Retrospective Analysis of Three Different Methods for the Treatment of Macrolide-Unresponsive Mycoplasma Pneumoniae Pneumonia in Children

Wan Linfang

doi:doi:10.11648/j.ajcem.20231105.12

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Retrospective Analysis of Three Different Methods for the Treatment of Macrolide-Unresponsive Mycoplasma Pneumoniae Pneumonia in Children

Wan Linfang

Published in American Journal of Clinical and Experimental Medicine (Volume 11, Issue 5)

Received: 23 October 2023 Accepted: 6 November 2023 Published: 9 November 2023

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Abstract

Mycoplasma pneumoniae (MP) is an important cause of community-acquired pneumonia in children and adolescents. We screened 52 children with macrolide-unresponsive Mycoplasma pneumoniae pneumonia hospitalized at our institution from April 2023 to August 2023, and counted and evaluated their treatment modalities and efficacy. Based on the three different drug treatments, we divided all the children into four groups: Group A was the azithromycin oral sequential + glucocorticoid treatment effective group; Group B was the doxycycline oral treatment effective group; Group C was the doxycycline oral + glucocorticoid effective group. By χ2 test, Kruskal-Wallis test, and ann-WhitneyU rank-sum test, we compared the effective cure rate, adjusted hospitalization days, effective fever recovery time, and pulmonary imaging regression under different treatment modalities. We chose three groups of treatment effective cases, A, B and C to analyze. There was no statistically significant difference in the effective cure rate among the three effective groups, P > 0.05; There was a statistically significant difference in the number of adjusted hospitalization days, p < 0.05; There was a statistical difference in the number of adjusted hospitalization days between groups A and B, P < 0.05; There was a statistical difference in the number of adjusted hospitalization days between groups A and C, P < 0.05; There was no statistically significant difference in the number of adjusted hospitalization days between groups B and C, P > 0.05; There was no statistical difference in effective temperature recovery time or lung imaging outcomes among the three groups. From the study, we conclude that the choice of doxycycline or doxycycline and hormone therapy can shorten the number of days of hospitalization and achieve clinical cure more quickly.

Published in	American Journal of Clinical and Experimental Medicine (Volume 11, Issue 5)
DOI	10.11648/j.ajcem.20231105.12
Page(s)	92-96
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Macrolide-Unresponsive Mycoplasma Pneumoniae Pneumonia, Doxycycline, Azithromycin, Glucocorticoid

References

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APA Style

Linfang, W. (2023). Retrospective Analysis of Three Different Methods for the Treatment of Macrolide-Unresponsive Mycoplasma Pneumoniae Pneumonia in Children. American Journal of Clinical and Experimental Medicine, 11(5), 92-96. https://doi.org/10.11648/j.ajcem.20231105.12

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ACS Style

Linfang, W. Retrospective Analysis of Three Different Methods for the Treatment of Macrolide-Unresponsive Mycoplasma Pneumoniae Pneumonia in Children. Am. J. Clin. Exp. Med. 2023, 11(5), 92-96. doi: 10.11648/j.ajcem.20231105.12

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AMA Style

Linfang W. Retrospective Analysis of Three Different Methods for the Treatment of Macrolide-Unresponsive Mycoplasma Pneumoniae Pneumonia in Children. Am J Clin Exp Med. 2023;11(5):92-96. doi: 10.11648/j.ajcem.20231105.12

