systematic review. Nutrients. 2020, 12: 521.
[6] Djohan YF, Monde AA, Camara-Cisse M, Badia E, Bonafos B, Fouret G et al. Effects of high-fat diets on inflammation and antioxidant status in rats: comparison between palm olein and olive oil, Acta Biochimica Polonica, 2021, 68(4): 739-44.
[7] Koffi KG, Jover B, Badia E, Djohan YF, Reynaud F, Dere L et al. Study of isoforms of nicotinamide adenine dinucleotide phosphate oxidase of the heart in a model of rats fed on several vegetable oils. African Journal of Biochemistry Research. 2021, 15(3): 49–59.
[8] Albrahim T, Alotaibi MHM, Altamimi NMM, Albariqi AMA, Alqarni LAO, Alassaf SNA, Aloudah HS, Alahmed M, Almnaizel AT, Aldraihem MR et al. The impact of dietary consumption of palm oil and olive oil on lipid profile and hepatocyte injury in hypercholesterolemic rats. Pharmaceuticals. 2022, 15: 1103.
[9] Izuddin, W. I.; Loh, T. C.; Nayan, N.; Akit, H.; Foo, H. L.; Noor, AM. Antioxidant Enzyme System Modulation by Dietary Palm Oils, Palm Kernel Oil and Soybean Oil in Laying Hens. Animals. 2023, 13, 2245.
[10] Ismail SR, Maarof SK, Siedar Ali S, Ali A. Systematic review of palm oil consumption and the risk of cardiovascular disease, PLoS One. 2018, 13(2): e0193533.
[11] Astrup AF, Magkos DM, Bier JT, Brenna MC, de Oliveira Otto JO, Hill JC et al. Saturated fats and health: A reassessment and proposal for food-based recommendations: JACC state-of-the-art-review. Journal of the American College of Cardiology. 2020, 76(7): 844-57.
[12] Edem D. Palm oil: Biochemical, physiological, nutritional, haematological and toxicological aspects: A review. Plant Foods for Human Nutrition. 2002, 57(3): 319-41.
[13] Sundram K, Sambanthamurthi R and Tan YA. Palm fruit chemistry and nutrition. Asia Pacific Journal of Clinical Nutrition. 2003, 12(3): 355-62.
[14] Monde AA, Cisse-Camara, Ake Ake A, Koffi G, Gauze GAC, Djohan YF et al. Biochemical properties, nutritional values, health benefits and sustainability of palm oil. Biochimie. 2020, 178: 81-95.
[15] Zaida Z, Khaza’ai H, Kutty Radhakrishnan A, Chang SK. Therapeutic potential of palm oil vitamin E-derived tocotrienols in inflammation and chronic diseases: evidence from preclinical and clinical studies. Food Research International. 2022, 156: 111175.
[16] Monde AA, Moundounga J-C, Camara-Cisse M, Gauze-Gnagne-Agnero C, Nguetta R, Fogha D et al. Knowledge, attitudes and practices on the nutritional values of palm oil among medical and paramedical personnel at the Abidjan Heart Institute. International Journal of Biological and Chemical Sciences. 2019 13(4): 1969-79.
[17] Yapo ACB, Ake AA, Ahonzo EAAF, Niava B, Lohore JKC, Ecrabey YC et al. Impact of palm oil consumption on hypercholesterolaemia in Ivorian subjects. Advances in Biochemistry. 2024, 12(4): 136-42.
[18] Kouakou AYF, Oussou NJ-B, Kamagate A, Yapo AP. Effect of a diet enriched with palm oil on the serum lipid profile and fasting glycaemia in Wistar rats. Life European Scientific Journal. 2022, 12: 250.
[19] Schwartz D. Statistical Methods for Medical and Biological Sciences (4th Ed.), Lavoisier MSP-Statistics in Biology and Medicine Collection.. 1996, Paris.
[20] Yapo AE, Assayi M, Aka NB, Bonetto R, Comoe L, Lonsdorfer A. Les valeurs de reference de 21 constituants biochimiques sanguins de l’ivoirien adulte presume. African Medical Publications. 1990, 110: 49-57.
[21] Arambewela MH, Somasundaram NP, Jayasekara HBPR, Kumbukage MP, Jayasena PMS, Chandrasekara CMPH et al. Prevalence of chronic complications, their risk factors, and the cardiovascular risk factors among patients with type 2 diabetes attending the diabetic clinic at a tertiary care hospital in Sri Lanka. Journal of Diabetes Research. 2018, (1), 4504287.
[22] USDA (United States Department of Agriculture). Oilseeds: World market and trade. Circular Series October 2024: 1–41. Foreign Agricultural Service, United States Department of Agriculture. 2024.
