Research Article | | Peer-Reviewed

Therapeutic Compliance Among Chronic HBV Carriers in Burkina Faso, 2021 - 2023

Received: 30 September 2025     Accepted: 20 October 2025     Published: 28 November 2025
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Abstract

Background: Non-compliance with treatment is a major obstacle to reducing the morbidity and mortality of hepatitis B. According to the World Health Organization, solving the problem of non-compliance with treatment would represent significant progress. Burkina is a country with high endemicity and the factors associated with non-compliance with treatment remain poorly understood. Objective: This study aims to identify these factors and guide strategies. Methodology: This was a retrospective cohort study of 210 chronic carriers of hepatitis B from 2021-2023 in Burkina. The average scores for compliance with hygiene and dietary measures, compliance with medication intake and follow-up at the 6th; 12th, 18th, 24th month of our study were calculated. We speak of non-compliance with treatment if this average is < 75%. We conducted interviews with patients and performed a documentary review to collect data. The data were processed and analyzed by SAS 9.4® software. Results: The incidence of therapeutic non-compliance was 47.9%, including 60.9% among participants with a monthly income of less than 200,000 FCFA compared to 33.3% among those with an income greater than or equal to 200,000 FCFA. Adjusted for the values present, the factors associated with therapeutic non-compliance are monthly income <200,000 FCFA (p-value = 0.0066), inadequate knowledge of hepatitis B (p-value = 0.0440), age ≥ 50 years (p-value = 0.0191) and male gender (p-value = 0.0256). Conclusion: Hepatitis B treatment non-compliance remains a public health problem in Burkina. Factors associated with non-compliance include low income, inadequate knowledge of hepatitis B, age and gender. Addressing this requires making care more affordable, increasing awareness, diagnostic and management capacities.

Published in Science Journal of Public Health (Volume 13, Issue 6)
DOI 10.11648/j.sjph.20251306.11
Page(s) 321-329
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2025. Published by Science Publishing Group

Keywords

Hepatitis B, Chronicity, Treatment Compliance, Burkina Faso

References
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Cite This Article
  • APA Style

    Yanogo, P. K., Sanou, E. N., Traore, I. T., Kabore, J., Balima, C., et al. (2025). Therapeutic Compliance Among Chronic HBV Carriers in Burkina Faso, 2021 - 2023. Science Journal of Public Health, 13(6), 321-329. https://doi.org/10.11648/j.sjph.20251306.11

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    ACS Style

    Yanogo, P. K.; Sanou, E. N.; Traore, I. T.; Kabore, J.; Balima, C., et al. Therapeutic Compliance Among Chronic HBV Carriers in Burkina Faso, 2021 - 2023. Sci. J. Public Health 2025, 13(6), 321-329. doi: 10.11648/j.sjph.20251306.11

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    AMA Style

    Yanogo PK, Sanou EN, Traore IT, Kabore J, Balima C, et al. Therapeutic Compliance Among Chronic HBV Carriers in Burkina Faso, 2021 - 2023. Sci J Public Health. 2025;13(6):321-329. doi: 10.11648/j.sjph.20251306.11

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  • @article{10.11648/j.sjph.20251306.11,
      author = {Pauline Kiswendsida Yanogo and Estelle Nadine Sanou and Isidore Tiandiogo Traore and Jean Kabore and Clarisse Balima and Djibril Barry and Hermann Yoda and Hermann Nikiema and Smaila Ouedraogo and Nicolas Meda},
      title = {Therapeutic Compliance Among Chronic HBV Carriers in Burkina Faso, 2021 - 2023},
      journal = {Science Journal of Public Health},
      volume = {13},
      number = {6},
      pages = {321-329},
      doi = {10.11648/j.sjph.20251306.11},
      url = {https://doi.org/10.11648/j.sjph.20251306.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjph.20251306.11},
      abstract = {Background: Non-compliance with treatment is a major obstacle to reducing the morbidity and mortality of hepatitis B. According to the World Health Organization, solving the problem of non-compliance with treatment would represent significant progress. Burkina is a country with high endemicity and the factors associated with non-compliance with treatment remain poorly understood. Objective: This study aims to identify these factors and guide strategies. Methodology: This was a retrospective cohort study of 210 chronic carriers of hepatitis B from 2021-2023 in Burkina. The average scores for compliance with hygiene and dietary measures, compliance with medication intake and follow-up at the 6th; 12th, 18th, 24th month of our study were calculated. We speak of non-compliance with treatment if this average is Results: The incidence of therapeutic non-compliance was 47.9%, including 60.9% among participants with a monthly income of less than 200,000 FCFA compared to 33.3% among those with an income greater than or equal to 200,000 FCFA. Adjusted for the values present, the factors associated with therapeutic non-compliance are monthly income Conclusion: Hepatitis B treatment non-compliance remains a public health problem in Burkina. Factors associated with non-compliance include low income, inadequate knowledge of hepatitis B, age and gender. Addressing this requires making care more affordable, increasing awareness, diagnostic and management capacities.},
     year = {2025}
    }
    

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  • TY  - JOUR
    T1  - Therapeutic Compliance Among Chronic HBV Carriers in Burkina Faso, 2021 - 2023
    AU  - Pauline Kiswendsida Yanogo
    AU  - Estelle Nadine Sanou
    AU  - Isidore Tiandiogo Traore
    AU  - Jean Kabore
    AU  - Clarisse Balima
    AU  - Djibril Barry
    AU  - Hermann Yoda
    AU  - Hermann Nikiema
    AU  - Smaila Ouedraogo
    AU  - Nicolas Meda
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    DO  - 10.11648/j.sjph.20251306.11
    T2  - Science Journal of Public Health
    JF  - Science Journal of Public Health
    JO  - Science Journal of Public Health
    SP  - 321
    EP  - 329
    PB  - Science Publishing Group
    SN  - 2328-7950
    UR  - https://doi.org/10.11648/j.sjph.20251306.11
    AB  - Background: Non-compliance with treatment is a major obstacle to reducing the morbidity and mortality of hepatitis B. According to the World Health Organization, solving the problem of non-compliance with treatment would represent significant progress. Burkina is a country with high endemicity and the factors associated with non-compliance with treatment remain poorly understood. Objective: This study aims to identify these factors and guide strategies. Methodology: This was a retrospective cohort study of 210 chronic carriers of hepatitis B from 2021-2023 in Burkina. The average scores for compliance with hygiene and dietary measures, compliance with medication intake and follow-up at the 6th; 12th, 18th, 24th month of our study were calculated. We speak of non-compliance with treatment if this average is Results: The incidence of therapeutic non-compliance was 47.9%, including 60.9% among participants with a monthly income of less than 200,000 FCFA compared to 33.3% among those with an income greater than or equal to 200,000 FCFA. Adjusted for the values present, the factors associated with therapeutic non-compliance are monthly income Conclusion: Hepatitis B treatment non-compliance remains a public health problem in Burkina. Factors associated with non-compliance include low income, inadequate knowledge of hepatitis B, age and gender. Addressing this requires making care more affordable, increasing awareness, diagnostic and management capacities.
    VL  - 13
    IS  - 6
    ER  - 

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