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@article{10.11648/j.ajcem.20231105.12,
  author = {Wan Linfang},
  title = {Retrospective Analysis of Three Different Methods for the Treatment of Macrolide-Unresponsive Mycoplasma Pneumoniae Pneumonia in Children},
  journal = {American Journal of Clinical and Experimental Medicine},
  volume = {11},
  number = {5},
  pages = {92-96},
  doi = {10.11648/j.ajcem.20231105.12},
  url = {https://doi.org/10.11648/j.ajcem.20231105.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajcem.20231105.12},
  abstract = {Mycoplasma pneumoniae (MP) is an important cause of community-acquired pneumonia in children and adolescents. We screened 52 children with macrolide-unresponsive Mycoplasma pneumoniae pneumonia hospitalized at our institution from April 2023 to August 2023, and counted and evaluated their treatment modalities and efficacy. Based on the three different drug treatments, we divided all the children into four groups: Group A was the azithromycin oral sequential + glucocorticoid treatment effective group; Group B was the doxycycline oral treatment effective group; Group C was the doxycycline oral + glucocorticoid effective group. By χ2 test, Kruskal-Wallis test, and ann-WhitneyU rank-sum test, we compared the effective cure rate, adjusted hospitalization days, effective fever recovery time, and pulmonary imaging regression under different treatment modalities. We chose three groups of treatment effective cases, A, B and C to analyze. There was no statistically significant difference in the effective cure rate among the three effective groups, P > 0.05; There was a statistically significant difference in the number of adjusted hospitalization days, p  0.05; There was no statistical difference in effective temperature recovery time or lung imaging outcomes among the three groups. From the study, we conclude that the choice of doxycycline or doxycycline and hormone therapy can shorten the number of days of hospitalization and achieve clinical cure more quickly.
},
 year = {2023}
}

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TY  - JOUR
T1  - Retrospective Analysis of Three Different Methods for the Treatment of Macrolide-Unresponsive Mycoplasma Pneumoniae Pneumonia in Children
AU  - Wan Linfang
Y1  - 2023/11/09
PY  - 2023
N1  - https://doi.org/10.11648/j.ajcem.20231105.12
DO  - 10.11648/j.ajcem.20231105.12
T2  - American Journal of Clinical and Experimental Medicine
JF  - American Journal of Clinical and Experimental Medicine
JO  - American Journal of Clinical and Experimental Medicine
SP  - 92
EP  - 96
PB  - Science Publishing Group
SN  - 2330-8133
UR  - https://doi.org/10.11648/j.ajcem.20231105.12
AB  - Mycoplasma pneumoniae (MP) is an important cause of community-acquired pneumonia in children and adolescents. We screened 52 children with macrolide-unresponsive Mycoplasma pneumoniae pneumonia hospitalized at our institution from April 2023 to August 2023, and counted and evaluated their treatment modalities and efficacy. Based on the three different drug treatments, we divided all the children into four groups: Group A was the azithromycin oral sequential + glucocorticoid treatment effective group; Group B was the doxycycline oral treatment effective group; Group C was the doxycycline oral + glucocorticoid effective group. By χ2 test, Kruskal-Wallis test, and ann-WhitneyU rank-sum test, we compared the effective cure rate, adjusted hospitalization days, effective fever recovery time, and pulmonary imaging regression under different treatment modalities. We chose three groups of treatment effective cases, A, B and C to analyze. There was no statistically significant difference in the effective cure rate among the three effective groups, P > 0.05; There was a statistically significant difference in the number of adjusted hospitalization days, p  0.05; There was no statistical difference in effective temperature recovery time or lung imaging outcomes among the three groups. From the study, we conclude that the choice of doxycycline or doxycycline and hormone therapy can shorten the number of days of hospitalization and achieve clinical cure more quickly.

VL  - 11
IS  - 5
ER  -

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Author Information

Wan Linfang

Department of Pediatrics, The First Affiliated Hospital of Yangtze University, Jingzhou, China

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Plain Text BibTeX RIS

APA Style

Linfang, W. (2023). Retrospective Analysis of Three Different Methods for the Treatment of Macrolide-Unresponsive Mycoplasma Pneumoniae Pneumonia in Children. American Journal of Clinical and Experimental Medicine, 11(5), 92-96. https://doi.org/10.11648/j.ajcem.20231105.12

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ACS Style

Linfang, W. Retrospective Analysis of Three Different Methods for the Treatment of Macrolide-Unresponsive Mycoplasma Pneumoniae Pneumonia in Children. Am. J. Clin. Exp. Med. 2023, 11(5), 92-96. doi: 10.11648/j.ajcem.20231105.12