[23] Goldstein LB. Epidemiology of Cerebrovascular Diseases in Vascular Medicine: A Companion to Braunwald’s Heart Disease, Elsevier Amsterdam. 2019, 361.
[24] Hartley A, Marshall DC, Salciccioli JD, Sikkel MB, Maruthappu M, Shalhoub J. Trends in mortality from ischaemic heart disease and cerebrovascular disease in Europe: 1980 to 2009. Circulation. 2016, 133, 1916-26.
[25] Berkoh DA, Donkoh ET, Asamoah A, Sakibu RA, Owiredu WKBA, Ngala RA. Effect of Tropical Vegetable Oil Consumption on Lipid Profile and Glycaemic Control in Type 2 Diabetics. Trends in Medical Research. 2024, 19(1): 274-84.
[26] Sun G, Xia H, Yang Y, Ma S, Zhou H, Shu G et al (2018). Effects of palm olein and olive oil on serum lipids in a Chinese population: a randomized, double-blind, cross-over trial, Asia Pacific Journal of Clinical Nutrition 27(3): 572-80.
[27] Batai NF, Bitty MLA, Fossou AF, Djetouan KJM, Zahe KYA Amoikon KE. Lipid Profile of a Population of Jacqueville, Consumer of Palm Oil in Southern Cote d’Ivoire. European Journal of Nutrition and Food Safety. 2020, 12(2): 1–10. Article No. EJNFS.55485.
[28] Olabiyi FA, Aboua YG, Monsees TK. Role of red palm oil in male obesity and infertility prevention. Elaeis guineensis. 2022, 43.
[29] Lohore C, Moke L, Yapo-Kee B, Attiegoua B, Adoueni PV, Goun A et al. Association between glycemic control, lipid profile and atherogenic indices in type 2 diabetic patients. EDUCI, African Journal of Endocrinology, Metabolism, and Nutrition. 2022, 7(2).
[30] Sun Y, Neelakantan N, Wu Y, Lote-Oke R, Pan A, van Dam RM. Palm oil consumption increases low-density lipoprotein cholesterol compared with vegetable oils low in saturated fat in a meta-analysis of clinical trials. Journal of Nutrition. 2015, 145(7): 1549–58.
[31] Hoque M, Kabir ME, Hasan MM, Rahman MT, Rashid M, Ruba T, Hossain MM. Biochemical and pathological effects of palm, mustard and soybean oils in rats. Bangladesh Journal of Veterinary Medicine. 2018, 16(1): 107-14.
[32] Looi, A. D., Palanisamy, U. D., Moorthy, M., & Radhakrishnan, A. K. Health Benefits of Palm Tocotrienol-Rich Fraction: A Systematic Review of Randomized Controlled Trials. Nutrition Reviews. 2025, 83(2), 307-328.
[33] Ajiboye JA, Erukainure LO, Lawal BA, Nwachukwu VA, Tugbobo-Amisu AO, Okafor EN et al. Comparative alteration in atherogenic indices and hypocholesteremic effect of palm oil and palm oil mill effluent in normal albino rats. Heliyon. 2015, 1(1), e00010.
[34] Dauquan E, Sani A, Abdullah A, Zalifah M. Effect of different concentrations of red palm olein on blood lipids in rats. International Research Journal of Biochemistry and Bioinformatics. 2011, 1(7): 184–189.
[35] Shah S, Shiekh Y, Lawrence JA, Ezekwueme F, Alam M, Kunwar S et al. A Systematic Review of Effects of Vitamin E on the Cardiovascular System. Cureus. 2021, 13(6): e15616.
[36] Fattore E, Bosetti C, Brighenti F, Agostoni C, Fattore G. Palm oil and blood lipid-related markers of cardiovascular disease: A systematic review and meta-analysis of dietary intervention trials. American Journal of Clinical Nutrition. 2014, 99: 1331-50.
[37] Monde AA, Camara-Cisse M, Konan G., Coulibaly I Adeoti M, Gauze GAC, Hauhouot-attoungbre ML. Effects of palm oil consumption on Lipidic and Lipidoproteinic Profiles with Patients Suffering from Ischemic Heart Pathologies. International Journal of Nutrition and Food Sciences. 2017, 6(1), 6–11.
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    Benedicte, Y. A. C., Germaine, N. A. G., Alexandre, A. A., Chantal, G., Benita, N. B., et al. (2026). Palm Oil Consumption and Serum Lipid and Lipoprotein Profiles in Patients with Type 2 Diabetes in Abidjan. Advances in Biochemistry, 14(1), 1-8. https://doi.org/10.11648/j.ab.20261401.11

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    Benedicte, Y. A. C.; Germaine, N. A. G.; Alexandre, A. A.; Chantal, G.; Benita, N. B., et al. Palm Oil Consumption and Serum Lipid and Lipoprotein Profiles in Patients with Type 2 Diabetes in Abidjan. Adv. Biochem. 2026, 14(1), 1-8. doi: 10.11648/j.ab.20261401.11

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    Benedicte YAC, Germaine NAG, Alexandre AA, Chantal G, Benita NB, et al. Palm Oil Consumption and Serum Lipid and Lipoprotein Profiles in Patients with Type 2 Diabetes in Abidjan. Adv Biochem. 2026;14(1):1-8. doi: 10.11648/j.ab.20261401.11

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  • @article{10.11648/j.ab.20261401.11,
      author = {Yapo-Kee Ake Chibrou Benedicte and Niamke Amenan Guy Germaine and Ake Ake Alexandre and Gauze-Gnagne Chantal and Niava Bouberi Benita and Ecrabey Yann Christian and Lohore Kouzahon Colombe Jeannine and N’Guettia Kobenan Alexis and Bamba Youssouf Ben Soualiho and Koffi Gervais and Monde Ake Absalome},
      title = {Palm Oil Consumption and Serum Lipid and Lipoprotein Profiles in Patients with Type 2 Diabetes in Abidjan},
      journal = {Advances in Biochemistry},
      volume = {14},
      number = {1},
      pages = {1-8},
      doi = {10.11648/j.ab.20261401.11},
      url = {https://doi.org/10.11648/j.ab.20261401.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ab.20261401.11},
      abstract = {Diabetes is a major public health problem, and dietary fat intake plays a significant role in its incidence and progression. The impact of palm oil consumption on lipid and lipoprotein profiles remains controversial, particularly among diabetic patients. This study aimed to assess the influence of palm oil consumption on serum lipid and lipoprotein profiles in patients with type 2 diabetes (T2D) in Abidjan. A cross-sectional study including diabetic patients categorised according to the frequency and form of palm oil consumption was conducted in which total cholesterol (TC), triglycerides (TG), HDL cholesterol (HDL-c), LDL cholesterol (LDL-c) and the atherogenic index were measured and compared between the different groups. The chi-squared test was used with a significance level of p value <0.05. No statistically significant differences were observed between frequent and occasional patient consumers in terms of total cholesterol (p=0.799), triglycerides (p=0.579), HDL-cholesterol (p=0.840), LDL-cholesterol (p=0.116) and atherogenic index (p=0.588). Similarly, the form of palm oil consumed did not significantly influence lipid and lipoprotein profiles. Palm oil consumption, regardless of frequency or form, does not significantly alter the lipid and lipoprotein profile of type 2 diabetic patients. These findings suggest that palm oil intake, within habitual dietary patterns, may not be a primary determinant of dyslipidemia in this population.},
     year = {2026}
    }
    