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AMA Style

Linfang W. Retrospective Analysis of Three Different Methods for the Treatment of Macrolide-Unresponsive Mycoplasma Pneumoniae Pneumonia in Children. Am J Clin Exp Med. 2023;11(5):92-96. doi: 10.11648/j.ajcem.20231105.12

Copy | Download

@article{10.11648/j.ajcem.20231105.12,
  author = {Wan Linfang},
  title = {Retrospective Analysis of Three Different Methods for the Treatment of Macrolide-Unresponsive Mycoplasma Pneumoniae Pneumonia in Children},
  journal = {American Journal of Clinical and Experimental Medicine},
  volume = {11},
  number = {5},
  pages = {92-96},
  doi = {10.11648/j.ajcem.20231105.12},
  url = {https://doi.org/10.11648/j.ajcem.20231105.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajcem.20231105.12},
  abstract = {Mycoplasma pneumoniae (MP) is an important cause of community-acquired pneumonia in children and adolescents. We screened 52 children with macrolide-unresponsive Mycoplasma pneumoniae pneumonia hospitalized at our institution from April 2023 to August 2023, and counted and evaluated their treatment modalities and efficacy. Based on the three different drug treatments, we divided all the children into four groups: Group A was the azithromycin oral sequential + glucocorticoid treatment effective group; Group B was the doxycycline oral treatment effective group; Group C was the doxycycline oral + glucocorticoid effective group. By χ2 test, Kruskal-Wallis test, and ann-WhitneyU rank-sum test, we compared the effective cure rate, adjusted hospitalization days, effective fever recovery time, and pulmonary imaging regression under different treatment modalities. We chose three groups of treatment effective cases, A, B and C to analyze. There was no statistically significant difference in the effective cure rate among the three effective groups, P > 0.05; There was a statistically significant difference in the number of adjusted hospitalization days, p  0.05; There was no statistical difference in effective temperature recovery time or lung imaging outcomes among the three groups. From the study, we conclude that the choice of doxycycline or doxycycline and hormone therapy can shorten the number of days of hospitalization and achieve clinical cure more quickly.
},
 year = {2023}
}

Copy | Download

TY  - JOUR
T1  - Retrospective Analysis of Three Different Methods for the Treatment of Macrolide-Unresponsive Mycoplasma Pneumoniae Pneumonia in Children
AU  - Wan Linfang
Y1  - 2023/11/09
PY  - 2023
N1  - https://doi.org/10.11648/j.ajcem.20231105.12
DO  - 10.11648/j.ajcem.20231105.12
T2  - American Journal of Clinical and Experimental Medicine
JF  - American Journal of Clinical and Experimental Medicine
JO  - American Journal of Clinical and Experimental Medicine
SP  - 92
EP  - 96
PB  - Science Publishing Group
SN  - 2330-8133
UR  - https://doi.org/10.11648/j.ajcem.20231105.12
AB  - Mycoplasma pneumoniae (MP) is an important cause of community-acquired pneumonia in children and adolescents. We screened 52 children with macrolide-unresponsive Mycoplasma pneumoniae pneumonia hospitalized at our institution from April 2023 to August 2023, and counted and evaluated their treatment modalities and efficacy. Based on the three different drug treatments, we divided all the children into four groups: Group A was the azithromycin oral sequential + glucocorticoid treatment effective group; Group B was the doxycycline oral treatment effective group; Group C was the doxycycline oral + glucocorticoid effective group. By χ2 test, Kruskal-Wallis test, and ann-WhitneyU rank-sum test, we compared the effective cure rate, adjusted hospitalization days, effective fever recovery time, and pulmonary imaging regression under different treatment modalities. We chose three groups of treatment effective cases, A, B and C to analyze. There was no statistically significant difference in the effective cure rate among the three effective groups, P > 0.05; There was a statistically significant difference in the number of adjusted hospitalization days, p  0.05; There was no statistical difference in effective temperature recovery time or lung imaging outcomes among the three groups. From the study, we conclude that the choice of doxycycline or doxycycline and hormone therapy can shorten the number of days of hospitalization and achieve clinical cure more quickly.

VL  - 11
IS  - 5
ER  -

Copy | Download