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  • TY  - JOUR
    T1  - Palm Oil Consumption and Serum Lipid and Lipoprotein Profiles in Patients with Type 2 Diabetes in Abidjan
    AU  - Yapo-Kee Ake Chibrou Benedicte
    AU  - Niamke Amenan Guy Germaine
    AU  - Ake Ake Alexandre
    AU  - Gauze-Gnagne Chantal
    AU  - Niava Bouberi Benita
    AU  - Ecrabey Yann Christian
    AU  - Lohore Kouzahon Colombe Jeannine
    AU  - N’Guettia Kobenan Alexis
    AU  - Bamba Youssouf Ben Soualiho
    AU  - Koffi Gervais
    AU  - Monde Ake Absalome
    Y1  - 2026/01/26
    PY  - 2026
    N1  - https://doi.org/10.11648/j.ab.20261401.11
    DO  - 10.11648/j.ab.20261401.11
    T2  - Advances in Biochemistry
    JF  - Advances in Biochemistry
    JO  - Advances in Biochemistry
    SP  - 1
    EP  - 8
    PB  - Science Publishing Group
    SN  - 2329-0862
    UR  - https://doi.org/10.11648/j.ab.20261401.11
    AB  - Diabetes is a major public health problem, and dietary fat intake plays a significant role in its incidence and progression. The impact of palm oil consumption on lipid and lipoprotein profiles remains controversial, particularly among diabetic patients. This study aimed to assess the influence of palm oil consumption on serum lipid and lipoprotein profiles in patients with type 2 diabetes (T2D) in Abidjan. A cross-sectional study including diabetic patients categorised according to the frequency and form of palm oil consumption was conducted in which total cholesterol (TC), triglycerides (TG), HDL cholesterol (HDL-c), LDL cholesterol (LDL-c) and the atherogenic index were measured and compared between the different groups. The chi-squared test was used with a significance level of p value <0.05. No statistically significant differences were observed between frequent and occasional patient consumers in terms of total cholesterol (p=0.799), triglycerides (p=0.579), HDL-cholesterol (p=0.840), LDL-cholesterol (p=0.116) and atherogenic index (p=0.588). Similarly, the form of palm oil consumed did not significantly influence lipid and lipoprotein profiles. Palm oil consumption, regardless of frequency or form, does not significantly alter the lipid and lipoprotein profile of type 2 diabetic patients. These findings suggest that palm oil intake, within habitual dietary patterns, may not be a primary determinant of dyslipidemia in this population.
    VL  - 14
    IS  - 1
    ER  - 

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Author Information
  • Laboratory of Medical Biochemistry, Felix Houphouet-Boigny University, Abidjan, Côte d’Ivoire;Medical Biochemistry Laboratory, Treichville University Hospital, Abidjan, Côte d’Ivoire

  • Laboratory of Medical Biochemistry, Felix Houphouet-Boigny University, Abidjan, Côte d’Ivoire;Medical Biochemistry Laboratory, Treichville University Hospital, Abidjan, Côte d’Ivoire

  • Laboratory of Medical Biochemistry, Alassane Ouattara University, Bouake, Côte d’Ivoire

  • Laboratory of Medical Biochemistry, Felix Houphouet-Boigny University, Abidjan, Côte d’Ivoire

  • Medical Biochemistry Laboratory, Treichville University Hospital, Abidjan, Côte d’Ivoire

  • Medical Biochemistry Laboratory, Treichville University Hospital, Abidjan, Côte d’Ivoire

  • Medical Biochemistry Laboratory, Treichville University Hospital, Abidjan, Côte d’Ivoire

  • Medical Biochemistry Laboratory, Treichville University Hospital, Abidjan, Côte d’Ivoire

  • Medical Biochemistry Laboratory, Treichville University Hospital, Abidjan, Côte d’Ivoire

  • Laboratory of Medical Biochemistry, Felix Houphouet-Boigny University, Abidjan, Côte d’Ivoire;Medical Biochemistry Laboratory, Treichville University Hospital, Abidjan, Côte d’Ivoire

  • Laboratory of Medical Biochemistry, Felix Houphouet-Boigny University, Abidjan, Côte d’Ivoire;Medical Biochemistry Laboratory, Treichville University Hospital, Abidjan, Côte d’Ivoire

  • Table 1

    Table 1. Epidemiological characteristics and consumption practices. Epidemiological characteristics and consumption practices.

  • Table 2

    Table 2. Comparison of lipid and lipoprotein parameters between palm oil consumers and non-consumers among patients with type 2 diabetes. Comparison of lipid and lipoprotein parameters between palm oil consumers and non-consumers among patients with type 2 diabetes.

  • Table 3

    Table 3. Lipid and lipoprotein parameters according to the form of palm oil consumption among type 2 diabetic (T2D) patients (n = 123). Lipid and lipoprotein parameters according to the form of palm oil consumption among type 2 diabetic (T2D) patients (n = 123).

  • Table 4

    Table 4. Lipid and lipoprotein parameters according to the frequency of palm oil consumption among type 2 diabetic (T2D) patients (n = 123). Lipid and lipoprotein parameters according to the frequency of palm oil consumption among type 2 diabetic (T2D) patients (n = 123).